Abstract：
PURPOSE:To present the current status of laparoscopic radical prostatectomy (LRP) in Germany, Austria and Switzerland with respect to transferability, learning curve, and outcome. MATERIAL AND METHODS:The data of 5824 patients who underwent LRP in 18 centers by 50 urologists from March 1999 to August 2004 were analyzed retrospectively. Three centers performed more than 500, and six more than 250 cases. A transperitoneal descending technique with was used in 2701, a transperitoneal ascending in 1234, an extraperitoneal descending in 1814, and an extraperitoneal ascending modification in 75 cases. Specimen showed pT2 in 3535, pT3a in 1555, pT3b in 623, and pT4 in 111 cases. RESULTS:Mean operating time averaged 211 (131-292) minutes, with shorter duration of the extraperitoneal descending technique. Conversion to open surgery averaged 2.4 (0-14.1) %. Re-intervention rate amounted to 2.7 (0.3-7.7) %. Complication rate averaged 8.9 (1.8-10.8) % including bleeding (0.3-2.5%) and rectal lesion (1.5-2.5%). The rate of positive margins was 10.6 (3.2-18) % for pT2- and 32.7 (20-38.5) % for pT3a-tumors Continence after 12 months was 84.9 (72-94) %. Data about potency (7 centers) revealed 52.5 (35-67) % full erections following bilateral nerve preservation. 5 year-PSA recurrence rate (3 centers) was 8.6 (4-15.3) % for pT2-tumors and 17.5 (15-20.6) % for pT3a-stages. CONCLUSIONS:The results confirm the efficacy of the training program with safe transfer of LRP (i.e. low complication rate), however including all known problems of a retrospective study.
journal_name
Eur Uroljournal_title
European urologyauthors
Rassweiler J,Stolzenburg J,Sulser T,Deger S,Zumbé J,Hofmockel G,John H,Janetschek G,Fehr JL,Hatzinger M,Probst M,Rothenberger KH,Poulakis V,Truss M,Popken G,Westphal J,Alles U,Fornara Pdoi
10.1016/j.eururo.2005.10.003keywords:
subject
Has Abstractpub_date
2006-01-01 00:00:00pages
113-9issue
1eissn
0302-2838issn
1873-7560pii
S0302-2838(05)00665-2journal_volume
49pub_type
杂志文章,多中心研究相关文献
EUROPEAN UROLOGY文献大全abstract：BACKGROUND:Limited data exist to guide the use of androgen deprivation therapy (ADT) for men treated with radiation therapy (RT) after radical prostatectomy (RP). The optimal duration of ADT in this setting is unknown. OBJECTIVE:To determine if the duration of ADT influences clinical outcomes for men receiving post-RP...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2015.05.009
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:It remains unclear whether men selecting active surveillance (AS) are at increased risk of unfavorable longer term outcomes as compared with men who undergo immediate treatment. OBJECTIVE:To compare adverse pathologic outcomes in men with favorable-risk prostate cancer who underwent delayed prostatectomy af...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2015.09.032
更新日期：2016-04-01 00:00:00
abstract：:Pain is the most common symptom of any illness; the physician's therapeutic task is twofold: to discover and treat the cause of pain and the pain itself, whether or not the underlying cause is treatable, to provide relief and reduce the suffering caused by pain. Although we use the term of pain to define all sensation...
journal_title：European urology
pub_type： 指南,杂志文章,实务指引
doi：10.1016/s0302-2838(03)00321-x
更新日期：2003-10-01 00:00:00
abstract：:During a 15-year period, 34 patients with renal cell carcinoma extending into the inferior vena cava were submitted to radical ablative surgery at our institution. 8 patients had caval tumor thrombus (TT) extension at the level of the renal veins, 17 had infrahepatic, 8 retrohepatic and 1 atrial TT extension. Cavograp...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000472731
更新日期：1987-01-01 00:00:00
abstract：:A randomised trial of robotic and open prostatectomy commenced in October 2010 and is progressing well. Clinical and quality of life outcomes together with economic costs to individuals and the health service are being examined critically to compare outcomes. ...
