Abstract：
OBJECTIVE:Nephroureterectomy (NUE) with a bladder cuff is the standard therapy for ureteral cancer. Based on an analysis of the literature and a retrospective study, this concept is questioned. METHODS:Between 1980 and 1991, 40 patients with ureteral tumors underwent surgery at the Krankenhaus der Barmherzigen Brüder in Munich. Tumoral stages were pTa and pTl in 62% of the patients; 37% showed an invasive carcinoma. Radical surgery (NUE with bladder cuff) was performed in 22 patients and conservative treatment (ureterocystoneostomy or end-to-end-anastomosis) in 13 patients. RESULTS:The median follow-up was 42 months in the conservative group and 59 months in the radical surgery group. A recurrence in the conservatively operated patients was observed only in primary invasive tumors (4/13), whereas none of the remaining patients had a recurrent tumor. In terms of time to progression and tumor-specific survival, there was a good correlation of the ureteral carcinoma according to grading and staging. In terms of survival, patients with superficial tumors run a similar course whether treated by conservative or radical surgery. CONCLUSION:The conservative treatment of patients presenting with superficial ureteral lesions seems to be a good alternative to radical surgery.
journal_name
Eur Uroljournal_title
European urologyauthors
Leitenberger A,Beyer A,Altwein JEdoi
10.1159/000473759subject
Has Abstractpub_date
1996-01-01 00:00:00pages
272-8issue
3eissn
0302-2838issn
1873-7560journal_volume
29pub_type
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