Abstract：
:Inflammatory mechanisms play a pivotal role in the atherosclerotic process. At the base of atherogenesis there are complex interactions between macrophages, T lymphocytes and smooth muscle cells. A growing body of experimental evidences suggest that inflammation is involved in the pathogenesis of acute coronary syndromes (ACS) and influences their clinical evolution. In fact, in patients with ACS, coronary atherosclerotic plaques are characterized by an abundant inflammatory infiltrate. Moreover, in these patients systemic signs of inflammatory reaction can be observed: activated circulating inflammatory cells (neutrophil, monocytes and lymphocytes) and increased concentrations of pro-inflammatory cytokines, such as interleukin (IL)-1 and 6, and of acute phase reactants, in particular C-reactive protein (CRP). Recent data demonstrate that CRP is a strong independent predictor of adverse cardiac events and death in patients with ACS, but also in patients with stable ischemic heart disease and in apparently healthy men and women. Furthermore, CRP is an important prognostic index, for early and late outcome, in patients undergoing percutaneous coronary interventions, and may be useful in choosing the therapeutic management of the patient. Although the causes of inflammation in patients with ACS are not yet clear, this new line of research may open the way to a different clinical approach for these patients.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Biasucci LM,Santamaria M,Liuzzo Gkeywords:
subject
Has Abstractpub_date
2002-10-01 00:00:00pages
475-86issue
5eissn
0026-4725issn
1827-1618journal_volume
50pub_type
杂志文章abstract：BACKGROUND:Sutureless aortic valve prostheses have the potential to augment the adoption of alternative incision approaches for aortic valve replacement (AVR). Still, we lack the evidence on which surgical approach is best associated with sutureless AVR. METHODS:Data on 483 patients undergoing sutureless small incisio...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.17.04568-6
更新日期：2018-04-01 00:00:00
abstract：:Colchicine was introduced in 1987 for the treatment of recurrent pericarditis. Up to the present, papers have been published on a total of 117 patients treated with colchicine after the failure of treatment with FANS, corticosteroids and repeated pericardiocentesis. Here two cases of chronic pericardial effusion, one ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-10-01 00:00:00
abstract：:Some cases of coronary aneurysms studied echocardiographically in children suffering from Kawasaki's disease are reported. In the fourth case, bidimensional echocardiography highlighted a uniform dilatation of the right and left coronary proximal segments which had retreated at subsequent controls. In the third case, ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:The Authors describe a case of a patient showing, during an episode of chest pain, an ecg-pattern of wide and tall "Q" wave simulating inferior myocardial infarction. In fact, a further ecg recorded during sinus rhythm denotes that the "Q" wave was a retrograde P wave generated by a nodal rhythm. The other known cause...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：BACKGROUND:Aim of the present comparative clinical study was to demonstrate the efficacy of the topical application of mesoglycan, a profibrinolytic agent, for healing of leg ulcers in patients with chronic venous insufficiency. METHODS:Forty patients, observed in our outpatients department, with venous leg ulcers hav...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:In the period 1972-1988, 209 patients (81 males, 128 females, mean age 42.4 +/- 11.9, range 20-71 years) underwent surgery for multiple valve repair (MVR) at the Italian Institution of Cardiac Surgery. Ninety-five patients had previously undergone mitral commissurotomy (MC). NTHA function class was III-IV in 89% of th...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:Contrast enhanced computed tomography angiography (CTA) has seen rapid progress in its utility for the assessment of coronary artery disease (CAD) in the last few years. More and more technological enhancements have widened the horizons for the use of this non-invasive modality beyond its traditional role in assessmen...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：:Thrombophilia is characterised by elevated thrombotic and embolic risk and may be caused by congenital or acquired coagulating inhibitor deficit. A young man was repeatedly admitted to Emergency Medicine Units because of pain, oedema and slight functional impairment of the left leg, and recurrent thrombophlebitis was ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:To analyze the usefulness of autologous blood salvage and intraoperative isovolemic hemodilution in conjunction with autologous blood salvage in cardiac surgery, and also to compare two different autologous blood salvage methods. EXPERIMENTAL DESIGN:Retrospective analysis of transfusion practice in cardiac s...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：BACKGROUND:The aim of this study to investigate the correlation of the peripheral concentrations of one representative estrogen, E2 estradiol, with various indicators reflecting different aspects of cardiac structures and functions. METHODS:A total of 84 typical patients with hypertrophic cardiomyopathy (HCM) and 77 h...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2016-08-01 00:00:00
abstract：AIM:Studies on percutaneous transluminal cardiac angioplasty (PTCA) in patients with end stage renal disease (ESRD) on hemodialysis have suggested high rates of procedural complications and restenosis. Bare metal stent percutaneous coronary intervention (PCI) has significantly reduced restenosis and subsequent target l...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,meta分析,评审
doi：
更新日期：2009-06-01 00:00:00
abstract：:Fragments of synthetic prostheses in knitted Dacron velour implanted years previously have been examined. Macrophages were found which fragment elements of the prostheses. It is concluded that synthetic knitted velour prostheses are biodegradable. ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Hypertension remains a major public health burden despite the plethora of therapeutic agents available for this disorder, compelling innovation of alternate therapies including interventional approaches where necessary. The kidney is a major player in the pathophysiology of this disease with increased sympathetic acti...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2014-02-01 00:00:00
