Microbial identification and antibiotic sensitivity testing, an aid for patients refractory to periodontal therapy. A report of 3 cases.

Abstract:

:The importance of microbial surveillance is illustrated in 3 clinical cases. Each case demonstrated a continued lack of response to conventional periodontal treatment. Repeated bouts of periodontal abscess formation and bone loss occurred over a 3- to 4-year period, despite numerous surgeries supplemented with antibiotics. As a result, patients were termed refractory to treatment and extensive microbiological analysis and sensitivity testing was performed. Following institution of the appropriate antibiotic and conservative therapy consisting of several sessions of scaling and root planning, each of these cases demonstrated a dramatic remission of disease progression. No further breakdown has been seen for a minimum of 2 1/2 years. While anecdotal in nature, these cases support the usefulness of microbial identification coupled with antibiotic sensitivity as an adjunct to conventional conservative periodontal therapy.

journal_name

J Clin Periodontol

authors

Fine DH

doi

10.1111/j.1600-051x.1994.tb00286.x

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

98-106

issue

2

eissn

0303-6979

issn

1600-051X

journal_volume

21

pub_type

杂志文章
  • Periodontal reasons for tooth loss in an Asian population.

    abstract::This study analysed data on periodontal reasons for tooth extractions, obtained from 52 dentists practising general dentistry in Singapore. The results revealed that, out of 2172 teeth extracted from 1276 patients, 35.8% were lost due to periodontal disease and 35.4% due to caries. Extraction due to periodontal proble...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1996.tb00550.x

    authors: Ong G

    更新日期:1996-04-01 00:00:00

  • Cellular aspects of and effects on the gingiva in children with Down's syndrome during experimental gingivitis.

    abstract::In a previous experimental gingivitis study, it was shown that in children with Down's syndrome (DS), gingival inflammation started earlier, was more extensive and developed faster, than in normal healthy control children. In both groups, the start of the process was accompanied by an acute inflammatory response and a...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1988.tb01588.x

    authors: Reuland-Bosma W,Liem RS,Jansen HW,van Dijk LJ,van der Weele LT

    更新日期:1988-05-01 00:00:00

  • Prevalence and risk indicators of peri-implantitis in a sample of university-based dental patients in Italy: A cross-sectional study.

    abstract:AIM:Reports regarding prevalence of peri-implant diseases show widely varying prevalence rates, which can be explained partially by variable diagnostic criteria adopted. Furthermore, several different factors have been associated with peri-implant diseases. Hence, the aim of this cross-sectional study is to (a) determi...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13111

    authors: Vignoletti F,Di Domenico GL,Di Martino M,Montero E,de Sanctis M

    更新日期:2019-05-01 00:00:00

  • Frequency distributions of periodontal attachment loss. Clinical and microbiological features.

    abstract::The present investigation attempted to determine if the pattern of past periodontal destruction could be concisely summarized, and related to other clinical and microbiological parameters. 61 subjects between the ages of 12 and 61 years with destructive periodontal disease were evaluated at 6 sites per tooth for redne...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1986.tb00856.x

    authors: Haffajee AD,Socransky SS

    更新日期:1986-07-01 00:00:00

  • Use of chlorhexidine gluconate and povidone iodine mouthwashes in the treatment of acute ulcerative gingivitis.

    abstract::A trial was conducted to compare the effectiveness of povidone iodine and chlorhexidine gluconate with buffered peroxyborate in the treatment of acute ulcerative gingivitis. After 20 patients had entered the trial and 11 had required additional therapy with metronidazole to control their symptoms, the study was termin...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-051x.1978.tb01919.x

    authors: Addy M,Llewelyn J

    更新日期:1978-11-01 00:00:00

  • The comparative effect of acidified sodium chlorite and chlorhexidine mouthrinses on plaque regrowth and salivary bacterial counts.

    abstract::Acidified sodium chlorite (ASC) is recognised as a highly potent, broad spectrum antimicrobial system that has been successfully developed for uses in veterinary, food processing and medical device fields. The current studies aimed to investigate the persistence of antimicrobial action and plaque inhibitory properties...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-051x.1997.tb00236.x

    authors: Yates R,Moran J,Addy M,Mullan PJ,Wade WG,Newcombe R

    更新日期:1997-09-01 00:00:00

  • Efficacy of periodontal plastic surgery procedures in the treatment of localized facial gingival recessions. A systematic review.

