Bipolar Androgen Therapy: A Paradoxical Approach for the Treatment of Castration-resistant Prostate Cancer.

abstract：:A case of urinary obstruction caused by vulvar fusion in an adult is reported. Anterograde micturition-urethrocystography revealed reflux of urine in the vagina and cavum uteri. Treatment consisted of sharp separation of the labia. Ointment dressing was applied to prevent reagglutination. After 1 year the patient has ...

journal_title：European urology

authors： Varenhorst E

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Standard management in the UK for high-risk stage 1 nonseminoma germ cell tumours of the testis (NSGCTT) is two cycles of adjuvant bleomycin, etoposide (360 mg/m2), and cisplatin (BE360P) chemotherapy, or surveillance. OBJECTIVE:To test whether one cycle of BE500P achieves similar recurrence rates to two cy...

journal_title：European urology

authors： Cullen M,Huddart R,Joffe J,Gardiner D,Maynard L,Hutton P,Mazhar D,Shamash J,Wheater M,White J,Goubar A,Porta N,Witts S,Lewis R,Hall E,111 Trial Management Group.

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the prognostic power of Ki-67 immunostaining in renal cell carcinomas (RCC). METHODS:Clinical follow-up data were reviewed in 111 RCC and the results of Ki-67 immunolabelling were correlated to standard prognostic factors and survival data of the patients. RESULTS:Ki-67...

journal_title：European urology

authors： Aaltomaa S,Lipponen P,Ala-Opas M,Eskelinen M,Syrjänen K

更新日期：1997-01-01 00:00:00

abstract：CONTEXT:Overexpression of immune checkpoint molecules affects tumor-specific T-cell immunity in the cancer microenvironment, and can reshape tumor progression and metastasis. Antibodies targeting checkpoints could restore antitumor immunity by blocking the inhibitory receptor-ligand interaction. OBJECTIVE:To analyze d...

journal_title：European urology

authors： Carosella ED,Ploussard G,LeMaoult J,Desgrandchamps F

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the effect of adjuvant chemotherapy in invasive bladder cancer. METHODS:: We conducted a systematic review and meta-analysis of updated individual patient data from all available randomised controlled trials comparing local treatment plus adjuvant chemotherapy versus the same local treatment alo...

journal_title：European urology

authors： Advanced Bladder Cancer (ABC) Meta-analysis Collaboration.

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:Congenital bladder diverticula (CBD) usually occur in areas where the muscle is inadequately formed, typically at the ureterovesical junction, or between bundles of hypertrophied muscle. CBD are mostly asymptomatic and the cases are found incidentally. Occasionally, some cases of CBD may produce urinary obstr...

journal_title：European urology

authors： Sarihan H,Abes M

更新日期：1998-01-01 00:00:00

abstract：:Ureteral injuries following blunt pelvic trauma are extremely rare. Experiences with two cases of lacerations of the lower ureter due to pelvic fractures are presented. In patients with acetabular fractures the likelihood of lower ureteral injuries should be suspected and excluded by an intravenous urogram. ...

journal_title：European urology

authors： Bick C,Oesterwitz H,Ziegler PF

更新日期：1984-01-01 00:00:00

abstract：CONTEXT:Biomarker-driven cancer therapy, also referred to as precision oncology, has received increasing attention for its promise of improving patient outcomes by defining subsets of patients more likely to respond to various therapies. OBJECTIVE:In this collaborative review article, we examine recent literature rega...

journal_title：European urology

authors： Barbieri CE,Chinnaiyan AM,Lerner SP,Swanton C,Rubin MA

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Tri-modality therapy (TMT) is a recognized treatment strategy for selected patients with muscle-invasive bladder cancer (MIBC). OBJECTIVE:Report long-term outcomes of patients with MIBC treated by TMT. DESIGN, SETTING, AND PARTICIPANTS:Four hundred and seventy-five patients with cT2-T4a MIBC were enrolled ...

journal_title：European urology

authors： Giacalone NJ,Shipley WU,Clayman RH,Niemierko A,Drumm M,Heney NM,Michaelson MD,Lee RJ,Saylor PJ,Wszolek MF,Feldman AS,Dahl DM,Zietman AL,Efstathiou JA

更新日期：2017-06-01 00:00:00

abstract：:An in vitro assay, which evaluates the effect of drugs on labelled DNA precursor incorporation into fresh specimens after 3 h of in vitro treatment, was used for a prospective study. Drugs were used as monochemotherapy or in different combinations according to their in vitro activities for salvage or palliation treatm...

journal_title：European urology

authors： Sanfilippo O,Silvestrini R,Salvioni R,Pizzocaro G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The availability of new agents (NAs) active in patients with metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel treatment (abiraterone acetate, cabazitaxel, and enzalutamide) has led to the possibility of using them sequentially to obtain a cumulative survival benefit. OBJEC...

