Perinatal exposure to methadone affects central cholinergic activity in the weanling rat.

abstract：:The rearrest rates among Norwegian drugged (n=1102) and a group of drunken drivers (n=850) (BAC: 0.16-0.19%) apprehended during 1992, were 57% (n=629) and 28% (n=238), respectively, when followed prospectively for 7 years. The most important risk factors for recidivism among drugged drivers were previous arrests for d...

journal_title：Drug and alcohol dependence

authors： Christophersen AS,Skurtveit S,Grung M,Mørland J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:This study integrates data from high-quality mental health surveys in five provinces in China to examine the prevalence, demographic correlates, age of onset, and comorbidity of alcohol use disorder (AUD). METHODS:The five cross-sectional surveys initially screened a representative sample of 74,752 communit...

journal_title：Drug and alcohol dependence

authors： Phillips MR,Cheng HG,Li X,Zhang J,Shi Q,Xu G,Song Z,Ding Z,Pang S

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Laboratory studies in which drugs of abuse are self- or experimenter-administered to non-treatment-seeking research volunteers provide valuable data about new pharmacotherapies for substance use disorders, as well as behavioral and performance data for understanding the neurobiology of drug abuse. This paper ...

journal_title：Drug and alcohol dependence

authors： Kalapatapu RK,Bedi G,Haney M,Evans SM,Rubin E,Foltin RW

更新日期：2012-01-01 00:00:00

abstract：:Sequence of drug use was examined in a secondary analysis of two samples of serious drug users: one of 152 men and one of 133 women. The proportions of drug users following specified patterns of drug use onset were compared to proportions obtained in previous research in samples of high school youth, and serious drug ...

journal_title：Drug and alcohol dependence

authors： Mackesy-Amiti ME,Fendrich M,Goldstein PJ

更新日期：1997-05-02 00:00:00

abstract：BACKGROUND:The theoretical benefits of naltrexone as a treatment for opioid use disorder (e.g., safety, non-addictive, low risk of diversion) stand in sharp contrast to its disappointing record on retention in most samples. The relationship of uncomfortable physical and dysphoric symptoms to retention on naltrexone is ...

journal_title：Drug and alcohol dependence

authors： Carroll KM,Nich C,Frankforter TL,Yip SW,Kiluk BD,DeVito EE,Sofuoglu M

更新日期：2018-11-01 00:00:00

abstract：:Male rats were given ethanol via an intragastric catheter (8.0-11.0 g/kg per day) for either 8 weeks daily or for four 2-week periods with a 2-week period of no drug treatment intervening between each period of ethanol administration (binge). Older rats were administered ethanol for 2 weeks, to assess the effects of a...

journal_title：Drug and alcohol dependence

authors： Maier DM,Pohorecky LA

更新日期：1989-04-01 00:00:00

abstract：AIMS:1) To confirm the association between delay for assessment (DFA) and probability of first-time attendance in outpatient substance use disorder (SUD) treatment. 2) To evaluate whether this association varies by the type of primary substance for which the assessment was requested. 3) To assess the possibility of est...

journal_title：Drug and alcohol dependence

authors： Simioni N,Rolland B,Labreuche J,Ramdane N,Cottencin O

更新日期：2016-09-01 00:00:00

abstract：:The drug habits for 78 confirmed opiate addicts were studied on eight scales from the Process Association Test of Addiction (PATA) for many drug names. Through cluster analysis eight stages of addiction were defined: "to be clean", "to learn about drugs", "to hustle", "to chip" (also "to be high"), to be psychological...

journal_title：Drug and alcohol dependence

authors： Haertzen CA,Ross FE

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:This paper explores the magnitude of--and extent of overlap between--additive genetic, shared environmental and non-shared environmental influences on lifetime stimulant use and on stimulant abuse/dependence symptoms; the associations between stimulant use and cannabis use and the extent to which these assoc...

journal_title：Drug and alcohol dependence

authors： Lynskey MT,Grant JD,Li L,Nelson EC,Bucholz KK,Madden PA,Statham D,Martin NG,Heath AC

更新日期：2007-01-12 00:00:00

abstract：:This study examined the extent to which social relationships were associated with continued injection drug use and needle sharing among 252 methadone maintenance patients. Logistic regression analyses indicated that drug use was highest among persons who had a substance using live-in partner and among those with more ...

