The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.

abstract：:Muscle force is generated by myosin crossbridges interacting with actin. As estimated from stiffness and equatorial X-ray diffraction of muscle and muscle fibres, most myosin crossbridges are attached to actin during isometric contraction, but a much smaller fraction is bound stereospecifically. To determine the fract...

journal_title：Nature

authors： Bershitsky SY,Tsaturyan AK,Bershitskaya ON,Mashanov GI,Brown P,Burns R,Ferenczi MA

更新日期：1997-07-10 00:00:00

abstract：:Transection of a sensory nerve in adults results in profound abnormalities in sensory perception, even if the severed nerve is surgically repaired to facilitate accurate nerve regeneration. In marked contrast, fewer perceptual errors follow nerve transection and surgical repair in children. The basis for this superior...

journal_title：Nature

authors： Florence SL,Jain N,Pospichal MW,Beck PD,Sly DL,Kaas JH

更新日期：1996-05-02 00:00:00

abstract：:Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencies (in the range of 0.1-4.8%) and effects of up to 2 centimetres per a...

journal_title：Nature

authors： Marouli E,Graff M,Medina-Gomez C,Lo KS,Wood AR,Kjaer TR,Fine RS,Lu Y,Schurmann C,Highland HM,Rüeger S,Thorleifsson G,Justice AE,Lamparter D,Stirrups KE,Turcot V,Young KL,Winkler TW,Esko T,Karaderi T,Locke AE,Mas

更新日期：2017-02-09 00:00:00

abstract：:Direct dating of ductile shear zones and calculation of uplift/exhumation rates can be done using various radiometric dating techniques. But radiometric dating of shallow crustal faulting, which occurs in the crust's brittle regime, has remained difficult because the low temperatures typical of shallow crusted faults ...

journal_title：Nature

authors： van der Pluijm BA,Hall CM,Vrolijk PJ,Pevear DR,Covey MC

更新日期：2001-07-12 00:00:00

abstract：:On being heated, ice melts into liquid water. Although in practice this process tends to be heterogeneous, it can occur homogeneously inside bulk ice. The thermally induced homogeneous melting of solids is fairly well understood, and involves the formation and growth of melting nuclei. But in the case of water, resili...

journal_title：Nature

authors： Mochizuki K,Matsumoto M,Ohmine I

更新日期：2013-06-20 00:00:00

abstract：:The Indian Ocean dipole is a prominent mode of coupled ocean-atmosphere variability, affecting the lives of millions of people in Indian Ocean rim countries. In its positive phase, sea surface temperatures are lower than normal off the Sumatra-Java coast, but higher in the western tropical Indian Ocean. During the ext...

journal_title：Nature

authors： Cai W,Santoso A,Wang G,Weller E,Wu L,Ashok K,Masumoto Y,Yamagata T

更新日期：2014-06-12 00:00:00

abstract：:The origin and growth of magnetic fields in galaxies is still something of an enigma. It is generally assumed that seed fields are amplified over time through the dynamo effect, but there are few constraints on the timescale. It was recently demonstrated that field strengths as traced by rotation measures of distant (...

journal_title：Nature

authors： Bernet ML,Miniati F,Lilly SJ,Kronberg PP,Dessauges-Zavadsky M

更新日期：2008-07-17 00:00:00

abstract：:In myelinated nerves, segregation of voltage-dependent sodium channels to nodes of Ranvier is crucial for saltatory conduction along axons. As sodium channels associate and colocalize with ankyrin at nodes of Ranvier, one possibility is that sodium channels are recruited and immobilized at axonal sites which are speci...

journal_title：Nature

authors： Joe EH,Angelides K

更新日期：1992-03-26 00:00:00

abstract：:A search for general regulators of cancer metastasis has yielded a set of microRNAs for which expression is specifically lost as human breast cancer cells develop metastatic potential. Here we show that restoring the expression of these microRNAs in malignant cells suppresses lung and bone metastasis by human cancer c...

journal_title：Nature

authors： Tavazoie SF,Alarcón C,Oskarsson T,Padua D,Wang Q,Bos PD,Gerald WL,Massagué J

更新日期：2008-01-10 00:00:00

abstract：:Marine records of sediment oxygen isotope compositions show that the Earth's climate has gone through a succession of glacial and interglacial periods during the past million years. But the interpretation of the oxygen isotope records is complicated because both isotope storage in ice sheets and deep-water temperature...

journal_title：Nature

authors： Bintanja R,van de Wal RS,Oerlemans J

更新日期：2005-09-01 00:00:00

abstract：:Contraction of cardiac muscle depends on a transient rise of intracellular calcium concentration ([Ca2+]i) which is initiated by the action potential. It has, however, also been suggested that [Ca2+]i can fluctuate in the absence of changes in membrane potential. The evidence for this is indirect and comes from observ...

