Abstract：
:Primates can gradually increase or decrease H-reflex amplitude in one leg when reward depends on that amplitude. The magnitude of change varies greatly from animal to animal. This study sought to define the factors that control this magnitude. It evaluated the influence of animal age, muscle size (absolute and relative), background electromyographic activity (EMG) level, M response amplitude, initial H-reflex amplitude, performance intensity, and behavior of the contralateral leg. Fifty-four animals (Macaca nemestrina) underwent operant conditioning of the triceps surae H-reflex in one leg (the trained leg). Twenty-eight were rewarded for larger H-reflexes (HRup animals), and 26 were rewarded for smaller H-reflexes (HRdown animals). In the HRup animals, H-reflex amplitude in the trained leg rose to an average final value of 177% of its initial amplitude. Magnitude of increase varied widely across animals. Nine animals rose to 120-140%, 11 to 160-240%, three to 300% or more, and five remained within 20% of initial amplitude. In the HRdown animals, H-reflex amplitude in the trained leg decreased to an average of 69% of initial amplitude. Magnitude of decrease varied widely. Five animals decreased to 20-40%, seven to 40-60%, six to 60-80%, and eight remained within 20% of initial amplitude. Animal age, as assessed by weight, markedly affected HRdown conditioning, but not HRup conditioning. Heavy HRdown animals (> or = 6 kg) were more successful than light HRdown animals (< 6 kg). Thirteen of 14 heavy animals and only five of 12 light animals decreased to less than 80% of initial amplitude.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Wolpaw JR,Herchenroder PA,Carp JSdoi
10.1007/BF00228815subject
Has Abstractpub_date
1993-01-01 00:00:00pages
31-9issue
1eissn
0014-4819issn
1432-1106journal_volume
97pub_type
杂志文章abstract：:The topographical mapping of glial fibrillary acidic protein (GFAP)-immunoreactivity was performed in coronal serial sections of the rat mesencephalon, rhombencephalon and spinal cord. Relative to a background of poor or moderate overall staining of the mesencephalon, the interpeduncular nucleus, substantia nigra and ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230695
更新日期：1989-01-01 00:00:00
abstract：:Two components of long-term potentiation (LTP) are distinguished with extracellular recording electrodes: a synaptic and an EPSP-Spike (E-S) component. The latter consists of the enhancement produced in the population spike amplitude in excess of that predicted by EPSP potentiation alone. The experiments carried out i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229331
更新日期：1990-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0964-6
更新日期：2007-08-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231244
更新日期：1990-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2000-11-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2009-03-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231171
更新日期：1991-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2014-06-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236784
更新日期：1979-03-09 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1823-8
更新日期：2004-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：1988-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00221-014-3863-7
更新日期：2014-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/BF00227650
更新日期：1996-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0189-5
更新日期：2006-03-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：1999-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：1999-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2001-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050765
更新日期：1999-06-01 00:00:00