    abstract:BACKGROUND:The aim of this Systematic Review (SR) was to assess the clinical efficacy of periodontal plastic surgery procedures in the treatment of localized gingival recessions (Rec) with or without inter-dental clinical attachment loss (iCAL). MATERIAL AND METHODS:Electronic and hand searches were performed to ident...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审

    doi:10.1111/jcpe.12182

    authors: Cairo F,Nieri M,Pagliaro U

    更新日期:2014-04-01 00:00:00

  • Subgingival ultrasonic instrumentation of residual pockets irrigated with essential oils: a randomized controlled trial.

    abstract:AIM:To evaluate the clinical efficacy of subgingival ultrasonic instrumentation irrigated with essential oils (EOs) of residual periodontal pockets. MATERIAL AND METHODS:Sixty-four individuals with chronic periodontitis were invited to participate in this randomized, double-blind, parallel, and placebo-controlled clin...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2011.01725.x

    authors: Feng HS,Bernardo CC,Sonoda LL,Hayashi F,Romito GA,De Lima LA,Lotufo RF,Pannuti CM

    更新日期:2011-07-01 00:00:00

  • Entire papilla preservation technique in the regenerative treatment of deep intrabony defects: 1-Year results.

    abstract:AIM:This study evaluates the clinical outcomes of a novel tunnel-like surgical technique in the treatment of isolated deep intrabony defects. MATERIAL AND METHODS:Twelve patients presenting with at least one isolated deep intrabony defect received regenerative periodontal treatment with "entire papilla preservation (E...

    journal_title:Journal of clinical periodontology

    pub_type:

    doi:10.1111/jcpe.12780

    authors: Aslan S,Buduneli N,Cortellini P

    更新日期:2017-09-01 00:00:00

  • Periodontal pathogens and their role in cardiovascular outcome.

    abstract:AIM:Periodontitis has been identified as a moderate but independent risk factor for cardiovascular (CV) disease and progression. The objective of this study (ClinicalTrials.gov Identifier: NCT01045070) was to assess subgingival colonization with selected periodontal pathogens on the occurrence of further adverse CV eve...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13224

    authors: Schulz S,Schlitt A,Hofmann B,Schaller HG,Reichert S

    更新日期:2020-02-01 00:00:00

  • Clearance of sodium lauryl sulphate from the oral cavity.

    abstract::Sodium lauryl sulphate (SLS) is used in toothpaste and mouth rinses as an emulsifying and surface cleaning agent. SLS has been implicated in an increased incidence of oral irritation in subjects predisposed to recurrent aphthous stomatitis (RAU). Hence, the purpose of this study was to determine the levels of SLS foun...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1997.tb00763.x

    authors: Fakhry-Smith S,Din C,Nathoo SA,Gaffar A

    更新日期:1997-05-01 00:00:00

  • Clinical evaluation of the Er:YAG laser in combination with an enamel matrix protein derivative for the treatment of intrabony periodontal defects: a pilot study.

    abstract:OBJECTIVES:The aim of the present study was to compare the combination therapy of deep intrabony periodontal defects using an Er:YAG laser (ERL) and enamel matrix protein derivative (EMD) to scaling and root planing+ ethylenediaminetetraacetic acid (EDTA)+EMD. MATERIAL AND METHODS:Twenty-two patients with chronic peri...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-051x.2003.00412.x

    authors: Schwarz F,Sculean A,Georg T,Becker J

    更新日期:2003-11-01 00:00:00

  • Mouse model of experimental periodontitis induced by Porphyromonas gingivalis/Fusobacterium nucleatum infection: bone loss and host response.

    abstract:AIM:To compare the effect of oral infection with Porphyromonas gingivalis or Fusobacterium nucleatum versus infection with both bacteria on mouse periodontal tissues, and to characterize the inflammatory response. MATERIALS AND METHODS:Mice were orally infected with P. gingivalis, F. nucleatum or both. At 42 days post...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2009.01393.x

    authors: Polak D,Wilensky A,Shapira L,Halabi A,Goldstein D,Weiss EI,Houri-Haddad Y

    更新日期:2009-05-01 00:00:00

  • Relationship between periapical and periodontal status. A clinical retrospective study.

    abstract::The purpose of the present investigation was to explore possible relationships between clinical periodontal status in periodontally involved teeth with and without endodontic infection. The investigation was conducted as a retrospective study on a consecutive referral population. The periapical conditions in endodonti...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1993.tb00325.x

    authors: Jansson L,Ehnevid H,Lindskog S,Blomlöf L

    更新日期:1993-02-01 00:00:00

  • Effect of root surface alterations on periodontal healing. II. Citric acid treatment of the denuded root.

