当前位置： SCI文献检索 > DRUG AND ALCOHOL DEPENDENCE期刊下所有文献 > Mediation of effects of the level of response to alcohol and impulsivity 15 years later in 36-year-old men: Implications for prevention efforts.

Mediation of effects of the level of response to alcohol and impulsivity 15 years later in 36-year-old men: Implications for prevention efforts.

Abstract：

BACKGROUND:Although the prevalence of alcohol use disorders (AUDs) has increased in older individuals in the recent decade, there are few programs to mitigate that increase. The current analyses evaluate the feasibility of applying to older drinkers elements of an approach to prevent heavier drinking in young adults by focusing on mediators of effects of two risk factors for alcohol problems, low levels of response to alcohol (low LRs) and higher impulsivity. METHODS:Data were extracted from the San Diego Prospective Study (SDPS). Structural Equation Models evaluated relationships among age 36 low LRs and higher impulsivity; age 46 perceived peer drinking, alcohol expectancies, and drinking to cope; and age 51 alcohol problems, even after controlling for age 36 alcohol problems. RESULTS:Relationships of age 36 low LRs to later alcohol problems was both direct and linked to age 46 heavy drinking peers. LR also operated indirectly through peer drinking to alcohol expectancies and drinking to cope. Age 36 impulsivity had no direct path to later alcohol problems and operated primarily through mediation by alcohol expectancies and via expectancies to drinking to cope. After controlling for age 36 alcohol problems, the low LR and impulsivity results remained robust. CONCLUSIONS:Programs for mitigating increases in alcohol problems in middle-age drinkers should consider identifying individuals with low LRs and/or higher impulsivity and implementing prevention approaches similar to a program used in young adults. The approach should emphasize some different mediators for older drinkers with low LRs and those with higher impulsivity.

journal_name

Drug Alcohol Depend

journal_title

Drug and alcohol dependence

authors

Schuckit MA,Smith TL

doi

10.1016/j.drugalcdep.2017.08.030

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

356-362

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(17)30471-4

journal_volume

180

pub_type

杂志文章

相关文献

DRUG AND ALCOHOL DEPENDENCE文献大全
  • Stimulant use and symptoms of abuse/dependence: epidemiology and associations with cannabis use--a twin study.

    abstract：BACKGROUND:This paper explores the magnitude of--and extent of overlap between--additive genetic, shared environmental and non-shared environmental influences on lifetime stimulant use and on stimulant abuse/dependence symptoms; the associations between stimulant use and cannabis use and the extent to which these assoc...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2006.05.023

    authors： Lynskey MT,Grant JD,Li L,Nelson EC,Bucholz KK,Madden PA,Statham D,Martin NG,Heath AC

    更新日期：2007-01-12 00:00:00

  • Barriers to seeking help for physicians with substance use disorder: A review.

    abstract：BACKGROUND:Substance use disorders (SUD) might concern as many as 8-15% of physicians. Previous studies suggest that self-diagnosis and self-medication are common practices among physicians. The aim of this review was to identify if barriers to seeking help and medical care for impaired physicians exist. We also aimed ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,评审

    doi：10.1016/j.drugalcdep.2019.04.004

    authors： Vayr F,Herin F,Jullian B,Soulat JM,Franchitto N

    更新日期：2019-06-01 00:00:00

  • Drinking and driving among American youth: beliefs and behaviors.

    abstract：:Data from research on traffic accident populations clearly indicate that a large proportion of accidents involve drivers under the age of twenty-five. Even after differential exposure to traffic accidents has been controlled for, young drivers remain over-represented in both alcohol-related and non-alcohol-related tra...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(82)90084-9

    authors： Cameron TL

    更新日期：1982-09-01 00:00:00

  • Gender and nonmedical prescription opioid use and DSM-5 nonmedical prescription opioid use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions - III.

    abstract：BACKGROUND:Little is known about sex-specific risk for nonmedical prescription opioid use (NMPOU) and DSM-5 nonmedical prescription opioid use disorder (NMPOUD). The objective of the present study was to present prevalence, correlates, psychiatric comorbidity, treatment and disability of NMPOU and DSM-5 NMPOUD among me...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2015.08.026

    authors： Kerridge BT,Saha TD,Chou SP,Zhang H,Jung J,Ruan WJ,Smith SM,Huang B,Hasin DS

    更新日期：2015-11-01 00:00:00

  • The relationship between recreational gambling and substance abuse/dependence: data from a nationally representative sample.

