Abstract:
:The effects of using several nicotine replacement treatments on self-reported withdrawal symptoms and side effects during 2-day periods of smoking cessation, with 5 days of ad lib smoking between cessation days, were evaluated. Participants (N = 18) experienced the following conditions: nicotine gum, 24-hr patch, 16-hr patch, 24-hr patch plus gum, double 24-hr patch, and no nicotine replacement. The present study found morning urge to smoke was greater during the 16-hr than during the 24-hr patch condition. Double-patch use resulted in significantly greater insomnia than the smoking baseline and 16-hr patch conditions. The no medication and gum alone conditions resulted in similar withdrawal symptoms, and both tended to result in greater reported withdrawal symptoms than the smoking baseline condition. There were no significant withdrawal symptom differences between the 24-hr, patch-gum, and double-patch conditions. The 24-hr and double-patch conditions were preferred by two thirds of the participants (6 each).
journal_name
Exp Clin Psychopharmacoljournal_title
Experimental and clinical psychopharmacologyauthors
Leischow SJ,Valente SN,Hill AL,Otte PS,Aickin M,Holden T,Kligman E,Cook Gdoi
10.1037//1064-1297.5.1.54subject
Has Abstractpub_date
1997-02-01 00:00:00pages
54-64issue
1eissn
1064-1297issn
1936-2293journal_volume
5pub_type
临床试验,杂志文章,随机对照试验abstract::The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differe...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1037//1064-1297.6.1.96
更新日期:1998-02-01 00:00:00
abstract::Although marijuana is the most commonly used illicit drug in the United States, it is not established whether withdrawal from chronic use results in a clinically significant abstinence syndrome. The present study was conducted to characterize symptoms associated with marijuana withdrawal following chronic use during a...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037//1064-1297.8.4.483
更新日期:2000-11-01 00:00:00
abstract::This study examined prevalence and patterns of co-use of opioids and cocaine in regular users of illicit opioids (N = 729) recruited from 5 Canadian cities. Fifty-seven percent (n = 417) reported having used both opioids and cocaine in the month and week preceding the interview; of these, 73% (n = 304) were able to id...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/1064-1297.13.4.303
更新日期:2005-11-01 00:00:00
abstract::Antipsychotic polypharmacy refers to the clinical practice of treating a patient with two or more antipsychotic drugs concurrently. There is abundant evidence in the clinical literature that treatment with antipsychotic polypharmacy is associated with an increased prevalence of drug side effects compared with monother...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0031228
更新日期:2013-04-01 00:00:00
abstract::Research examining the role of pharmacological therapy in the treatment of children and adolescents with clinical disorders is growing. Clinical disorders that present with comorbid aggression can add a challenge to treatment. Child and adolescent neuropsychiatric disorders associated with aggression include attention...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,评审
doi:10.1037/a0018059
更新日期:2010-04-01 00:00:00
abstract::Methylphenidate (MPH) is one of the most widely prescribed drugs for treating attention-deficit hyperactivity disorder. Previous research suggested that MPH is a reinforcer for rats, but not all of the manipulations to show that lever pressing is controlled by the contingency to obtain MPH have been examined. In Exper...
journal_title:Experimental and clinical psychopharmacology
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doi:10.1037/a0019814
更新日期:2010-06-01 00:00:00
abstract::The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...
journal_title:Experimental and clinical psychopharmacology
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doi:10.1037/pha0000186
更新日期:2018-06-01 00:00:00
abstract::Benzodiazepines and alcohol are widely used psychoactive substances that have performance-impairing effects. Research suggests that the impairment profiles for benzodiazepines and alcohol differ, although few cognitive psychopharmacological studies have directly compared these drugs. This double-blind, double-dummy, p...
journal_title:Experimental and clinical psychopharmacology
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更新日期:2010-02-01 00:00:00
abstract::Delay discounting, reflected in the tendency to prefer immediate rewards over delayed rewards, is associated with most forms of problematic substance use. When assessed multiple times to examine within-individual changes, for example, following acute drug administration or an intervention, shifts in delay discounting ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/pha0000211
更新日期:2018-10-01 00:00:00
abstract::The present study investigated the effects of chronic pre-exposure to methamphetamine on sexual motivation and performance in male Japanese quail. Quail were pre-exposed to methamphetamine (1.0 or 3.0 mg/kg ip) or saline (ip) once daily for 10 days and locomotor activity was measured. After a 10 day washout period, se...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0014505
更新日期:2009-02-01 00:00:00
abstract::The accurate assessment of nicotine withdrawal is important theoretically and clinically. A 28-item scale, the Wisconsin Smoking Withdrawal Scale, was developed that contains 7 reliable subscales tapping the major symptom elements of the nicotine withdrawal syndrome. Coefficients alpha for the subscales range from .75...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1999-11-01 00:00:00
abstract::Smoking is among the most important health behaviors linked to premature death and disability among the Latinx population. Yet there is limited understanding of whether transdiagnostic factors like anxiety sensitivity may help explain smoking expectancies among Spanish-speaking Latinx smokers. The present investigatio...
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pub_type: 杂志文章
doi:10.1037/pha0000270
更新日期:2019-12-01 00:00:00
abstract::Maternal smoking is a leading preventable cause of poor pregnancy outcomes and infant morbidity and mortality. Whereas pregnancy has been thought of as a "window of opportunity" when women are more motivated to change health behaviors such as smoking, only 20% of pregnant women quit smoking upon learning they are preg...
