Sex differences in risk factors, etiology, and short-term outcome of cerebral infarction in young patients.

abstract：BACKGROUND:The influence of hepatitis C virus (HCV) infection on atherosclerosis risk in HIV-infected patients has not been adequately evaluated in real-life situations. OBJECTIVES AND METHODS:We compared indexes of early atherosclerosis evaluated by echo-Doppler ultrasound (presence of plaque in carotid or femoral ar...

journal_title：Atherosclerosis

authors： Sosner P,Wangermez M,Chagneau-Derrode C,Le Moal G,Silvain C

更新日期：2012-05-01 00:00:00

abstract：:Angiotensin converting enzyme 2 (ACE2) is a homolog of angiotensin converting enzyme (ACE) which generates angiotensin II from angiotensin I. ACE, its product angiotensin II and the downstream angiotensin type I receptor are important components of the renin-angiotensin system (RAS). Angiotensin II, the most important...

journal_title：Atherosclerosis

authors： Wang Y,Tikellis C,Thomas MC,Golledge J

更新日期：2013-01-01 00:00:00

abstract：:Familial ligand-defective apolipoprotein (apo) B-100 (FDB) is an autosomal codominant disorder which may give rise to hypercholesterolaemia. It is caused by the substitution of glutamine for arginine at codon 3500 of the apo B gene (apo B R3500Q), resulting in decreased binding of low density lipoprotein (LDL) to the ...

journal_title：Atherosclerosis

authors： Wenham PR,Henderson BG,Penney MD,Ashby JP,Rae PW,Walker SW

更新日期：1997-03-21 00:00:00

abstract：:SR-12813 inhibits cholesterol biosynthesis in Hep G2 cells via an enhanced degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Here we also show that SR-12813 inhibits cholesterol biosynthesis in vivo. A sterol balance study was performed in normolipemic beagle dogs. The dogs were given SR-12813 ...

journal_title：Atherosclerosis

authors： Berkhout TA,Simon HM,Jackson B,Yates J,Pearce N,Groot PH,Bentzen C,Niesor E,Kerns WD,Suckling KE

更新日期：1997-09-01 00:00:00

abstract：:Lipid and apoprotein composition of four very low density lipoprotein (VLDL) subfractions decreasing in Sf value were evaluated in the fasting state in 12 normolipidemic Pima Indians (6 M, 6 F, age 39 +/- 1.7 yrs) (mean +/- SEM) with non-insulin-dependent diabetes mellitus (NIDDM) in poor glycemic control (HbA1 9.8 +/...

journal_title：Atherosclerosis

authors： Patti L,Swinburn B,Riccardi G,Rivellese AA,Howard BV

更新日期：1991-11-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) refers to a group of positional and geometric isomers of linoleic acid and has been shown to suppress the development of atherosclerosis in experimental models. However, the mechanism involved is unclear although it is believed it may act as a cyclooxygenase inhibitor or as an agonist of...

journal_title：Atherosclerosis

authors： Toomey S,Harhen B,Roche HM,Fitzgerald D,Belton O

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To evaluate whether higher circulating levels of complement proteins C3 and C4 are associated with menopausal status and with hemostatic/thrombus formation markers (circulating factor VII (factor VIIc), fibrinogen, plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator antigen (tPA-ag)) in...

journal_title：Atherosclerosis

authors： El Khoudary SR,Shields KJ,Chen HY,Matthews KA

更新日期：2013-11-01 00:00:00

abstract：:Atherosclerotic plaque rupture and erosions precipitate thrombus formation and may lead to an acute ischemic syndrome. Lipids and lipoproteins modulate the expression and/or function of thrombotic, fibrinolytic and rheologic factors, and thereby influence hemostasis and potential tissue damage resulting from vascular ...

journal_title：Atherosclerosis

authors： Rosenson RS,Lowe GD

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Fenofibrate, a PPAR-α agonist and rosiglitazone, a PPAR-γ agonist, reduce triglycerides and fatty acids in humans and in animal disease models. The efficacy of PPAR-α agonists in mouse model of human atherosclerosis disease has shown mixed results, and efficacy of PPAR-γ and liver X receptor (LXR) agonists h...

journal_title：Atherosclerosis

authors： Srivastava RA

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Matrix metalloproteinases (MMPs) are implicated in the pathogenesis of atherosclerosis. However, the relationship between blood levels of MMPs and the extent of carotid atherosclerosis remains uncertain. We assessed blood levels of active MMPs in relation to the extent of carotid plaque formation and intima-m...

journal_title：Atherosclerosis

authors： Lien LM,Hsieh YC,Bai CH,Chen WH,Chiu HC,Hsieh FI,Shyu KG,Chiou HY,Hsu CY

