[The apoptosis marker enzyme poly-(ADP-ribose) polymerase (PARP) in systemic lupus erythematosus].

abstract：BACKGROUND:Taking part in physical education is an important element of social participation for children with chronic diseases. Nevertheless, children suffering from rheumatism mostly receive recommendations to stop sport activities either completely or partially, without underlying scientific guidelines. OBJECTIVE:T...

journal_title：Zeitschrift fur Rheumatologie

authors： Hartmann M,Merker J,Schrödl S,König M,Georgi M,Hinze C,Schwirtz A,Haas JP

更新日期：2018-10-01 00:00:00

abstract：:Methotrexate (MTX) is a safe and well-tolerated drug for the treatment of rheumatic diseases, even if the strictest safety standards are considered. Initial apprehension as to severe pulmonary or hepatic side-effects has not been confirmed. The risk of infection is not elevated compared with other disease-modifying an...

journal_title：Zeitschrift fur Rheumatologie

authors： Keysser G

更新日期：2011-02-01 00:00:00

abstract：:A few days after the SARS-CoV-2 infection was declared a pandemic, the German Society for Rheumatology (DGRh) compiled first recommendations for the care of patients with inflammatory rheumatic diseases (IRD). These first recommendations were based on an expert consensus and were largely non-evidence-based. Now that t...

journal_title：Zeitschrift fur Rheumatologie

authors： Schulze-Koops H,Iking-Konert C,Leipe J,Hoyer BF,Holle J,Moosig F,Aries P,Burmester G,Fiehn C,Krause A,Lorenz HM,Schneider M,Sewerin P,Voormann A,Wagner U,Krüger K,Specker C,Kommission Pharmakotherapie.,Vorstand der De

更新日期：2020-09-01 00:00:00

abstract：:A 74-year-old female patient with rheumatoid arthritis was diagnosed with Pneumocystis jiroveci pneumonia (PcP) following therapy with methotrexate and prednisone. Although bactrim treatment was initiated and PcP was not detected by a control bronchoalveolar lavage, the patient died. The precise cause of death remains...

journal_title：Zeitschrift fur Rheumatologie

authors： Bertisch B,Ruef C

更新日期：2006-02-01 00:00:00

abstract：:The German Rheuma-Liga as the largest patient organisation presents the different ways of informing patients. Patient- education-programs are presented, with a program focussing on social and psychological issues in particular. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Cattelaens K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:The relative efficacy and safety of tofacitinib and baricitinib were assessed in patients with rheumatoid arthritis (RA) with an inadequate response to disease-modifying anti-rheumatic drugs (DMARDs) or biologics. METHODS:We performed a Bayesian network meta-analysis to combine direct and indirect evidence ...

journal_title：Zeitschrift fur Rheumatologie

authors： Bae SC,Lee YH

更新日期：2019-08-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is associated with a shortened life expectancy. Most premature deaths are caused by cardiovascular (CV) events; therefore it is of importance to consider the increased CV risk when treating RA patients. Traditional CV risk factors cannot fully explain the increased risk but the common underst...

journal_title：Zeitschrift fur Rheumatologie

authors： Pieringer H,Hoppe UC

更新日期：2013-05-01 00:00:00

abstract：:The duration and severity of rheumatic diseases of the shoulder correlate with symptom frequency, structural changes and associated functional limitations. The multifactorial character of the underlying rheumatic disease requires a multimodal therapeutic concept including interaction of surgical and non-surgical disci...

journal_title：Zeitschrift fur Rheumatologie

authors： Heers G,Grifka J,Springorum HR,Craiovan B,Anders S

更新日期：2015-11-01 00:00:00

abstract：:This study documents prospectively the Knee Society knee- and function score of 28 patients with rheumatoid arthritis with 34 PFC unconstrained total knee arthroplasties from preoperative values on at yearly intervals. The average follow-up period was 3.4 years (range 2-5.5 y). At last follow-up over 80% of the knees ...

journal_title：Zeitschrift fur Rheumatologie

authors： König A,Janssen E,Scheidler M,Gohlke F

更新日期：1997-07-01 00:00:00

abstract：:From the about 400 virus species known to cause illness in man, only a small but growing list of representatives are able to induce arthritis. Although virus-associated arthritides are mostly of acute and short-living type, some patients develop long-lasting or even chronic joint inflammation. The viral or host factor...

