Abstract:
AIM:It is not known whether therapy assisted by determinations of serum B-type natriuretic peptide (BNP) may improve the outcome for outpatients with chronic heart failure (CHF). METHODS:A retrospective case-control study was carried out, enrolling patients with acutely decompensated heart failure (ADHF) who were followed up for a mean period of four months. The patients who had died or had new episodes of ADHF were studied as the cases. For each case, one living patient who was free from ADHF-related re-hospitalisations was recruited as control. Cases and controls were also matched for some variables to minimise possible confounding. The possible role of BNP-guided therapy as a predictor of decreased risk of deaths or new hospitalisations related to heart failure was explored. RESULTS:Twenty-eight cases and 44 controls were enrolled. A fall in BNP on the fifth day after admission was found to be a predictor of a decreased risk of the composite endpoint "death or new hospitalisation, heart failure-related" (hazard ratio=0.1508; 95% CI: 0.049 to 0.463; P=0.001). On the other hand, low glomerular filtration rate at admission (<60 mL/min/1.73 m2) was associated with increased risk of the abovementioned endpoint (hazard ratio=7.1785; 95% CI: 1.574 to 32.725; P=0.0113). On the contrary, BNP-guided therapy was associated with a similar risk of death and/or CHF-related hospitalisation, compared to the conventional clinical approach. CONCLUSION:A fall in BNP ≥60% from baseline on the fifth day after admission was found to be associated with a favorable clinical outcome in outpatients with CHF after four months of follow-up, irrespective whether this finding had been detected in patients treated according to the BNP-guided therapy or in patients treated with conventional clinical criteria. However, among the outpatients with previous ADHF, a substantial improvement in cardiovascular event rates could not be demonstrated in those treated with BNP-guided therapy compared with those undergoing usual, symptom-guided treatment.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
De Vecchis R,Esposito C,Di Biase G,Ariano Csubject
Has Abstractpub_date
2013-08-01 00:00:00pages
437-49issue
4eissn
0026-4725issn
1827-1618pii
R05Y2013N04A0437journal_volume
61pub_type
杂志文章abstract:BACKGROUND:Sutureless aortic valve prostheses have the potential to augment the adoption of alternative incision approaches for aortic valve replacement (AVR). Still, we lack the evidence on which surgical approach is best associated with sutureless AVR. METHODS:Data on 483 patients undergoing sutureless small incisio...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.17.04568-6
更新日期:2018-04-01 00:00:00
abstract::Calcium-antagonist and B-blockers are effective in improving exercise tolerance in patients with effort angina. We studied the short effects of oral administration of nifedipine (10 mg) and propranolol (80 mg) alone and in combination in 15 elderly patients with chronic exertional angina pectoris in a double-blind, ra...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-04-01 00:00:00
abstract:UNLABELLED:To test if a low Q wave voltage and its faulty increase after exercise is an additional sign of myocardial ischemia, 64 pts with no previous myocardial infarction, bundle branch block or left ventricular hypertrophy were studied by a treadmill test and coronary angiography. Nineteen had single vessel disease...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the effects of low-dose niacin extended-release (niacin-ER) combined with simvastatin (SV) in the treatment of patients with mixed dyslipidemia who have not normalized their lipid profile with statin therapy alone. METHODS:A prospective, clinical trial of 35 patients with mixe...
journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract::We report a case of a 86-year-old woman, with a 1-year history of pain during walking and standing; a duplex scanning of the popliteal fossa was performed bilaterally. We pointed out the presence of a bilateral popliteal vein aneurysm, partially thrombosed. She was treated only with oral anticoaugulant therapy, becaus...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract:AIM:Studies on percutaneous transluminal cardiac angioplasty (PTCA) in patients with end stage renal disease (ESRD) on hemodialysis have suggested high rates of procedural complications and restenosis. Bare metal stent percutaneous coronary intervention (PCI) has significantly reduced restenosis and subsequent target l...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,meta分析,评审
doi:
更新日期:2009-06-01 00:00:00
abstract::Deep venous thrombosis (DVT) is often difficult to diagnose based on objective data alone (sensitivity 60-66%, specificity 20-72%, according to a number of studies) and this leads to the possible misuse of instrumental tests. It is important to establish standard clinical protocols to select those cases that call for ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::Congenital thrombophilia, specifically thrombophilia due to Leiden modified factor V as the cause of thromboembolic disease, is discussed. Thromboembolic disease is potentially fatal and disabling. A clinical case is presented of a girl of 15 with Leiden factor V thrombophilia in which all the typical thromboembolic e...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The aim of this prospective supplement summer registry study was to evaluate the efficacy of Pycnogenol® in controlling symptoms of chronic venous insufficiency (CVI) and microcirculatory parameters: venous hypertension and microangiopathy. Pycnogenol® (Horphag Research) is the standardized extract of the ba...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.19.04948-X
更新日期:2019-08-01 00:00:00
abstract::Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which recently has been characterized as a pandemic by the World Health Organization (WHO) having killed almost 250,000 people worldwide as of May 4th, 2020. Despite the fact that SARS-CoV-2 seem...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.20.05298-6
更新日期:2020-08-01 00:00:00
abstract::Palliative care is an alternate therapeutic approach that involves specialised medical care of a patient diagnosed with serious life threatening illness like heart failure (HF). The prime aim of the palliative care is to provide patient with relief from the symptoms, pain, physical stress, and mental stress of the dia...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-02-01 00:00:00
