Beckwitt-Wiedemann's syndrome with medullary sponge kidneys, agonadism and persistent testosterone production.


:A patient with Beckwitt-Wiedemann's syndrome is described in which associated malformations were hemihypertrophy of the body, medullary sponge kidneys and absence of testes and internal ducts. On the other hand, we demonstrated biochemically the existence of testosterone secretion, with active response to a 3-day HCG stimulation as well as prepuberty levels LH and FSH. This demonstrated the existence of functioning Leydig's cells. The diagnosis of agonadism and anorchia could not be entirely true since they lead to an erroneous conclusion that there always are some disseminated Leydig's cells.


Eur Urol


European urology


Salgado AL,Macia AL,Freire A,Paramo P,Fernandez-Cruz A




Has Abstract


1977-01-01 00:00:00












  • Survival and Functional Stability in Chronic Kidney Disease Due to Surgical Removal of Nephrons: Importance of the New Baseline Glomerular Filtration Rate.

    abstract:BACKGROUND:Chronic kidney disease (CKD) can be associated with a higher risk of progression to end-stage renal disease and mortality, but the etiology of nephron loss may modify this. Previous studies suggested that CKD primarily due to surgical removal of nephrons (CKD-S) may be more stable and associated with better ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Lane BR,Demirjian S,Derweesh IH,Takagi T,Zhang Z,Velet L,Ercole CE,Fergany AF,Campbell SC

    更新日期:2015-12-01 00:00:00

  • Prognostic value of Ki-67 expression in renal cell carcinomas.

    abstract:OBJECTIVE:The aim of the study was to determine the prognostic power of Ki-67 immunostaining in renal cell carcinomas (RCC). METHODS:Clinical follow-up data were reviewed in 111 RCC and the results of Ki-67 immunolabelling were correlated to standard prognostic factors and survival data of the patients. RESULTS:Ki-67...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Aaltomaa S,Lipponen P,Ala-Opas M,Eskelinen M,Syrjänen K

    更新日期:1997-01-01 00:00:00

  • Trastuzumab (Herceptin) in metastatic transitional cell carcinoma of the urinary tract: report on six patients.

    abstract:OBJECTIVE:To report our preliminary experience with trastuzumab (Herceptin) in the management of metastatic transitional cell carcinoma of the urinary tract. PATIENTS AND METHODS:From november 2001 to august 2002, six patients received trastuzumab for metastatic transitional cell carcinoma of the bladder (n=5) or rena...

    journal_title:European urology

    pub_type: 临床试验,杂志文章


    authors: Peyromaure M,Scotté F,Amsellem-Ouazana D,Vieillefond A,Oudard S,Beuzeboc P

    更新日期:2005-11-01 00:00:00

  • Renal lesions in Von Hippel-Lindau disease: the benign, the malignant, the unknown.

    abstract:OBJECTIVES:To describe the features and treatment of renal lesions in von Hippel-Lindau disease (VHL) from a series of patients, to highlight important issues in the management of these lesions. MATERIALS AND METHODS:We performed a retrospective study in 7 patients with VHL who underwent surgery for renal lesions betw...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Salomé F,Colombeau P,Fermeaux V,Cazaux P,Dumas JP,Pfeifer P,Moreau JJ,Richard S,Labrousse F

    更新日期:1998-01-01 00:00:00

  • Tumor collagenase-stimulating factor and tumor autocrine motility factor as tumor markers in bladder cancer--an update.

    abstract::We have studied the role of combined measurements of tumor collagenase-stimulating factor (TCSF) and tumor autocrine motility factor (TAMF) in 83 first morning voids and 24-hour specimens in patients with bladder and renal cancer and control subjects. TCSF and TAMF were measured by immunoabsorption assay and motility ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Javadpour N,Guirguis R

    更新日期:1992-01-01 00:00:00

  • A systematic review of the literature on the prevalence of sexual impairment in women with urinary incontinence and the prevalence of urinary leakage during sexual activity.

    abstract:OBJECTIVE:To provide a synthesis of the literature concerning the impact of urinary incontinence on sexual lives of women and the prevalence of urinary incontinence during sexual activity. METHODS:Medline and PsycInfo were searched for all primary epidemiological articles reporting the prevalence of sexual incontinenc...

    journal_title:European urology

    pub_type: 杂志文章,评审


    authors: Shaw C

    更新日期:2002-11-01 00:00:00

  • Inhibitors of stone formation in hypercalciuric children with and without stone disease.

