Induction of male-type gonadotropin secretion by implantation of 11-ketotestosterone in female goldfish.


:In goldfish, plasma gonadotropin levels increase during spawning in both males and females (GTH surge). A female-typical GTH surge induces ovulation (ovulatory surge), and a male-typical surge triggers milt production in response to sex pheromones released from ovulatory females. This study examined whether the male-typical GTH surge occurs in adult females that are implanted with 11-ketotestosterone (KT), which induces male-typical sexual behavior in adult female goldfish. When KT-implanted females were exposed to ovulatory females, a GTH surge occurred without ovulation. No GTH surge was observed when KT-females were exposed to nonovulatory females. The GTH secretion in KT-females was further characterized by exposure to 17alpha,20beta-dihydroxy-4-pregnen-3-one (17,20-P), a female sex pheromone that induces the GTH surge in males. Exposure to waterborne 17,20-P caused an elevation of GTH levels in KT-females as well as in males. The elevation of GTH levels induced by 17,20-P exposure was abolished when the KT-females were rendered anosmic. Unlike the female-typical ovulatory GTH surge that occurs in synchrony with photoperiod and peaks in the dark phase of the day, the 17,20-P-induced surge did not show a peak in the dark phase. These results indicate that the GTH surge in KT-females is a male-typical surge. Together with a previous study showing KT-induced behavioral masculinization (N. E. Stacey and M. Kobayashi, 1996, Horm. Behav. 30, 434-445), this adult gonochoristic species was shown to possess sexual plasticity of brain function in behavior and GTH secretion in response to sex steroid.


Gen Comp Endocrinol


Kobayashi M,Furukawa K,Kim MH,Aida K




Has Abstract


1997-12-01 00:00:00














  • Validation of an enzyme-immunoassay for the non-invasive monitoring of faecal testosterone metabolites in male cheetahs (Acinonyx jubatus).

    abstract::In mammals, the sex hormone testosterone is the major endocrine variable to objectify testicular activity and thus reproductive function in males. Testosterone is involved in the development and function of male reproductive physiology and sex-related behaviour. The development of a reliable androgen enzyme-immunoassa...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Pribbenow S,Wachter B,Ludwig C,Weigold A,Dehnhard M

    更新日期:2016-03-01 00:00:00

  • Overexpression of Drosophila juvenile hormone esterase binding protein results in anti-JH effects and reduced pheromone abundance.

    abstract::The titer of juvenile hormone (JH), which has wide ranging physiological effects in insects, is regulated in part by JH esterase (JHE). We show that overexpression in Drosophila melanogaster of the JHE binding protein, DmP29 results in a series of apparent anti-JH effects. We hypothesize that DmP29 functions in transp...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Liu Z,Li X,Prasifka JR,Jurenka R,Bonning BC

    更新日期:2008-03-01 00:00:00

  • Variations in plasma corticosterone, estrone, estradiol-17 beta, and progesterone concentrations with forced renesting, molt, and body weight of captive female American kestrels.

    abstract::Corticosterone, progesterone, estradiol-17 beta, and estrone were quantified in plasma collected weekly (April-September) from renesting and nonlaying female American kestrels (Falco sparverius) paired with males in captivity. Hormone levels and body weights for laying females were maximal during courtship and egg-lay...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Rehder NB,Bird DM,Laguë PC

    更新日期:1986-06-01 00:00:00

  • Application of sensitive enzymeimmunoassay for determination of testosterone in blood plasma of yaks (Poephagus grunniens L.).

    abstract::As an alternative to radioimmunoassays, a simple, highly sensitive and quick enzymeimmunoassay (EIA) for determination of testosterone in blood plasma of yaks on microtitreplates using second antibody coating technique and testosterone-horseradish peroxidase as a label has been developed for the first time. The wells ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Sarkar M,Dutta Borah BK,Meyer HH,Prakash BS

    更新日期:2008-09-15 00:00:00

  • Role of thyroid and testicular hormones in the regulation of basal metabolic rate, gonad development, and body weight of spotted munia, Lonchura punctulata.

    abstract::Normal saline, L-thyroxine (L-T4, 0.5 micrograms/bird/day), and testosterone (100 micrograms/bird/day) were administered separately to intact, thyroidectomized, and castrated spotted munia over a 30-day period and the effects on basal metabolic rate (BMR), gonads, and body weight were recorded. Thyroidectomy and castr...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Gupta BB,Thapliyal JP

