Tissue engineering scaffolds using superstructures.

Abstract:

:Here, scaffolds as cell and tissue carriers are approached from an engineering point of view, emphasizing material superstructuring in the design of supports. Superstructure engineering provides optimal spatial and nutritional conditions for cell maintenance by the arrangement of structural elements (e.g. pores or fibres) so as to vary the order of cell to cell contact. This approach is illustrated in the design of several scaffolds: knitted fabrics as three-dimensional superstructures for optimized osteosynthesis implants, a new injectable open porous implant system, an angiopolar non-degradable ceramic cell carrier, and an injectable or microsurgically implantable entangled carrier system. The implications for tissue engineering are discussed.

journal_name

Biomaterials

journal_title

Biomaterials

authors

Wintermantel E,Mayer J,Blum J,Eckert KL,Lüscher P,Mathey M

doi

10.1016/0142-9612(96)85753-x

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

83-91

issue

2

eissn

0142-9612

issn

1878-5905

pii

014296129685753X

journal_volume

17

pub_type

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