Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Berberine improves neointima formation in a rat model.

abstract：BACKGROUND:Abdominal aortic aneurysm (AAA) is characterized by vascular remodeling with increased infiltration of inflammatory cells and apoptosis/modulation of vascular smooth muscle cells (SMCs). Imatinib is a selective inhibitor of several tyrosine kinases, including PDGF receptors, Abl, and c-kit. The objective of ...

journal_title：Atherosclerosis

authors： Vorkapic E,Dugic E,Vikingsson S,Roy J,Mäyränpää MI,Eriksson P,Wågsäter D

更新日期：2016-06-01 00:00:00

abstract：:Prolonged exposure of rats to cigarette smoke resulted in significant alterations in the metabolism of lipids. There was a significant increase in the concentration of cholesterol, triglycerides and phospholipids in most of the tissues, particularly the heart, aorta and lungs. Cholesterol, triglycerides and phospholip...

journal_title：Atherosclerosis

authors： Latha MS,Vijayammal PL,Kurup PA

更新日期：1988-04-01 00:00:00

abstract：:The effects of the artificial triglyceride-phospholipid emulsion (10% intralipid) on HDL subfraction were studied in vivo. After a 14-h fast, subjects received intralipid via a 4-h infusion. Serum lipoproteins were analyzed before and at 4 and 6 h after the start of the infusion. At 4-h the following acute changes by ...

journal_title：Atherosclerosis

authors： Sakuma N,Lin C,Matsumoto Y,Ikeuchi R,Ichikawa T,Hirata H,Noguchi Y,Fujinami T

更新日期：1988-11-01 00:00:00

abstract：:beta-very low-density lipoprotein (beta-VLDL), a collective term for VLDL and chylomicron remnants, has recently shown to potently promote the development of atherosclerosis. However, the effects of beta-VLDL on the accumulation of nitric oxide (NO) and the expression of inducible NO synthase (iNOS) in vascular smooth...

journal_title：Atherosclerosis

authors： Takahashi M,Takahashi S,Shimpo M,Naito A,Ogata Y,Kobayashi E,Ikeda U,Shimada K

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND AND AIMS:We recently showed that miR-223-3p on high-density lipoproteins (HDL) is exported to endothelial cells, where it inhibits inflammation. However, the origin of miR-223-3p on HDL is unknown. We hypothesize that HDL-associated miR-223-3p originates in myeloid cells and is exported to HDL in a scavenger...

journal_title：Atherosclerosis

authors： Cuesta Torres LF,Zhu W,Öhrling G,Larsson R,Patel M,Wiese CB,Rye KA,Vickers KC,Tabet F

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Peritoneal macrophages are used in many studies related to atherosclerosis. In situ, they are non-adherent and upon culturing, they adhere and function as scavengers of modified lipoproteins and dead apoptotic cells. They also produce growth factors, suggesting that they may provide life-supporting function a...

journal_title：Atherosclerosis

authors： Selvarajan K,Moldovan L,Chandrakala AN,Litvinov D,Parthasarathy S

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIMS:It remains unclear how trans fatty acid (TFA) at low-level intake affect lipid levels and the development of acute coronary syndrome (ACS). The study aimed to investigate how plasma TFA composition differs between male patients with ACS and healthy men. METHODS:Plasma fatty acid (FA) composition (a...

journal_title：Atherosclerosis

authors： Koba S,Takao T,Shimizu F,Ogawa M,Ishii Y,Yokota Y,Furuyama F,Tsunoda F,Shoji M,Harris WS,Takada A

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:In this study, we compared the changes in arterial stiffness in chronic hemodialysis patients treated with 8-h vs. 4-h thrice weekly in-center hemodialysis. METHODS:Sixty prevalent chronic hemodialysis patients assigned to 8-h nocturnal in-center thrice weekly HD (NHD) and 60 control cases assigned to 4-h th...

journal_title：Atherosclerosis

authors： Demirci MS,Celik G,Ozkahya M,Tumuklu M,Toz H,Asci G,Duman S,Basci A,Kircelli F,Ozdogan O,Demirci C,Can L,Isik IO,Ok E,Long Dialysis Group.

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) have been linked with an increased risk of type 2 diabetes, but their relationships with cardiovascular disease (CVD) are uncertain. We aimed to assess the associations of ALT and AST with CVD risk and determine their potential utility for C...

journal_title：Atherosclerosis

authors： Kunutsor SK,Bakker SJ,Kootstra-Ros JE,Blokzijl H,Gansevoort RT,Dullaart RP

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To investigate the association of the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine (ADMA) and coronary endothelial function. METHODS AND RESULTS:In 289 patients with coronary artery disease we assessed coronary endothelium-dependent and -independent vascular responses to intracoro...

journal_title：Atherosclerosis

authors： Maas R,Quitzau K,Schwedhelm E,Spieker L,Rafflenbeul W,Steenpass A,Lüscher TF,Böger RH