    abstract::The extretion of two inhibitors of urinary stone formation (citrate, magnesium) was evaluated in 71 hypercalciuric children and 50 controls. Patients were classified into two groups: 42 nonstone former (NSF), 22 boys and 20 girls, 3-14 years old, and 29 stone formers (SF), 18 boys and 11 girls, 2.5-18 years old. Our s...

    journal_title:European urology

    pub_type: 杂志文章


    authors: al-Qadreh A,Athanasopoulou H,Voskaki I

    更新日期:1992-01-01 00:00:00

  • When to perform bone scan in patients with newly diagnosed prostate cancer: external validation of the currently available guidelines and proposal of a novel risk stratification tool.

    abstract:BACKGROUND:Several guidelines have indicated that in patients with well-differentiated or moderately well-differentiated prostate cancer (PCa), a staging bone scan may be omitted. However, the guidelines recommendations have not yet been externally validated. OBJECTIVE:The aim of the study was to externally validate t...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Briganti A,Passoni N,Ferrari M,Capitanio U,Suardi N,Gallina A,Da Pozzo LF,Picchio M,Di Girolamo V,Salonia A,Gianolli L,Messa C,Rigatti P,Montorsi F

    更新日期:2010-04-01 00:00:00

  • Intratesticular effects of cisplatin-based chemotherapy.

    abstract::The question is addressed whether cisplatin-based chemotherapy for germ cell cancer has the same efficacy in intratesticular and in extragonadal sites. For this purpose, 7 patients with germ cell cancer, aged 16-35 years were analysed. Four of the patients had palpable testicular tumors, 3 had occult testicular tumors...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Dieckmann KP,Loy V

    更新日期:1995-01-01 00:00:00

  • Human papilloma virus DNA and p53 mutation analysis on bladder washes in relation to clinical outcome of bladder cancer.

    abstract:OBJECTIVES:High-risk human papilloma virus (HPV) types stimulate degradation and deactivation of protein associated with the p53 tumour suppressor gene via the ubiquitin-dependent pathway. For a long time, changes of the p53 tumour suppressor gene have been correlated with poor clinical outcome in patients with superfi...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Moonen PM,Bakkers JM,Kiemeney LA,Schalken JA,Melchers WJ,Witjes JA

    更新日期:2007-08-01 00:00:00

  • Prevalence of contralateral testicular intraepithelial neoplasia (carcinoma in situ) in patients with testicular germ cell tumour. Results of the German multicentre study.

    abstract::Contralateral biopsies taken from 1,188 patients with testicular germ-cell tumour were examined immunohistologically by staining for placental alkaline phosphatase. Testicular intraepithelial neoplasia (TIN; carcinoma in situ) was detected in 53 patients (4.5%; 95% confidence interval 3.3-5.7%). Testicular atrophy was...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究


    authors: Loy V,Dieckmann KP

    更新日期:1993-01-01 00:00:00

  • Spontaneous regression of pulmonary metastases and long-term survival of a patient with metastatic renal cell carcinoma, after immunostimulation with bacillus Calmette-Guérin and extirpation of brain and contralateral lung metastases.

    abstract::A 52-year-old patient underwent left radical nephrectomy for renal cell carcinoma and received adjuvant chemotherapy postoperatively with adriamycin and 5-fluoruracil. Twenty months afterwards he developed cerebral and multiple bilateral pulmonary metastases. The cerebral metastasis was excised and nonspecific immunos...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Martínez-Piñeiro L,de la Peña J,Picazo ML,Jiménez León J,Beneitez M,Martínez-Piñeiro JA

    更新日期:1988-01-01 00:00:00

  • Recoverability of erectile function in post-radical cystectomy patients: subjective and objective evaluations.

    abstract:BACKGROUND:Literature regarding both subjective and objective evaluations of erectile function following radical cystectomy is deficient. OBJECTIVE:To study the recoverability of erectile function in post-radical cystectomy patients on subjective and objective bases. DESIGN, SETTING, AND PARTICIPANTS:Between March 20...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Hekal IA,El-Bahnasawy MS,Mosbah A,El-Assmy A,Shaaban A

    更新日期:2009-02-01 00:00:00

  • Upper tract tumours in patients with vesico-ureteral reflux and recurrent bladder tumours.

