Postmenopausal estrogen and heart disease.

abstract：INTRODUCTION:Although the combination of statins with n-3 fatty acids seems to be beneficial under the lipid profile aspect, there is little information about the interaction of these two compounds on oxidative stress. OBJECTIVE:Evaluate the interaction between statins and n-3 fatty acids on oxidative stress in women,...

journal_title：Atherosclerosis

authors： Carrepeiro MM,Rogero MM,Bertolami MC,Botelho PB,Castro N,Castro IA

更新日期：2011-07-01 00:00:00

abstract：:The aortic endothelium of rabbits fed a stock diet containing 1 or 2% cholesterol for intervals of 1 day to 21 weeks was compared with that of normal rabbits on a stock diet without cholesterol. The endothelium was examined en face using the Häutchen technique. The aortic endothelium of the experimental animals reveal...

journal_title：Atherosclerosis

authors： Silkworth JB,McLean B,Stehbens WE

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:Diabetes and atherosclerosis may share common genetic determinants. A prior study in Hispanics found association of haplotypes in the diabetes gene calpain-10 (CAPN10) with carotid artery intima-media thickness (CIMT). This study sought to replicate this association in an independent cohort. METHODS:Four CAP...

journal_title：Atherosclerosis

authors： Goodarzi MO,Taylor KD,Jones MR,Fang B,Guo X,Xiang AH,Buchanan TA,Hodis HN,Raffel LJ,Rotter JI

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Parental history (PH) and genetic risk scores (GRSs) are separately associated with coronary heart disease (CHD), but evidence regarding their combined effects is lacking. We aimed to evaluate the joint associations and predictive ability of PH and GRSs for incident CHD. METHODS:Data for 4283 Cauca...

journal_title：Atherosclerosis

authors： Antiochos P,Marques-Vidal P,McDaid A,Waeber G,Vollenweider P

更新日期：2016-01-01 00:00:00

abstract：:Sitostanol (24-ethyl-5 alpha-cholestan-3 beta-ol), a hydrogenated derivative of sitosterol, was administered in a low dose (1.5 g/day) for 4 weeks to 6 patients with hypercholesterolemia. Total cholesterol was reduced significantly after 3 and 4 weeks by 10 and 15%, respectively. The reduction of total cholesterol was...

journal_title：Atherosclerosis

authors： Heinemann T,Leiss O,von Bergmann K

更新日期：1986-09-01 00:00:00

abstract：:High circulating levels of carotenoids have been thought to exhibit a protective function in the development of atherosclerosis. We investigated whether aortic atherosclerosis was associated with lower levels of the major serum carotenoids in alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein, lycopene, and zea...

journal_title：Atherosclerosis

authors： Klipstein-Grobusch K,Launer LJ,Geleijnse JM,Boeing H,Hofman A,Witteman JC

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Serum γ-glutamyl transferase (GGT) levels are known to be positively associated with obesity. We aimed at verifying an association between baseline GGT levels and the development of obesity in Korean men. PATIENTS AND METHODS:This prospective cohort study was performed on 18,510 initially non-...

journal_title：Atherosclerosis

authors： Suh YJ,Park SK,Choi JM,Ryoo JH

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To examine the association between cardiovascular reactivity to a set of psychological stressors and carotid artery intima-media thickness, a marker of subclinical cardiovascular disease in healthy adolescents. METHODS:Participants were 25 boys and 23 girls age 14.2 ± 0.9 years who were measured for heart ra...

journal_title：Atherosclerosis

authors： Roemmich JN,Feda DM,Seelbinder AM,Lambiase MJ,Kala GK,Dorn J

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Depressed mood and exhaustion (DEEX) have gained attention as a risk predictor for cardiovascular disease (CVD). Studies to estimate its ranking in prediction models are sparse. METHODS:The study included 3428 men aged 45-74 years who participated in one of three population-based MONICA/KORA Augsbu...

journal_title：Atherosclerosis

authors： Ladwig KH,Baumert J,Marten-Mittag B,Lukaschek K,Johar H,Fang X,Ronel J,Meisinger C,Peters A,KORA Investigators.

更新日期：2017-02-01 00:00:00

abstract：:Mitral annulus calcification (MAC) is a chronic, non-inflammatory, degenerative process of the fibrous support structure of the mitral valve. It occurs more often in women and the elderly. MAC is associated with known atherosclerotic risk factors such as diabetes mellitus, hypertension and hypercholesterolemia. It is ...

journal_title：Atherosclerosis

authors： Adler Y,Fink N,Spector D,Wiser I,Sagie A

更新日期：2001-03-01 00:00:00

abstract：:We examined the interactive effect of oxidized low density lipoprotein (LDL) and ascorbic acid on collagen production in cultured smooth muscle cells (SMCs). Porcine aortic SMCs were incubated with 50-200 micrograms/ml of human LDL with/without 5 microM Cu2+ for 24 h. Collagen production was assayed by successive salt...