更新日期：2007-03-01 00:00:00

abstract：:The aim of this study was to evaluate the cholesterol-lowering and antiatherosclerotic effect of the HMG-CoA reductase inhibitor pravastatin sodium at a dosage comparable to human therapy. Twelve heterozygous WHHL rabbits (13 months old) were fed 100 g per day of a low cholesterol (0.03%) enriched diet for 12 months. ...

journal_title：Atherosclerosis

authors： Harsch M,Braesen JH,Niendorf A

更新日期：1997-02-10 00:00:00

abstract：:To examine a long-term effect of community-based education program for hypercholesterolemia and an effect modification by apolipoprotein E polymorphism, we conducted a 1-year randomized clinical trial with 8 year-follow-up. One hundred four persons aged 40-64 years who had serum total cholesterol levels between 6.21 a...

journal_title：Atherosclerosis

authors： Iso H,Imano H,Nakagawa Y,Kiyama M,Kitamura A,Sato S,Naito Y,Shimamoto T,Iida M

更新日期：2002-09-01 00:00:00

abstract：:Occlusive arterial disease stimulates compensatory growth of pre-existent and new arterial channels which help to maintain organ perfusion. Previous studies characterizing compensatory or collateral vascular growth have been performed in normocholesterolemic animals. Because hyperlipidemic states alter vascular regula...

journal_title：Atherosclerosis

authors： Bucay M,Nguy J,Barrios R,Chen CH,Henry PD

更新日期：1998-08-01 00:00:00

abstract：:We tested whether low high-density lipoprotein cholesterol (HDL-C) and/or high triglycerides are associated to abnormal HDL subclasses distribution and composition, and their relationships with fasting insulin and C-reactive protein (CRP). Four groups of adolescents were studied: group 1 (HDL-C< or =35 mg/dl+TG> or =1...

journal_title：Atherosclerosis

authors： Medina-Urrutia A,Juarez-Rojas JG,Martínez-Alvarado R,Jorge-Galarza E,Posadas-Sánchez R,Cardoso-Saldaña G,Caracas-Portilla N,Mendoza-Perez E,Posadas-Romero C

更新日期：2008-12-01 00:00:00

abstract：:Increased aortic and liver prolyl hydroxylase activity has been suggested as an early biochemical indicator of the fibrotic changes which occur in rabbits with injury induced arteriosclerosis. Daily administration of epinephrine (0.025-0.050 mg/kg, i.v.) and thyroxine (0.050 mg/kg, i.p.) to rabbits for 3 weeks produce...

journal_title：Atherosclerosis

authors： Fuller GC,Matoney AL,Fisher DO,Fausto N,Cardinale GJ

更新日期：1976-09-01 00:00:00

abstract：:Young pigs with hypertension of 10 weeks duration, resulting from cellophane perinephritis, were injected with 125I-labelled low-density lipoprotein ([125I]LDL) before being killed 24 h or 48 h later. Intimal thickening and increased acid mucopolysaccharide were demonstrated in the aortas and major arteries of the hyp...

journal_title：Atherosclerosis

authors： Sharpe DN,Scott PJ,Flint MH,Donald J

更新日期：1980-04-01 00:00:00

abstract：:Enhanced and prolonged postprandial lipaemia is implicated in coronary and carotid artery disease. This study assessed the effects of atorvastatin, a 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor, on postprandial plasma concentrations of triglyceride-rich lipoproteins (TRLs). Sixteen middle-aged men with combined...

journal_title：Atherosclerosis

authors： Boquist S,Karpe F,Danell-Toverud K,Hamsten A

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of resistance training (RT) on the metabolism of an LDL-like nanoemulsion and on lipid transfer to HDL, an important step of HDL metabolism. METHODS:LDL-like nanoemulsion plasma kinetics was studied in 15 healthy men under regular RT for 1-4 years (age = 25 ± 5 years, VO(2)peak = 50 ±...

journal_title：Atherosclerosis

authors： da Silva JL,Vinagre CG,Morikawa AT,Alves MJ,Mesquita CH,Maranhão RC

更新日期：2011-12-01 00:00:00

abstract：:The effect of colestipol on plasma lipids and lipoproteins was studied in children, adolescents and young adults with familial hypercholesterolemia. O.125 g or 0.25 g/kg body weight were given in randomized sequence for period of 4 weeks. Total cholesterol was lowered by 13 and 18% with the smaller and larger dose , r...

journal_title：Atherosclerosis

authors： Schlierf G,Mrozik K,Heuck CC,Middelhoff G,Oster P,Riesen W,Schellenberg B

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Cell adhesion molecules (CAMs) are implicated in the initiation and progression of atherosclerosis, but their association with risk of type 2 diabetes remains inconsistent. This meta-analysis aimed to quantify this association with dose-response analysis in the general population without type 2 diab...

