Abstract:
:A case of choriocarcinoma in situ arising in an 11 week gestational placenta is reported. Histologically, a localized nodule, measuring 5 mm, of neoplastic trophoblastic proliferation appeared to arise directly from normal stem villi and projected into the intervillous space. The tumour was composed of biphasic cytotrophoblast and syncytiotrophoblast. No fetal elements were observed. The patient had a normal full-term spontaneous vaginal delivery 22 months after curettage and was free of disease without therapy at 32 months. This tumour provides evidence for an origin of choriocarcinoma from villous trophoblast. Our report illustrates the need to perform thorough microscopic examination of the products of conception, especially in the absence of a fetus or fetal parts.
journal_name
Histopathologyjournal_title
Histopathologyauthors
Fukunaga M,Ushigome S,Ishikawa Edoi
10.1111/j.1365-2559.1995.tb00313.xsubject
Has Abstractpub_date
1995-11-01 00:00:00pages
473-6issue
5eissn
0309-0167issn
1365-2559journal_volume
27pub_type
杂志文章相关文献
HISTOPATHOLOGY文献大全abstract:AIMS:Secretory carcinoma (SC) is a rare histological type of breast cancer, and ETV6-NTRK3 gene fusion is highly specific to it. The differential diagnoses of SC include acinic cell carcinoma (ACCA) and cystic hypersecretory carcinoma (CHC), as well as invasive ductal carcinoma (IDC). For patients with these rare but d...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12172
更新日期:2013-10-01 00:00:00
abstract::The post-transplant lymphoproliferative disorders represent a spectrum of life-threatening, generally Epstein-Barr virus-associated lymphoid proliferations which occur in the setting of exogenous immunosuppression following organ transplantation. Histopathological, phenotypic, genotypic and Epstein-Barr virus studies ...
journal_title:Histopathology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2559.1992.tb01007.x
更新日期:1992-05-01 00:00:00
abstract::Five antibodies, MT1 (CD43), UCHL1 (CD45RO), OPD4, poly-CD3 and beta F1, were assessed for their reactivity with 50 archival cases of T-cell lymphoma in formalin-fixed paraffin-embedded tissue. All cases had been previously characterized as T-cell lymphomas, and the histological types included 14 cases of small cerebr...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1991.tb00231.x
更新日期:1991-11-01 00:00:00
abstract::Expression of tenascin, type IV collagen and laminin during human intrahepatic bile duct development and in cholangiocarcinoma was examined by immunohistochemistry. In the developing hilar bile ducts, tenascin was expressed in the mesenchyme around the epithelial cells migrating from the ductal plate into the mesenchy...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1994.tb01570.x
更新日期:1994-08-01 00:00:00
abstract:AIMS:Follicular lymphoma (FL) in situ is defined as strongly bcl-2-positive B cells in germinal centres of morphologically inconspicuous lymph nodes. The prevalence and biological and clinical significance of this lesion are still not clear. Therefore we aimed at the detection of the prevalence of this phenomenon in an...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2011.03897.x
更新日期:2011-07-01 00:00:00
abstract::The author reports a case of a 53-year-old woman with a slowly growing thyroid papillary carcinoma. Microscopically the presence of adult adipose tissue was detected in numerous papillae. The recognition of this histological type as a new variety of papillary carcinoma is proposed. ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1986.tb02464.x
更新日期:1986-01-01 00:00:00
abstract::Two cases of pedunculated hepatocellular carcinoma are reported. One of these was known to have been present for 5 years. Both patients are alive 1 and 2 years after surgery though the former has developed a solitary bone metastasis. The literature on 30 previously published cases is reviewed and it is concluded that,...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1987.tb02645.x
更新日期:1987-04-01 00:00:00
abstract:AIMS:Most thymic carcinomas express the lymphocyte marker CD5 aberrantly. This study was performed to examine the role of the self-reactive CD5 antigen in thymic carcinoma. METHODS AND RESULTS:We examined CD5 expression in thymic carcinoma in relation to the lymphoid stroma. All cases of thymic carcinoma examined expr...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12742
更新日期:2016-02-01 00:00:00
abstract::Fine needle aspiration (FNA) cytology is a valuable aid to diagnosis and tumour staging in patients with non-Hodgkin's lymphoma. These tumours are often multicentric and involve sites such as the liver or the spleen which are not easily accessible to surgical biopsy. Particularly with splenic involvement, there is a d...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1987.tb02668.x
更新日期:1987-06-01 00:00:00