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pub_type: 杂志文章
doi:10.1037/1064-1297.14.2.165
更新日期:2006-05-01 00:00:00
abstract::The effect of benzodiazepines on attention has been the object of few investigations. Studies using the spatial cueing paradigm (Posner's paradigm) have reported inconsistent results, which are likely due to methodological and/or dose differences but suggest impaired disengagement of attention from the cue to the targ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/1064-1297.15.1.115
更新日期:2007-02-01 00:00:00
abstract::The high comorbidity of posttraumatic stress disorder (PTSD) and alcohol dependence (AD) has been firmly established. Although laboratory studies have examined self-reported craving in response to trauma and alcohol cues, no studies have reported on alcohol-related physiological responding in response to trauma cues i...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1037/a0019790
更新日期:2010-08-01 00:00:00
abstract::Several studies examining both control and substance-dependent populations have found delay discounting to remain stable over time. In this report, we examine whether delay discounting changes in opioid-dependent individuals who complete a 12-week treatment. The 159 subjects who completed discounting assessments at ba...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0027391
更新日期:2012-08-01 00:00:00
abstract::The consumption of alcohol mixed with energy drinks (AmED) has become a popular and controversial practice among young people. Increased rates of impaired driving and injuries have been associated with AmED consumption. The purpose of this study was to examine if the consumption of AmED alters cognitive processing and...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0026136
更新日期:2012-04-01 00:00:00
abstract::This report describes a novel procedure for computer-controlled drug-dose determination for IV drug self-administration studies. By modifying the duration of each infusion of a single concentration of a drug solution, five or more unit doses (mg/kg/inj) can be dispensed from the same syringe. The advantages of this pr...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0023037
更新日期:2011-04-01 00:00:00
abstract::Previous research has shown that social drinkers continue to show attentional bias toward alcohol-related stimuli even after consuming a moderate dose of alcohol. In contrast, little is known about how alcohol acutely affects attentional bias in groups at risk to develop alcohol-related problems, such as adults with a...
journal_title:Experimental and clinical psychopharmacology
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更新日期:2012-04-01 00:00:00
abstract::Existing literature supports the five-factor model (FFM) of personality (i.e., Extraversion, Agreeableness, Conscientiousness, Emotional Stability, and Intellect or Openness) as a comprehensive representation of stable aspects of mood, affect, and behavior. This study evaluated the FFM as a framework for both self-per...
journal_title:Experimental and clinical psychopharmacology
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更新日期:2014-06-01 00:00:00
abstract::Evidence suggests that smoking to cope among adolescents is associated with a number of problematic outcomes (e.g., greater smoking frequency, higher rates of dependence). It is thus imperative to better understand factors that may increase the likelihood of smoking to cope among adolescents. Research suggests anxiety...
journal_title:Experimental and clinical psychopharmacology
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更新日期:2016-06-01 00:00:00
abstract::Some abused drugs have been reported to alter performance on naturalistic tasks such as driving and also on laboratory tasks. The performance effects of several drug classes were examined using a repeated measures design. Eight volunteers were administered 2 doses of ethanol, marijuana, amphetamine, hydromorphone, pen...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1037//1064-1297.5.3.235
更新日期:1997-08-01 00:00:00
abstract::Aerobic exercise can acutely reduce cigarette cravings during periods of nicotine deprivation. The primary aim of this study was to assess the differential effects of light and vigorous intensity aerobic exercise on cigarette cravings, subjective and physiological reactivity to smoking cues, and affect after overnight...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0032768
更新日期:2013-06-01 00:00:00
abstract::This study targeted poly-drug (cocaine plus heroin) abstinence among buprenorphine-maintained participants with a 12-week voucher-based reinforcement therapy (VBRT) phase versus a yoked control condition. Baseline levels of cocaine and heroin use were significant predictors of treatment outcome, regardless of treatmen...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1037//1064-1297.8.2.176
更新日期:2000-05-01 00:00:00
abstract::In this study, crack/cocaine-dependent (CD) and non-drug-using matched control (MC) participants were presented with hypothetical immediate and delayed rewards, with 16 delay conditions ranging from 5 min to 25 years. All participants were presented with hypothetical monetary rewards; however, the CD group was also pr...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1037//1064-1297.11.1.18
更新日期:2003-02-01 00:00:00
abstract::Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0024141
更新日期:2011-08-01 00:00:00
abstract::This study analyzed whether a contingency management (CM) for shaping cessation period implemented prior to an abstinence-only period (CMS) improves outcomes relative to CM that reinforces only a fixed abstinence criteria (CMA) among treatment-seeking patients in a community setting. A total of 110 patients were rando...
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pub_type: 杂志文章,随机对照试验
doi:10.1037/pha0000269
更新日期:2019-12-01 00:00:00
abstract::It is becoming increasingly evident that the sex of an organism is a critical determinant of responsiveness to opioid analgesics. However, the factors that determine the magnitude and direction of sex differences in opioid antinociception have not been fully elucidated. One factor that has received attention is the re...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,评审
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更新日期:2006-02-01 00:00:00
abstract::In an elegant series of experiments, F. Leri and J. Stewart (2002) report that exposure to heroin increases subsequent reinstatement responding if the animal has access to the drug lever during the lapse and if responding on the lever results in the presentation of conditioned cues. It is interesting that exposure to ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 评论,杂志文章
doi:10.1037//1064-1297.10.4.356
更新日期:2002-11-01 00:00:00
abstract::P. R. Giancola's (2000) macroconstruct framework of executive functions (EF) characterizes how cognitive processes work together to inhibit aggressive responding in provocative situations, and how alcohol intoxication increases the likelihood of aggression by disrupting these processes. His framework can be considered...
journal_title:Experimental and clinical psychopharmacology
pub_type: 评论,杂志文章
doi:10.1037//1064-1297.8.4.598
更新日期:2000-11-01 00:00:00