    abstract::27 patients with recurrent low-grade, low-stage transitional cell carcinoma (TCC) of the bladder and uni- or bilateral vesico-ureteral reflux were followed for up to 18 years in order to study a possible higher incidence of TCC of the upper tract. None of the patients developed tumours of the upper collecting system d...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Mukamel E,Nissenkorn I,Glanz I,Vilcovsky E,Servadio C

    更新日期:1985-01-01 00:00:00

  • Identification of androgen receptors in the motoneurons of the external urethral sphincter in the spinal cord of female rats.

    abstract:OBJECTIVES:In women, aging is associated with profound hormonal changes. Menopause has been implicated in the etiology of urinary tract complaints including incontinence, urgency and recurrent urinary tract infections. However, the use of hormone replacement therapy for these conditions has given conflicting and disapp...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Blanchet P,Yaici el-D,Cayzergues L,Giuliano F,Jardin A,Benoit G,Droupy S

    更新日期:2005-01-01 00:00:00

  • A new case of pyelic fusion.

    abstract::The quite uncommon case of a girl with two kidneys drained by one single pelvis and one ureter is reported and a review of the literature is presented. ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Bruezière J,Frétin J

    更新日期:1980-01-01 00:00:00

  • Medical therapy to facilitate the passage of stones: what is the evidence?

    abstract:CONTEXT:Medical expulsive therapy (MET) for urolithiasis has gained increasing attention in the last years. It has been suggested that the administration of alpha-adrenoreceptor antagonists (alpha-blockers) or calcium channel blockers augments stone expulsion rates and reduces colic events. OBJECTIVE:To evaluate the e...

    journal_title:European urology

    pub_type: 杂志文章,评审


    authors: Seitz C,Liatsikos E,Porpiglia F,Tiselius HG,Zwergel U

    更新日期:2009-09-01 00:00:00

  • Organ-sparing treatment for ureteral carcinoma?

    abstract:OBJECTIVE:Nephroureterectomy (NUE) with a bladder cuff is the standard therapy for ureteral cancer. Based on an analysis of the literature and a retrospective study, this concept is questioned. METHODS:Between 1980 and 1991, 40 patients with ureteral tumors underwent surgery at the Krankenhaus der Barmherzigen Brüder ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Leitenberger A,Beyer A,Altwein JE

    更新日期:1996-01-01 00:00:00

  • Robotic partial nephrectomy for complex renal tumors: surgical technique.

    abstract:OBJECTIVES:Laparoscopic partial nephrectomy requires advanced training to accomplish tumor resection and renal reconstruction while minimizing warm ischemia times. Complex renal tumors add an additional challenge to a minimally invasive approach to nephron-sparing surgery. We describe our technique, illustrated with vi...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Rogers CG,Singh A,Blatt AM,Linehan WM,Pinto PA

    更新日期:2008-03-01 00:00:00

  • Is Gleason Grade 5 Prostate Cancer Resistant to Conventional Androgen Deprivation Therapy?

    abstract::Synthesis of data from randomized trials suggests that long-term versus short-term androgen deprivation therapy may be most effective in men with Gleason grade 4 prostate cancer (PCa) and less or ineffective in men with Gleason grade 5 PCa. ...

    journal_title:European urology

    pub_type: 社论


    authors: D'Amico AV

    更新日期:2016-05-01 00:00:00

  • Ultrasonic diagnosis of the retroperitoneal space.

    abstract::A precondition for ultrasonic diagnosis of the retroperitoneum is an optimal preparation of the patient to eliminate flatulence in the intestines. If the large vessels of the retroperitoneum are well demarcated, the optimal examination conditions are present. Tumorous and cystic changes of 2 cm or more, can be visuali...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Schmoller H,Kunit G,Frick J

    更新日期:1979-01-01 00:00:00

  • Transurethral prostatectomy: a long-term follow-up study of 166 patients over 80 years of age.

    abstract:OBJECTIVES AND METHODS:In a retrospective analysis, the medical records of 166 patients over 80 years of age (80-99 years, mean age 82 years) who underwent transurethral prostatectomy (TURP) for clinically benign prostatic hyperplasia (BPH) were reviewed in order to evaluate the morbidity and mortality rates in this sp...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Matani Y,Mottrie AM,Stöckle M,Voges GE,Fichtner J,Hohenfellner R