journal_title：Nature

authors： Orchard CH,Eisner DA,Allen DG

更新日期：1983-08-25 00:00:00

abstract：:Body size is intrinsically linked to metabolic rate and life-history traits, and is a crucial determinant of food webs and community dynamics1,2. The increased temperatures associated with the urban-heat-island effect result in increased metabolic costs and are expected to drive shifts to smaller body sizes 3 . Urban ...

journal_title：Nature

authors： Merckx T,Souffreau C,Kaiser A,Baardsen LF,Backeljau T,Bonte D,Brans KI,Cours M,Dahirel M,Debortoli N,De Wolf K,Engelen JMT,Fontaneto D,Gianuca AT,Govaert L,Hendrickx F,Higuti J,Lens L,Martens K,Matheve H,Matthysen

更新日期：2018-06-01 00:00:00

abstract：:The main function of postural nervous mechanisms in different species, from mollusc to man, is to counteract the force of gravity and stabilize body orientation in space. Here we investigate the basic principles of postural control in a simple animal model, the marine mollusc Clione limacina. When swimming, C. limacin...

journal_title：Nature

authors： Deliagina TG,Arshavsky YI,Orlovsky GN

更新日期：1998-05-14 00:00:00

abstract：:The opening and closing of voltage-activated Na+, Ca2+ and K+ (Kv) channels underlies electrical and chemical signalling throughout biology, yet the structural basis of voltage sensing is unknown. Hanatoxin is a tarantula toxin that inhibits Kv channels by binding to voltage-sensor paddles, crucial helix-turn-helix mo...

journal_title：Nature

authors： Phillips LR,Milescu M,Li-Smerin Y,Mindell JA,Kim JI,Swartz KJ

更新日期：2005-08-11 00:00:00

abstract：:This corrects the article DOI: 10.1038/nature22794. ...

journal_title：Nature

authors： Shaffer SM,Dunagin MC,Torborg SR,Torre EA,Emert B,Krepler C,Beqiri M,Sproesser K,Brafford PA,Xiao M,Eggan E,Anastopoulos IN,Vargas-Garcia CA,Singh A,Nathanson KL,Herlyn M,Raj A

更新日期：2018-03-08 00:00:00

abstract：:Memory formation is a multi-stage process that initially requires cellular consolidation in the hippocampus, after which memories are downloaded to the cortex for maintenance, in a process termed systems consolidation. Epigenetic mechanisms regulate both types of consolidation, but histone variant exchange, in which c...

journal_title：Nature

authors： Zovkic IB,Paulukaitis BS,Day JJ,Etikala DM,Sweatt JD

更新日期：2014-11-27 00:00:00

abstract：:The ability to recognize information that is incongruous with previous experience is critical for survival. Novelty signals have therefore evolved in the mammalian brain to enhance attention, perception and memory1,2. Although the importance of regions such as the ventral tegmental area3,4 and locus coeruleus5 in broa...

journal_title：Nature

authors： Chen S,He L,Huang AJY,Boehringer R,Robert V,Wintzer ME,Polygalov D,Weitemier AZ,Tao Y,Gu M,Middleton SJ,Namiki K,Hama H,Therreau L,Chevaleyre V,Hioki H,Miyawaki A,Piskorowski RA,McHugh TJ

更新日期：2020-10-01 00:00:00

abstract：:Mammal-like reptiles of the order Therapsida document the emergence of mammals from more primitive synapsids and are of unique zoological and palaeontological interest on that account. Therapsids, first appearing in the Early Permian, were thought to become extinct in the Middle Jurassic, soon after the Late Triassic ...

journal_title：Nature

authors： Fox RC,Youzwyshyn GP,Krause DW

更新日期：1992-07-16 00:00:00

abstract：:Quantum superposition lies at the heart of quantum mechanics and gives rise to many of its paradoxes. Superposition of de Broglie matter waves' has been observed for massive particles such as electrons, atoms and dimers, small van der Waals clusters, and neutrons. But matter wave interferometry with larger objects has...

journal_title：Nature

authors： Arndt M,Nairz O,Vos-Andreae J,Keller C,van der Zouw G,Zeilinger A

更新日期：1999-10-14 00:00:00

abstract：:SAMHD1, an analogue of the murine interferon (IFN)-γ-induced gene Mg11 (ref. 1), has recently been identified as a human immunodeficiency virus-1 (HIV-1) restriction factor that blocks early-stage virus replication in dendritic and other myeloid cells and is the target of the lentiviral protein Vpx, which can relieve ...

journal_title：Nature

authors： Goldstone DC,Ennis-Adeniran V,Hedden JJ,Groom HC,Rice GI,Christodoulou E,Walker PA,Kelly G,Haire LF,Yap MW,de Carvalho LP,Stoye JP,Crow YJ,Taylor IA,Webb M