    abstract：BACKGROUND:Although recreational gambling is prevalent and co-occurs with substance abuse/dependence, few studies have investigated the relationship between the two. METHODS:Logistic regression analyses were performed on data from a nationally representative sample from the Gambling Impact and Behavior Study. RESULTS...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2008.09.011

    authors： Liu T,Maciejewski PK,Potenza MN

    更新日期：2009-02-01 00:00:00

  • Introduction to the College on Problems of Drug Dependence special issue: contemporary advances in opioid neuropharmacology.

    abstract：:Opioid receptors are critical therapeutic targets for medications development relevant to the treatment of drug dependence and pain. With recent advances in molecular neurobiology, it has become evident that the functional activity of opioid receptors, as ligand-regulated protein complexes, is modulated by multifariou...

    journal_title：Drug and alcohol dependence

    pub_type： 社论

    doi：10.1016/j.drugalcdep.2010.03.001

    authors： Walsh SL,Unterwald EM,Izenwasser S

    更新日期：2010-05-01 00:00:00

  • Formulation considerations for the development of medications with abuse potential.

    abstract：:The availability of increasingly sophisticated drug formulations and delivery devices has created new opportunities in drug development. These newer approaches can result in improved drug bioavailability, or they can alter key pharmacokinetic parameters in such a way as to decrease dosing interval, decrease variabilit...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2005.10.018

    authors： Mansbach RS,Moore RA Jr

    更新日期：2006-06-01 00:00:00

  • Implementation of online opioid overdose prevention, recognition and response trainings for professional first responders: Year 1 survey results.

    abstract：BACKGROUND:This article reports on the first web-based implementation of an opioid-overdose prevention, recognition and response training for professional first responders. The training was disseminated nationally over one listserv in November 2014. The same year, following Act 139, which mandated the provision of an o...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2016.10.003

    authors： Simmons J,Rajan S,Goldsamt L,Elliott L

    更新日期：2016-12-01 00:00:00

  • An overview of the emergence of disparities in smoking prevalence, cessation, and adverse consequences among women.

    abstract：:This report reviews epidemiologic findings demonstrating the emergence of disparities in smoking prevalence against the backdrop of general declines in smoking over time among women in the United States. In addition to socioeconomic differences in overall smoking prevalence, this report examines evidence of emerging d...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,评审

    doi：10.1016/j.drugalcdep.2009.06.002

    authors： Chilcoat HD

    更新日期：2009-10-01 00:00:00

  • Mechanisms of change in extended cognitive behavioral treatment for tobacco dependence.

    abstract：AIM:To evaluate potential mediators of an extended cognitive behavioral smoking cessation intervention. DESIGN:Analysis of data from a randomized clinical trial of smoking cessation. SETTING:The Habit Abatement Clinic, University of California, San Francisco. PARTICIPANTS:Participants were older cigarette smokers (>...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2009.12.021

    authors： Hendricks PS,Delucchi KL,Hall SM

    更新日期：2010-06-01 00:00:00

  • Antecedents and correlates of methadone treatment entry: a comparison of out-of-treatment and in-treatment cohorts.

    abstract：BACKGROUND:The majority of opioid-dependent individuals in the US in need of drug treatment are not receiving it. It would be useful to understand the characteristics of individuals entering and failing to enter methadone treatment. METHODS:Participants were opioid-dependent adults in Baltimore Maryland recruited from...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2010.10.016

    authors： Schwartz RP,Kelly SM,O'Grady KE,Mitchell SG,Brown BS

    更新日期：2011-05-01 00:00:00

  • Metabolic phenotype of rats exposed to heroin and potential markers of heroin abuse.

    abstract：BACKGROUND:Metabolomics allows the high-throughput analysis of low molecular mass compounds in biofluids, which can reflect the metabolic response of the body to heroin exposure and potentially reveal biomarkers of heroin abuse. METHODS:Heroin was administered to Sprague-Dawley rats in increasing doses from 3 to 16.5 ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2012.06.031

    authors： Zheng T,Liu L,Aa J,Wang G,Cao B,Li M,Shi J,Wang X,Zhao C,Gu R,Zhou J,Xiao W,Yu X,Sun R,Zhou Y,Zuo Y,Zhu X

    更新日期：2013-01-01 00:00:00

  • Cannabis and depression: an integrative data analysis of four Australasian cohorts.

    abstract：BACKGROUND:This study presents an integrative data analysis of the association between frequency of cannabis use and severity of depressive symptoms using data from four Australasian cohort studies. The integrated data comprised observations on over 6900 individuals studied on up to seven occasions between adolescence ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2012.06.002

    authors： Horwood LJ,Fergusson DM,Coffey C,Patton GC,Tait R,Smart D,Letcher P,Silins E,Hutchinson DM

    更新日期：2012-12-01 00:00:00

  • Alcohol high risk drinking, abuse and dependence among tobacco smoking medical care patients and the general population.