journal_title：European urology

authors： Caffo O,De Giorgi U,Fratino L,Alesini D,Zagonel V,Facchini G,Gasparro D,Ortega C,Tucci M,Verderame F,Campadelli E,Lo Re G,Procopio G,Sabbatini R,Donini M,Morelli F,Sartori D,Zucali P,Carrozza F,D'Angelo A,Vicario

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To investigate the prostate cancer (PCa) prevalence and risk factors of men with prostate-specific antigen (PSA) level< or =4.0 ng/ml and an unsuspicious digital rectal examination (DRE) in a large biopsy referral cohort. MATERIALS AND METHODS:Between 1997 and 2005, 855 men underwent initial transrectal ultr...

journal_title：European urology

authors： Ahyai SA,Graefen M,Steuber T,Haese A,Schlomm T,Walz J,Köllermann J,Briganti A,Zacharias M,Friedrich MG,Karakiewicz PI,Montorsi F,Huland H,Chun FK

更新日期：2008-04-01 00:00:00

abstract：:The influence of intravesical ions, osmolality, pH value, and active transurothelial NaCl-transport inhibition (furosemide) on the rat bladder volume-pressure response was studied according to the concept of a permeable urothelium and according to direct effects of osmolality and K+ on in vitro muscle preparations. It...

journal_title：European urology

authors： Hohlbrugger G,Lentsch P

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Patients with urgency urinary incontinence (UUI) due to overactive bladder (OAB) refractory to oral antimuscarinics have limited therapeutic options. OnabotulinumtoxinA appears to be an effective new treatment. OBJECTIVE:Assess disease-specific quality-of-life outcomes and general health-related quality-of-...

journal_title：European urology

authors： Fowler CJ,Auerbach S,Ginsberg D,Hale D,Radziszewski P,Rechberger T,Patel VD,Zhou J,Thompson C,Kowalski JW

更新日期：2012-07-01 00:00:00

abstract：AIM:The uroflowmetry data of a selected number of patients who took part to the QUIBUS study (366 traces selected after quality control by a central panel of reviewer) were evaluated for their relationships with age, prostate volume, and IPSS and ICS-BPH scores. Waiting time, flow time, voided volume, maximum flow rate...

journal_title：European urology

authors： Porru D,Bartoletti R,Austoni E,Carrino M,Gianneo E,Melloni D

更新日期：2001-01-01 00:00:00

abstract：:Urinary incontinence (UI) is a debilitating and embarrassing condition that is prevalent among aging males and females. Little is known about UI in the home hospice setting. We sought to determine UI prevalence and risk factors in a cohort of 15432 home hospice patients over 4yr. Most of the study patients were female...

journal_title：European urology

authors： Chughtai B,Thomas D,Russell D,Bowles K,Prigerson H

更新日期：2019-02-01 00:00:00

abstract：:The use of carbon dioxide laser for 38 posthetomies or therapeutic circumcisions in the treatment of phimosis, paraphimosis, balanitis of Zoon or a genital infection by the human papillomaviurs permits clean and hemostatic incisions. The clean and dry wound produced by the carbon dioxide beam offers several advantages...

journal_title：European urology

authors： Aynaud O,Casanova JM,Tranbaloc P

更新日期：1995-01-01 00:00:00

abstract：CONTEXT:The use of neoadjuvant and adjuvant chemotherapy in the treatment of muscle-invasive bladder cancer is still controversial. OBJECTIVE:To determine the optimal use of chemotherapy in the neoadjuvant and adjuvant settings in patients with advanced urothelial cell carcinoma. Bladder preservation is also discussed...

journal_title：European urology

authors： Calabrò F,Sternberg CN

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Nephroureterectomy (NUE) with a bladder cuff is the standard therapy for ureteral cancer. Based on an analysis of the literature and a retrospective study, this concept is questioned. METHODS:Between 1980 and 1991, 40 patients with ureteral tumors underwent surgery at the Krankenhaus der Barmherzigen Brüder ...

journal_title：European urology

authors： Leitenberger A,Beyer A,Altwein JE

更新日期：1996-01-01 00:00:00

abstract：:A case of sarcomatoid carcinoma of the renal pelvis is reported. The neoplasm showed polypoid configuration and was composed exclusively of plump, spindle and pleomorphic cells. Light microscopy did not reveal any epithelial differentiation of the neoplastic cells. Immunoperoxidase staining for keratins and for epithe...

