[Enteropathic arthritis: water in the intestines, fire in the joints].

abstract：:A dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis was found in animal models of chronic inflammatory diseases, and the defect was located in more central portions of the HPA axis. This defect of neuroendocrine regulatory mechanisms contributes to the onset of the model disease. Since these first observati...

journal_title：Zeitschrift fur Rheumatologie

authors： Straub RH,Schölmerich J,Zietz B

更新日期：2000-01-01 00:00:00

abstract：:Cartilage destruction in arthritis and osteoarthritis is linked to aberrant cytokine and growth factor expression in the affected tissues. It becomes clear that the balance of protective and destructive cytokines is more important for the net destruction than the absolute levels of destructive mediators. IL-1 is a key...

journal_title：Zeitschrift fur Rheumatologie

authors： van den Berg WB

更新日期：1999-06-01 00:00:00

abstract：:The revised S2 guidelines for treatment of giant cell arteritis have recently been published. Glucocorticosteroids remain the standard first line treatment. For severe or relapsing courses of the disease, the IL‑6 antagonist tocilizumab, a potent antibody, is now available as a therapeutic option; however, how long th...

journal_title：Zeitschrift fur Rheumatologie

authors： Henes J

更新日期：2020-12-22 00:00:00

abstract：:Clinical pathways for three rheumatological indications have been successfully developed in the rheumatological departments of two hospitals. These diseases were selected because of the number of inpatients seen and/or the costs for diagnostics and therapy. Three quota-concepts, the coordination of treatment processes...

journal_title：Zeitschrift fur Rheumatologie

authors： Lakomek HJ,Hülsemann JL,Küttner T,Buscham K,Roeder N

更新日期：2007-05-01 00:00:00

abstract：:Fabry's disease is a hereditary lipid storage disease with deposition of ceramides in nearly all tissues. The lipid deposition in the skin and the synovial compartments causes an enlargement of the skin, the joint capsules and the tendon sheaths, which are recognizable by low KV radiography. The bones of the hand main...

journal_title：Zeitschrift fur Rheumatologie

authors： Fischer E

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Clinical observation suggests a frequent coincidence of back pain (BP) and fibromyalgia (FMA). Based on data from a population survey on back pain we studied the hypothesis of FMA being a frequent underlying condition of BP. We additionally studied the association of the severity of back pain and both chroni...

journal_title：Zeitschrift fur Rheumatologie

authors： Hüppe A,Brockow T,Raspe H

更新日期：2004-02-01 00:00:00

abstract：:Ocular manifestation of sarcoidosis occurs in up to 60% of patients with confirmed systemic sarcoidosis and represents one of the most common forms of noninfectious uveitis. In known pulmonary sarcoidosis, ocular involvement can occur in up to 80% of cases. Sarcoidosis can also present only in the eye, without a syste...

journal_title：Zeitschrift fur Rheumatologie

authors： Springer-Wanner C,Brauns T

更新日期：2017-06-01 00:00:00

abstract：:Interstitial nephritis is responsible for about 12 % of end-stage renal disease in Germany. It comprises an etiologically heterogenous group of inflammatory renal disorders which primarily affect the renal interstitium and tubuli. Drugs, predominantly antibiotics, nonsteroidal anti-inflammatory drugs and proton pump i...

journal_title：Zeitschrift fur Rheumatologie

authors： Korsten P,Müller GA

更新日期：2015-05-01 00:00:00

abstract：:A 74-year-old female patient with rheumatoid arthritis was diagnosed with Pneumocystis jiroveci pneumonia (PcP) following therapy with methotrexate and prednisone. Although bactrim treatment was initiated and PcP was not detected by a control bronchoalveolar lavage, the patient died. The precise cause of death remains...

journal_title：Zeitschrift fur Rheumatologie

authors： Bertisch B,Ruef C

更新日期：2006-02-01 00:00:00

abstract：:Osteoid osteomas are painful bone tumors that usually occur in childhood or adolescence. Despite the small size of the bony lesions osteoid osteomas can cause persistent pain. Pathogenesis has not been completely understood. Remission usually occurs within several months to years. Therefore surgical therapy is not ind...

journal_title：Zeitschrift fur Rheumatologie

authors： Hedrich CM,Fiebig B,Sallmann S,Bruck N,Thielemann F,Hahn G,Heubner G,Gahr M

更新日期：2008-03-01 00:00:00

abstract：:The photometric latex test (PLT) for the detection of rheumatoid factors (RF) has been correlated with the sensitized sheep cell test (SSC) and the latex slide test (LST). A total of 377 sera from patients with rheumatoid arthritis (RA) and 120 sera from control subjects were examined. When the PLT was carried out on ...

journal_title：Zeitschrift fur Rheumatologie

authors： Dezelić N,Zergollern V,Dezelić G,Dürrigl T,Jurak H,Vitaus M,Androić S

更新日期：1978-03-01 00:00:00

abstract：INTRODUCTION:Only insufficient data are available regarding the question whether treatment with immunosuppressants or biologicals is feasible and safe in patients with a history of malignancy. METHOD:Literature search via PubMed, EULAR abstracts and ACR abstracts from 2013 to 2015. RESULTS:The Société Francaise de Rh...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmalzing M,Strangfeld A,Tony HP

更新日期：2016-02-01 00:00:00

abstract：:Arthrosis deformans is a common disease worldwide with a high prevalence among all ethnic groups. All joints may be affected and genetic factors influence the onset of the disease. The main symptoms include pain and increasing immobility over the course of the illness. Treatment in early stages is conservative. In the...

