[Early recognition and screening consultation: a necessary way to improve early detection and treatment in rheumatology? : Overview of the early recognition and screening consultation models for rheumatic and musculoskeletal diseases in Germany].

abstract：:Eight human femoral heads, surgically removed from patients with the clinical diagnosis: coxarthrosis or necrosis, were examined. In six of these we found severe arthrosis combined with synovitis and pannus formation. The pannus appeared as granulation tissue or fibrous connective tissue covering the surface of the ca...

journal_title：Zeitschrift fur Rheumatologie

authors： Pataki A,Lothe K,Spycher MA,Rüttner JR,Cserhati MD

更新日期：1983-11-01 00:00:00

abstract：:Osteoporosis is an age-related systemic disease leading to increased bone fragility. The vertebral bodies of the transitional area between the thoracic and lumbar spine are often involved. A large number of unreported or late-diagnosed fractures have to be assumed. If risk factors such as advanced age or comorbidities...

journal_title：Zeitschrift fur Rheumatologie

authors： Boluki D

更新日期：2011-01-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a mainstay in musculoskeletal imaging. The term"bone marrow edema" is frequently used for describing the radiological findings, especially with respect to rheumatic diseases. The referring physician should be aware that this term has a purely descriptive character and the pathophysi...

journal_title：Zeitschrift fur Rheumatologie

authors： Hamer OW,Kriegsmann J

更新日期：2012-01-01 00:00:00

abstract：:In small vessel vasculitides, imaging studies aid in determining disease extent and activity, localization for biopsy, and for disease monitoring. They do not directly delineate the vasculitic lesion. Imaging studies focus on the upper and lower respiratory tract. Cranial magnetic resonance imaging (MRI) shows upper r...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmidt WA,Both M,Reinhold-Keller E

更新日期：2006-11-01 00:00:00

abstract：:Biochemical studies of rats with mycoplasma arthritis revealed new findings in pathogenesis and pathophysiology. Preliminary examinations showed that mycoplasmas release specific endonucleases and exonucleases. In evaluating the isoenzymes of the lactate dehydrogenases, malate dehydrogenases as well as of the esterase...

journal_title：Zeitschrift fur Rheumatologie

authors： Klein G

更新日期：1975-05-01 00:00:00

abstract：:Childhood onset rheumatic and musculoskeletal diseases often continue into adulthood. These diseases are associated with a high risk of permanent disability and impairment in the quality of life of people affected. Adolescence and young adulthood represent a particular risk phase for an unfavorable long-term outcome. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Minden K,Schalm S

更新日期：2016-08-01 00:00:00

abstract：:A central problem of persons with chronic polyarthritis is the necessary adaptation to deteriorating health in everyday activities. Difficulties and burdens of this adaptation are parts of the study undertaken in the Unna Model, which was part of the research on "Local Services for CP-Patients". In the first part two ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grunow-Lutter V,Grunow D

更新日期：1992-01-01 00:00:00

abstract：:Fractalkine (CX3CL1), so far the only member of the CX3C class of chemokines, and its receptor, CX3CR1, are strongly expressed in the chronically inflamed synovial tissue of patients with rheumatoid arthritis (RA). Due to the specific binding of Fractalkine to its receptor, many proinflammatory reactions involved in t...

journal_title：Zeitschrift fur Rheumatologie

authors： Blaschke S,Müller GA

更新日期：2008-09-01 00:00:00

abstract：:An appropriate treatment of elderly rheumatic patients implements comprehensive diagnostics and exclusion diagnostics of e.g. coronary heart disease, osteoporosis, renal failure, diabetes mellitus type 2 and thyroid gland dysfunction. Furthermore, the complex disease situation might require the integration of other fa...

journal_title：Zeitschrift fur Rheumatologie

authors： Lakomek HJ,Brabant T,Lakomek M,Lüttje D

更新日期：2013-08-01 00:00:00

abstract：:Biomarkers form the basis for patient stratification and the development of individualized treatment strategies. As the understanding of the pathophysiological processes underlying rheumatic diseases increases, novel biomarkers will become available and established markers can be used more efficiently. Autoantibodies ...

