Abstract:
:The subgingival microflora was assessed by means of dark field microscopy in 106 pockets of 47 subjects with long-term insulin-dependent diabetes mellitus (IDD). The microbiota of 55 healthy sulci (probing depth < 4 mm) and 51 periodontally diseased (probing depth > or = 4 and 6 mm) pockets were analyzed. The mean duration of the IDD of the diabetic subjects was 23.7 years (range from 10 to 41 years). The diabetic patients, aged 30-65 years, were under medical treatment at the III Department of Medicine, University of Helsinki Central Hospital, and at 2 clinics of the Helsinki Health Centre. Based upon their long-term medical records, 26 subjects were assessed to have poorly controlled insulin-dependent diabetes mellitus (PIDD) and 21 had controlled insulin-dependent diabetes (CIDD). The PIDD subjects exhibited higher mean blood glucose levels (12.9 +/- 4.6 mmol/l, mean +/- S.D.) than the CIDD subjects (7.9 +/- 3.6 mmol/l) (p < 0.001, t-test). The mean glycosylated hemoglobin HBA1 (HBA1c) levels were 11.2 +/- 4.6% (10.3 +/- 1.2%) and 8.8 +/- 1.8% (7.7 +/- 1.4%) for PIDD and CIDD subjects, respectively. These differences were statistically significant (p < 0.01 and p < 0.001, t-test). For each individual, site-specific recordings were made for plaque index and bleeding index scores, probing depth, loss of attachment and radiographic loss of alveolar bone. Dark field microscopy analysis of the presence of spirochetes, motile rods, cocci, non-motile rods, filaments and fusiforms was performed in the total of 106 pockets. According to the results of the dark field microscopy, the % of spirochetes and motile rods in the periodontally diseased pockets was significantly higher in the PIDD than in the CIDD subjects (9.2 +/- 13.4% and 10.8 +/- 14.3% versus 4.0 +/- 5.2% and 3.1 +/- 3.2%, p < 0.01 and p < 0.001, chi 2-test, respectively). Moreover, the PIDD subjects had lower mean %s of coccoid cells in periodontally diseased sites than the CIDD subjects (52.1 +/- 20.8% versus 60.7 +/- 9.0%, p < 0.001, chi 2-test).
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Seppää B,Ainamo Jdoi
10.1111/j.1600-051x.1996.tb00536.xsubject
Has Abstractpub_date
1996-02-01 00:00:00pages
63-7issue
2eissn
0303-6979issn
1600-051Xjournal_volume
23pub_type
杂志文章abstract::The aim of this study was to monitor the presence of sulfate-reducing bacteria (SRB) at different sites in the mouths of both healthy individuals and periodontitis patients. In 20 healthy subjects and 21 periodontitis patients, samples were taken from the palate, vestibulum, dorsum of the tongue, supragingival plaque,...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.1999.260906.x
更新日期:1999-09-01 00:00:00
abstract::HLA DR4 antigens have been considered as a risk factor in periodontal disease. The aim of this "case control" study was to verify and to provide fuller clarification of such data. "Cases" or patients had to be aged between 20 and 48 years. They presented at least 5 sites spread over several teeth with an attachment lo...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.1999.260203.x
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:The substance P (SP) level in human gingival crevicular fluid (GCF) was studied in relation to clinical periodontal variables and to various indicators of host response in the GCF. METHODS:GCF was collected from periodontal sites with gingival inflammation and shallow or moderately deep pocket in 48 subject...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2000.027004262.x
更新日期:2000-04-01 00:00:00
abstract::This paper presents the combined use of decision trees and cost-effectiveness analysis to determine on which patients new diagnostic tests can be useful, and whether they can change the dentist's decision to provide different services and thus improve patient outcomes in 5 different categories of patients. A decision ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1996.tb02089.x
更新日期:1996-03-01 00:00:00
abstract:AIM:To test the hypothesis that a synthetic hydroxyapatite/β-tricalcium phosphate (HA/TCP) construct combined with polyethylene glycol (PEG) hydrogel including recombinant human bone morphogenetic proteins-2 (rhBMP-2) enhances new bone formation compared with bone morphogenetic proteins-2 (BMP-2) delivered using the HA...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12264
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to describe self-reported oral health, oral hygiene habits, and frequency of visits to a dentist among pregnant women in Kuwait. MATERIAL AND METHODS:A cross-sectional study with an anonymous structured questionnaire was distributed among 650 pregnant women during May-June 2003, wh...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2005.00770.x
