Abstract：
:Coronary artery disease among women presents differences in terms of clinical presentation and pathophysiology. To date, women present worse prognoses with more events and higher mortality rate. One the one hand, they are less likely addressed for invasive therapy. One the other hand, revascularization procedures, whether by bypass or by percutaneous coronary intervention, are associated with higher rates of complications and poorer prognosis. Despite higher risk factor burden and comorbidity, women are less affected by obstructive disease and plaque characteristics are more favorable than among men. Abnormalities of endothelial function and micro vascular flow reserve could explain part of the high prevalence of symptoms of angina observed among women. Due to the worse prognosis of microvascular dysfunction, particularly in women, proper diagnosis is mandatory and deserve invasive management. Outcome following ST elevation myocardial infarction is still more severe among women with higher in-hospital mortality, but sex discrepancies are observed even in elective percutaneous coronary intervention. However, improvement of techniques, drugs and devices benefited to both men and women and tend to decrease gender gap. Especially, changes in the design of newer-generation drug-eluting stents (DES) may be particularly important for women. Female sex remains a potent predictor of higher risk of bleeding and vascular complication; thus important efforts should be promoted to develop bleeding avoidance strategies. Sex-based differences still deserve dedicated investigations in terms of physiopathology, particular hormonal impacts, and specific responses to drugs and devices.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Manzo-Silberman Sdoi
10.23736/S0026-4725.20.05203-2subject
Has Abstractpub_date
2020-10-01 00:00:00pages
393-404issue
5eissn
0026-4725issn
1827-1618pii
S0026-4725.20.05203-2journal_volume
68pub_type
杂志文章abstract：:After the introduction of coronary balloon angioplasty, bare-metal, and drug-eluting stents, fully bioresorbable scaffolds (BRS) could be the fourth revolution in interventional cardiology. The BRS technology shares the advantages of metallic stents regarding acute gain and prevention of acute vessel occlusion by prov...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-04-01 00:00:00
abstract：:The carotid artery is one of the most important sites in the progression of atherosclerotic lesions. Atherosclerosis is known to be determined by a variety of factors, among which arterial hypertension is one of the most important. Blood pressure control by antihypertensive treatment is thus of great benefit in manage...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:The metabolic abnormalities associated with diabetes mellitus result in macrovascular and microvascular complications in multiple organ systems; it is the cardiovascular impact that accounts for the greatest morbidity and mortality associated with this disease. Heart failure, both with reduced and preserved systolic f...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2004-12-01 00:00:00
abstract：:In obesity, the systemic resistances (SR) are reduced while the blood volume is increased. The rise of cardiac output (CO), stress-induced, produces an increase in blood pressure (BP), as an hypertensive behavior of the stress-response. The aim of our study is to evaluate if, in obese subjects, the considerable increa...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:Brief periods of non-lethal ischemia and reperfusion render the myocardium more resistant to subsequent ischemia. This adaption occurs in a biphasic pattern: the first being active immediately and lasting for 2-3 hrs (early preconditioning), the second starting at 24 hrs until 72 hrs after the initial ischemia (delaye...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2002-12-01 00:00:00
abstract：:In presence of a patent foramen ovale (PFO) with cryptogenic cerebral embolism, traditional therapy consists of oral anticoagulation or antiplatelet therapy. Surgery was considered only in case of recurrence. Transcatheter closure of PFO is currently performed. The availability of new user friendly devices and the inc...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:The deep femoral artery provides the primary blood supply to the thigh, and in addition serves as the major collateral channel for bypassing the obstructed superficial femoral artery. The purpose of isolated profundoplasty is to relieve a significant stenosis and improve perfusion of the ischaemic leg. METH...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
abstract：:Aneurysms are a later consequence of acute myocardial infarction, developing in about 20% of patients with transmural infarcts. Pathologically aneurysms have two general forms: the first type has large endocardial fibroelastosis overlying the infarct size, the second type contains little or no endocardial fibroelastos...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:Radial approach has been used since 1989 to perform coronary angiography as an alternative to femoral access. During past decades, the development of dedicated equipment has led to high efficacy also in complex procedures. ST elevation myocardial infarction (STEMI) is known to be a high bleeding risk setting and in tu...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2016-06-01 00:00:00
abstract：:Colchicine was introduced in 1987 for the treatment of recurrent pericarditis. Up to the present, papers have been published on a total of 117 patients treated with colchicine after the failure of treatment with FANS, corticosteroids and repeated pericardiocentesis. Here two cases of chronic pericardial effusion, one ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2000-10-01 00:00:00
abstract：:Some cases of coronary aneurysms studied echocardiographically in children suffering from Kawasaki's disease are reported. In the fourth case, bidimensional echocardiography highlighted a uniform dilatation of the right and left coronary proximal segments which had retreated at subsequent controls. In the third case, ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:Torsade de pointes is a form of polymorphous ventricular tachycardia in which the polarity of the QRS complex exhibits phasic alterations in both axis. Traditionally, torsade de pointes has been described in association with a congenital or acquired (including drug and metabolic) causes of QT prolongation. Clinical ou...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:Clopidogrel is an oral tyenopiridin with a central role in the management of acute coronary syndromes and after stent implantation. Despite the use of this drug, many patients continue to experience thrombotic events which are usually referred as "therapy failure". Actually, to date, only stent thrombosis is considere...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2013-12-01 00:00:00