abstract::The Authors report their experience of the surgical treatment of cardiac prosthetic endocarditis. Between September 1974 and December 1988, 2,796 cardiac prostheses were implanted. An endocarditis in the follow-up of 23 patients involving 27 prostheses was diagnosed. The operative mortality was high in patients with m...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract::With radioisotopes it is possible to study the heart obtaining complementary or substitutive informations to those provided by the most common noninvasive methods of myocardial assessment and by coronarography. This paper aim is to report experience with thallium 201 and 99mTc isonitrile in the diagnosis and followup ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The authors present the results of a research on 3,888 patients (1,768 males and 2,120 females) admitted to the 1st Internal Medicine Department of Leghorn Hospital during two years (from July 1993 to June 1995). The research is intended to value the hyperlipidaemia's incidence in hospitalized patients, and the associ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::In recent years, it has become increasingly recognised that a central feature of the disease progression associated with heart failure is the process of left ventricular remodeling. The remodeling process manifests as an increase in left ventricular volumes, leading to a rise in wall stress and a compensatory increase...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2003-04-01 00:00:00
abstract::Atrial fibrillation is the most common cardiac arrhythmia and the most frequent cause of hospitalization and utilization expense among all heart diseases. Taking into account persistent atrial fibrillation we know that, in order to cardiovert persistent atrial fibrillation, external direct current cardioversion is the...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2004-04-01 00:00:00
abstract::We have verified the utility of echo-dipyridamole test in the diagnosis of chest pain of unsure origin, especially in patients who cannot be quickly submitted to exercise stress test because of permanent abnormalities at basal ECG or because of clinical reasons. 17 patients with chest pain, abnormalities at basal ECG ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:Ehen refractory to optimal medical treatment cardiogenic pulmonary edema requires mechanical ventilation as a last therapeutic resource. In recent years an increasing number of authors reported their experience in the management of acute or subacute respiratory failure with non-invasive mechanical ventilatio...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract::The dilatation of the vascular grafts is a well known phenomenon. It is usually evaluated by means of ultrasounds or, in selected cases, by CT scans or MRI; nevertheless its characteristics are far beyond to be fully recognized. Following our promising preliminary experience with helical CT as sole preoperative imagin...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::The risk of venous thromboembolism (VTE) increases up to 5-10-fold during pregnancy and VTE represents the first cause of maternal mortality. The annual incidence of VTE is 0.97 per 1000 women during pregnancy and 7.19 per 1000 in the puerperium. The risk is higher in carriers of inherited thrombophilia. Prophylaxis o...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2006-12-01 00:00:00
abstract:AIM:The aim of this study was to analyze restenosis after percutaneous coronary intervention, factors related to restenosis after coronary artery stenting and the degree of the risk of restenosis were evaluated. METHODS:The study enrolled 181 patients (249 lesions) who underwent the first coronary artery stenting. Mul...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract::The decision to offer patients with myocardial ischemia a coronary artery bypass graft (CABG) surgery has been largely determined by extent of coronary artery disease (CAD) and left ventricular function, since the early 1970's. Based upon subset analyses, and long-term follow-up, of three moderate-sized trials of stab...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2006-10-01 00:00:00
abstract::The aneurysm of the interatrial septum (ASA) is a rare congenital heart disease, easily recognizable by real time cross sectional two dimensional echocardiography. The ASA occurs as an isolated entity or may be associated with congenital heart disease. Usually ASA may cause serious complications such as embolic phenom...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::This paper presents a study of plethysmographic changes induced by methacholine (a derivative of acetylcholine) administered via iontophoresis in a population of 41 young women with apparently primary Raynaud's disease. All patients presented with a very clear statistically significant sphygmic increment, obviously co...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract:AIM:Paroxysmal supraventricular tachycardia (PSVT) is a very frequent type of arrhythmia. Atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia through extranodal accessory pathways (AVRT) are the most common types of paroxysmal supraventricular tachycardia. We describe...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::The ability of interventional cardiologists to identify high-risk percutaneous coronary intervention (PCI) patients, requires the integration of different features belonging to medical history, organ damage, coronary anatomy and the nature of the acute event. The selection of a subgroup of patients that could benefit ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.18.04678-9
更新日期:2018-10-01 00:00:00
abstract::Chronic vascular disorders of the upper limbs are not frequently encountered in women; in addition, advanced age of onset tends to suggest the presence of common diseases such as arteriosclerosis or microembolization. Nonetheless, diagnosis is not always straightforward and in some cases both-laboratory and instrument...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::Pathophysiological remodeling of cardiac function occurs at multiple levels, spanning the spectrum from molecular and sub-cellular changes to those occurring at the organ-system levels. Of key importance to arrhythmias are changes in the electrophysiological substrate at the tissue level. In this manuscript, we provid...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2010-04-01 00:00:00
abstract::The number of women who become ill and die from acute myocardial infarction (AMI) increases steadily with age. It is not yet clearly defined whether and why women suffer from a higher in-hospital mortality rate after AMI. In this study we evaluated the importance of the female sex as a risk factor for in-hospital mort...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:1997-06-01 00:00:00
abstract::The Impella left ventricular support system consists of two main components: a family of different ventricular support catheters with a microaxial pump to be placed across the aortic valve and a single external controller which is connected to activate and control the pump function. Four Impella left ventricular suppo...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4725.18.04703-5
更新日期:2018-10-01 00:00:00