Beckwitt-Wiedemann's syndrome with medullary sponge kidneys, agonadism and persistent testosterone production.


:A patient with Beckwitt-Wiedemann's syndrome is described in which associated malformations were hemihypertrophy of the body, medullary sponge kidneys and absence of testes and internal ducts. On the other hand, we demonstrated biochemically the existence of testosterone secretion, with active response to a 3-day HCG stimulation as well as prepuberty levels LH and FSH. This demonstrated the existence of functioning Leydig's cells. The diagnosis of agonadism and anorchia could not be entirely true since they lead to an erroneous conclusion that there always are some disseminated Leydig's cells.


Eur Urol


European urology


Salgado AL,Macia AL,Freire A,Paramo P,Fernandez-Cruz A




Has Abstract


1977-01-01 00:00:00












  • Renal cysts. II. Chemical and dynamic study of cystic fluid.

    abstract::The chemical analysis of the fluid obtained by puncturing 100 simple renal cysts in adults show that the composition of cystic fluid resembles that of interstitial fluid. The chemical balance between cystic fluid and the interstitial space seems to occur passively. Antibiotics which were given orally (amoxycilline, mi...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Steg A

    更新日期:1976-01-01 00:00:00

  • Use of computerized cell image analysis to characterize cell nucleus populations from normal and neoplastic renal tissues.

    abstract::We studied 55 renal tissue samples from 16 patients corresponding to normal (19 samples, group 1), low-grade (18 samples, group 2), and high-grade (18 samples, group 3) tumoral tissues. For this purpose, we used digital cell image analysis (the SAMBA 200 processor) to describe the morphonuclear patterns of Feulgen-sta...

    journal_title:European urology

    pub_type: 杂志文章


    authors: vanden Houte K,Kiss R,de Prez C,Verhest A,Pasteels JL,van Velthoven R

    更新日期:1991-01-01 00:00:00

  • Acupuncture versus paroxetine for the treatment of premature ejaculation: a randomized, placebo-controlled clinical trial.

    abstract:BACKGROUND:Acupuncture therapy has been used by many researchers in both male and female sexual dysfunction studies. OBJECTIVE:To determine whether acupuncture is effective as a premature ejaculation (PE) treatment compared with paroxetine and placebo. DESIGN, SETTING, AND PARTICIPANTS:The study was conducted with me...

    journal_title:European urology

    pub_type: 杂志文章,随机对照试验


    authors: Sunay D,Sunay M,Aydoğmuş Y,Bağbancı S,Arslan H,Karabulut A,Emir L

    更新日期:2011-05-01 00:00:00

  • Correlation of embryonic development and adult neoplastic changes of human prostate.

    abstract::We have studied embryonic and fetal differentiation of the human prostate in relation to androgen-producing Leydig cell differentiation. We have studied the differentiation of human prostatic glands and the synthesis of acid phosphatase in vivo and in vitro. These studies have shown that the mesenchyme at the level of...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Kellokumpu-Lehtinen P

    更新日期:1989-01-01 00:00:00

  • Bard BTA test compared with voided urine cytology in the diagnosis of recurrent bladder cancer.

    abstract:OBJECTIVE:To compare the Bard BTA (bladder tumour antigen) test with voided urine cytology (VUC) in the diagnosis of recurrent bladder cancer (BC). METHODS:Urine specimens for the BTA test and VUC were collected on the same day as before cystoscopy from patients undergoing routine surveillance cystoscopy for recurrent...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Leyh H,Mazeman E

    更新日期:1997-01-01 00:00:00

  • Osteocalcin gene HindIII C/T polymorphism is a biomarker for prostate cancer and responsiveness to hormone therapy.

    abstract:OBJECTIVES:Osteocalcin is a vitamin-K dependent protein which is related to the metabolism of bone and calcium. The formation or progression of prostate cancer is presumed to be associated with the osteocalcin gene. The most frequently seen polymorphism is HindIII which is located at the promoter region. HindIII is the...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Wu HC,Lin CC,Chen WC,Chen HY,Tsai FJ

    更新日期:2003-02-01 00:00:00

  • Peyronie's disease: prevalence and association with cigarette smoking. A multicenter population-based study in men aged 50-69 years.

    abstract:OBJECTIVES:We present a multicenter, population-based epidemiological survey aimed at assessing the prevalence of Peyronie's disease (PD) and its potential risk factors in the general population. METHODS:In each of the ten centers throughout Italy, a uroandrologist contacted all the men in the age range 50-69 years re...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究


    authors: La Pera G,Pescatori ES,Calabrese M,Boffini A,Colombo F,Andriani E,Natali A,Vaggi L,Catuogno C,Giustini M,Taggi F,SIMONA Study Group.