journal_title：Atherosclerosis

authors： Qiu S,Cai X,Liu J,Yang B,Zügel M,Steinacker JM,Sun Z,Schumann U

更新日期：2019-08-01 00:00:00

abstract：:An organ culture technique was used to investigate the removal of fatty acids incorporated into various lipid fractions in intimal segments of atherosclerotic rabbit aorta. Segments of aorta were pulse-labelled in vitro with [9,10-3H]oleic acid and [1-14C]linoleic acid for 24 h. The incubation medium was replaced with...

journal_title：Atherosclerosis

authors： Hudson K,Day AJ,Horsch AK

更新日期：1977-12-01 00:00:00

abstract：:HMG-CoA reductase inhibitor drugs or 'statins' have been shown to effectively reduce plasma total cholesterol (CHOL), CHOL associated with low-density-lipoprotein (LDL), and triglycerides (TG). In addition, slight elevations in HDL-CHOL are also typically observed. Poloxamer 407 (P-407), a nonionic surfactant, effecti...

journal_title：Atherosclerosis

authors： Johnston TP,Baker JC,Hall D,Jamal S,Palmer WK,Emeson EE

更新日期：2000-04-01 00:00:00

abstract：:The dose-response effects of clofibrate and niceritrol on serum cholesterol and triglycerides (TG) were studied in 29 patients with Type IIa and IIb hyperlipoproteinaemia. In 17 patients, clofibrate and niceritrol were then given as combined treatment, and the effects of this combination on serum lipoproteins were stu...

journal_title：Atherosclerosis

authors： Olsson AG,Orö L,Rössner S

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:The influence of hepatitis C virus (HCV) infection on atherosclerosis risk in HIV-infected patients has not been adequately evaluated in real-life situations. OBJECTIVES AND METHODS:We compared indexes of early atherosclerosis evaluated by echo-Doppler ultrasound (presence of plaque in carotid or femoral ar...

journal_title：Atherosclerosis

authors： Sosner P,Wangermez M,Chagneau-Derrode C,Le Moal G,Silvain C

更新日期：2012-05-01 00:00:00

abstract：AIM:The present clinical study tested the hypothesis that oil-rich fish consumption improves CHD risk factors. METHODS:Forty-eight (16 men) non-obese, healthy adults aged 20-55, consumed 125 g/day of salmon for a 4-week period followed by a 4-week period with no-fish (41 completers). Subjects were instructed to mainta...

journal_title：Atherosclerosis

authors： Lara JJ,Economou M,Wallace AM,Rumley A,Lowe G,Slater C,Caslake M,Sattar N,Lean ME

更新日期：2007-07-01 00:00:00

abstract：:Investigations to date have demonstrated that the underlying etiology, causes and burden of stroke may be different for women and men. However, data regarding sex differences among young cerebral ischemic stroke patients remains scarce. We conducted this study in 669 young Chinese adults with acute ischemic stroke as ...

journal_title：Atherosclerosis

authors： Zhang B,Pu S,Zhang W,Yang N,Shen G,Yin J,Yi Y,Gao Q,Gao C

更新日期：2011-06-01 00:00:00

abstract：:Elevated serum ferritin concentrations between 200 and 500 microg/l have been found to be a strong risk factor for acute myocardial infarction in Finnish men, but the reason for this association is still uncertain. In the Finnish population ferritin concentrations correlated with factors of insulin resistance syndrome...

journal_title：Atherosclerosis

authors： Halle M,König D,Berg A,Keul J,Baumstark MW

更新日期：1997-02-10 00:00:00

abstract：:The ability of triglyceride (TG)-rich lipoproteins from apolipoprotein (apo) E2 heterozygote, apo E3/2 which is relatively common, to stimulate cholesteryl ester synthesis in human monocyte-derived macrophages was studied to clarify the atherogenicity of apo E3/2. Twenty-three subjects were randomly sampled from our h...

journal_title：Atherosclerosis

authors： Saito M,Eto M,Makino I

更新日期：1997-02-28 00:00:00

abstract：OBJECTIVE:The objective of the present study was to investigate the effects of one-year treatment with exenatide or Insulin Glargine, followed by a 5-week off-drug period, on postprandial lipidaemia, glycaemia and measures of oxidative stress. METHODS:Sixty-nine metformin-treated patients with type 2 diabetes were ran...

journal_title：Atherosclerosis

authors： Bunck MC,Cornér A,Eliasson B,Heine RJ,Shaginian RM,Wu Y,Yan P,Smith U,Yki-Järvinen H,Diamant M,Taskinen MR

更新日期：2010-09-01 00:00:00

abstract：:Five out of 15 homozygotes and 41 out of 527 heterozygotes of familial hypercholesterolemia (FH) died during the past 10 years. Sudden death or heart failure was the cause of death in each of the 5 deceased homozygotes. Twenty heterozygotes died of myocardial infarction, 9 of sudden death, and 1 died after AC bypass s...

journal_title：Atherosclerosis

authors： Mabuchi H,Miyamoto S,Ueda K,Oota M,Takegoshi T,Wakasugi T,Takeda R

更新日期：1986-07-01 00:00:00