journal_title：Drug and alcohol dependence

authors： Gogineni A,Stein MD,Friedmann PD

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Cannabis withdrawal is not recognized in DSM-IV because of doubts about its clinical significance. OBJECTIVES:Assess the phenomenon of cannabis withdrawal and its relationship to relapse in non-treatment-seeking adults. SUBJECTS:Convenience sample of 469 adult cannabis smokers who had made a quit attempt w...

journal_title：Drug and alcohol dependence

authors： Levin KH,Copersino ML,Heishman SJ,Liu F,Kelly DL,Boggs DL,Gorelick DA

更新日期：2010-09-01 00:00:00

abstract：:Cerebral spinal fluid (CSF) levels of methadone were measured in nine methadone maintenance patients requiring lumbar punctures for medical or surgical treatment. Concurrent serum methadone levels were also determined. The CSF concentration of methadone in all cases was a fraction of the corresponding serum level--ran...

journal_title：Drug and alcohol dependence

authors： Rubenstein RB,Kreek MJ,Mbawa N,Wolff WI,Korn R,Gutjahr CL

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Despite calls for non-abstinence endpoints in randomized clinical trials (RCTs) for cocaine use disorder, there is a lack of data validating non-abstinence endpoints. We conducted a clinical validation of reduction in cocaine frequency level as a non-abstinence endpoint in RCTs for cocaine use disorder (CUD)...

journal_title：Drug and alcohol dependence

authors： Roos CR,Nich C,Mun CJ,Babuscio TA,Mendonca J,Miguel AQC,DeVito EE,Yip SW,Witkiewitz K,Carroll KM,Kiluk BD

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Despite harmful consequences of drug addiction, it is common for individuals with substance use disorders to deny having problems with drugs. Emerging evidence suggests that some drug users lack insight into their behavior due to neurocognitive dysfunction, but little research has examined potential neurocog...

journal_title：Drug and alcohol dependence

authors： Dean AC,Kohno M,Morales AM,Ghahremani DG,London ED

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:A number of studies have researched the association between monoamine oxidase gene (MAO) polymorphisms and smoking behavior, but the conclusion is quite inconsistent. A meta-analysis was conducted to assess the association of MAO-A C1460T, MAO-A VNTR and MAO-B G644A polymorphisms with smoking behavior. METH...

journal_title：Drug and alcohol dependence

authors： Yang X,Chen H,Li S,Wang Q,Pan L,Jia C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:This study examined the relative impact of familial and non-familial smoking on participant smoking and nicotine dependence. METHODS:This is a longitudinal study of 838 African American and Puerto Rican participants who were interviewed four times in their homes over a 15-16-year period (1990, 1994-1996, 20...

journal_title：Drug and alcohol dependence

authors： Brook JS,Saar NS,Zhang C,Brook DW

更新日期：2009-04-01 00:00:00

abstract：:The prevalence of smoking among alcohol abusers is high, yet little is known about this dual-dependency. This study examines mechanisms involved in changing both alcohol and tobacco use concurrently using the transtheoretical model (TTM) measures of change. Alcohol and tobacco dependent outpatients (N=115) entering a ...

journal_title：Drug and alcohol dependence

authors： Stotts AL,Schmitz JM,Grabowski J

更新日期：2003-01-24 00:00:00

abstract：:This double-blind, randomized, placebo-controlled clinical trial evaluated the impact on withdrawal symptoms of (i) combining naltrexone with a 4-day buprenorphine taper for short opioid detoxification (NB Group), compared to (ii) using a 4-day buprenorphine taper alone, followed by naltrexone on day 8 (PB Group). Sub...

journal_title：Drug and alcohol dependence

authors： Umbricht A,Montoya ID,Hoover DR,Demuth KL,Chiang CT,Preston KL

更新日期：1999-10-01 00:00:00

abstract：:In a study of the effect of 26 psychoactive drugs on the complex of mouse behaviour changes caused by acetaldehyde it was found that tranquillizers, hypnotics, sodium oxybutyrate and ethanol are the most efficient. The differences in teh drug effects were determined by a tan alpha criterion. Antidepressants and neurol...

