[Deficit of anticoagulant factors, endothelial stress and thrombophilia].

Abstract:

:Thrombophilia is characterised by elevated thrombotic and embolic risk and may be caused by congenital or acquired coagulating inhibitor deficit. A young man was repeatedly admitted to Emergency Medicine Units because of pain, oedema and slight functional impairment of the left leg, and recurrent thrombophlebitis was diagnosed. During the most recent hospitalization, vena cava thrombosis was diagnosed and therapeutic management consisted of application of a caval filter and administration of dicoumarin anticoagulants. This case can be classified as a hereditary protein S deficiency with APC-resistance. However, non-strenuous, protracted and repeated physical trauma may have acted synergically with the congenital coagulation inhibitor deficiency, determining the thrombotic episodes, which are probably provoked by transient and functional alterations of the non-thrombogenic properties of the endothelium.

journal_name

Minerva Cardioangiol

authors

Neri S,Ierna D,Sfogliano L

subject

Has Abstract

pub_date

1997-10-01 00:00:00

pages

503-7

issue

10

eissn

0026-4725

issn

1827-1618

journal_volume

45

pub_type

杂志文章
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    authors: Minutiello L

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    doi:

    authors: Del Bene MR,Barletta G

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    doi:

    authors: Martinelli MM,Dragagna G,Vitali A,Fedele F

    更新日期:2003-02-01 00:00:00

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    authors: Laurora G,Cesarone MR,De Sanctis MT,Belcaro G

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    pub_type: 杂志文章

    doi:

    authors: Fuchs U,Murray E,Gueldner H,Tenderich G,Minami K,Koerfer R

    更新日期:2006-08-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:

    authors: Luckie M,Khattar RS

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    pub_type: 杂志文章

    doi:

    authors: Butera A,Lupia Palmieri G,Pelaggi P,Vitale U,Ferlaino G

    更新日期:1993-12-01 00:00:00

  • [Dissolution of a right cardiac migrant thromboembolus in pulmonary embolism after treatment with rt-PA. Report of a successfully treated case].

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    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章

    doi:

    authors: Minutiello L

    更新日期:1993-01-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Taccola A,Zambelli M

    更新日期:2000-04-01 00:00:00

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    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章,评审

    doi:

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    更新日期:2005-10-01 00:00:00

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    pub_type: 杂志文章

    doi:

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    pub_type: 临床试验,杂志文章

    doi:

    authors: Pomini G,Salvo P,Torchiarella C,Lucangeli A,Ruffatti A,Naso A,Gribaldo R

    更新日期:1997-04-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:

    authors: Cacciapuoti F

    更新日期:2001-10-01 00:00:00

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    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章

    doi:

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    pub_type: 杂志文章

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    authors: Varma A,Appleton DL,Nusca A,Lipinski MJ,Goudreau E,Cowley MJ,Wittkamp M,Vetrovec GW,Abbate A

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    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章

    doi:

    authors: Melina D,Colivicchi F,Melina G,Pristipino C

    更新日期:1993-07-01 00:00:00

  • Low molecular weight heparins in cardiovascular medicine.

    abstract::Cardiovascular diseases are the major cause of morbidity and mortality in the Western countries and their prevalence is increasing in developing world. The final biological evolution of atherosclerotic process, supporting development and progression of cardiovascular diseases, is thrombosis. In the most recent years s...

    journal_title:Minerva cardioangiologica

    pub_type: 杂志文章,评审

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    authors: De Lorenzo F,Dotsenko O,Kakkar VV

    更新日期:2005-12-01 00:00:00

  • [Thrombophilia and pregnancy].

    abstract::The risk of venous thromboembolism (VTE) increases up to 5-10-fold during pregnancy and VTE represents the first cause of maternal mortality. The annual incidence of VTE is 0.97 per 1000 women during pregnancy and 7.19 per 1000 in the puerperium. The risk is higher in carriers of inherited thrombophilia. Prophylaxis o...

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    更新日期:2006-12-01 00:00:00

  • Statins in primary prevention: impact on mortality. A meta-analysis study.

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  • [Balanced beta--alpha-blocker treatment with carvedilol in mild-moderate arterial hypertension].

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    pub_type: 杂志文章,评审

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    doi:

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  • Current trends in palliative heart care.

    abstract::Palliative care is an alternate therapeutic approach that involves specialised medical care of a patient diagnosed with serious life threatening illness like heart failure (HF). The prime aim of the palliative care is to provide patient with relief from the symptoms, pain, physical stress, and mental stress of the dia...

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  • [Treatment of post-transplant erythrocytosis: comparison of lisinopril and theophylline].

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    doi:

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  • Ventricular tachycardia in "end stage" hypertrophic cardiomyopathy: a role of dronedarone.

    abstract::Hypertrophic cardiomyopathy (HCM) occurs in 1 in every 500 individuals. It represents the most common cause of sudden cardiac death in those under the age of twenty-five. 3-5% patients with HCM go on to develop the dilated, hypokinetic end stage (ES) HCM with systolic failure. They have a higher incidence of heart fai...

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    pub_type: 杂志文章

    doi:

    authors: Nanda S,Levin V,Martinez MW

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  • [Chiari's network: persistence of the embryonic remnants of the valve of the sinus venosus in the right atrium. Echocardiographic and clinical analysis in a group of subjects].

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