journal_title：Zeitschrift fur Rheumatologie

authors： Scherer HU,Burmester GR,Häupl T

更新日期：2013-02-01 00:00:00

abstract：:Performing histo-morphologic studies of knee joints in several hundred mice of the strains C57 black, STR/1N and MAGf, showing a disposition for spontaneous osteo-arthrosis, we found tentative reparative processes in many cases. There was a proliferation of cartilage and of the synovial membrane, mostly in the periphe...

journal_title：Zeitschrift fur Rheumatologie

authors： Wilhelmi G,Schneider-Faust R

更新日期：1984-09-01 00:00:00

abstract：:Assessment of disease consequences (outcome) requires reliable, valid, and sensitive instruments. Psychometrically sound generic health-status instruments such as the SF-36 have been validated for many languages and are available in German. Instead, most disease specific instruments have been developed in English and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Stucki G,Stucki S,Sangha O

更新日期：1997-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased mortality, largely as a consequence of cardiovascular (CV) disease. Studies found relative risk ratios of 2 for myocardial infarction in RA and up to 7 for myocardial infarction in SLE patients.Beyond the traditional CV risk...

journal_title：Zeitschrift fur Rheumatologie

authors： Fischer-Betz R,Halle M,Schneider M

更新日期：2010-10-01 00:00:00

abstract：:Activated monocytes/macrophages secrete monokines, regulatory proteins which are capable of initiating and maintaining immune processes as well as having an effect on other non immunocompetent cells. In rheumatoid arthritis the monokine Interleukin-1 (IL-1) was detected in the synovial fluid. IL-1 activates immunocomp...

journal_title：Zeitschrift fur Rheumatologie

authors： Hermann E,Müller W

更新日期：1985-09-01 00:00:00

abstract：:Ocular manifestations of systemic vasculitides are extraordinarily pleomorph and have been described for many decades. In the introduction the special interaction of the immune system and the eye is outlined. Thereafter diagnostic procedures of patients suffering from systemic vasculitides are shown from an ophthalmol...

journal_title：Zeitschrift fur Rheumatologie

authors： Nölle B

更新日期：2001-08-01 00:00:00

abstract：:Superficial heat and cold are commonly used therapeutic methods in patients with rheumatoid arthritis. Both procedures have analgesic effect. In 30 inpatients with rheumatoid arthritis the pain threshold was measured before and after warm bath and ice massage. Rheumatoid patients had significantly lower pain threshold...

journal_title：Zeitschrift fur Rheumatologie

authors： Curković B,Vitulić V,Babić-Naglić D,Dürrigl T

更新日期：1993-09-01 00:00:00

abstract：:The biochemical defect leading to alcaptonuria is well known. However, the pathogenesis of ochronotic arthropathy is poorly understood. The present ultrastructural study elucidated the localization of ochronotic pigment in the articular cartilage and evidence was found that suggests a pathway for cartilage destruction...

journal_title：Zeitschrift fur Rheumatologie

authors： Mohr W,Wessinghage D,Lenschow E

更新日期：1980-03-01 00:00:00

abstract：:In recent years the great progress in knowledge on bone cell biology has allowed identification of molecular structures that can be targeted with pinpoint precision (druggable targets). Osteoclasts are regulated via the RANK-RANK-ligand (RANKL) signaling pathway and osteoblasts via the Wnt signaling pathway, both of w...

journal_title：Zeitschrift fur Rheumatologie

authors： Knauerhase A,Willenberg HS

更新日期：2016-06-01 00:00:00

abstract：:Behçet's disease (BD) is a recurrent, multisystemic, inflammatory blood vessel disorder that can result in mouth, genital, and skin ulcers; arthritis; and eye and intestinal inflammation. We describe a 21-year-old Korean female patient with intestinal BD refractory to conventional medical treatment and biologic drugs....

journal_title：Zeitschrift fur Rheumatologie

authors： Kim HJ,Kim KT,Lee SG,Kim Y

更新日期：2020-09-01 00:00:00

abstract：:Conventional radiography, ultrasonography (US), magnetic resonance imaging (MRI), computed tomography, and scintigraphy are imaging techniques in use for rheumatoid arthritis (RA). Conventional radiography of the hands and the forefeet should be performed every 6 to 12 months in the first two years, and every 12 to 24...