    abstract：BACKGROUND:Little is known about the synergies of smoking and alcohol consumption in medical care patients. The objective, therefore, is to estimate the coincidence of hazardous and harmful alcohol consumption as well as alcohol abuse and dependence with tobacco smoking in a general hospital and general practices. MET...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/s0376-8716(02)00315-0

    authors： John U,Hill A,Rumpf HJ,Hapke U,Meyer C

    更新日期：2003-03-01 00:00:00

  • Social relationships and intravenous drug use among methadone maintenance patients.

    abstract：:This study examined the extent to which social relationships were associated with continued injection drug use and needle sharing among 252 methadone maintenance patients. Logistic regression analyses indicated that drug use was highest among persons who had a substance using live-in partner and among those with more ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/s0376-8716(00)00230-1

    authors： Gogineni A,Stein MD,Friedmann PD

    更新日期：2001-09-01 00:00:00

  • Gray-matter volume in methamphetamine dependence: cigarette smoking and changes with abstinence from methamphetamine.

    abstract：BACKGROUND:Group differences in brain structure between methamphetamine-dependent and healthy research participants have been reported, but findings in the literature present discrepancies. Although most methamphetamine-abusing individuals also smoke cigarettes, the effects of smoking on brain structure have not been d...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2012.02.017

    authors： Morales AM,Lee B,Hellemann G,O'Neill J,London ED

    更新日期：2012-10-01 00:00:00

  • Correlates of HIV infection among female sex workers in Vietnam: injection drug use remains a key risk factor.

    abstract：OBJECTIVE:Women who sell sex and use drugs have dual risks for HIV infection. Despite increasing reports of drug use among female sex workers (FSW) in Vietnam, FSW HIV interventions remain focused mainly on sexual risk reduction. We assessed the impact of drug use and inconsistent condom use on HIV infection among FSW ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2015.02.006

    authors： Le LV,Nguyen TA,Tran HV,Gupta N,Duong TC,Tran HT,Nadol P,Sabin K,Maher L,Kaldor JM

    更新日期：2015-05-01 00:00:00

  • Reduced cortical gray matter volume in male adolescents with substance and conduct problems.

    abstract：UNLABELLED:Boys with serious conduct and substance problems (Antisocial Substance Dependence (ASD)) repeatedly make impulsive and risky decisions in spite of possible negative consequences. Because prefrontal cortex (PFC) is involved in planning behavior in accord with prior rewards and punishments, structural abnormal...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2011.04.006

    authors： Dalwani M,Sakai JT,Mikulich-Gilbertson SK,Tanabe J,Raymond K,McWilliams SK,Thompson LL,Banich MT,Crowley TJ

    更新日期：2011-11-01 00:00:00

  • Tobacco advertising, environmental smoking bans, and smoking in Chinese urban areas.

    abstract：OBJECTIVES:To evaluate whether cigarette smoking in Chinese urban areas was respectively associated with exposure to tobacco advertising and smoking bans in households, workplaces, and public places. METHODS:Participants were 4735 urban residents aged 15 years and older, who were identified through multi-stage quota-s...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2011.12.021

    authors： Yang T,Rockett IR,Li M,Xu X,Gu Y

    更新日期：2012-07-01 00:00:00

  • Effect of variation in BDNF Val(66)Met polymorphism, smoking, and nicotine dependence on symptom severity of depressive and anxiety disorders.

    abstract：BACKGROUND:Smoking, especially nicotine dependence is associated with more severe symptoms of depression and anxiety disorders. However, the mechanisms underlying this association are unclear. We investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive an...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2014.12.032

    authors： Jamal M,Van der Does W,Penninx BW

    更新日期：2015-03-01 00:00:00

  • Differences in heroin addicts seeking inpatient detoxification, ambulatory detoxification, or methadone maintenance.

    abstract：:Fifteen psychosocial characteristics of 300 male and 90 female heroin addicts admitted for inpatient detoxification, ambulatory detoxification, and methadone maintenance within the same multiphasic drug-abuse program were compared to determine whether or not their characteristics differentiated those seeking each type...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(79)90072-3

    authors： Steer RA

    更新日期：1979-09-01 00:00:00

  • Reductions in physical pain predict lower risk of relapse following alcohol treatment.

    abstract：OBJECTIVE:Physical pain is considered a potential predictor of relapse in alcohol-dependent individuals after treatment. The aim of this study was to evaluate whether reductions in pain level during the follow-up period after treatment were associated with lower relapse risk. METHOD:A sample of 366 participants was re...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2015.11.020

    authors： Jakubczyk A,Ilgen MA,Kopera M,Krasowska A,Klimkiewicz A,Bohnert A,Blow FC,Brower KJ,Wojnar M