journal_title：Zeitschrift fur Rheumatologie

authors： Saal JG

更新日期：1995-11-01 00:00:00

abstract：:We investigated the relationships between prolactin (PRL) levels and antibody occurrence in systemic lupus erythematosus (SLE). No significant association between PRL levels and the majority of the autoantibodies studied (anti-U1 RNP, anti-rRNP, anti-Sm, anti-dsDNA, anti-DNP, auto-LCA, anti-EACA) could be confirmed (P...

journal_title：Zeitschrift fur Rheumatologie

authors： Kozáková D,Rovenský J,Cebecauer L,Bosák V,Jahnová E,Vigas M

更新日期：2000-01-01 00:00:00

abstract：:The biochemical defect leading to alcaptonuria is well known. However, the pathogenesis of ochronotic arthropathy is poorly understood. The present ultrastructural study elucidated the localization of ochronotic pigment in the articular cartilage and evidence was found that suggests a pathway for cartilage destruction...

journal_title：Zeitschrift fur Rheumatologie

authors： Mohr W,Wessinghage D,Lenschow E

更新日期：1980-03-01 00:00:00

abstract：:Large data bases and the projects arising from them have led to a much improved understanding of systemic sclerosis over the last decade. Serology has developed further so that more autoantibodies are available for routine testing. Capillary microscopy has become standard and relevant progress has also been made in th...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Müller-Ladner U,Burkhardt H,Distler JH,Distler O,Graninger WB,Günther C,Hunzelmann N,Kiener H,Sticherling M,Sunderkötter C,Walker UA,Riemekasten G

更新日期：2015-03-01 00:00:00

abstract：:The aim of this review is to critically analyze the evidence of therapeutic ultrasound between 0.8 and 3 MHz for treating musculoskeletal diseases. Relevant randomized, controlled, clinical trials and systematic reviews published on this topic have been taken into consideration.There was evidence of effectiveness for ...

journal_title：Zeitschrift fur Rheumatologie

authors： Ebenbichler G

更新日期：2009-09-01 00:00:00

abstract：:Seronegative rheumatoid arthritis (RA) patients have increased proportions of OKT-4+ (helper) T cells and diminished proportions of OKT-8+ (suppressor/cytotoxic) T cells in the peripheral blood. This phenomenon corresponds to diminished inhibition of B cell activation by peripheral blood lymphocytes (PBL). Seropositiv...

journal_title：Zeitschrift fur Rheumatologie

authors： Lemm G,Warnatz H

更新日期：1984-05-01 00:00:00

abstract：OBJECTIVE:The aim in this study was to determine whether solute carrier family 22, member 4 (SLC22A4), and runt-related transcription factor 1 (RUNX1) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA) in populations of different ethnicities. METHODS:We conducted a literature search using th...

journal_title：Zeitschrift fur Rheumatologie

authors： Lee YH,Bae SC,Kim JH,Seo YH,Choi SJ,Ji JD,Song GG

更新日期：2015-05-01 00:00:00

abstract：:Inflammatory myopathies are as a rule rare diseases of skeletal muscle. In the majority of cases noninfective autoimmunological reactions are assumed. Only few diseases have an infectious origin. From a myopathological point of view, polymyositis must be selected from interstitial nodular myositis. The most important ...

journal_title：Zeitschrift fur Rheumatologie

authors： Pongratz D

更新日期：1986-07-01 00:00:00

abstract：:Patients with rheumatic diseases need a comprehensive and interdisciplinary treatment. In this context patient education takes the part to lead patients to a better self-management. The goals of patient education are the increase of knowledge and introspection, the positive influencing of attitudes and self-efficacy a...

journal_title：Zeitschrift fur Rheumatologie

authors： Ehlebracht-König I

更新日期：2003-01-01 00:00:00

abstract：:Twenty-three patients with rheumatoid arthritis and relevant anemia (hemoglobin < 11 g/dl) received recombinant erythropoietin (epo) in a therapy study; 90% were responders. A positive correlation of the total epo dose and the amelioration of parameters of red cell line and a negative correlation of the effect of epo ...

journal_title：Zeitschrift fur Rheumatologie

authors： Rave O,Wienands K

更新日期：1995-01-01 00:00:00

abstract：:Biomarkers form the basis for patient stratification and the development of individualized treatment strategies. As the understanding of the pathophysiological processes underlying rheumatic diseases increases, novel biomarkers will become available and established markers can be used more efficiently. Autoantibodies ...

