[Gold treatment of progressive chronic polyarthritis--a clinical study].

abstract：:Heberden nodes affect mainly middle-aged women. Inheritance is autosomal dominant in female and autosomal recessive in male patients. We report the case of a young man who presented already with 12 years of age with pain in the distal finger joints. There were no other clinical or serological signs for other rheumatoi...

journal_title：Zeitschrift fur Rheumatologie

authors： Rascu A,Kraetsch HG,Grünke M,Kalden JR,Manger B

更新日期：1999-04-01 00:00:00

abstract：:Three new findings are reviewed that help to understand the mechanisms of action of anti-rheumatic gold drugs, such as disodium aurothiomalate (Na2Au(I)TM): i) We found that Na2Au(I)TM selectively inhibits T-cell receptor-mediated antigen recognition by murine CD4+ T-cell hybridomas specific for antigenic peptides con...

journal_title：Zeitschrift fur Rheumatologie

authors： Griem P,Gleichmann E

更新日期：1996-09-01 00:00:00

abstract：:This article gives a comprehensive overview of diffuse interstitial lung diseases especially those associated with connective tissue diseases. Interstitial lung diseases (ILD) represent a heterogeneous group of diseases of very different and partially unknown etiologies. Therefore, an exact classification of the ILD i...

journal_title：Zeitschrift fur Rheumatologie

authors： Koller HK,Burghuber OC

更新日期：2003-04-01 00:00:00

abstract：:In a sequential study the pathogenesis of chronic polyarthritis occurring spontaneously in MRL mice was analysed by light microscopy. A total of 128 MRL mice of both substrains (MRL/Mp-lpr/lpr and +/+) and different age groups was studied. In 50 lpr/lpr mice, tinctorial and histochemical methods were applied for the i...

journal_title：Zeitschrift fur Rheumatologie

authors： Hewicker M,Garcés LH,Kromschröder E,Trautwein G

更新日期：1988-07-01 00:00:00

abstract：:Fractalkine (CX3CL1), so far the only member of the CX3C class of chemokines, and its receptor, CX3CR1, are strongly expressed in the chronically inflamed synovial tissue of patients with rheumatoid arthritis (RA). Due to the specific binding of Fractalkine to its receptor, many proinflammatory reactions involved in t...

journal_title：Zeitschrift fur Rheumatologie

authors： Blaschke S,Müller GA

更新日期：2008-09-01 00:00:00

abstract：:Assessment of disease consequences (outcome) requires reliable, valid, and sensitive instruments. Psychometrically sound generic health-status instruments such as the SF-36 have been validated for many languages and are available in German. Instead, most disease specific instruments have been developed in English and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Stucki G,Stucki S,Sangha O

更新日期：1997-10-01 00:00:00

abstract：:409 unselected outpatients were asked standardized expert system questions on the medical history of joint complaints. An average number of 30.4 +/- 6.6 out of 60 questions with 346 different answers were asked in a mean time of 20.1 +/- 6.6 min. This time, required for the questions to be displayed on the computer sc...

journal_title：Zeitschrift fur Rheumatologie

authors： Schewe S,Krüger K,Herzer P,Schattenkirchner M

更新日期：1991-07-01 00:00:00

abstract：:Because it is a systemic disorder, rheumatoid arthritis (RA) is known to predispose affected individuals to other organ manifestations as well as arthritic problems. The serious complications include pericarditis, pulmonary and cutaneous nodules, episcleritis, and rheumatoid vasculitis. Of late, a significantly increa...

journal_title：Zeitschrift fur Rheumatologie

authors： Whelan P

更新日期：2006-10-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：:Rheumatic diseases are among the most common chronic inflammatory disorders. Besides severe pain and progressive destruction of the joints, rheumatoid arthritis (RA), spondyloarthritides (SpA) and psoriatic arthritis (PsA) impair working ability, reduce quality of life and if treated insufficiently may enhance mortali...

journal_title：Zeitschrift fur Rheumatologie

authors： Häupl T,Skapenko A,Hoppe B,Skriner K,Burkhardt H,Poddubnyy D,Ohrndorf S,Sewerin P,Mansmann U,Stuhlmüller B,Schulze-Koops H,Burmester GR

更新日期：2018-05-01 00:00:00

abstract：:Rheumatoid vasculitis usually occurs on the background of seropositive rheumatoid arthritis, although in rare cases the patients can be seronegative. We report a woman with seronegative rheumatoid arthritis with rheumatoid vasculitis who developed toxic epidermal necrolysis involving most of her body surface area, whi...