journal_title：Atherosclerosis

authors： Jimi S,Saku K,Uesugi N,Sakata N,Takebayashi S

更新日期：1995-07-01 00:00:00

abstract：:The ATP-binding cassette transporters, ABCA1 and ABCG1, are LXR-target genes that participate in the removal of cholesterol from lipid-laden macrophages, a crucial anti-atherogenic mechanism. Statins are currently the most efficacious therapy for the treatment of hypercholesterolemia and cardiovascular disease. We and...

journal_title：Atherosclerosis

authors： Wong J,Quinn CM,Gelissen IC,Jessup W,Brown AJ

更新日期：2008-01-01 00:00:00

abstract：:Remnant-like particles (RLPs) are closely associated with coronary heart disease and can induce endothelial dysfunction through oxidative mechanisms. Many risk factors accelerate the onset of endothelial progenitor cells (EPCs) senescence via increased oxidative stress. In this study, we investigated the effect of RLP...

journal_title：Atherosclerosis

authors： Liu L,Wen T,Zheng XY,Yang DG,Zhao SP,Xu DY,Lü GH

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Recent studies have unveiled an association between ADAMTS7 gene variation and coronary artery disease (CAD) caused by atherosclerosis. We investigated if the ADAMTS7 Serine214-to-Proline substitution arising from a CAD-associated variant affected angiogenesis, since neovascularization plays an impo...

journal_title：Atherosclerosis

authors： Pu X,Chan K,Yang W,Xiao Q,Zhang L,Moore AD,Liu C,Webb TR,Caulfield MJ,Samani NJ,Zhu J,Ye S

更新日期：2020-03-01 00:00:00

abstract：:Elevated fibrinogen levels after coronary balloon angioplasty have been reported to be useful in predicting restenosis. Therefore, we sought to evaluate the relationship between preprocedural fibrinogen levels and the 6-12-month outcomes of patients undergoing coronary stenting. Plasma levels of fibrinogen were measur...

journal_title：Atherosclerosis

authors： Otsuka M,Hayashi Y,Ueda H,Imazu M,Kohno N

更新日期：2002-10-01 00:00:00

abstract：:A marked reduction of serum cholesterol was obtained by treatment with probucol in heterozygous as well as in homozygous cases of familial hypercholesterolemia. A strict dietary regimen (low-fat, low-calories) intensified the hypocholesterolemic effect of the drug. The drug was also useful in diminishing the rebound o...

journal_title：Atherosclerosis

authors： Yamamoto A,Matsuzawa Y,Kishino B,Hayashi R,Hirobe K,Kikkawa T

更新日期：1983-08-01 00:00:00

abstract：:An organ culture technique was used to investigate the removal of fatty acids incorporated into various lipid fractions in intimal segments of atherosclerotic rabbit aorta. Segments of aorta were pulse-labelled in vitro with [9,10-3H]oleic acid and [1-14C]linoleic acid for 24 h. The incubation medium was replaced with...

journal_title：Atherosclerosis

authors： Hudson K,Day AJ,Horsch AK

更新日期：1977-12-01 00:00:00

abstract：:Statins produce cholesterol-independent, anti-inflammatory effects, which result at least in part from increased endothelial nitric oxide production. These effects may be modulated by polymorphisms in the endothelial nitric oxide synthase (eNOS) gene. Here, we examined whether the T-786C polymorphism of eNOS gene affe...

journal_title：Atherosclerosis

authors： Souza-Costa DC,Sandrim VC,Lopes LF,Gerlach RF,Rego EM,Tanus-Santos JE

更新日期：2007-08-01 00:00:00

abstract：:The aim of this study was to determine whether an abnormality in low density lipoprotein (LDL) metabolism could be demonstrated in fibroblasts cultured from normolipidaemic subjects with atherosclerosis. Seventeen male subjects aged 30-55 years with normal plasma lipid concentrations were divided into 2 groups on the ...

journal_title：Atherosclerosis

authors： Behrman RG,Wynn V

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:CETP inhibitors block the transfer of cholesteryl ester from HDL-C to VLDL-C and LDL-C, thereby raising HDL-C and lowering LDL-C. In this study, we explored the effect of CETP inhibitors on hepatic LDL receptor (LDLR) and PCSK9 expression and further elucidated the underlying regulatory mechanism. RESULTS:W...

journal_title：Atherosclerosis

authors： Dong B,Singh AB,Fung C,Kan K,Liu J

更新日期：2014-08-01 00:00:00

abstract：:Tendon xanthoma are a hallmark of familial hypercholesterolemia and are among its earliest clinical manifestations. Achilles tendon size, advanced to a generally accepted marker, is virtually specific for the disease and easily accessible for measurement. Hypercholesterolemic patients with coronary heart disease have ...

