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Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.

Abstract：

:The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.

journal_name

Nature

journal_title

Nature

authors

Clemons WM Jr,May JL,Wimberly BT,McCutcheon JP,Capel MS,Ramakrishnan V

doi

10.1038/23631

keywords:

subject

Has Abstract

pub_date

1999-08-26 00:00:00

pages

833-40

issue

6747

eissn

0028-0836

issn

1476-4687

journal_volume

400

pub_type

杂志文章

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