    更新日期:2001-11-01 00:00:00

  • Methotrexate, vinblastine, adriamycin and cisplatin versus methotrexate and cisplatin in advanced urothelial cancer. A randomized study.

    abstract::From September 1984 to December 1988, 28 consecutive patients with metastatic urothelial cancer entered a randomized study to compare 4 courses of modified methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) to 4 courses of methotrexate followed by folinic acid rescue and cisplatin (MP). Non-responders or rela...

    journal_title:European urology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Pizzocaro G,Milani A,Piva L,Faustini M,Spino E

    更新日期:1991-01-01 00:00:00

  • Transitional cell carcinoma arising from bladder left behind.

    abstract::A case of transitional cell carcinoma arising from a bladder which was left behind for more than 24 years without pyocystis syndrome is described. A search in the literature revealed 10 cases of defunctionalized bladder that developed tumors over a rather short latent period ranging from 3 months to 7 years, and mostl...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Asano S,Matsuda M,Takemoto M,Osafune M,Sagawa S

    更新日期:1979-01-01 00:00:00

  • Contemporary management of small renal masses.

    abstract:CONTEXT:An increasing number of small renal masses (SRMs) with heterogeneous histology and clinical behaviour are being detected with modern radiologic imaging. Although surgical removal is the standard of care for small renal tumours, alternative minimally invasive and conservative treatment options are possible in se...

    journal_title:European urology

    pub_type: 杂志文章,评审


    authors: Volpe A,Cadeddu JA,Cestari A,Gill IS,Jewett MA,Joniau S,Kirkali Z,Marberger M,Patard JJ,Staehler M,Uzzo RG

    更新日期:2011-09-01 00:00:00

  • Intratesticular effects of cisplatin-based chemotherapy.

    abstract::The question is addressed whether cisplatin-based chemotherapy for germ cell cancer has the same efficacy in intratesticular and in extragonadal sites. For this purpose, 7 patients with germ cell cancer, aged 16-35 years were analysed. Four of the patients had palpable testicular tumors, 3 had occult testicular tumors...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Dieckmann KP,Loy V

    更新日期:1995-01-01 00:00:00

  • Shock wave lithotripsy treatment of radiolucent ureteric calculi with the help of contrast medium.

    abstract:OBJECTIVE:Extracorporeal shock wave lithotripsy (SWL) treatment of radiolucent ureteric calculi (UC) is hampered by the reduced visibility of the stone. Intravenous contrast medium (IV-CM) administration may overcome this problem by indirectly depicting the localisation of the stone. However, IV-CM administration bears...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Buchholz NP,van Rossum M

    更新日期:2001-02-01 00:00:00

  • Radical pelvic surgery and radiation therapy in the management of localized carcinoma of the prostate.

    abstract::A total of 181 prostatic cancer patients under radiation monotherapy were tested for the therapeutic effect of pelvic lymphadenectomy (PLA). Sixty-seven belonging to the pN0 category formed a highly selective group and presented a 89% rate of 7-year survival. Localized radiation therapy with pelvic irradiation (81 pat...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Schubert J,Kelly LU,Wehnert J,Moravek P

    更新日期:1988-01-01 00:00:00

  • Prostate specific antigen doubling time as auxiliary end point in hormone refractory prostatic carcinoma.

    abstract:OBJECTIVE:In hormone refractory prostatic carcinoma (HRPCa), the majority of patients have bone metastases only, which are by definition non-measurable. This makes objective evaluation of chemotherapeutic agents difficult. Prostate specific antigen (PSA) as a dynamic model was analyzed as potential auxiliary end point ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Schmid HP,Morant R,Bernhard J,Maibach R,Swiss Group for Clinical Cancer Research (SAKK).