    更新日期:1984-10-01 00:00:00

  • The causative effects of corticosterone on innate immunity during the stress response in the House Sparrow, Passer domesticus.

    abstract::Stress-induced inhibition of innate immune activity has been observed in a variety of wild birds and may increase chances of infection because this activity constitutes the first line of defense against pathogens. We previously reported that the transient elevation of plasma corticosterone (CORT; the primary avian glu...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Gao S,Deviche PJ

    更新日期:2019-05-01 00:00:00

  • Corticosterone levels during post-natal development in captive American kestrels (Falco sparverius).

    abstract::We investigated post-natal development of the adrenocortical stress-response system in captive American kestrels (Falco sparverius) by measurements of baseline and stress-induced levels of corticosterone at ages 10, 16, 22, and 28 days post-hatching. Baseline levels of corticosterone increased significantly during pos...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Love OP,Bird DM,Shutt LJ

    更新日期:2003-02-01 00:00:00

  • Testosterone control of territorial behavior: tonic-release implants fully restore seasonal and short-term aggressive responses in free-living castrated lizards.

    abstract::Two aspects of hormonal control of aggressive territorial behavior in male mountain spiny lizards Sceloporus jarrovi were studied. First, testosterone (T) implants were given to free-living castrated males during the breeding season. These implants fully restored breeding season levels of aggressive and sexual behavio...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Moore MC

    更新日期:1988-06-01 00:00:00

  • Differential expression of estrogen receptor alpha in the embryonic adrenal-kidney-gonadal complex of the oviparous lizard, Calotes versicolor (Daud.).

    abstract::Estrogen signalling is critical for ovarian differentiation in reptiles with temperature-dependent sex determination (TSD). To elucidate the involvement of estrogen in this process, adrenal-kidney-gonadal (AKG) expression of estrogen receptor (ERα) was studied at female-producing temperature (FPT) in the developing em...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Inamdar LS,Khodnapur BS,Nindi RS,Dasari S,Seshagiri PB

    更新日期:2015-09-01 00:00:00

  • Immunoreactive salmon calcitonin-like molecule in crustaceans: high concentrations in Nephrops norvegicus.

    abstract::A salmon calcitonin (CT)-like peptide was characterized in various crustaceans by radioimmunological and radioreceptor assays. The highest levels of the molecule were found in the anterior part of the gut and the hepatopancreas of the Norway lobster: Nephrops norvegicus. Molecular sieving of this molecule suggested an...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Fouchereau-Peron M,Arlot-Bonnemains Y,Milhaud G,Moukhtar MS

    更新日期:1987-02-01 00:00:00

  • Yolk testosterone levels and dietary carotenoids influence growth and immunity of grey partridge chicks.

    abstract::Early maternal effects in the form of substances accumulated in the egg, such as carotenoids and hormones, can be physiologically relevant for a good development of offspring. It has been found in different species that testosterone (T) can be beneficial to offspring by increasing growth rate, but detrimental by reduc...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Cucco M,Guasco B,Malacarne G,Ottonelli R,Tanvez A

    更新日期:2008-04-01 00:00:00

  • Characterization of an estrogen receptor in the turtle testis.

    abstract::Using DNA-cellulose affinity chromatography, an estrogen-binding component having the properties of a classical estrogen receptor was characterized from testicular cytosol of the freshwater turtle, Chrysemys picta. This putative cytoplasmic receptor exhibited high affinity (Kd = 7.0 X 10(-10) M), low capacity (1-4 fmo...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Mak P,Ho SM,Callard IP

    更新日期:1983-11-01 00:00:00

  • Vitellogenin of Fujian oyster, Crassostrea angulata: Synthesized in the ovary and controlled by estradiol-17β.

    abstract::In this study, we cloned a full-length cDNA encoding vitellogenin (Vg) in the Fujian oyster Crassostrea angulata. The complete Vg cDNA consists of 5160 nucleotides with a long open reading frame encoding 1641 amino acid residues. The deduced amino acid sequence shared high similarity with the Vgs of other mollusc, fis...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Ni J,Zeng Z,Kong D,Hou L,Huang H,Ke C

    更新日期:2014-06-01 00:00:00

  • The effects of cortisol on hepatocyte metabolism in rainbow trout: a study using the steroid analogue RU486.

