Abstract：
:Present work was undertaken to ascertain the hepatoprotective effect of Swertia chirata in albino rats. Intraperitoneal injection of CCl4 (1 ml/kg body wt on every 72 hr. for 16 days) significantly increased serum aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), and alkaline phosphatase (ALP) activities and bilirubin level in rat, but liver glycogen and serum cholesterol levels were decreased. Histologically it produced hepatocytic necrosis especially in the centrilobular region. Simultaneous treatments with S. Chirata (in different doses, viz, 20, 50 and 100 mg/kg body wt daily) and CCl4 (similar dose to that mentioned earlier) caused improvement at both biochemical and histopathological parameters compared to that of CCl4 treatment alone but it was most effective when S. chirata was administered in a moderate dose (50 mg/kg body wt).
journal_name
Indian J Exp Bioljournal_title
Indian journal of experimental biologyauthors
Mukherjee S,Sur A,Maiti BRsubject
Has Abstractpub_date
1997-04-01 00:00:00pages
384-8issue
4eissn
0019-5189issn
0975-1009journal_volume
35pub_type
杂志文章abstract：:An originally isolated baculovirus, Spodoptera litura multiple nucleopolyhedrovirus (SpltMNPV) was serially passed through the S. litura larvae for upto four generations to determine the mean number of occlusion bodies (OBs) harvested per larva and their efficacy in terms of infectivity, feeding cessation and speed of...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2014-04-01 00:00:00
abstract：:Getting higher yields of monoclonal antibody (MAb) is a problem in Hybridoma Technology which has two major bottlenecks--(a) poor yield of hybridized cells; and (b) low cellular productivity of MAb in culture. There are three ways of obtaining high MAb yield in vitro--(a) large scale culture of hybrid cells; (b) high ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：1998-02-01 00:00:00
abstract：:The aim of the present study was to investigate the role of phosphodiesterase (PDE) enzyme inhibitors namely rolipram and theophylline in pain and inflammation in experimental animals. Rolipram, a selective PDE IV inhibitor and theophylline a nonspecific PDE inhibitor exerted dose dependent analgesic and anti-inflamma...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The mechanism of uterine muscle contraction stimulated by a triterpenoid glycoside (dalsaxin) isolated from the root of D. saxatilis was investigated by in vitro methods in the rat. Dalsaxin caused a dose-related increase in uterine muscle contraction. The contraction was single and transient and was abolished by mode...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Antinociceptive activity of methanolic extract of leaves of A. aspera was studied by peripheral/non-narcotic model of nociception like acetic acid induced writhing syndrome test and central/narcotic models like hot plate and tail flick tests. The methanolic extract of the plant, administered orally (@ 300, 600 and 900...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：:Poor development and differentiation of three layered cytoarchitectural pattern of brain, degenerating pyramidal cells with pyknotic nuclei and substantial loss of both large and small pyramidal cells of the hippocampal CA1 region were observed in fetuses of pregnant Charles-Foster rats exposed to single high dose of ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:In the present study, cell lysate and cell supernatant of the both strains i.e., virulent wild type (E156) and mutant (S30) vaccine strains of Salmonella enterica subspecies enterica serovar Abortusequi (S. Abortusequi), grown under varied in vivo and in vitro conditions were subjected to SDS PAGE and western blotting...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:Development of knowledge on lipids has attracted the scientific community for the effective utilization of the natural and synthetic lipids. Bioavailability of poorly water soluble drugs from gastrointestinal tract (GIT) can be enhanced by formulating the drugs in lipid based formulations. This formulation can increas...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：:The role of magnesium (Mg2+) in the metabolism of Staphylococcus aureus was studied using a chemically defined medium. At least 0.01 mM Mg2+ was required for any growth of S. aureus. Increasing concentration of Mg2+ up to 1.6mM steadily increased the bacterial growth. Glucose utilisation and acid production were also ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Wheat peptides (0.5 to 3 KDa M(r)) mimick hormonal activity like that of gibberellins and forced open dark closed stomata. The deionized amphoteric peptides solution after passing through cation and anion exchanger resins was run through Amicon's ultrafilters, 10, 3 and 0.5 kDa (M(r)) cut off system. The 3 to 0.5 kDa ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:A protocol for high frequency production of somatic embryos was worked out in pigeonpea, Cajanus cajan (L.) Millsp. The protocol involved sequential employment of embryogenic callus cultures, low density cell suspension cultures and a novel microdroplet cell culture system. The microdroplet cell cultures involved cult...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：:Anabaena oryzae ARM 570 was examined for its growth (chlorophyll and protein), heterocyst frequency, nitrogenase (acetylene reduction) activity, ammonia excretion, and glutamine synthetase and nitrate reductase in response to two levels of urea-N vis-à-vis N2-N. Growth of cyanobacterium increased with duration of incu...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：:In normal conditions, the temporal organization of blood pressure (BP) is mainly controlled by neuroendocrine mechanisms. Above all, the monoaminergic systems (including variations in activity of the autonomous nervous system, and in secretion of biogenic amines) appear to integrate the major driving factors of tempor...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2014-05-01 00:00:00