更新日期：2010-10-01 00:00:00

abstract：:Estrogen use is associated with protection from cardiovascular disease in postmenopausal women. This benefit appears to be magnified among women with pre-existing heart disease. The possible bias of intrinsically better health in women using estrogen has not been ruled out in observational studies. Therefore, two doub...

journal_title：Atherosclerosis

authors： Knopp RH,Zhu X,Bonet B

更新日期：1994-10-01 00:00:00

abstract：:Prolonged exposure of rats to cigarette smoke resulted in significant alterations in the metabolism of lipids. There was a significant increase in the concentration of cholesterol, triglycerides and phospholipids in most of the tissues, particularly the heart, aorta and lungs. Cholesterol, triglycerides and phospholip...

journal_title：Atherosclerosis

authors： Latha MS,Vijayammal PL,Kurup PA

更新日期：1988-04-01 00:00:00

abstract：:The aim of this review was to bring together results obtained from studies on different aspects of HDL as related to CHD and atherosclerosis. As atherosclerosis is a multistep process, the various components of HDL can intervene at different stages, such as induction of monocyte adhesion molecules, prevention of LDL m...

journal_title：Atherosclerosis

authors： Stein O,Stein Y

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Clinical interventions targeting nonlipid risk factors are needed given the high residual risk of atherothrombotic events despite effective control of dyslipidemia. Dickkopf-1 (DKK1) plays a lipid-independent role in vascular pathophysiology but its involvement in atherosclerosis development and its...

journal_title：Atherosclerosis

authors： Rakipovski G,Rolin B,Barascuk N,Lund HE,Bjørn Bonde MF,Djordjevic D,Wulff-Larsen PG,Petersen M,Kirk RK,Hultman K,Manfe V,Blume N,Zahn S,Lengquist M,Maegdefessel L,Hovingh GK,Conde-Knape K,Hedin U,Matic L,Nyberg M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Low ankle-brachial index (ABI) calculated using systolic blood pressure (SBP) is associated with poor prognosis. However, there is no study assessing ABI calculated using mean artery pressure (MAP) and diastolic blood pressure (DBP) in predicting mortality. METHODS:Two cohort populations were enrol...

journal_title：Atherosclerosis

authors： Hsu PC,Lee WH,Chen YC,Lee MK,Tsai WC,Chu CY,Lee CS,Yen HW,Lin TH,Voon WC,Lai WT,Sheu SH,Su HM

更新日期：2020-07-01 00:00:00

abstract：:The ultrastructure of the aortic intima and serum lipid levels in Fischer 344 rats were examined at the ages of 12, 18 and 24 months after feeding the animals an atherogenic diet (2% cholesterol, 0.25% sodium cholate, 5% beef fat) for 6 months. Structural changes in the intima were noticeable only at the age of 24 mon...

journal_title：Atherosclerosis

authors： Nakamura H,Izumiyama N,Nakamura K,Ohtsubo K

更新日期：1989-10-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) has been proposed as a potential tool in the evaluation of atherosclerotic lesions. However, two basic difficulties have to date prevented the full exploitation of the potentials of this technique: the poor spatial resolution of the conventional tomographs and the wide variety of the l...

journal_title：Atherosclerosis

authors： Asdente M,Pavesi L,Oreste PL,Colombo A,Kuhn W,Tremoli E

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To investigate whether atherosclerosis can be prevented by magnetically labeled endothelial progenitor cells (EPCs) in rabbits. MATERIALS AND METHODS:EPCs derived from rabbit periphery blood were labeled with a superparamagnetic iron oxide (SPIO) agent Fe(2)O(3)-poly-L-lysine (Fe(2)O(3)-PLL). Rabbit atheroscle...

journal_title：Atherosclerosis

authors： Ma ZL,Mai XL,Sun JH,Ju SH,Yang X,Ni Y,Teng GJ

更新日期：2009-07-01 00:00:00

abstract：:Studies were performed to determine if serum bilirubin, when combined with various lipid and lipoprotein risk factors, enhances our ability to predict coronary artery disease (CAD). This hypothesis was tested in a retrospective study of 644 middle-aged males who had undergone coronary angiography. The traditional risk...

journal_title：Atherosclerosis

authors： Schwertner HA,Fischer JR Jr

更新日期：2000-06-01 00:00:00

abstract：:While statin treatment may transiently mobilize endothelial progenitor cells (EPCs), the dose-dependent effects of a continuous statin therapy on EPCs in patients with chronic coronary artery disease (CAD) have not been analyzed. In 209 patients with angiographically documented CAD, 144 of which received 10-40 mg/day ...