journal_title：Atherosclerosis

authors： Steinmetz A,Schmitt W,Schuler P,Kleinsorge F,Schneider J,Kaffarnik H

更新日期：1988-12-01 00:00:00

abstract：:Berberine, an alkaloid isolated from Chinese medicinal herbs, long been known for its anti-microbial activity and used to treat various infectious disorders in traditional Chinese medicine. In the present study, we have tested the hypothesis that berberine could inhibit vascular smooth muscle cell (VSMC) proliferation...

journal_title：Atherosclerosis

authors： Lee S,Lim HJ,Park HY,Lee KS,Park JH,Jang Y

更新日期：2006-05-01 00:00:00

abstract：:The effects of niceritrol, a nicotinic acid derivative, on the levels of HDL-cholesterol (HDL-Ch) and a mixture of VLDL- and LDL-Ch (VLDL- + LDL-Ch) were studied in hyperlipidemic patients. Serum total cholesterol (sTC) and serum triglyceride (sTG) were significantly reduced during niceritrol administration. Lipoprote...

journal_title：Atherosclerosis

authors： Kibata M,Ishida M,Asano K,Uehara H,Saito K,Fuchimoto T,Ugaki K,Murakami H,Matoba K,Kotakemori Y,Shirai K,Yoshioka H,Nanba M,Yasuda M,Ishizaki M,Kitagawa N,Ikejiri K,Inohara R,Lee BJ,Saino S,Sakado J,Matuzaka H,

更新日期：1980-11-01 00:00:00

abstract：:The single nucleotide polymorphisms (SNPs) apolipoprotein E (APOE) epsilon3/epsilon2/epsilon4, cholesteryl ester transfer protein (CETP) TaqIB, and apolipoprotein C3 (APOC3) -482 C>T have been associated with an atherogenic lipid profile and, in some studies, with increased cardiovascular risk. However, no data exist ...

journal_title：Atherosclerosis

authors： Muendlein A,Saely CH,Marte T,Schmid F,Koch L,Rein P,Langer P,Aczel S,Drexel H

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The scavenger receptor SR-PSOX/CXCL16, which is identical to the chemokine CXCL16, is thought to be involved in atherogenesis. However, the presence and function of SR-PSOX/CXCL16 in the endothelium of atherosclerotic arteries has not been substantiated. METHODS AND RESULTS:In rabbit aorta immunocytochemistr...

journal_title：Atherosclerosis

authors： Hofnagel O,Engel T,Severs NJ,Robenek H,Buers I

更新日期：2011-08-01 00:00:00

abstract：:ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, significantly reduced both serum cholesterol and phospholipid levels in dogs, when used at a dosage higher than 10 mg/kg per day. Triglyceride levels were not consistently changed, but beta- and pre-beta-lipoproteins were preferentially redu...

journal_title：Atherosclerosis

authors： Tsujita Y,Kuroda M,Tanzawa K,Kitano N,Endo A

更新日期：1979-03-01 00:00:00

abstract：OBJECTIVE:Given the high risk of cardiovascular disease in South Asians and the importance of inflammation in coronary heart disease we tested the hypothesis that circulating C-reactive protein (CRP) and interleukin 6 (IL-6) would be higher in healthy British born infants of South Asian origin than in infants of Europe...

journal_title：Atherosclerosis

authors： Oldroyd JC,Heald A,Bansal N,Vyas A,Siddals K,Gibson M,Clayton P,Cruickshank JK

更新日期：2009-11-01 00:00:00

abstract：:Gender is a strong predictor of coronary heart disease (CHD) susceptibility and reports indicate that males are more likely to develop CHD compared to age-matched premenopausal females. To test whether similar gender differences exist in hamsters, 16 male and 16 female F1B Golden Syrian hamsters, aged 10 weeks, were f...

journal_title：Atherosclerosis

authors： Wilson TA,Nicolosi RJ,Lawton CW,Babiak J

更新日期：1999-09-01 00:00:00

abstract：:Estrogen use is associated with protection from cardiovascular disease in postmenopausal women. This benefit appears to be magnified among women with pre-existing heart disease. The possible bias of intrinsically better health in women using estrogen has not been ruled out in observational studies. Therefore, two doub...

journal_title：Atherosclerosis

authors： Knopp RH,Zhu X,Bonet B

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To investigate the statin eligibility and the predictabilities for cardiovascular disease between AHA/ACC and ATPIII guidelines, comparing those results to concomitant coronary artery calcium scores (CACS) in a large cohort of Korean individuals who met statin-eligibility criteria. METHODS:Among 19,920 parti...

journal_title：Atherosclerosis

authors： Rhee EJ,Park SE,Oh HG,Park CY,Oh KW,Park SW,Blankstein R,Plutzky J,Lee WY

更新日期：2015-05-01 00:00:00