journal_title：European urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.eururo.2013.10.031
更新日期：2014-03-01 00:00:00
abstract：:Although double-J stents (DJS) are used to reduce complications following extracorporeal shock wave lithotripsy (ESWL), there has recently been a tendency to limit their use because of complications. We retrospectively reviewed 351 patients with renal stones larger than 30 mm to determine the effectiveness and the com...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000474653
更新日期：1993-01-01 00:00:00
abstract：:Experimental unilateral spermatic cord torsion has been shown to induce both ipsilateral and contralateral intratesticular biochemical changes indicative of hypoxia. An experimental study was conducted to see whether the presence of the ipsilateral testicular tissue is necessary for the occurrence of the biochemical c...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000475039
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:To compare two new generation antimuscarinics at their recommended doses for treatment of overactive bladder syndrome (OAB). METHODS:A prospective, double blind, double-dummy, two-arm, parallel-group, 12-week study was conducted to compare the efficacy and safety of solifenacin 5 or 10 mg and tolterodine ext...
journal_title：European urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.eururo.2005.05.015
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND:The Rotterdam European Randomized Study of Screening for Prostate Cancer risk calculators (ERSPC-RCs) help to avoid unnecessary transrectal ultrasound-guided systematic biopsies (TRUS-Bx). Multivariable risk stratification could also avoid unnecessary biopsies following multiparametric magnetic resonance ima...
journal_title：European urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.eururo.2018.07.031
更新日期：2019-02-01 00:00:00
abstract：:The cancer-related 5-year survival was 80% in 79 patients with penile cancer treated at the Norwegian Radium Hospital from 1974 to 1985 (N0 = 61, N1-2 = 12, N3 = 6). Sentinel node biopsy (SLN) of the inguinal lymph nodes medial to the saphenous vein helps to identify patients with early regional spread. The survival f...
journal_title：European urology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and nec...
journal_title：European urology
pub_type： 杂志文章,评审
doi：10.1159/000019874
更新日期：1999-01-01 00:00:00
abstract：:Signet ring cell adenocarcinoma of the bladder is rare. Only 16 cases are recorded in the literature, although two meet the requirements for being considered of urachal origin. We present the third case of signet cell adenocarcinoma of urachal origin. ...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000472516
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Solifenacin, an effective, well-tolerated treatment for adult overactive bladder (OAB) symptoms, has not been evaluated in placebo-controlled paediatric clinical trials. OBJECTIVES:To evaluate the efficacy and safety of once-daily oral solifenacin suspension in OAB patients aged 5-<12 yr (children) and 12-<...
journal_title：European urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.eururo.2016.08.061
更新日期：2017-03-01 00:00:00
abstract：:Local effects of indwelling urinary catheters are poorly characterized. Latex catheter brands of various degrees of tissue toxicity were implanted into the urethra of 27 male piglets. The systemic hemodynamic states varied from normal to hypovolemia, where the circulation changes simulated the extracorporeal perfusion...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000472651
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:The objective of this research is to identify and determine the relative importance of dietary and environmental risk and risk reduction factors for prostate cancer mortality. MATERIALS AND METHODS:A multicountry ecologic approach was used in multivariate regression analyses with prostate cancer mortality ra...
journal_title：European urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.eururo.2003.08.018
更新日期：2004-03-01 00:00:00
abstract：INTRODUCTION:A total of 80-90% of all testicular masses are malignant germ cell tumors. Benign testicular lesions are recognized in approximately 10-20% enabling a testis-preserving surgery on the findings of frozen section examination (FSE). However, there are only sparse information with regard to the reliability of ...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/s0302-2838(02)00004-0
更新日期：2002-03-01 00:00:00
abstract：:We compared the history of 100 consecutive women complaining of incontinence with their urodynamic findings. The real urodynamic situation proved unpredictable on the basis of the medical history. A good correlation between history and urodynamics was found in 80% of the women complaining of stress incontinence. The i...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000472986
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND:Open partial nephrectomy (OPN) remains the gold standard for treatment of small renal masses (SRMs). Laparoscopic cryoablation (LCA) has provided encouraging outcomes. Robotic partial nephrectomy (RPN) represents a new promising option but is still under evaluation. OBJECTIVE:Compare the outcomes of RPN and...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2012.01.007
更新日期：2012-05-01 00:00:00
abstract：:Formalin-fixed, paraffin-embedded specimens from 91 primary transitional cell cancers (TCC) of the urinary bladder were stained with a monoclonal antibody to c-erb B-2 oncoprotein. Twelve percent (11/91) of the TCC stained for c-erb b-2 oncoprotein, and in 4% (4/91) of cases, the expression was graded as moderate or h...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000471706
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVES:We review important aspects of nanotechnology, and discuss the wide range of research and clinical applications of nanomedicine in the field of urology. There is particular emphasis on key clinical and pre-clinical studies to provide an update on recent and potential applications in the care of urological pa...