    abstract::A companion study reported that new connective tissue attachment did not occur to a surgically denuded root surface when transplanted into a normal periodontium. It was the purpose of this study to evaluate periodontal healing adjacent to a citric acid treated denuded root surface. In four squirrel monkeys, 12 teeth w...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1982.tb02105.x

    authors: Polson AM,Proye MP

    更新日期:1982-11-01 00:00:00

  • Eruption cyst formation associated with cyclosporin A.

    abstract:BACKGROUND:Cyclosporin A (CyA) is a potent immunomodulatory agent with a wide range of applications. Despite its therapeutic value, multiple adverse effects of CyA have been identified. This case report describes eruption cyst formation as a possible adverse effect of CyA administration during tooth eruption in a boy t...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1034/j.1600-051x.2003.02028.x

    authors: Kuczek A,Beikler T,Herbst H,Flemmig TF

    更新日期:2003-05-01 00:00:00

  • Evidence grade associating periodontitis with preterm birth and/or low birth weight: II: a systematic review of randomized trials evaluating the effects of periodontal treatment.

    abstract:AIM:The aim of this systematic review was to evaluate whether maternal periodontal disease treatment (MPDT) can reduce the incidence of preterm birth (PB) and/or low birth weight (LBW). METHODS:The Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE were searched for entries up to October 2010 without r...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1600-051X.2011.01761.x

    authors: Chambrone L,Pannuti CM,Guglielmetti MR,Chambrone LA

    更新日期:2011-10-01 00:00:00

  • Soft tissue myxoma: report of an unusual case located on the gingiva.

    abstract:BACKGROUND:Soft tissue myxoma of the oral cavity is rare. Only three cases of myxoma of gingiva have been reported in the literature. We present a case of soft tissue myxoma arising from the left maxillary adherent gingiva in a 42-year-old male [correction of female] patient. METHODS:Histological examination showed sp...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2005.00837.x

    authors: Perrotti V,Rubini C,Fioroni M,Piattelli A

    更新日期:2006-01-01 00:00:00

  • Experimental transient bacteraemias in human subjects with clinically healthy gingivae.

    abstract::Thirty-six subjects with no evidence of clinical gingival inflammation underwent a standardized toothbrushing procedure. Blood specimens, obtained from a vein in the antecubital fossa during the last 30 seconds of brushing, were cultured under aerobic and stringent anaerobic conditions. Three subjects exhibited detect...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1979.tb02288.x

    authors: Silver JG,Martin AW,McBride BC

    更新日期:1979-02-01 00:00:00

  • Flow-cytometric analysis of lymphocyte subsets in patients with advanced periodontitis.

    abstract::Peripheral blood lymphocytes from 36 patients with advanced periodontitis and from 34 healthy subjects were examined using a panel of monoclonal antibodies and fluorescence flow cytometry. The absolute and relative counts of B-cells, T-cells, T-helper (TH), T-suppressor/cytotoxic (TS) cells, activated T-cells and natu...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:

    authors: Zafiropoulos GG,Flores-de-Jacoby L,Schoop B,Havemann K,Heymanns J

    更新日期:1990-10-01 00:00:00

  • Periodontal disease as a risk factor for adverse pregnancy outcomes: a prospective cohort study.

    abstract:AIM:The aim of this study was to determine the association between periodontitis and the incidence of preterm birth (PB), low birth weight (LBW) and preterm low birth weight (PLBW) MATERIAL AND METHODS: One thousand and ninety-six women were enrolled. Periodontal data, pregnancy outcome variables and information on oth...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2007.01166.x

    authors: Agueda A,Ramón JM,Manau C,Guerrero A,Echeverría JJ

    更新日期:2008-01-01 00:00:00

  • Formation and regeneration of a Wnt-responsive junctional epithelium.

    abstract:AIM:To identify the molecular mechanisms mediating the persistent defensive functions of the self-renewing junctional epithelium (JE). MATERIALS AND METHODS:Two strains of Wnt reporter mice, Axin2CreErt2/+ ;R26RmTmG/+ and Axin2LacZ/+ , were employed, along with three clinically relevant experimental scenarios where th...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.13371

    authors: Yuan X,Chen J,Van Brunt LA,Grauer J,Xu Q,Pei X,Wang L,Zhao Y,Helms JA

    更新日期:2020-12-01 00:00:00

  • Extracted tooth roots used for lateral alveolar ridge augmentation: a proof-of-concept study.