    更新日期:1996-01-01 00:00:00

  • Patient self-reporting questionnaire on urological morbidity and bother after radical retropubic prostatectomy.

    abstract:OBJECTIVES:We assessed the incidence of morbidity and bother on quality-of-life (QL) after radical retropubic prostatectomy for prostate cancer. METHODS:At least 12 months after surgery, self-reporting questionnaires were completed and returned by 368 (77.8%) of 473 eligible patients. Surgery related morbidity was eva...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Augustin H,Pummer K,Daghofer F,Habermann H,Primus G,Hubmer G

    更新日期:2002-08-01 00:00:00

  • A Systematic Review and Framework for the Use of Hormone Therapy with Salvage Radiation Therapy for Recurrent Prostate Cancer.

    abstract:CONTEXT:Salvage radiotherapy (SRT) is a standard of care for men who recur postprostatectomy, and recent randomized trials have assessed the benefit and toxicity of adding hormone therapy (HT) to SRT with differing results. OBJECTIVE:To perform a systematic review of randomized phase III trials of the use of SRT ± HT ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Spratt DE,Dess RT,Zumsteg ZS,Lin DW,Tran PT,Morgan TM,Antonarakis ES,Nguyen PL,Ryan CJ,Sandler HM,Cooperberg MR,Posadas E,Feng FY

    更新日期:2018-02-01 00:00:00

  • Association of smoking with urgency in older people.

    abstract:OBJECTIVE:To evaluate the association of smoking with urgency in older people. METHODS:A population-based survey involving 1,059 people aged 60-89 years. A stratified sampling method was used and data were collected by interviews. The response rate was 82%. The indicators were urgency, former and current smoking, alco...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Nuotio M,Jylhä M,Koivisto AM,Tammela TL

    更新日期:2001-08-01 00:00:00

  • Late recurrence and progression after a long tumor-free period in primary Ta and T1 bladder cancer.

    abstract:OBJECTIVE:To determine the probability and risk factors of recurrence and progression (to T2 or worse) after a long tumor-free period in patients with superficial (stage Ta and T1) bladder cancer. PATIENTS AND METHODS:A consecutive series of 100 patients with superficial bladder cancer who remained tumor-free for long...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Fujii Y,Fukui I,Kihara K,Tsujii T,Kageyama Y,Oshima H

    更新日期:1999-10-01 00:00:00

  • Prospective Implementation of Enhanced Recovery After Surgery Protocols to Radical Cystectomy.

    abstract:BACKGROUND:Multimodal enhanced recovery after surgery (ERAS) regimens have improved outcomes from colorectal surgery. OBJECTIVE:We report the application of ERAS to patients undergoing radical cystectomy (RC). DESIGN, SETTING, AND PARTICIPANTS:Prospective collection of outcomes from consecutive patients undergoing RC...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Pang KH,Groves R,Venugopal S,Noon AP,Catto JWF

    更新日期:2018-03-01 00:00:00

  • Sigmoid kidney associated with renal adenocarcinoma.

    abstract::A rare case of adenocarcinoma in a sigmoid kidney is reported. The literature is reviewed and the operative technique described. Preoperative arteriogram and cavogram are an essential part of the evaluation and provide aid in the surgical approach. ...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Vandendris M,Schulman CC,Struyven J,Grégoir W

    更新日期:1975-01-01 00:00:00

  • Is ipsilateral testis mandatory for the occurrence of contralateral intratesticular biochemical changes indicative of hypoxia after unilateral spermatic cord torsion?

    abstract::Experimental unilateral spermatic cord torsion has been shown to induce both ipsilateral and contralateral intratesticular biochemical changes indicative of hypoxia. An experimental study was conducted to see whether the presence of the ipsilateral testicular tissue is necessary for the occurrence of the biochemical c...

    journal_title:European urology

    pub_type: 杂志文章


    authors: Akgür FM,Kilinç K,Aktuğ T

    更新日期:1995-01-01 00:00:00

  • Describing the Grade of Prostate Cancer: Consistent Use of Contemporary Terminology Is Now Required.

    abstract::Editors of the major urological literature advocate the use of the recent Gleason Grade groupings when reporting analyses of prostate cancer. ...

    journal_title:European urology

    pub_type: 社论


    authors: Zietman A,Smith J,Klein E,Droller M,Dasgupta P,Catto J

    更新日期:2016-07-01 00:00:00