journal_title：European urology

authors： Piscioli F,Bondi A,Scappini P,Luciani L

更新日期：1984-01-01 00:00:00

abstract：:The influence of magnesium chloride on various blood and urine parameters in calcium oxalate stone patients is studied. High dose magnesium therapy was found to increase urinary magnesium concentrations, whereas the oxalic acid concentration is reduced. The experiments support the statements on the role of magnesium i...

journal_title：European urology

authors： Brundig P,Berg W,Schneider HJ

更新日期：1981-01-01 00:00:00

abstract：:The Duckett transverse tube pedicle urethroplasty was used to repair the primary hypospadias of 190 boys over an 11-year period. The fistula rate was 34.4%. The majority of boys have obtained a satisfactory cosmetic and functional result with a single operation. ...

journal_title：European urology

authors： Dewan PA,Dinneen MD,Winkle D,Duffy PG,Ransley PG

更新日期：1991-01-01 00:00:00

abstract：:Neurogenic dyssynergia was treated with alpha-adrenergic blockers. Only 21 of 43 highly selected patients with residual urines and low flow rates continued therapy with phenoxybenzamine for more than 6 months, despite initial benefits. The causes of therapy discontinuation are discussed. A combination of 5 mg dibenzyl...

journal_title：European urology

authors： Vereecken RL,Van Poppel H,Boeckx G,Leruitte A

更新日期：1983-01-01 00:00:00

abstract：:In the past decade, increasing attention has been given to more systematic and quantitative ways of evaluating explicitly the impact of diseases and medical interventions on quality of life. A substantial part of this research pertained to the field of cancer where cure is not always possible and treatments are mostly...

journal_title：European urology

authors： Kiebert GM

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Laparoendoscopic single-site (LESS) surgery is challenging. To help overcome current technical and ergonomic limitations, the da Vinci robotic platform can be applied to LESS. OBJECTIVES:Our aim was to describe the surgical technique and to report the early outcomes of robotic LESS (R-LESS) radical prostate...

journal_title：European urology

authors： White MA,Haber GP,Autorino R,Khanna R,Forest S,Yang B,Altunrende F,Stein RJ,Kaouk JH

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Patients with metastatic urothelial carcinoma (mUC) who progress after platinum-based chemotherapy have had few treatment options and uniformly poor outcomes. Atezolizumab (anti-programmed death-ligand 1) was approved in the USA for cisplatin-ineligible and platinum-treated mUC based on IMvigor210, a phase 2...

journal_title：European urology

authors： Perez-Gracia JL,Loriot Y,Rosenberg JE,Powles T,Necchi A,Hussain SA,Morales-Barrera R,Retz MM,Niegisch G,Durán I,Théodore C,Grande E,Shen X,Wang J,Nelson B,Derleth CL,van der Heijden MS

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Treatment patterns for metastatic castration-resistant prostate cancer (mCRPC) have changed substantially in the last few years. In trial COU-AA-302 (chemotherapy-naïve men with mCRPC), abiraterone acetate plus prednisone (AA) significantly improved radiographic progression-free survival and overall survival...

journal_title：European urology

authors： de Bono JS,Smith MR,Saad F,Rathkopf DE,Mulders PFA,Small EJ,Shore ND,Fizazi K,De Porre P,Kheoh T,Li J,Todd MB,Ryan CJ,Flaig TW

更新日期：2017-04-01 00:00:00

abstract：:From 1980 to 1991, 236 patients with renal cell carcinoma were treated in our department. We studied the characteristics and the prognostic significance of 74 patients with incidental renal cancer in comparison with those with symptomatic tumors. The mean age of the patients was 59.8 years and the sex ratio 2 males/1 ...

journal_title：European urology

authors： Bretheau D,Lechevallier E,Eghazarian C,Grisoni V,Coulange C

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:To examine adherence and viability of human urothelial cells seeded on commercially available small intestine submucosa (SIS) specimens under serum-free conditions. MATERIALS AND METHODS:Before seeding, SIS was either washed with incubation medium or coated with collagen A, fibronectin, or pronectin. A poss...

journal_title：European urology

authors： Feil G,Christ-Adler M,Maurer S,Corvin S,Rennekampff HO,Krug J,Hennenlotter J,Kuehs U,Stenzl A,Sievert KD

更新日期：2006-12-01 00:00:00

abstract：:The records of children enrolled in the National Wilms' Tumor Study-3 who had Wilms' tumor and thrombosis into the renal vein were reviewed. There were 164 patients with gross involvement of the extrarenal vein and 47 patients with microscopic involvement, an incidence of 11.3% (211 of 1,865 evaluable patients). Two-y...

journal_title：European urology

authors： Ritchey ML,Othersen HB Jr,de Lorimier AA,Kramer SA,Benson C,Kelalis PP

更新日期：1990-01-01 00:00:00