Abstract:
BACKGROUND:The aim of this study to investigate the correlation of the peripheral concentrations of one representative estrogen, E2 estradiol, with various indicators reflecting different aspects of cardiac structures and functions. METHODS:A total of 84 typical patients with hypertrophic cardiomyopathy (HCM) and 77 healthy subjects were enrolled. Venous blood samples were taken to test E2 estradiol contents. Echocardiographic imaging was performed to record various indices of cardiac structures and functions. RESULTS:Concentrations of peripheral E2 estradiol were decreased in female HCM patients, compared to female normal controls; after medical treatment, peripheral E2 estradiol levels were elevated, nearly to normal levels. Peripheral E2 estradiol concentrations were negatively correlated with LAV (r2=0.5078, P<0.001), LAVI (r2=0.4257, P<0.001), E/A ratio (r2=0.4328, P=0.006) and E/Ea ratio (r2=0.4393, P<0.001) in female controls and patients. CONCLUSIONS:Concentrations of peripheral E2 estradiol were negatively correlated with ventricular diastolic functions and this correlation was gender-dependent. Our study could provide clues to explore the molecular mechanisms of HCM, and clinic evidence for the diagnosis and prognostic management of HCM patients, as well as medical intervening for HCM.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Tan B,Zhao L,FaweiHE Fsubject
Has Abstractpub_date
2016-08-01 00:00:00pages
383-90issue
4eissn
0026-4725issn
1827-1618pii
R05Y9999N00A140065journal_volume
64pub_type
杂志文章abstract::The Authors describe a case of uniatrial univentricular heart with a right transposition and atresia of the aorta. This case forms part of an autoptic series of 74 congenital cardiopathies with defects of the septal system: monometameric (52 cases), polymetameric (22 cases), and limited (66 cases) or broad DIA, DIV or...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.17.04535-2
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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更新日期:2002-12-01 00:00:00
abstract::We report the case of an 80-year-old man affected by hypertensive cardiomyopathy and already admitted to our Division for recurrent episodes of heart failure. He was eventually hospitalized for septic shock secondary to disseminated pneumonia with concomitant left pleural effusion. At 2D-echo examination, a highly ech...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
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abstract::Non-invasive imaging plays an increasingly important role in the diagnosis and risk stratification of coronary artery disease (CAD). Several techniques such as stress echocardiography and myocardial perfusion imaging have become available to assess cardiac function and myocardial perfusion. With the arrival of multi-s...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2008-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
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journal_title:Minerva cardioangiologica
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更新日期:1989-07-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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更新日期:2013-06-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
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更新日期:1997-06-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
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doi:
更新日期:2016-12-01 00:00:00
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更新日期:2017-10-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2012-04-01 00:00:00
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journal_title:Minerva cardioangiologica
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doi:
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journal_title:Minerva cardioangiologica
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journal_title:Minerva cardioangiologica
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doi:
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.16.04278-X
更新日期:2017-06-01 00:00:00
abstract::Bacterial endocarditis in pregnancy is uncommon. We described two cases: the first case of endocarditis, caused by staphylococcus epidermidis (at the 35th week of pregnancy) was complicated by severe aortic valvular insufficiency; the second case, endocarditis caused by streptococcus alpha hemolytic (at the 32nd week ...
journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05288-3
更新日期:2020-06-10 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 临床试验,杂志文章
doi:
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