abstract：:The authors report a 57 year old patient affected by rhinopharyngeal NH lymphoma that appeared as a parapharyngeal space lesions-syncope syndrome. The activation of a cardioinhybitory reflex by the stimulation of the glossopharyngeal nerve seems to be the pathogenetic basis for his syndrome. ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUD:This study aimed to analyze the correlations between anterior wall motion velocity of ascending aorta measured by quantitative tissue velocity image (QTVI) technique and left ventricular geometry as well as left heart function to evaluate its value of clinical application. METHODS:One hundred ten hypertensio...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.17.04535-2
更新日期：2018-04-01 00:00:00
abstract：:The transradial access (TRA) for cardiac catheterization and percutaneous coronary intervention (PCI) has been widely adopted in the last decades since its first description in the late forties. The transradial approach has been associated with favourable outcomes as compared with transfemoral access (TFA) in several ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.20.05391-8
更新日期：2020-11-04 00:00:00
abstract：:Inflammation is an important contributor to atherothrombosis. The C-reactive protein (CRP) is not only an excellent biomarker of inflammation, but it is also a direct participant in atherogenesis. CRP consistently predicts new coronary events, including myocardial infarction and death, in patients with ischemic heart ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2005-02-01 00:00:00
abstract：:Left main coronary artery (LMCA) disease has been reported in up to 10% of all patients with coronary artery disease (CAD) and in the majority of cases are associated with severe three-vessel CAD. Among patients with chronic coronary syndrome revascularization of significant LMCA disease improves prognosis, while ther...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：10.23736/S0026-4725.20.05198-1
更新日期：2020-10-01 00:00:00
abstract：:The clinical significance of coronary myocardial bridging has been debated and different interventional strategies proposed. We discuss the case of a patient who presented with the recent onset of symptoms of exertional chest pain, diaphoresis, and electrocardiographic signs of acute anterior myocardial wall ischemia....
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:A comparative analysis of arrhythmias by "basal" electrocardiogram (ECG) and by continuous 24-hour Holter electrocardiogram monitoring was performed in 17 patients with systemic sclerosis (16 women and one man). Our study confirms that rhythm disturbances are better detectable using Holter monitoring. In fact, no pati...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：:The clinical introduction of catheter ablation in 1981 revolutionized the treatment of cardiac arrhythmias. Implementation of radiofrequency as an alternative energy source, with the advantages of higher selectivity and less collateral damage, provided an expansion of catheter ablation therapy. Today the majority of a...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2002-06-01 00:00:00
abstract：:Pulmonary hypertension (PH) is the common hemodynamic consequence of various pathophysiologic mechanisms. Since the publication of the most current American and European guidelines (2009) new agents were introduced into the clinical arena while data regarding former drugs has been substantiated. The therapeutic endeav...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-01 00:00:00
abstract：AIM:To evaluate any differences in ventricular pre-excitation secondary to Wolff Parkinson White syndrome in the aged compared to young and adult patients. METHODS: EXPERIMENTAL DESIGN:a clinical study was performed using a comparative prospective criterion with retrospective analysis. The duration of follow-up range...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:The presence of high-risk features on candidates to percutaneous revascularization is increasingly leading to Impella®-assisted procedures (IAPs). While IAPs are safe and effective procedures, they still require managing a degree of complexity. Clinicians often rely on their ability to recall every step of operative p...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4725.18.04669-8
更新日期：2018-10-01 00:00:00
abstract：:Intraoperative transesophageal echocardiography (IOTEE) has become an important diagnostic and monitoring tool in the operating theatre during cardiac and noncardiac operations. However, its routine application during valve replacement operations has not received universal recognition. The cumulative experience, broug...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2007-04-01 00:00:00
abstract：:The definition of an ischaemic condition at lower limb level, may imply any different degree of the pathology, starting from a simple chronic slight claudication up to a severe ischaemia. Critical Limb Ischaemia is the term defined to identify an ischaemic condition, which endangers the limb or part of a limb and requ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:The development of drug-eluting stents is one of the major revolutions in the field of Interventional Cardiology. Restenosis rate has been significantly reduced, in comparison to bare metal stents. The ideal drug to prevent restenosis must have an anti-proliferative and anti-migratory effect on smooth muscle cells but...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:Aim of the present comparative clinical study was to demonstrate the efficacy of the topical application of mesoglycan, a profibrinolytic agent, for healing of leg ulcers in patients with chronic venous insufficiency. METHODS:Forty patients, observed in our outpatients department, with venous leg ulcers hav...
journal_title：Minerva cardioangiologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:An evaluation of the effects of statins on total mortality in the context of primary prevention was carried out, by means of the analysis of data taken from major clinical trials published in the literature. EVIDENCE ACQUISITION:Published systematic reviews were used to identify relevant clinical trials, ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,meta分析,评审
doi：10.23736/S0026-4725.17.04323-7
更新日期：2017-10-01 00:00:00
abstract：:This study is aimed at analyzing our experience in the evolution of aneurysmatic disease after surgical treatment of the typical subrenal abdominal aortic aneurysm. In fact in some cases we reobserved these patients for the onset of a new important dilatation involving the proximal tract of the abdominal aorta or the ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
