Abstract:
:The association between portal venous hypertension and pulmonary arterial hypertension has received scarce attention in the italian medical literature. Nevertheless the association is relatively frequent, it needs a multidisciplinary approach and it is a stimulus for the search of causes of so-called primary pulmonary hypertension. The purpose of the article is to review the frequency of the association, the main pathogenetic hypothesis formulated to explain the appearance of pulmonary hypertension, the clinical and the laboratory findings, the evolution of the association and to present briefly a personal series of cases. The pulmonary arterial hypertension has been found in approximately 2% of patients with portal hypertension due to either hepatic cirrhosis or extraepatic lesions. Microembolism from the portocavat system or a number of vasoactive substances which enter the pulmonary circulation without being inactivated by the liver have been held responsible for the appearance of pulmonary hypertension in predisposed patients. Clinical and laboratory findings do not differ from those a patients with primary pulmonary hypertension. Also the prognosis is similar. In conclusion on accurate examination of the pulmonary circulation by noninvasive methods, in particular by echocardiography, appears to be mandatory in patients with chronic hepatic lesions. When pulmonary arterial hypertension is detected the study of the biochemical factors which at present are known to determine pulmonary hypertension may be warranted. The study may enhance our knowledge of the pathogenesis of the so-called primary pulmonary hypertension.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Arcangeli C,Squillantini G,Santoro G,Marioni C,Forte P,Chibbaro G,Dolara Asubject
Has Abstractpub_date
1996-07-01 00:00:00pages
343-52issue
7-8eissn
0026-4725issn
1827-1618journal_volume
44pub_type
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journal_title:Minerva cardioangiologica
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journal_title:Minerva cardioangiologica
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journal_title:Minerva cardioangiologica
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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更新日期:1991-03-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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更新日期:1991-01-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-02-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:10.23736/S0026-4725.20.05391-8
更新日期:2020-11-04 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-10-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2002-06-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.23736/S0026-4725.17.04535-2
更新日期:2018-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-08-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2012-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
doi:
更新日期:2003-06-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
doi:
更新日期:2006-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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更新日期:2005-02-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章,评审
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更新日期:2009-04-01 00:00:00
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journal_title:Minerva cardioangiologica
pub_type: 杂志文章
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更新日期:2001-12-01 00:00:00
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更新日期:2004-04-01 00:00:00