abstract：:The incidence of district (cardiac, cerebral, renal) and systemic vascular complications was studied in a population of 3992 hypertensive in-patients during the period from 1984 to 1988. The total number of male hypertensive patients was always higher (2355) than that of female hypertensive patients (1637). From the a...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：BACKGROUND:Unstable angina implies high risk of myocardial infarction and sudden death. Increased levels of cytoplasmatic enzymes and proteins (creatine phosphokinase, MB creatine phosphokinase troponin T, etc.) were described in unstable angina, providing information about incoming major coronary events. Cardiac tropo...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:The authors present the results of a research on 3,888 patients (1,768 males and 2,120 females) admitted to the 1st Internal Medicine Department of Leghorn Hospital during two years (from July 1993 to June 1995). The research is intended to value the hyperlipidaemia's incidence in hospitalized patients, and the associ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Use of definite molecular weight heparan sulphate in a protocol for the prevention of deep venous thrombosis in the total joint replacement surgery. The authors propose a working protocol for the prevention of deep venous thrombosis in prosthetic orthopaedic surgery. It requires that integration of pharmacological, an...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:The role of routine intravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) in the bare metal stent era remains controversial. The potential to reduce revascularization was reported without impacting non-fatal myocardial infarction and death. Drug-eluting stents (DES) have realized imp...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2008-02-01 00:00:00
abstract：:Myocardial infarction in the under-40s is rare. A series of 19 patients, 3.07% of a two-year series of coronary cases, is presented with a view to evaluating the incidence of risk factors, with special attention to familial factors and dyslipoproteinaemia. Risk factors are discussed together with the statistical impor...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:The meaning of the term biomarker has been standardized by a working group of the National Institutes of Health as "a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention". The ability of...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
abstract：:Coronary artery disease among women presents differences in terms of clinical presentation and pathophysiology. To date, women present worse prognoses with more events and higher mortality rate. One the one hand, they are less likely addressed for invasive therapy. One the other hand, revascularization procedures, whe...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.20.05203-2
更新日期：2020-10-01 00:00:00
abstract：AIM:The aim of this study was to evaluate the effects of low-dose niacin extended-release (niacin-ER) combined with simvastatin (SV) in the treatment of patients with mixed dyslipidemia who have not normalized their lipid profile with statin therapy alone. METHODS:A prospective, clinical trial of 35 patients with mixe...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：2010-10-01 00:00:00
abstract：:We report the case of an 80-year-old man affected by hypertensive cardiomyopathy and already admitted to our Division for recurrent episodes of heart failure. He was eventually hospitalized for septic shock secondary to disseminated pneumonia with concomitant left pleural effusion. At 2D-echo examination, a highly ech...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：:Pathophysiological remodeling of cardiac function occurs at multiple levels, spanning the spectrum from molecular and sub-cellular changes to those occurring at the organ-system levels. Of key importance to arrhythmias are changes in the electrophysiological substrate at the tissue level. In this manuscript, we provid...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2010-04-01 00:00:00
abstract：:Although drug-eluting stents (DES) have significantly reduced the rates of restenosis as compared to bare metal stents, late stent thrombosis remains a major drawback, especially for "off-label" use. Delayed arterial healing, characterized by persistent fibrin deposition and poor endothelialization, has been shown to ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2012-02-01 00:00:00
abstract：AIM:Coronary artery disease (CAD) is a leading cause of morbidity and mortality in the developed world and is rapidly assuming epidemic proportions in developing countries, including India. Extensive research has proven the role of multiple etiologies such as dyslipidemia, inflammation, endothelial dysfunction and insu...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Among the acute effects of cigarette smoking there are an increase in the arterial blood pressure and a decrease in skin temperature. The aim of this study is to evaluate whether these effects are more evident in hypertensive subjects (HTS) than in normotensive (NTS) ones. METHODS:A monitored Ambulatory Blo...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：:After recalling that cardiovascular complications represent the most frequent cause of mortality and morbidity in hypertensive patients, the author describes the main mechanism responsible for increased plasma level concentrations of Angiotensin in this syndrome. He subsequently illustrates the effects of ACE-inhibito...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2001-10-01 00:00:00
abstract：:Hypertrophic cardiomyopathy (HCM) occurs in 1 in every 500 individuals. It represents the most common cause of sudden cardiac death in those under the age of twenty-five. 3-5% patients with HCM go on to develop the dilated, hypokinetic end stage (ES) HCM with systolic failure. They have a higher incidence of heart fai...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:The proposal of this study is to compare the efficacy of lisinopril and theophylline, alone or in association, on erythrocytosis in renal-transplanted patients. DESIGN:Prospectic, case-control study. PATIENTS/ENVIRONMENT: 15 inpatients meeting 3 main criteria: 1) ACE therapy for past erythrocytosis, 2) actua...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章,评审
doi：
更新日期：1997-11-01 00:00:00