    更新日期:2003-01-01 00:00:00

  • Cumulative prostate cancer risk assessment with the aid of the free-to-total prostate specific antigen ratio.

    abstract:OBJECTIVE:To evaluate the cumulative risk of having a prostate cancer diagnosis in a repeated screening situation in relation to the free-to-total prostate specific antigen ratio (F/T-PSA). PATIENTS AND METHODS:The present study includes 1385 men (aged 50-70 years) who underwent prostate biopsy for the first time in t...

    journal_title:European urology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Aus G,Becker C,Franzén S,Lilja H,Lodding P,Hugosson J

    更新日期:2004-02-01 00:00:00

  • Urethral-sparing Robot-assisted Simple Prostatectomy: An Innovative Technique to Preserve Ejaculatory Function Overcoming the Limitation of the Standard Millin Approach.

    abstract:BACKGROUND:Despite recent technical innovations in the treatment of benign prostatic hyperplasia (BPH), retrograde ejaculation is still one of the most frequent adverse effects, with a major impact on patients' quality of life. OBJECTIVE:To evaluate the efficacy of our technique of urethral-sparing robotic-assisted si...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Porpiglia F,Checcucci E,Amparore D,Niculescu G,Volpi G,Piramide F,De Cillis S,Manfredi M,Autorino R,Fiori C

    更新日期:2020-10-05 00:00:00

  • Tumor recurrence in prostatic urethra following simultaneous resection of bladder tumor and prostate.

    abstract::A comparative retrospective study was performed on 100 patients who had undergone transurethral resection of a superficial bladder tumor (Ta-Tl) with no associated carcinoma in situ (group 1) and 100 patients who had undergone simultaneous transurethral resection of a superficial bladder tumor (Ta-Tl), with no associa...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Vicente J,Chéchile G,Pons R,Méndez G

    更新日期:1988-01-01 00:00:00

  • Drug adherence and clinical outcomes for patients under pharmacological therapy for lower urinary tract symptoms related to benign prostatic hyperplasia: population-based cohort study.

    abstract:BACKGROUND:Little is known about drug adherence in men treated for lower urinary tract symptoms (LUTS). Benign prostatic hyperplasia (BPH) is one of the causes of LUTS. OBJECTIVE:To examine adherence to pharmacological therapy and its clinical value in men with LUTS. DESIGN, SETTING, AND PARTICIPANTS:Population-based...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Cindolo L,Pirozzi L,Fanizza C,Romero M,Tubaro A,Autorino R,De Nunzio C,Schips L

    更新日期:2015-09-01 00:00:00

  • Phosphodiesterase type 5 inhibitors: the day after.

    abstract:OBJECTIVE:Review the literature on phosphodiesterase type 5 inhibitors (PDE5-Is), addressing critical issues in their current and future use, assessing unanswered questions, and identifying research needs. METHODS:A MEDLINE search was conducted on PDE5-Is, with emphasis on clinical trials and experience, for interpret...

    journal_title:European urology

    pub_type: 杂志文章,评审


    authors: Hatzimouratidis K,Hatzichristou D

    更新日期:2007-01-01 00:00:00

  • Describing the Grade of Prostate Cancer: Consistent Use of Contemporary Terminology Is Now Required.

    abstract::Editors of the major urological literature advocate the use of the recent Gleason Grade groupings when reporting analyses of prostate cancer. ...

    journal_title:European urology

    pub_type: 社论


    authors: Zietman A,Smith J,Klein E,Droller M,Dasgupta P,Catto J

    更新日期:2016-07-01 00:00:00

  • Sexual functioning of adult patients born with meningomyelocele. A pilot study.

    abstract:OBJECTIVES:This pilot study was started to get an impression of the sexual activity and sexual difficulties of adult patients born with meningomyelocele in control at Utrecht University Hospital, and to find out whether these problems deserve more attention from the Spina Bifida Team. METHODS:Seventeen patients (9 men...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Vroege JA,Zeijlemaker BY,Scheers MM

    更新日期:1998-01-01 00:00:00

  • Total androgen blockade: the United States experience.

    abstract::Maximal androgen blockade may improve the effectiveness of treatment of prostate cancer. To test this hypothesis we conducted a randomized, double-blind trial in patients with disseminated and previously untreated prostate cancer (stage D2). All patients (n = 603) received leuprolide, 1 mg/day s.c. in combination with...

    journal_title:European urology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Benson RC

    更新日期:1993-01-01 00:00:00

  • Robot-assisted Cavectomy Versus Thrombectomy for Level II Inferior Vena Cava Thrombus: Decision-making Scheme and Multi-institutional Analysis.