journal_title：Atherosclerosis

authors： Hristov M,Fach C,Becker C,Heussen N,Liehn EA,Blindt R,Hanrath P,Weber C

更新日期：2007-06-01 00:00:00

abstract：:Connective tissue growth factor (CTGF) is expressed in atherosclerotic plaques. It is generally recognized that CTGF contributes to atherosclerosis by stimulating vascular smooth muscle cell (VSMC) proliferation and extracellular matrix production during the development of atherosclerosis. Recent studies indicate that...

journal_title：Atherosclerosis

authors： Game BA,He L,Jarido V,Nareika A,Jaffa AA,Lopes-Virella MF,Huang Y

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Adiponectin is one of several important, metabolically active cytokines secreted from adipose tissue. Epidemiologic studies have associated low circulating levels of this adipokine with multiple metabolic disorders including obesity, insulin resistance, type II diabetes, and cardiovascular disease. To investi...

journal_title：Atherosclerosis

authors： Luo N,Chung BH,Wang X,Klein RL,Tang CK,Garvey WT,Fu Y

更新日期：2013-05-01 00:00:00

abstract：:Platelet phospholipid composition was analyzed before and after extracorporeal removal of low density lipoproteins (LDL) by LDL apheresis in six patients with familial hypercholesterolemia. Elevated levels of total plasma cholesterol and the portion of plasma cholesterol carried by LDL were reduced by 56 and 66% after...

journal_title：Atherosclerosis

authors： Bräutigam R,Bräutigam C,Lorenz R,Richter WO,Engelmann B

更新日期：1997-05-01 00:00:00

abstract：:The well established 'systemic' risk factors for atherosclerosis can explain only half of the variability in its occurrence. To account for some of the remaining variability, it was suggested that certain geometric features of atherosclerosis-prone segments ('geometric risk factors') can increase the likelihood of dis...

journal_title：Atherosclerosis

authors： Friedman MH,Baker PB,Ding Z,Kuban BD

更新日期：1996-09-06 00:00:00

abstract：UNLABELLED:Pentraxin 3 (PTX3) is an acute phase protein strongly expressed by advanced atherosclerotic lesions. We investigated (a) PTX3 expression and secretion in subcutaneous adipose tissue (SAT) and omental visceral adipose tissue (VAT) obtained from 21 obese (37.4+/-8.15 yr) and 10 normal weight subjects (43.7+/-1...

journal_title：Atherosclerosis

authors： Alberti L,Gilardini L,Zulian A,Micheletto G,Peri G,Doni A,Mantovani A,Invitti C

更新日期：2009-02-01 00:00:00

abstract：:This paper reports the results of the largest autopsy-based comparative study of atherosclerotic lesions between young Japanese and Americans, aged 15-34 years and autopsied between 1987 and 1995, by analyzing the data from the Japanese second nation-wide study of atherosclerosis and Pathobiological Determinants of At...

journal_title：Atherosclerosis

authors： Takei H,Strong JP,Yutani C,Malcom GT

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Allergic asthma can accelerate atherosclerosis, a disease in which plaque is deposited onto arterial walls and that may lead to coronary artery disease (CAD). Eosinophils are the most important effector cells in allergic asthma and are likely to become novel biomarkers for risk stratification of pat...

journal_title：Atherosclerosis

authors： Gao S,Deng Y,Wu J,Zhang L,Deng F,Zhou J,Yuan Z,Wang L

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MS) is associated with dyslipidemia, and insulin resistance (IR) may be a main determinant of this dyslipidemia. OBJECTIVE:To determine how lipoprotein particle concentration and size are related to MS and IR in a population-based sample of Alaska Eskimos. DESIGN:Participants underwent ...

journal_title：Atherosclerosis

authors： Rivellese AA,Patti L,Kaufman D,Zhu J,Annuzzi G,Vaccaro O,Ebbesson SO,Howard WJ,Riccardi G,Howard BV

更新日期：2008-10-01 00:00:00

abstract：AIMS:We have examined the cross-sectional relationship between insulin resistance, the metabolic syndrome and haemostatic and inflammatory markers. METHODS AND RESULTS:We carried out the study in 2722 non-diabetic men aged 60-79 years with no history of coronary heart disease or stroke and who were not on warfarin tre...

journal_title：Atherosclerosis

authors： Wannamethee SG,Lowe GD,Shaper AG,Rumley A,Lennon L,Whincup PH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Recent studies suggest that long-term endurance training may be damaging to the heart, thus increasing cardiovascular disease (CVD) risk. However, studies utilizing cardiac imaging are conflicting and lack measures of central and peripheral vascular structure and function, which are also independent...

journal_title：Atherosclerosis

authors： Bachman NP,Terwoord JD,Richards JC,Braun B,Green CP,Luckasen GJ,Dinenno FA

更新日期：2020-12-01 00:00:00