journal_title：Zeitschrift fur Rheumatologie

authors： Kellner H,Schmidt W,Rau R

更新日期：2005-11-01 00:00:00

abstract：:By means of the 99m-Tc-pertechnitate joint scintigraphy the authors try to document the effect of antirheumatic drugs in 62 patients with rheumatoid arthritis. By measuring the changes of the synovial blood circulation, conclusions are drawn as to the degree of inflammation. When trying to make a quantitative assessme...

journal_title：Zeitschrift fur Rheumatologie

authors： Kafarnik D,Semmler U,Pfannenstiel P,Miehlke K

更新日期：1981-03-01 00:00:00

abstract：:MicroRNAs are small non-coding RNAs which are crucial for the fine regulation of gene expression. Recent results suggest that these molecules display multifaceted functions in B-cells and T-cells in rheumatic inflammatory diseases. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Wittmann J,Jäck HM,Mashreghi MF

更新日期：2011-08-01 00:00:00

abstract：:Aortic aneurysm and dissection are rare complications of systemic lupus erythematosus (SLE). The incidence, etiology, risk factors, and outcomes of this entity were largely unknown.The study materials were based on the publications of aortic aneurysm or dissection due to SLE published between 2000 and 2017.A total of ...

journal_title：Zeitschrift fur Rheumatologie

authors： Yuan SM

更新日期：2019-04-01 00:00:00

abstract：:Twelve patients with osteoarthrosis were locally treated with Felbinac Gel (biphenyl acetic acid (BPAA) 3%) three times daily for 14 days (five patients), 28 days (six patients) or 42 days (one patient) before elective knee joint surgery. BPAA plasma concentrations as of the seventh day of treatment were steady at bet...

journal_title：Zeitschrift fur Rheumatologie

authors： Bolten W,Waldorf-Bolten E,Sarfert D,Lehmann W,Miehlke W

更新日期：1990-11-01 00:00:00

abstract：:Musculoskeletal ultrasonography (US) is an established and validated imaging technique in rheumatology. Ultrasonography is able to directly visualize soft tissue pathologies such as synovial tissue changes. Pathological findings in superficial cartilage, bone lesions and synovial tissue changes in the context of rheum...

journal_title：Zeitschrift fur Rheumatologie

authors： Tamborrini G,Backhaus M,Schmidt W,Ziswiler HR

更新日期：2010-12-01 00:00:00

abstract：:Wegener's granulomatosis, Churg-Strauss syndrome and analgesics intolerance syndrome with polyps demonstrate non-specific manifestations in the head and neck region. These symptoms can often lead to early diagnosis and initiation of the correct therapy. However, symptoms are often ambiguous and many rare differential ...

journal_title：Zeitschrift fur Rheumatologie

authors： Laudien M,Ambrosch P,Till A,Podschun R,Lamprecht P

更新日期：2008-09-01 00:00:00

abstract：:Systemic sclerosis (SSc, scleroderma) is a multisystem disease with a bad prognosis. No drugs have been shown to cure this disease. In view of its pathogenesis, in which immune responses are presumed to play an important role, immune suppressive therapies are widely applied in the treatment of SSc. Recent placebo-cont...

journal_title：Zeitschrift fur Rheumatologie

authors： van den Hoogen FH

更新日期：2006-07-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) results from loss of immunological tolerance. Regulatory T‑cells (Treg) are major gatekeepers of peripheral tolerance by suppression of autoreactive lymphocytes. Defects in Treg function are therefore possible pathogenetic mechanisms of SLE. Despite this fact published work about num...

journal_title：Zeitschrift fur Rheumatologie

authors： Ohl K,Tenbrock K

更新日期：2016-04-01 00:00:00

abstract：:In order to measure therapeutic effects or assess disease course, outcomes measurement parameters are commonly used in patients with rheumatoid arthritis. From the patient's perspective, possibly the most important outcome measurement parameter is quality of life (QoL). QoL may be defined in terms of "health status" a...

journal_title：Zeitschrift fur Rheumatologie

authors： Stamm T

更新日期：2010-05-01 00:00:00

abstract：:In rheumatologic diseases magnet resonance imaging (MRI) is capable of depicting early inflammatory changes which are frequently missed by other imaging modalities. New MRI protocols and hardware, primarily whole-body MRI and low-field extremity MRI facilitate the use of MRI in rheumatology patients. The increasing nu...

journal_title：Zeitschrift fur Rheumatologie

authors： Buchbender C,Schneider M,Ostendorf B

更新日期：2013-03-01 00:00:00