    abstract::The objective of this study was to examine if RU486, a corticosteroid antagonist, modified hepatocyte metabolism and blocked the metabolic effects of exogenously administered cortisol in rainbow trout (Oncorhynchus mykiss). The fish were given a single intraperitoneal implant of either coconut oil alone or coconut oil...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Vijayan MM,Reddy PK,Leatherland JF,Moon TW

    更新日期:1994-10-01 00:00:00

  • Evolution of insulin-like growth factor (IGF) function: production and characterization of recombinant hagfish IGF.

    abstract::While there is considerable structural evidence that insulin-like growth factors (IGFs) share a long evolutionary history, little is known about the conservation of IGF function. In order to address this, we have made recombinant hagfish IGF, hence allowing characterization of an IGF from a representative of the primi...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Upton Z,Francis GL,Chan SJ,Steiner DF,Wallace JC,Ballard FJ

    更新日期:1997-01-01 00:00:00

  • Coping with pregnancy after 9months in the dark: Post-hibernation buffering of high maternal stress in arctic ground squirrels.

    abstract::Pregnancy and lactation are key times in the life of female mammals when energetic resources must be brought to bear to produce and nurture offspring. Changes in glucocorticoid (GC) levels are central to this objective, due to their roles in modulating development and physiology and in mediating energetic tradeoffs. W...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Edwards PD,Boonstra R

    更新日期:2016-06-01 00:00:00

  • Locust diuretic hormone-stimulated synthesis and excretion of cyclic-AMP: a novel Malpighian tubule bioassay.

    abstract::Endogenous cyclic-AMP concentrations in Malpighian tubules of locusts increase as a result of diuretic hormone stimulation, and the level of increase is shown to be dependent on basal intracellular levels of cyclic-AMP. Furthermore, the increase in endogenous cyclic-AMP is in such excess as to cause excretion of high ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Rafaeli A,Pines M,Stern PS,Applebaum SW

    更新日期:1984-04-01 00:00:00

  • The role of the hypothalamus-pituitary-adrenal/interrenal axis in mediating predator-avoidance trade-offs.

    abstract::Maintaining energy balance and reproducing are important for fitness, yet animals have evolved mechanisms by which the hypothalamus-pituitary-adrenal/interrenal (HPA/HPI) axis can shut these activities off. While HPA/HPI axis inhibition of feeding and reproduction may have evolved as a predator defense, to date there ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Harris BN,Carr JA

    更新日期:2016-05-01 00:00:00

  • Catecholamine effects on blood pressure and heart rate in warm- and cold-acclimated American bullfrogs (Rana catesbeiana).

    abstract::The effects of epinephrine (E), norepinephrine (NE), phenylephrine (PHE), and isoproterenol (ISO) were studied in vivo on the blood pressure and heart rate of the conscious American bullfrog, Rana catesbeiana. Bullfrogs were chronically cannulated with a T cannula in the right sciatic artery. In warm-acclimated (22 de...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Herman CA,Mata PL

    更新日期:1985-09-01 00:00:00

  • Hormonal regulation of ion and water transport in anuran amphibians.

    abstract::Amphibians occupy a wide variety of ecological habitats, and their adaptation is made possible through the specialization of the epithelia of their osmoregulatory organs, such as the skin, kidney, and urinary bladder, which control the hydromineral and acid-base balance of their internal medium. Amphibians can change ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Uchiyama M,Konno N

    更新日期:2006-05-15 00:00:00

  • Interaction of surgical deafening and photoperiod on cloacal gland and testes size in Japanese quail.

    abstract::Two experiments were conducted to further examine the interaction of social stimuli and photoperiod on cloacal and gonadal responses in male Japanese quail. In experiment 1, adult males kept on a maximal (15L:9D) stimulatory photoperiod were surgically deafened and/or visually isolated from roommates. After 6 weeks, t...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kerlan JT,Blumenthal DC,Gilsdorf JT,Greenspon JM

    更新日期:1988-03-01 00:00:00

  • Endocrine patterns associated with reproduction in the Nile hippopotamus (Hippopotamus amphibius) as assessed by fecal progestagen analysis.

    abstract::The hippopotamus (Hippopotamus amphibius) is a popular zoo animal and an integral part of wetland ecosystems in its native continent of Africa. However, information about the reproductive physiology of the hippopotamus is limited compared to the other megaherbivores of Africa such as the elephant and the rhinoceros. T...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Graham LH,Reid K,Webster T,Richards M,Joseph S

