Beta-adrenergic modulation of rat brain insulin receptor activity in normal and hyperglycaemic conditions.

Abstract:

:The [125I]Insulin binding and receptor kinase activity were assessed in rat brain in the presence of 10 microM concentrations of the beta agonist isoproterenol. While insulin binding remained unaltered, beta agonist treatment enhanced significantly receptor kinase activity in control and hyperglycaemic conditions. Antihyperglycaemic effects of isoproterenol were discussed in relation to adrenergic effects on insulin action in brain.

journal_name

Indian J Exp Biol

authors

Ansari MA,Gupta G,Baquer NZ

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

92-4

issue

2

eissn

0019-5189

issn

0975-1009

journal_volume

32

pub_type

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