    更新日期：2016-01-01 00:00:00

  • Substance use after participation in laboratory studies involving smoked cocaine self-administration.

    abstract：OBJECTIVE:Laboratory studies in which drugs of abuse are self- or experimenter-administered to non-treatment-seeking research volunteers provide valuable data about new pharmacotherapies for substance use disorders, as well as behavioral and performance data for understanding the neurobiology of drug abuse. This paper ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2011.07.015

    authors： Kalapatapu RK,Bedi G,Haney M,Evans SM,Rubin E,Foltin RW

    更新日期：2012-01-01 00:00:00

  • Blood levels do not predict behavioral or physiological effects of Δ⁹-tetrahydrocannabinol in rhesus monkeys with different patterns of exposure.

    abstract：BACKGROUND:Recent changes in the legality of cannabis have prompted evaluation of whether blood levels of Δ(9)-tetrahydrocannabinol (THC) or its metabolites could be used to substantiate impairment, particularly related to behavioral tasks such as driving. However, because marked tolerance develops to behavioral effect...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2014.02.696

    authors： Ginsburg BC,Hruba L,Zaki A,Javors MA,McMahon LR

    更新日期：2014-06-01 00:00:00

  • Brain macrostructural and microstructural abnormalities in cocaine dependence.

    abstract：RATIONALE:Two previous studies have utilized diffusion tensor imaging (DTI) to examine microstructural integrity in cocaine abuse and found evidence of brain abnormalities in white matter. OBJECTIVE:Using anatomical magnetic resonance imaging (MRI), DTI, and clinical evaluation, the macrostructural and microstructural...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2007.07.019

    authors： Lim KO,Wozniak JR,Mueller BA,Franc DT,Specker SM,Rodriguez CP,Silverman AB,Rotrosen JP

    更新日期：2008-01-01 00:00:00

  • Recreational marijuana legalization and prescription opioids received by Medicaid enrollees.

    abstract：OBJECTIVES:Medical marijuana use may substitute prescription opioid use, whereas nonmedical marijuana use may be a risk factor of prescription opioid misuse. This study examined the associations between recreational marijuana legalization and prescription opioids received by Medicaid enrollees. METHODS:State-level qua...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2018.09.016

    authors： Shi Y,Liang D,Bao Y,An R,Wallace MS,Grant I

    更新日期：2019-01-01 00:00:00

  • Exposure to the Lebanon War of 2006 and effects on alcohol use disorders: the moderating role of childhood maltreatment.

    abstract：BACKGROUND:Civilian populations now comprise the majority of casualties in modern warfare, but effects of war exposure on alcohol disorders in the general population are largely unexplored. Accumulating literature indicates that adverse experiences early in life sensitize individuals to increased alcohol problems after...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2013.10.014

    authors： Keyes KM,Shmulewitz D,Greenstein E,McLaughlin K,Wall M,Aharonovich E,Weizman A,Frisch A,Spivak B,Grant BF,Hasin D

    更新日期：2014-01-01 00:00:00

  • The ClockΔ19 mutation in mice fails to alter the primary and secondary reinforcing properties of nicotine.

    abstract：BACKGROUND:Clock genes have been demonstrated to play a role in behavioral responses to a variety of drugs of abuse, including cocaine, amphetamine, morphine, and ethanol. However, no studies to date have examined the role of Clock genes on nicotine-mediated behaviors. We examined the involvement of Clock, one of sever...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2013.08.024

    authors： Bernardi RE,Spanagel R

    更新日期：2013-12-01 00:00:00

  • Attitudes of North Carolina law enforcement officers toward syringe decriminalization.

    abstract：BACKGROUND:North Carolina, like much of the U.S. South, is disproportionately affected by HIV and hepatitis. This persistently high disease burden may be driven in part by laws that criminalize the possession and distribution of syringes for illicit drug use. Legal change to decriminalize syringes may reduce infection ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2014.08.007

    authors： Davis CS,Johnston J,de Saxe Zerden L,Clark K,Castillo T,Childs R

    更新日期：2014-11-01 00:00:00

  • Male alcohol use and unprotected sex with non-regular partners: evidence from wine shops in Chennai, India.

    abstract：BACKGROUND:In India, heterosexual transmission accounts for approximately 80% of the spread of HIV, the virus that causes AIDS. Male alcohol use and its putative association with sexual risk are explored to inform HIV prevention interventions. METHODS:A survey of 1196 male patrons of wine shops or bars was conducted f...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2007.11.016

    authors： Sivaram S,Srikrishnan AK,Latkin C,Iriondo-Perez J,Go VF,Solomon S,Celentano DD

    更新日期：2008-04-01 00:00:00