journal_title：Zeitschrift fur Rheumatologie

authors： Chowdhury AC,Misra DP,Patro PS,Agarwal V

更新日期：2016-03-01 00:00:00

abstract：:Superficial heat and cold are commonly used therapeutic methods in patients with rheumatoid arthritis. Both procedures have analgesic effect. In 30 inpatients with rheumatoid arthritis the pain threshold was measured before and after warm bath and ice massage. Rheumatoid patients had significantly lower pain threshold...

journal_title：Zeitschrift fur Rheumatologie

authors： Curković B,Vitulić V,Babić-Naglić D,Dürrigl T

更新日期：1993-09-01 00:00:00

abstract：:278 patients with ankylosing spondylitis have been studied in order to find a basis for prognosis by setting a mobility function index of the vertebral column. This index does not depend on manifestation age or on the blood sedimentation rate. It increases with progression of x-ray findings. A coincidence of impaired ...

journal_title：Zeitschrift fur Rheumatologie

authors： Schöffel J,Pohl W

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Clinical observation suggests a frequent coincidence of back pain (BP) and fibromyalgia (FMA). Based on data from a population survey on back pain we studied the hypothesis of FMA being a frequent underlying condition of BP. We additionally studied the association of the severity of back pain and both chroni...

journal_title：Zeitschrift fur Rheumatologie

authors： Hüppe A,Brockow T,Raspe H

更新日期：2004-02-01 00:00:00

abstract：:A 28-year-old female patient had load-dependent pain of the left knee. MRI showed an osteochondral defect of the medial condyle based on extensive osteonecrosis of the femoral and tibial bone. An association with a prior steroid treatment after cervical injury is most likely. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Steinhagen J,Rüther W

更新日期：2004-06-01 00:00:00

abstract：:In order to reduce the prognostically relevant time interval between the initial manifestation of a rheumatic and musculoskeletal disease and diagnosis as well as the consecutive initiation of an appropriate treatment, several rheumatological centers in Germany have improved the access to initial rheumatologic evaluat...

journal_title：Zeitschrift fur Rheumatologie

authors： Benesova K,Lorenz HM,Lion V,Voigt A,Krause A,Sander O,Schneider M,Feuchtenberger M,Nigg A,Leipe J,Briem S,Tiessen E,Haas F,Rihl M,Meyer-Olson D,Baraliakos X,Braun J,Schwarting A,Dreher M,Witte T,Assmann G,Hoeper

更新日期：2019-10-01 00:00:00

abstract：:Many rheumatological diseases are either caused by specific known proteins, such as antibodies or mediated by a plethora of cytokines. Both the unspecific immunosuppressive therapy and the specific action of biologics usually require time to be effective; therefore, extracorporeal forms of treatment are increasingly b...

journal_title：Zeitschrift fur Rheumatologie

authors： Boser M,Kielstein JT

更新日期：2016-12-01 00:00:00

abstract：:Big data analysis raises the expectation that computerized algorithms may extract new knowledge from otherwise unmanageable vast data sets. What are the algorithms behind the big data discussion? In principle, high throughput technologies in molecular research already introduced big data and the development and applic...

journal_title：Zeitschrift fur Rheumatologie

authors： Bonin-Andresen M,Smiljanovic B,Stuhlmüller B,Sörensen T,Grützkau A,Häupl T

更新日期：2018-04-01 00:00:00

abstract：:In rheumatologic diseases magnet resonance imaging (MRI) is capable of depicting early inflammatory changes which are frequently missed by other imaging modalities. New MRI protocols and hardware, primarily whole-body MRI and low-field extremity MRI facilitate the use of MRI in rheumatology patients. The increasing nu...

journal_title：Zeitschrift fur Rheumatologie

authors： Buchbender C,Schneider M,Ostendorf B

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:The aim in this study was to determine whether solute carrier family 22, member 4 (SLC22A4), and runt-related transcription factor 1 (RUNX1) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA) in populations of different ethnicities. METHODS:We conducted a literature search using th...