journal_title：European urology
pub_type： 杂志文章,评审
doi：10.1016/j.eururo.2007.04.065
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Immunochemotherapy (ICT) with interleukin-2 (IL-2) and interferon-alpha (IFNalpha) with a secondary effector (5-fluorouracil, 5 FU) is the only promising treatment for advanced renal cell carcinoma (RCC). With IFNalpha, besides the activation mechanisms of the immunosystem, a direct antitumor effect on tumor...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000052489
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:The prognostic significance of capsular incision (CapI) into tumor during radical prostatectomy (RP) with otherwise organ-confined disease remains uncertain. OBJECTIVE:To evaluate the impact of CapI into tumor on oncologic outcome. DESIGN, SETTING, AND PARTICIPANTS:A retrospective review of 8110 consecutiv...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2010.12.005
更新日期：2011-04-01 00:00:00
abstract：:12 patients have been treated for priapism between March 1973 and September 1977. Etiologic conditions have been found 9 times, leaving only 3 idiopathic priapisms. Treatment of choice consisted of 8 saphenocavernous shunts, achieving detumescence in 7 cases and preserving sexual potency in 5. The precocity of operati...
journal_title：European urology
pub_type： 杂志文章
doi：10.1159/000473100
更新日期：1979-01-01 00:00:00
abstract：OBJECTIVES:The aim of our study was to determine the value of duplex Doppler ultrasonography (DDU) in the patients' evolution with renal colic. The study of the resistive index (RI), difference of the RI (ARI) associated with a DDU intravesical recording (ureteral jets) were compared with renographic findings in renal ...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/s0302-2838(01)00005-7
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Limited data exist on long-term outcomes among men with prostate cancer (PCa) from population-based cohorts incorporating information on clinical risk category. OBJECTIVE:To assess 15-yr mortality for men with PCa treated with noncurative intent according to clinical stage, Gleason score (GS), serum levels ...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2012.08.001
更新日期：2013-01-01 00:00:00
abstract：CONTEXT:Given the highly variable behavior and clinical course of prostate cancer (PCa) and the multiple available treatment options, a personalized approach to oncologic risk stratification is important. Novel genetic approaches offer additional information to improve clinical decision making. OBJECTIVE:To review the...
journal_title：European urology
pub_type： 杂志文章,评审
doi：10.1016/j.eururo.2015.04.008
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE(S):The aim of our retrospective study was to determine if systematic placement of a posterior mesh, in addition to an anterior vesico-vaginal mesh, is necessary for laparoscopic treatment of pelvic organ prolapse. METHODS:A laparoscopic promontory sacral colpopexy was performed in 108 patients, including 55 ...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2004.01.004
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Well-designed randomized controlled trials (RCTs) have the potential to provide high-quality evidence to inform questions of therapy and prevention, but this potential is contingent on the use of appropriate methods and transparent reporting. OBJECTIVE:To systematically assess the quality of urology RCT rep...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2016.07.042
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Energy metabolism is important in cancer proliferation and progression, but its role in prostate cancer (PCa) remains unclear. OBJECTIVE:We explored whether single-nucleotide polymorphisms (SNPs) of genes involved in energy metabolic pathways are associated with PCa risk and prognosis, and whether antidiabe...
journal_title：European urology
pub_type： 杂志文章
doi：10.1016/j.eururo.2015.03.026
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:There is no sufficiently validated therapy for chronic pelvic pain syndrome (CPPS). OBJECTIVE:To investigate the effects of extracorporeal shock wave therapy (ESWT) in 60 patients suffering from CPPS. DESIGN, SETTING, AND PARTICIPANTS:Sixty patients suffering from CPPS for at least 3 mo were investigated i...
journal_title：European urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.eururo.2009.03.043
更新日期：2009-09-01 00:00:00