abstract:AIMS:Expression of tissue inhibitor of metalloproteinases-3 (TIMP-3) has been found to be decreased in several types of cancer by promoter gene hypermethylation. However, little is known regarding the silencing effect of TIMP3 promoter hypermethylation on gene and protein expression in endometrial carcinomas and its pr...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12047
更新日期:2013-03-01 00:00:00
abstract:AIMS:To investigate the pathology of colectomy specimens, from patients presenting with lower gastrointestinal haemorrhage, who had undergone preoperative mesenteric angiography. The angiography diagnoses ranged from active bleeding of unknown aetiology to angiodysplasia. METHODS AND RESULTS:The macroscopic and micros...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2005.02048.x
更新日期:2005-01-01 00:00:00
abstract:AIMS:Conjunctival pigmented lesions have characteristic clinical and histopathological appearances. Melanocytic pigmented lesions commonly occur in the conjunctiva, although they have not been previously reported in pterygium, a common lesion which originates from conjunctiva. Our aim was to evaluate the possibility of...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2006.02346.x
更新日期:2006-03-01 00:00:00
abstract:AIMS: Poorly differentiated thyroid carcinomas (PDTC) are an ongoing diagnostic challenge. Although the Turin consensus criteria for PDTC excluded consideration of oncocytic tumours, the World Health Organization (WHO) classification does recognise an oncocytic variant of conventional PDTC. The aims of this study were...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2012.04188.x
更新日期:2012-06-01 00:00:00
abstract::A clinicopathologic study of histiocytosis X in lymph nodes disclosed a special variant: primary eosinophilic granuloma of lymph nodes. This variant involves one or more lymph nodes, but does not infiltrate any other organs. Histologically, the infiltration of lymph nodes by histiocytosis X cells and eosinophils is si...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1980.tb02955.x
更新日期:1980-11-01 00:00:00
abstract:AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1046/j.1365-2559.1997.2310836.x
更新日期:1997-08-01 00:00:00
abstract:AIMS:To study the expression of the epithelial adhesion molecule E-cadherin and its associated proteins alpha and beta catenin in paraffin sections of normal ovaries, benign cystadenomas and ovarian carcinomas, and in immortalized normal ovarian surface epithelial cells and ovarian carcinoma cells in culture. METHODS ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1046/j.1365-2559.1998.00341.x
更新日期:1998-01-01 00:00:00
abstract:AIMS:This study has compared the tissue expression of the p53 tumour suppressor protein and DNA repair proteins APE1, hMSH2 and ERCC1 in normal, dysplastic and malignant lip epithelium. METHODS AND RESULTS:Morphological analysis and immunohistochemistry were performed on archived specimens of normal lip mucosa (n=15),...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2011.03756.x
更新日期:2011-02-01 00:00:00
abstract:AIMS:We aimed to define the clinicopathological characteristics of 29 primary sinonasal diffuse large B cell lymphoma (DLBCLsn ) in a series of 240 cases of DLBCL not otherwise specified [DLBCLall (NOS) ], including DLBCLsn training set (n = 11) and validation set (n = 18), and DLBCLnon-sn (n = 211). METHODS AND RESUL...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.13106
更新日期:2017-03-01 00:00:00
abstract:AIMS:Two-hundred and four accessible cases of malignant melanoma from the Grampian region of Scotland, collected over a period of 4 years, were studied for standard prognostic indicators for comparison with microvessel density. METHODS AND RESULTS:The range of tumour thickness varied from in-situ melanoma to 14.8 mm. ...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2005.02193.x
更新日期:2005-08-01 00:00:00
abstract::We have investigated the immunohistochemical expression of p53 protein in 96 cases of non-Hodgkin's lymphoma using a panel of five antibodies. Positive neoplastic cells were found in 30 (31.2%) cases, which could be divided into two groups according to their patterns of reactivity with the different antibodies; i.e. t...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1993.tb00067.x
更新日期:1993-01-01 00:00:00
abstract:AIMS:To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic liposarcoma. Pleomorphic liposarcoma is a very rare variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts showing peculiar epithelial-like features that can be confu...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2005.02064.x
更新日期:2005-03-01 00:00:00
abstract::Two cases of papillary and cystic neoplasm of the pancreas (PCN) occurring in 17 and 21 year old women are reported with ultrastructural and immunohistochemical findings. A review of the English literature shows that although potentially malignant, PCN, which occurs mainly in young women, is amenable to surgical cure....