    abstract:BACKGROUND:Robot-assisted thrombectomy (RAT) for inferior vena cava (IVC) thrombus (RAT-IVCT) is being increasingly reported. However, the techniques and indications for robot-assisted cavectomy (RAC) for IVC thrombus are not well described. OBJECTIVE:To develop a decision-making program and analyze multi-institutiona...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Shi T,Huang Q,Liu K,Du S,Fan Y,Yang L,Peng C,Shen D,Wang Z,Gao Y,Gu L,Niu S,Ai Q,Li H,Liu F,Li Q,Wang H,Guo A,Fu B,Yang X,Zhang X,Wang D,Wang D,Guo H,Li H,Olivero A,Fam XI,Ma X,Wang B,Zhang X

    更新日期:2020-10-01 00:00:00

  • Myelolipoma of the adrenal gland.

    abstract::Adrenal myelolipoma is a rare benign tumor that is usually asymptomatic. This case is believed to be the 13th surgically removed, attesting to the rarity of this tumor. ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Hanafy HM

    更新日期:1981-01-01 00:00:00

  • Spontaneous regression of pulmonary metastases and long-term survival of a patient with metastatic renal cell carcinoma, after immunostimulation with bacillus Calmette-Guérin and extirpation of brain and contralateral lung metastases.

    abstract::A 52-year-old patient underwent left radical nephrectomy for renal cell carcinoma and received adjuvant chemotherapy postoperatively with adriamycin and 5-fluoruracil. Twenty months afterwards he developed cerebral and multiple bilateral pulmonary metastases. The cerebral metastasis was excised and nonspecific immunos...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Martínez-Piñeiro L,de la Peña J,Picazo ML,Jiménez León J,Beneitez M,Martínez-Piñeiro JA

    更新日期:1988-01-01 00:00:00

  • Improved Reporting of Randomized Controlled Trials in the Urologic Literature.

    abstract:BACKGROUND:Well-designed randomized controlled trials (RCTs) have the potential to provide high-quality evidence to inform questions of therapy and prevention, but this potential is contingent on the use of appropriate methods and transparent reporting. OBJECTIVE:To systematically assess the quality of urology RCT rep...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Narayan VM,Cone EB,Smith D,Scales CD Jr,Dahm P

    更新日期:2016-12-01 00:00:00

  • Developing and validating the International Consultation on Incontinence Questionnaire bladder diary.

    abstract:BACKGROUND:Despite the common use of urinary diaries to assess lower urinary tract symptoms (LUTS), a standardised validated diary does not exist. OBJECTIVE:To develop a validated urinary diary, using the psychometric validation protocol used in previous International Consultation on Incontinence Questionnaire (ICIQ) ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Bright E,Cotterill N,Drake M,Abrams P

    更新日期:2014-08-01 00:00:00

  • Interstitial cystitis as an autoimmune disease. A review.

    abstract::The autoimmune features of interstitial cystitis are reviewed. Despite some controversy, interstitial cystitis should be grouped to the connective tissue diseases but as a separate entity. ...

    journal_title:European urology

    pub_type: 杂志文章,评审


    authors: Oravisto KJ

    更新日期:1980-01-01 00:00:00

  • Significant antitumor effect of intratumoral ethanol injection on renal cell carcinoma.

    abstract:OBJECTIVE:The effects of intratumoral ethanol injection on renal cell carcinoma (RCC) heterotransplanted in nude rats were evaluated. MATERIALS AND METHODS:The OUR95AF human RCC cell line was inoculated subcutaneously into the backs of nude rats. Four weeks after transplantation, the size of tumors became 1.5-2.0 cm i...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Naitoh Y,Kawauchi A,Mizutani Y,Ukimura O,Fujito A,Nakao M,Kojima Y,Nonomura N,Okuyama A,Miki T

    更新日期:2003-10-01 00:00:00

  • Perioperative blood transfusion does not affect survival after operation for renal cell cancer.

    abstract::We retrospectively studied the effect of perioperative blood transfusion in 208 transfused and 50 nontransfused patients operated on during a 12-year period for renal cell cancer. The 5-year renal cell cancer specific survival rate was 0.46 in the transfused patients versus 0.62 in the nontransfused patients. However,...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Jakobsen EB,Eickhoff JH,Andersen JP,Ottesen M

    更新日期:1994-01-01 00:00:00