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND, AIMS:Congenital neutropenia is one condition that may predispose for destructive periodontal disease at a young age. In this report, we describe the microbiology of 3 adolescent patients with congenital neutropenia two of whom suffered from severe periodontitis. METHOD:Microbiological testing of the parent...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2000.027011793.x
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVES:The primary aim was to address the following focused question: What is the clinical effect of laser application compared with mechanical debridement in non-surgical periodontal therapy in patients with chronic periodontitis? A secondary aim was to survey the relevant literature in relation to safety of laser...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1600-051X.2008.01259.x
更新日期:2008-09-01 00:00:00
abstract::Periodontitis is an inflammatory disease of the periodontium which is characterized by a progressive destruction of the tissues supporting the tooth. Its primary etiology is an ill-defined series of microbial infections which may be composed of only some of the more than 300 species of bacteria currently recognized in...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1986.tb01485.x
更新日期:1986-05-01 00:00:00
abstract::The importance of microbial surveillance is illustrated in 3 clinical cases. Each case demonstrated a continued lack of response to conventional periodontal treatment. Repeated bouts of periodontal abscess formation and bone loss occurred over a 3- to 4-year period, despite numerous surgeries supplemented with antibio...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1994.tb00286.x
更新日期:1994-02-01 00:00:00
abstract::The purpose of the study was to examine the relationship between spacing and dental health in 15-year-old adolescents. The whole sample consisted of 156 subjects. Out of them, 74 females and 73 males with 6 anterior teeth made up the study group for examination of the upper jaw. 75 females and 75 males had 6 anterior ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1984.tb01337.x
更新日期:1984-07-01 00:00:00
abstract:AIM:The goal of the present longitudinal cohort study was to examine patterns of periodontal disease progression at progressing sites and subjects defined based on linear mixed models (LMM) of clinical attachment loss (CAL). MATERIALS AND METHODS:A total of 113 periodontally healthy and 302 periodontitis subjects had ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,多中心研究
doi:10.1111/jcpe.12827
更新日期:2018-01-01 00:00:00
abstract:AIM:The primary aim of the study was to systematically map registration records on periodontal medicine in clinical trial registers. The secondary aim was to assess the evolution of periodontal medicine in clinical periodontal research as a whole. MATERIAL AND METHODS:We searched all registration records related to pe...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/jcpe.12534
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND, AIMS:Zinc-citrate-containing toothpastes have previously been suggested to be of value at inhibiting plaque and gingival inflammation. Present formulations have included triclosan which is thought to contribute major antibacterial/antiplaque effects. Alternative antimicrobial agents and other ingredients su...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-051x.2001.028002157.x
更新日期:2001-02-01 00:00:00
abstract:AIM:To assess the effectiveness and clinical performance of early implant placement, 4-8 (Type 2) or 12-16 weeks (Type 3) after extraction, in single anterior sites. METHODS:Studies reporting on Type 2 and Type 3 implant placement were identified. Findings were summarized in evidence tables. Main outcome was implant s...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13092
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of an orally administered probiotic on the oral microbiota. METHODS:A placebo-controlled, parallel study was conducted in 40 gingivitis subjects during 8 weeks. Treatment consisted on the administration of a daily tablet, either containing Lactobacillus reuteri or placebo. Unstimul...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2012.01914.x
更新日期:2012-08-01 00:00:00
abstract::The oral hygiene of habitual chewing stick and toothbrush users who participated in an oral health education (OHE) programme in schools was evaluated. The study comprised all chewing stick users (n = 45) in standard 4 in 8 randomly selected experimental schools and all chewing stick users (n = 17) in standard 4 in 4 r...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051x.1992.tb01157.x
更新日期:1992-08-01 00:00:00
abstract:AIM:The aim of the study was to evaluate the prevalence and simultaneous occurrence of periodontal disease and dental caries in Finnish adults. MATERIAL AND METHODS:The study was performed as part of the nationally representative Health 2000 Survey. The study population was 5255 subjects aged 30 years and older. Probi...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2010.01620.x
更新日期:2010-11-01 00:00:00