更新日期：2011-11-06 00:00:00

abstract：:Since 1814, when rubella was first described, the origins of the disease and its causative agent, rubella virus (Matonaviridae: Rubivirus), have remained unclear1. Here we describe ruhugu virus and rustrela virus in Africa and Europe, respectively, which are, to our knowledge, the first known relatives of rubella viru...

journal_title：Nature

authors： Bennett AJ,Paskey AC,Ebinger A,Pfaff F,Priemer G,Höper D,Breithaupt A,Heuser E,Ulrich RG,Kuhn JH,Bishop-Lilly KA,Beer M,Goldberg TL

更新日期：2020-10-01 00:00:00

abstract：:The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are ...

journal_title：Nature

authors： Clemons WM Jr,May JL,Wimberly BT,McCutcheon JP,Capel MS,Ramakrishnan V

更新日期：1999-08-26 00:00:00

abstract：:Observations of galaxies and primordial radiation suggest that the Universe is made mostly of non-luminous dark matter1,2. Several new types of fundamental particle have been proposed as candidates for dark matter3, such as weakly interacting massive particles (WIMPs)4,5. These particles would be expected to interact ...

journal_title：Nature

authors： COSINE-100 Collaboration.

更新日期：2018-12-01 00:00:00

abstract：:Nuclear pore complexes (NPCs) fuse the inner and outer membranes of the nuclear envelope. They comprise hundreds of nucleoporins (Nups) that assemble into multiple subcomplexes and form large central channels for nucleocytoplasmic exchange1,2. How this architecture facilitates messenger RNA export, NPC biogenesis and ...

journal_title：Nature

authors： Allegretti M,Zimmerli CE,Rantos V,Wilfling F,Ronchi P,Fung HKH,Lee CW,Hagen W,Turoňová B,Karius K,Börmel M,Zhang X,Müller CW,Schwab Y,Mahamid J,Pfander B,Kosinski J,Beck M

更新日期：2020-10-01 00:00:00

abstract：:The Earth's convecting upper mantle can be viewed as comprising three main reservoirs, beneath the Pacific, Atlantic and Indian oceans. Because of the uneven global distribution and migration of ridges and subduction zones, the surface area of the Pacific reservoir is at present contracting at about 0.6 km2 x y(r-1), ...

journal_title：Nature

authors： Pearce JA,Leat PT,Barker PF,Millar IL

更新日期：2001-03-22 00:00:00

abstract：:Y chromosomes underlie sex determination in mammals, but their repeat-rich nature has hampered sequencing and associated evolutionary studies. Here we trace Y evolution across 15 representative mammals on the basis of high-throughput genome and transcriptome sequencing. We uncover three independent sex chromosome orig...

journal_title：Nature

authors： Cortez D,Marin R,Toledo-Flores D,Froidevaux L,Liechti A,Waters PD,Grützner F,Kaessmann H

更新日期：2014-04-24 00:00:00

abstract：:Oxygen isotope analyses of Spondylus shells from neolithic sites suggest that the source for the shells used as ornaments in the Balkans and central Europe during the fourth millennium BC was the Aegean and not the Black Sea. The trade in Spondylus may have taken the form of an exchange of gifts. ...

journal_title：Nature

authors： Shackleton N,Renfrew C

更新日期：1970-12-12 00:00:00

abstract：:Transposable elements from prokaryotic and eukaryotic organisms are discrete DNA segments bounded by inverted or directly repeated sequences that insert into non-homologous DNA in a reaction that is independent of the general recombination functions of the host. The mechanisms proposed generally involve a staggered do...

journal_title：Nature

authors： Murphy E,Löfdahl S

更新日期：1984-01-19 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, is characterized by elevated glycogen levels and fat deposition. These consistent metabolic alterations are associated with normoxic stabilization of hypoxia-inducible factors (HIFs) secondary to von Hippel-Lindau (VHL) mutations that occu...

journal_title：Nature

authors： Li B,Qiu B,Lee DS,Walton ZE,Ochocki JD,Mathew LK,Mancuso A,Gade TP,Keith B,Nissim I,Simon MC

更新日期：2014-09-11 00:00:00

abstract：:Melting processes in the deep mantle have important implications for the origin of the deep-derived plumes believed to feed hotspot volcanoes such as those in Hawaii. They also provide insight into how the mantle has evolved, geochemically and dynamically, since the formation of Earth. Melt production in the shallow m...

journal_title：Nature

authors： Andrault D,Petitgirard S,Lo Nigro G,Devidal JL,Veronesi G,Garbarino G,Mezouar M

更新日期：2012-07-18 00:00:00