abstract：:Sulforaphane, a constituent of broccoli was investigated for its antimutagenic potential against different classes of cooked food mutagens (heterocyclic amines). These include imidazoazaarenes such as 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), 2-amino-3,8-dimethyl...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanolic (EE) extracts (50-200 or 200 mg/kg, i.p. or 200 mg/kg, p.o.) of dried Abies pindrow leaves, given 30-45 min before showed significant anti-inflammatory (both against acute and sub-acute models), analgesic, barbiturate hypnosis potentiation...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1998-02-01 00:00:00
abstract：:Leukotrienes play a part in inflammatory response. The unique role of the enzyme 5-lipoxygenase (5-LOX) in the production of leukotrienes makes it a likely therapeutic target for inflammatory conditions like asthma, rheumatoid arthritis, psoriasis, and inflammatory bowel disease (IBD). The aim of the present study was...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:Ruminal fungal isolates (Orpinomyces sp.; C-14, Piromyces sp.; C-15, Orpinomyces sp.; B-13 and Anaeromyces sp.; B-6), were evaluated under anoxic conditions for their effect on in vitro dry matter digestibility, neutral detergent fibre, acid detergent fibre and acid detergent lignin using rice and wheat straw as subst...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：:A set of 25 Kanagawa(+) and Kanagawa(-) strains of V. parahaemolyticus was studied for their ability to degrade hydrocarbons in minimal media. All strains gave positive results with respect to crystal violet (CV), methyl violet, liquid paraffin, benzene, naphthalene and phenol. The CV double ring (CVDR) response had e...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:A strain of T. chilonis, an egg parasitoid of lepidopteran pests tolerant to the most commonly used cyclodiene insecticide--endosulfan was developed in the laboratory. Tolerance to endosulfan was induced by exposing adult parasitoids sequentially from a sub-lethal concentration (0.004%) to the field recommended concen...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:Lipopolysaccharide (LPS) and ratio-detoxified LPS (Rd-LPS) from Salmonella typhimurium were analysed for their ability to stimulate murine peritoneal exudate cells (PEC) and macrophages. Rd-LPS induced much more inflammatory response as compared to LPS. PEC numbers/mouse obtained were significantly higher (3-fold) in ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:Incidence of obesity and diabetes is increasing at an alarming rate not only among the populations of the affluent nations but also amongst the populations of the developing nations. Understanding the mechanisms that cause the onset of these pathological conditions is a requisite to effectively tackling this problem. ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章,评审
doi：
更新日期：2000-09-01 00:00:00
abstract：:Protective effect of sex steroid hormones on aflatoxin-induced cytotoxicity on RBC (hemolysis) was examined in vitro. Addition of aflatoxin (2 micrograms/ml) in RBC suspension caused significant increase in hemolysis. Concurrent addition of aflatoxin (2 micrograms/ml) and estradiolbenzoate (100-1200 pg/ml) in RBC susp...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:EHb-a herbo-mineral formulations of iron (ferrous form) produced a significantly higher and dose dependent increase in the haemoglobin level, as compared to Fefol (a non-complex-chelated iron preparation). Also, EHb did not produce any overt toxicity or gastric irritation at these dose levels. The results suggest that...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：:Leaves of P. sativum the double mutant genotype tendril-less (tl) leaflet-development (lld), due to the action of lld mutation, produce many leaflets that are aborted at different stages of development. Morphological, vein pattern and histological observations showed that aborted leaflets became cup/bell/trumpet (cup)...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2013-06-01 00:00:00
abstract：:Several varieties of peptone supported growth of A. culbertsoni to different extents reaching a maximum cell density of 1-2 X 10(6)/ml. Proteose peptone and tryptone also yielded good growth when combined with thiamine and vitamin B12. A combination of proteose peptone with glucose, yeast extract and salts promoted ex...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:Aerobic and microaerobic diazotrophs possess numerous oxygen restriction strategies to protect nitrogenase from inactivation by oxygen without interfering with energy generation through oxidative phosphorylation. Protection by conformational change in nitrogenase was first detected and described in Azotobacter. This s...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：:Fructose-fed rats were more susceptible to peroxidative damage as measured by thiobarbituric acid reactive species. The concentrations of lipid peroxides, diene conjugates, lipofuscin and hydroperoxides were significantly higher. The levels of enzymic antioxidants such as vitamin C, vitamin E and glutathione and activ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：:The present method involves conversion of the aldehyde produced, as a result of serotonin deamination by monoamine oxidase, to its 2:4 dinitrophenyl hydrazone derivative which gives a stable, bright yellow colour in alkaline solution and can be measured colorimetrically. The derivative is however unstable in the acidi...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Hypoprolactinemia inhibited epididymal energy metabolism and steroidogenesis and retarded growth of epididymal structure. Hyperprolactinemia promoted the above parameters. Bromocriptine had no direct effect on epididymis, while prolactin directly influenced the tissue metabolism. The epididymal maturation seems to be ...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：:Satavari mandur (SM) is a herbo-mineral preparation containing Asparagus racemosus, which finds mention in ancient Indian texts for treatment of gastric ulcers. The ulcer protective effect of SM, 125-500 mg/kg given orally, twice daily for three, five and seven days, was studied on cold restraint stress-induced gastri...
journal_title：Indian journal of experimental biology
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