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1985.tb02971.x
更新日期:1985-01-01 00:00:00
abstract:AIMS:Owing to their close embryological relationship, soft tissue perineurioma and meningioma may closely mimic each other, not only histologically but also by immunohistochemistry. We aimed to compare the frequency of perineurial marker expression in these two entities, and to determine whether somatostatin receptor 2...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.12366
更新日期:2014-07-01 00:00:00
abstract::Hodgkin lymphoma (HL) is an unusual malignancy in that the tumour cells, the Hodgkin and Reed-Sternberg (HRS) cells, are a minor component of the tumour mass, the bulk of which is a mixed cellular infiltrate. There is compelling evidence that HRS cells are clonal B cells that have lost their B cell phenotype. Mature B...
journal_title:Histopathology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2559.2010.03705.x
更新日期:2011-01-01 00:00:00
abstract:AIMS:Maspin, a protein belonging to the serpin superfamily, is the product of a tumour suppressor gene. Tissue distribution studies have shown maspin expression in normal mammary epithelial cells, in the placenta, prostate, thymus, testis, oral cavity, small intestine, skin, and cornea. Maspin is expressed but down-reg...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2005.02141.x
更新日期:2005-05-01 00:00:00
abstract:AIMS:There is evidence that four or five gastric cancer biopsies are required for accurate HER2 interpretation. However, the number of biopsies that need to be taken to reach this number of viable cancer biopsies is without evidence. This study aimed to address this gap by assessing the number of biopsies required to g...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.13816
更新日期:2019-05-01 00:00:00
abstract::Thirty kidney tumours of various histological type were histochemically investigated under the light microscope by means of the ABC-method. We used four biotinylated lectins which are known to bind also to normal renal tubular epithelial cells of different nephron segments. The nuclear grade, the histological growth p...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1985.tb02783.x
更新日期:1985-10-01 00:00:00
abstract:AIMS:Mucinous tubular and spindle cell carcinoma (MTSC) of the kidney is a distinct entity characterized by bland tightly packed elongated tubules and spindle cells with low nucleolar grade in a basophilic mucinous stroma. Several case studies have reported MTSC with high-grade features and have brought into question w...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/his.13298
更新日期:2017-11-01 00:00:00
abstract:AIMS:Nitric oxide (NO), produced by inducible NO synthase (iNOS), has been suggested to cause oxidative stress, leading to 8-hydroxydeoxyguanosine (8-OHdG) accumulation and subsequent transversion mutation of DNA. The aim was to evaluate iNOS expression and the status of oxidative stress in nasopharyngeal carcinoma (NP...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.2007.02920.x
更新日期:2008-01-01 00:00:00
abstract::HLA-DR expression was examined in 50 consecutive primary cutaneous malignant melanomas with a Breslow depth greater than 2 mm using two well-characterized monoclonal antibodies which detect fixation-resistant epitopes. In 31 of these cases (62%) a subpopulation of tumour cells was reactive, although there was consider...
journal_title:Histopathology
pub_type: 杂志文章
doi:10.1111/j.1365-2559.1992.tb01011.x
更新日期:1992-05-01 00:00:00