journal_title：Drug and alcohol dependence

authors： Andronova LM,Barkov NK

更新日期：1981-09-01 00:00:00

abstract：OBJECTIVE:To characterize patterns and correlates of inhalant use among incarcerated youth. METHOD:Residents (N=723) of 27 Missouri Division of Youth Services facilities completed interviews assessing substance use, psychiatric symptoms, antisocial traits, trauma, suicidality, and criminality. RESULTS:Participants av...

journal_title：Drug and alcohol dependence

authors： Howard MO,Balster RL,Cottler LB,Wu LT,Vaughn MG

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Although the prevalence of alcohol use disorders (AUDs) has increased in older individuals in the recent decade, there are few programs to mitigate that increase. The current analyses evaluate the feasibility of applying to older drinkers elements of an approach to prevent heavier drinking in young adults by...

journal_title：Drug and alcohol dependence

authors： Schuckit MA,Smith TL

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Drug overdose deaths have risen precipitously over the last fifteen years. Substantial geographic variation, beyond a simple rural-urban dichotomy, exists in the concentration of overdose deaths, suggesting the existence of as-yet unidentified environmental variables that predict resilience (or vulnerability...

journal_title：Drug and alcohol dependence

authors： Zoorob MJ,Salemi JL

更新日期：2017-04-01 00:00:00

abstract：:Exposure to self-administered drugs is sufficient to produce drug-seeking in animal models. In many cases priming injections of drugs that share discriminative stimulus properties with the self-administered drug also can lead to drug-seeking, suggesting that exposure might precipitate relapse. The present investigatio...

journal_title：Drug and alcohol dependence

authors： Schenk S,Hely L,Gittings D,Lake B,Daniela E

更新日期：2008-08-01 00:00:00

abstract：:A large number of studies have given clear indications that ethanol does affect the physicochemical properties of the membrane. Membrane reorganization and adaptation can develop against the acute disordering effect of ethanol during chronic intoxication. Nevertheless, there has been so far no direct evidence of corre...

journal_title：Drug and alcohol dependence

authors： Beaugé F,Aufrère G,Niel E,Zérouga M,Le Bourhis B

更新日期：1990-02-01 00:00:00

abstract：:It is argued that studying the drinking patterns of adolescents can add much to our understanding of alcohol use. The present paper hypothesises that heavy drinkers will be experiencing more stress than light, moderate or non-drinkers and that consequently, they will perceive themselves as doing worse in school and wi...

journal_title：Drug and alcohol dependence

authors： Budd RJ,Eiser JR,Morgan M,Gammage P

更新日期：1985-11-01 00:00:00

abstract：:A single dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. This effect is probably mediated through effects of ethanol on acetylcholine release. Choline uptake has also been shown to be altered in ethanol-dependent animals, and these effects may be coupled to alterat...

journal_title：Drug and alcohol dependence

authors： Hunt WA,Majchrowicz E

更新日期：1979-05-01 00:00:00

abstract：:Premature termination of treatment by the client has been a pervasive problem in the alcohol treatment field. This drop-out problem is compounded in conjoint therapy for alcoholic couples since most clients typically do not view the drinking problem from a systemic, interactional perspective. Within a short-term commu...

journal_title：Drug and alcohol dependence

authors： Zweben A,Pearlman S,Li S

更新日期：1983-06-01 00:00:00

abstract：:In a sample survey of 712 Iranian male adolescents, aged 14-18, it was found that drugs users differed in only some of theirs beliefs about drug substances and their use from their non-drug-using contemporaries; and that both sub-samples had, in their agreement about the drug problem in post-revolutionary Iran, been e...

journal_title：Drug and alcohol dependence

authors： Agahi C,Spencer C

更新日期：1982-10-01 00:00:00

abstract：INTRODUCTION:Smoking prevalence among those in substance misuse treatment remains much higher than the general population, despite evidence for effective cessation interventions that do not negatively impact substance misuse outcomes. This systematic review summarises qualitative data on barriers and facilitators to sm...

journal_title：Drug and alcohol dependence

authors： Gentry S,Craig J,Holland R,Notley C

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Social impairments are important features of a substance use disorder diagnosis; and recent models suggest early impairments in socio-cognitive and -affective processes may predict future use. However, no systematic reviews are available on this topic. METHODS:We conducted a systematic review and meta-analy...

journal_title：Drug and alcohol dependence

authors： Winters DE,Brandon-Friedman R,Yepes G,Hinckley JD

更新日期：2021-02-01 00:00:00