abstract::This study was undertaken to test the hypothesis that seeded periodontal ligament cells are able to create new attachment. In one beagle dog, a premolar was removed and scrapings of the ligament were cultured. Artificial periodontal defects were made and the cultured ligament cells were seeded on the planed root surfa...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1991.tb01133.x
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVES:This study examined differences in the efficacy of antibiotics against a single strain of three periodontal pathogens grown in an artificial biofilm. METHODS:Single species biofilms were established with artificial saliva and one of the following bacterial strains: Actinobacillus actinomycetemcomitans Y4, S...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.0303-6979.2004.00490.x
更新日期:2004-05-01 00:00:00
abstract:AIM:The aim of this study was to determine the association between periodontitis and the incidence of preterm birth (PB), low birth weight (LBW) and preterm low birth weight (PLBW) MATERIAL AND METHODS: One thousand and ninety-six women were enrolled. Periodontal data, pregnancy outcome variables and information on oth...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2007.01166.x
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Periodontitis is an infection with an episodic nature of tissue support destruction. The aim of this work was to determine the levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells in periodontal sites characterized by active periodontal connectiv...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2007.01190.x
更新日期:2008-03-01 00:00:00
abstract:AIM:The aim of the present study was to evaluate whether periodontitis is independently associated with oral health-related quality of life (OHRQoL) in individuals with end-stage renal disease (ESRD). MATERIALS AND METHODS:Calibrated examiners assessed 180 adults with ESRD. A full-mouth periodontal examination was per...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13233
更新日期:2020-03-01 00:00:00
abstract:AIM:Our aim was to measure the association of maternal periodontitis with low birth weight (LBW), pre-term LBW, and intra-uterine growth restriction. MATERIAL AND METHODS:An inclusive case-control design including subjects examined for periodontitis through attachment loss, information on perinatal outcomes and genera...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.01012.x
更新日期:2007-01-01 00:00:00
abstract:AIM:This study aims to explore the effect of two commercially available haemostatic agents (i.e., collagen sponge and oxide cellulose) on early healing of the extraction socket. MATERIAL AND METHODS:In a murine model, bilateral maxillary first molars were extracted and the sockets were filled with or without haemostat...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13122
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:The aim of this clinical study was to intra-individually compare Class V restorations of a calcium aluminate cement (CAC), resin composite and enamel with respect to the adjacent levels of interleukin (IL)-1alpha, IL-1beta and IL-1 receptor antagonist (IL-1ra) in gingival crevicular fluid (GCF). The hypothes...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2005.00698.x
更新日期:2005-05-01 00:00:00
abstract::A new periodontitis classification scheme has been adopted, in which forms of the disease previously recognized as "chronic" or "aggressive" are now grouped under a single category ("periodontitis") and are further characterized based on a multi-dimensional staging and grading system. Staging is largely dependent upon...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12946
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Bone morphogenetic proteins (BMPs) have shown considerable promise as a therapeutic agent to enhance periodontal regeneration although the optimal characteristics of a suitable release system are not known. AIM:The aim of this study was to compare the effects of slow and fast degrading gelatin carriers on B...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2001.028004340.x
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to evaluate the role of a combined orthodontic-periodontic treatment in determining the reconstruction of midline papilla lost following periodontitis. MATERIAL AND METHODS:Twenty-eight patients, with infrabony defect and extrusion of one maxillary central incisor, were treat...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.0303-6979.2004.00451.x
更新日期:2004-02-01 00:00:00
abstract::In the present study, radiographs of a model simulating several degrees of alveolar bone height were taken at different vertical projection angles. Bone height was measured by three examiners utilizing a projection technique similar to that originally employed by Björn et al. (1966, 1969). Correlation coefficients of ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1981.tb00896.x
更新日期:1981-12-01 00:00:00