journal_title：Zeitschrift fur Rheumatologie

authors： Lee YH,Bae SC,Kim JH,Seo YH,Choi SJ,Ji JD,Song GG

更新日期：2015-05-01 00:00:00

abstract：:The assessment of off-label medications is one of the most common reasons for assessment of drugs for individual patients in the German medical services. Tension is not uncommon because of great expectations of patients and doctors on the one hand and the requirements of the law on the other. They often do not match. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grell L,Rieger M

更新日期：2012-02-01 00:00:00

abstract：:The enzyme poly-(ADP-ribose) polymerase (PARP) is localized within the cell nucleus and catalyzes DNA-repair. During programmed cell death (apoptosis), PARP is enzymatically cleaved. Detection of the cleavage products is characteristic for apoptosis. In patients with systemic lupus erythematosus (SLE), the highly orde...

journal_title：Zeitschrift fur Rheumatologie

authors： Böhm I

更新日期：2006-10-01 00:00:00

abstract：:A few days after the SARS-CoV-2 infection was declared a pandemic, the German Society for Rheumatology (DGRh) compiled first recommendations for the care of patients with inflammatory rheumatic diseases (IRD). These first recommendations were based on an expert consensus and were largely non-evidence-based. Now that t...

journal_title：Zeitschrift fur Rheumatologie

authors： Schulze-Koops H,Iking-Konert C,Leipe J,Hoyer BF,Holle J,Moosig F,Aries P,Burmester G,Fiehn C,Krause A,Lorenz HM,Schneider M,Sewerin P,Voormann A,Wagner U,Krüger K,Specker C,Kommission Pharmakotherapie.,Vorstand der De

更新日期：2020-09-01 00:00:00

abstract：:Low back pain (LBP) in patients with rheumatoid arthritis (RA) has so far been of little concern in clinical investigations. The main focus of scientific publications on spinal problems in RA was the cervical spine. In a recent study, we could demonstrate that LBP in RA patients leads to a significantly higher degree ...

journal_title：Zeitschrift fur Rheumatologie

authors： Kothe R

更新日期：2017-12-01 00:00:00

abstract：:Aortic aneurysm and dissection are rare complications of systemic lupus erythematosus (SLE). The incidence, etiology, risk factors, and outcomes of this entity were largely unknown.The study materials were based on the publications of aortic aneurysm or dissection due to SLE published between 2000 and 2017.A total of ...

journal_title：Zeitschrift fur Rheumatologie

authors： Yuan SM

更新日期：2019-04-01 00:00:00

abstract：:The diagnosis of pyoderma gangraenosum was previously made as a diagnosis of exclusion. For this reason repeated attempts have been made in recent years to develop new diagnostic scores, whereby the typical clinical and anamnestic aspects were usually taken into account and the relevant differential diagnoses were exc...

journal_title：Zeitschrift fur Rheumatologie

authors： Dissemond J

更新日期：2018-12-01 00:00:00

abstract：:Binding of gold to serum proteins of patients treated with Na-aurothiomalate (AM), gold keratinate (GK) and triethylphosphine gold (PG) was compared. In addition the pattern of distribution of gold in serum of healthy donors after in vitro incubation with these compounds and with tetrachlorogoldacid (GC) was studied. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Herrlinger JD,Weikert W

更新日期：1982-09-01 00:00:00

abstract：:Bone metabolic homeostasis is regulated by a number of hormones and local modulators, and the study of these factors has been of major help in our understanding of bone disease. However, these parameters do not, in a strict sense reflect the metabolic and biochemical changes in the diseased bone tissue. Thus, there is...

journal_title：Zeitschrift fur Rheumatologie

authors： Tohmé JF,Seibel MJ,Silverberg SJ,Robins SP,Bilezikian JP

更新日期：1991-05-01 00:00:00

abstract：:The German Rheuma-Liga as the largest patient organisation presents the different ways of informing patients. Patient- education-programs are presented, with a program focussing on social and psychological issues in particular. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Cattelaens K

更新日期：2003-01-01 00:00:00

abstract：:A set of early diagnostic (ED) criteria comprising clinical data, ESR, radiological spinal signs, and the risk factor HLA B27 was evaluated after 5 and 10 years in a follow-up of 54 patients with an initial diagnosis of possible ankylosing spondylitis (AS). After 10 years 32 patients (59%) had developed definite AS ac...

journal_title：Zeitschrift fur Rheumatologie

authors： Mau W,Zeidler H,Mau R,Majewski A,Freyschmidt J,Stangel W,Deicher H

更新日期：1990-03-01 00:00:00