journal_title：Zeitschrift fur Rheumatologie

authors： Scherer HU,Burmester GR,Häupl T

更新日期：2013-02-01 00:00:00

abstract：:In rheumatic diseases, radiation synovectomy is a reliable method. Meanwhile, radiation synovectomy is an outpatient therapy. In addition, combination with arthroscopic synovectomy is an increasing therapeutic modality. In comparison to the hitherto inpatient modality, a greater lymphatic emigration of the radionuclid...

journal_title：Zeitschrift fur Rheumatologie

authors： Klett R,Puille M,Matter HP,Steiner D,Stürz H,Bauer R

更新日期：1999-08-01 00:00:00

abstract：:The antidesoxyribonuclease B reaction shows in persons of all classes of age examined a similar distribution of titres as the antistreptolysin reaction. The anti DNase B titres however are mostly lower than the titres of the antistreptolysin reaction, except in the group of children, 6 to 17 years of age, suffering fr...

journal_title：Zeitschrift fur Rheumatologie

authors： Otto R,Richter M,Scholz E,Neumann G

更新日期：1981-01-01 00:00:00

abstract：:Rheumatology training is reorganized with the implementation of the revision of the training regulations for German physicians (MWBO) to become a specialist in internal medicine and rheumatology. This article focusses on novel aspects including far-reaching waiver of reference numbers, the professionally recommended t...

journal_title：Zeitschrift fur Rheumatologie

authors： Fleck M,Berliner MN,Krause A

更新日期：2020-11-30 00:00:00

abstract：:Personalized healthcare tries to predict the effectiveness and safety in individual therapeutic approaches by defining individual patient characteristics (biomarkers), while stratification uses diagnostic patterns for groups of patients for prediction of therapeutic response with less adverse reactions caused by the d...

journal_title：Zeitschrift fur Rheumatologie

authors： Behrens F,Köhm M

更新日期：2013-02-01 00:00:00

abstract：:We report on a 60 year old patient with peripheral neuropathy, neurogenic muscular atrophy, skin ulcers, arthritis and weakness. Detection of cryoglobulins in association with typical clinical symptoms, exclusion of hepatitis C and any other disease led to a rare diagnosis: essential cryoglobulinemic vasculitis. The c...

journal_title：Zeitschrift fur Rheumatologie

authors： Strunk J,Taborski U,Neeck G

更新日期：2002-12-01 00:00:00

abstract：:After approval of TNF and interleukin-1 inhibiting agents for treatment of refractory rheumathoid arthritis, new agents inhibiting interleukin-6 and costimulatory pathways are entering clinical phase I and II trials. Blockade of costimulation by using a CTLA4 immunoglobulin fusion protein (CTLA4Ig), which inhibits the...

journal_title：Zeitschrift fur Rheumatologie

authors： Perniok A,Rubbert-Roth A

更新日期：2003-10-01 00:00:00

abstract：:The sulfhydryl groups are chemically active parts of the protein molecule and participate in many important biochemical and metabolic processes. The present material comprised 132 patients with rheumatoid arthritis, 104 patients with other diseases and 44 controls. The patients with rheumatoid arthritis had decreased ...

journal_title：Zeitschrift fur Rheumatologie

authors： Haataja M,Kalliomäki JL

更新日期：1977-03-01 00:00:00

abstract：:The knee joint is often involved in rheumatoid arthritis. Despite ever-improving medical antirheumatic therapies, surgical treatment continues to play an important role in optimal multidisciplinary care. The aim of the present work is to process current orthopedic surgical therapy procedures on the knee joint accordin...

journal_title：Zeitschrift fur Rheumatologie

authors： Maderbacher G,Greimel F,Schaumburger J,Grifka J,Baier C

更新日期：2018-12-01 00:00:00

abstract：:Patients with various kinds of intestinal illnesses sometimes suffer not only abdominal symptoms, but also joint involvement, leading to a reduction in quality of life. Diseases leading to inflammatory joint involvement such as inflammatory bowel disease, Whipple's disease or surgical intestinal bypass, are classified...

journal_title：Zeitschrift fur Rheumatologie

authors： Ronneberger M

更新日期：2009-06-01 00:00:00

abstract：:The author describes the information gained from anamnesis which points to a psychogenetic cause of rheumatic complaints. These symptoms are part of the diagnostically important criteria which must be supplemented still further by means of a personal discussion with the patient. A great deal depends on the skill of th...

journal_title：Zeitschrift fur Rheumatologie

authors： Mathies H

更新日期：1993-07-01 00:00:00