    更新日期:2002-08-01 00:00:00

  • Transcriptional signature of progesterone in the fathead minnow ovary (Pimephales promelas).

    abstract::A growing number of studies have examined transcriptional responses to sex steroids along the hypothalamic-pituitary-gonadal axis in teleost fishes. However, data are lacking on the molecular cascades that underlie progesterone signaling. The objective of this study was to characterize the transcriptional response in ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Garcia-Reyero N,Martyniuk CJ,Kroll KJ,Escalon BL,Spade DJ,Denslow ND

    更新日期:2013-10-01 00:00:00

  • Catecholamines, opioid peptides, and true opiates in the chromaffin cells of the eel: immunohistochemical evidence.

    abstract::An immunohistological analysis of the chromaffin cell system of the American eel revealed the presence of tyrosine hydroxylase (TH) and dopamine-beta-hydroxylase (DBH) in all cells. However, phenylethanolamine-N-methyltransferase (PNMT) was seen only in a fraction of the chromaffin cells. This suggests the presence of...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Hathaway CB,Epple A

    更新日期:1990-09-01 00:00:00

  • Production of symmetrical flatfish by controlling the timing of thyroid hormone treatment in spotted halibut Verasper variegatus.

    abstract::The thyroid hormone plays an essential role in the metamorphosis in flatfish, during which external asymmetry (for example, eye relocation and pigmentation) is established. However, no information is available on the expression mechanisms of metamorphic asymmetry. Since the presence of malformed juveniles (having eith...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Tagawa M,Aritaki M

    更新日期:2005-04-01 00:00:00

  • Glucagon- and NPY-related peptide-immunoreactive cells in the gut of sea bass (Dicentrarchus labrax L.): a light and electron microscopic study.

    abstract::Glucagon and peptide of the neuropeptide Y (NPY) family immunoreactivities were studied in the gut of sea bass (Dicentrarchus labrax) using antisera against bovine/porcine glucagon, porcine glucagon, glicentin (10-30), bovine pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), salmon PYY (sPYY), and NPY. Glu...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Gómez-visus I,García-Hernández MP,Lozano MT,Agulleiro B

    更新日期:1998-10-01 00:00:00

  • New insights into the signaling system and function of insulin in fish.

    abstract::Fish have provided essential information about the structure, biosynthesis, evolution, and function of insulin (INS) as well as about the structure, evolution, and mechanism of action of insulin receptors (IR). INS, insulin-like growth factor (IGF)-1, and IGF-2 share a common ancestor; INS and a single IGF occur in Ag...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Caruso MA,Sheridan MA

    更新日期:2011-09-01 00:00:00

  • Immunocytochemical and histological differences in the interrenal axis of feral brown trout, Salmo trutta, in metal-contaminated waters.

    abstract::There are more CRH-like immunoreactive neurons in the preoptic nucleus and nucleus lateralis tuberis in the brain of feral brown trout, Salmo trutta, living in cadmium- and zinc-contaminated regions of the Eagle River than in fish from an uncontaminated control site. Histological analyses revealed that interrenal cell...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Norris DO,Felt SB,Woodling JD,Dores RM

    更新日期:1997-12-01 00:00:00

  • Influence of potassium thiocyanate on thyroid function of rainbow trout, Salmo gairdneri.

    abstract::Sublethal doses of potassium thiocyanate (KSCN), an iodide competitor, depressed thyroidal radioiodide uptake of fed laboratory rainbow trout at 11 degrees, but did not depress either plasma levels of T4 (L-thyroxine) and T3 (triiodo-L-thyronine) or radioiodide incorporation into plasma iodothyronines. Furthermore, pl...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Eales JG,Shostak S

    更新日期:1983-07-01 00:00:00

  • Characterization of channel catfish (Ictalurus punctatus) melanocortin-3 receptor reveals a potential network in regulation of energy homeostasis.

    abstract::The melanocortin-3 receptor (MC3R) is known to be involved in regulation of energy homeostasis, regulating feed efficiency and nutrient partitioning in mammals. Its physiological roles in non-mammalian vertebrates, especially economically important aquaculture species, are not well understood. Channel catfish (Ictalur...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Yang LK,Zhang ZR,Wen HS,Tao YX

    更新日期:2019-06-01 00:00:00