Abstract:
:Work with non-human primates had previously demonstrated that the mid-dorsolateral frontal cortex, which comprises cytoarchitectonic areas 46 and 9, plays a critical role in the performance of non-spatial self-ordered working memory tasks, whereas the immediately adjacent posterior dorsolateral frontal cortex (area 8) is critical for the learning and performance of visual conditional associative tasks. The present study used positron emission tomography with magnetic resonance imaging to demonstrate the existence, within the human brain, of these two functionally distinct subdivisions of the lateral frontal cortex. These findings provide direct evidence that, just as the monkey brain, the human lateral frontal cortex is functionally heterogeneous and that comparable anatomical areas underlie similar functions in the two species.
journal_name
Proc Natl Acad Sci U S Aauthors
Petrides M,Alivisatos B,Evans AC,Meyer Edoi
10.1073/pnas.90.3.873subject
Has Abstractpub_date
1993-02-01 00:00:00pages
873-7issue
3eissn
0027-8424issn
1091-6490journal_volume
90pub_type
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