    abstract:OBJECTIVES:To assess the efficacy of tooth roots used as autografts for lateral ridge augmentation and two-stage early osseointegration of titanium implants. MATERIAL & METHODS:The maxillary premolars were randomly assigned to either endodontic therapy (PM-E) or were left untreated (PM-C). Retromolar cortical autogeno...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/jcpe.12481

    authors: Schwarz F,Golubovic V,Becker K,Mihatovic I

    更新日期:2016-04-01 00:00:00

  • Prevention and control of dental caries and periodontal diseases at individual and population level: consensus report of group 3 of joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases.

    abstract:BACKGROUND:The non-communicable diseases dental caries and periodontal diseases pose an enormous burden on mankind. The dental biofilm is a major biological determinant common to the development of both diseases, and they share common risk factors and social determinants, important for their prevention and control. The...

    journal_title:Journal of clinical periodontology

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1111/jcpe.12687

    authors: Jepsen S,Blanco J,Buchalla W,Carvalho JC,Dietrich T,Dörfer C,Eaton KA,Figuero E,Frencken JE,Graziani F,Higham SM,Kocher T,Maltz M,Ortiz-Vigon A,Schmoeckel J,Sculean A,Tenuta LM,van der Veen MH,Machiulskiene V

    更新日期:2017-03-01 00:00:00

  • Antibody responses to suspected periodontal pathogens in elderly subjects with periodontal disease.

    abstract::Little is known about the relationship of aging to periodontal disease. The immune response undergoes aging-related changes resulting in loss of functional capacity. The aim of this study was to investigate the relationship between levels of serum IgG antibodies against suspected periodontal pathogenic microorganisms ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1995.tb01782.x

    authors: McArthur WP,Bloom C,Taylor M,Smith J,Wheeler T,Magnusson NI

    更新日期:1995-11-01 00:00:00

  • Crevicular fluid glutathione levels in periodontitis and the effect of non-surgical therapy.

    abstract:AIM:To quantify reduced and oxidized glutathione (GSH and GSSG) levels in gingival crevicular fluid (GCF) of periodontitis patients pre-therapy (versus periodontally healthy controls) and ascertain whether successful non-surgical therapy alters glutathione levels. MATERIALS AND METHODS:Thirty-second GCF samples (6/sub...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2009.01504.x

    authors: Grant MM,Brock GR,Matthews JB,Chapple IL

    更新日期:2010-01-01 00:00:00

  • Mechanical non-surgical treatment of peri-implantitis: a single-blinded randomized longitudinal clinical study. II. Microbiological results.

    abstract:BACKGROUND:Peri-implantitis is common in patients with dental implants. We performed a single-blinded longitudinal randomized study to assess the effects of mechanical debridement on the peri-implant microbiota in peri-implantitis lesions. MATERIALS AND METHODS:An expanded checkerboard DNA-DNA hybridization assay enco...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-051X.2010.01561.x

    authors: Persson GR,Samuelsson E,Lindahl C,Renvert S

    更新日期:2010-06-01 00:00:00

  • Exposure measurement in the association between periodontal disease and prematurity/low birth weight.

    abstract:AIM:To compare the use of different definitions for exposure measurement in cases of association between periodontal disease (PD) and prematurity and/or low birth weight (PLBW). MATERIAL AND METHODS:A database from a previous case-control study was used to compare four different definitions for periodontitis: at least...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051X.2007.01141.x

    authors: Gomes-Filho IS,Cruz SS,Rezende EJ,Dos Santos CA,Soledade KR,Magalhães MA,de Azevedo AC,Trindade SC,Vianna MI,Passos Jde S,Cerqueira EM

    更新日期:2007-11-01 00:00:00

  • Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.

    abstract::The aim of the present study was to characterize the eventual presence and molecular forms of gelatinase/type IV collagenase activities in gingival crevicular fluid (GCF) and saliva in different forms of periodontitis; patients with clinically healthy periodontium served as controls. Enzyme activities were monitored e...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1994.tb00272.x

    authors: Ingman T,Sorsa T,Lindy O,Koski H,Konttinen YT

    更新日期:1994-01-01 00:00:00

  • Local delivery of chemotherapeutic agents in periodontal therapy: has its time arrived?

    abstract::The concept of locally delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章

    doi:10.1111/j.1600-051x.1998.tb02395.x

    authors: Finkelman RD,Williams RC

    更新日期:1998-11-01 00:00:00