journal_title：Zeitschrift fur Rheumatologie

authors： Rehart S,Lehnert H

更新日期：2008-07-01 00:00:00

abstract：AIM:To explore the circadian rhythm of serum interleukin (IL)-6 in collagen-induced arthritis (CIA) rats and compare the safety and effectiveness of methotrexate (MTX) administered traditionally and via chronotherapy. METHODS:CIA rat models were immunized with bovine type II collagen. Serum IL-6 levels in normal and C...

journal_title：Zeitschrift fur Rheumatologie

authors： Wang X,Yan X,Wang F,Ge F,Li Z

更新日期：2018-04-01 00:00:00

abstract：:The duration and severity of rheumatic diseases of the shoulder correlate with symptom frequency, structural changes and associated functional limitations. The multifactorial character of the underlying rheumatic disease requires a multimodal therapeutic concept including interaction of surgical and non-surgical disci...

journal_title：Zeitschrift fur Rheumatologie

authors： Heers G,Grifka J,Springorum HR,Craiovan B,Anders S

更新日期：2015-11-01 00:00:00

abstract：:Due to the relative increase of age-diabetes and to the different forms of rheumatic diseases, long-term medicament therapy and the question of possible interactions between oral antidiabetic drugs ( OAD ) and nonsteroidal anti-inflammatory drugs (NSAID) become more important. Unfortunately there exist studies on most...

journal_title：Zeitschrift fur Rheumatologie

authors： Knüsel O

更新日期：1984-03-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is associated with a shortened life expectancy. Most premature deaths are caused by cardiovascular (CV) events; therefore it is of importance to consider the increased CV risk when treating RA patients. Traditional CV risk factors cannot fully explain the increased risk but the common underst...

journal_title：Zeitschrift fur Rheumatologie

authors： Pieringer H,Hoppe UC

更新日期：2013-05-01 00:00:00

abstract：:Low back pain (LBP) in patients with rheumatoid arthritis (RA) has so far been of little concern in clinical investigations. The main focus of scientific publications on spinal problems in RA was the cervical spine. In a recent study, we could demonstrate that LBP in RA patients leads to a significantly higher degree ...

journal_title：Zeitschrift fur Rheumatologie

authors： Kothe R

更新日期：2017-12-01 00:00:00

abstract：:Systemic sclerosis (SSc, scleroderma) is a multisystem disease with a bad prognosis. No drugs have been shown to cure this disease. In view of its pathogenesis, in which immune responses are presumed to play an important role, immune suppressive therapies are widely applied in the treatment of SSc. Recent placebo-cont...

journal_title：Zeitschrift fur Rheumatologie

authors： van den Hoogen FH

更新日期：2006-07-01 00:00:00

abstract：:To study the hormonal perturbations in FMS patients we injected sixteen FMS patients and seventeen controls a cocktail of the hypothalamic releasing hormones: Corticotropin-releasing hormone (CRH), Thyrotropin-releasing hormone (TRH), Growth hormone-releasing hormone (GHRH), and Luteinizing hormone-releasing hormone (...

journal_title：Zeitschrift fur Rheumatologie

authors： Riedel W,Layka H,Neeck G

更新日期：1998-01-01 00:00:00

abstract：:In order to measure therapeutic effects or assess disease course, outcomes measurement parameters are commonly used in patients with rheumatoid arthritis. From the patient's perspective, possibly the most important outcome measurement parameter is quality of life (QoL). QoL may be defined in terms of "health status" a...

journal_title：Zeitschrift fur Rheumatologie

authors： Stamm T

更新日期：2010-05-01 00:00:00

abstract：UNLABELLED:Influence of anti-rheumatic drugs on human lymphocytes, especially T and B cell membranes, was studies with D-penicillamine, aurothiomalate, dexamethasone, cyclophosphamide, mitomycin C and aspirin. METHOD:Peripheral blood obtained from five healthy individuals and lymphocytes were separated by centrifugati...

journal_title：Zeitschrift fur Rheumatologie

authors： Yoshino S,Ishiyama I

更新日期：1977-01-01 00:00:00

abstract：:This review presents data on morbidity and mortality in patients with spondyloarthritis (SpA). Morbidity in patients with SpA is mainly determined by impairment of function and development of structural lesions. The course of illness in patients with ankylosing spondylitis (AS) is influenced by comorbidities, such as ...

journal_title：Zeitschrift fur Rheumatologie

authors： Kiltz U,Sieper J,Braun J

更新日期：2011-08-01 00:00:00

abstract：:Among the rheumatic diseases, systemic lupus erythematosus (SLE) reveals the highest frequency of central nervous symptoms. Psychiatric abnormalities are present in over 90% of the patients, if very mild cognitive impairment is included. The psychiatric syndromes listed by the American College of Rheumatologists encom...

journal_title：Zeitschrift fur Rheumatologie

authors： Haupt M

更新日期：2004-04-01 00:00:00

abstract：:The name of Sir Alfred Baring Garrod is linked with the first detection of uric acid in blood and its accumulation in sufferers from gout as well as the formulation of the term rheumatoid arthritis. The disease concept formulated by him initially (especially in Germany) caused confusion and much discussion but has now...

journal_title：Zeitschrift fur Rheumatologie

authors： Keitel W

更新日期：2009-12-01 00:00:00

abstract：:OM 8930, a bacterial product with immunostimulatory capacities, was studied for its efficacy in the long-term treatment of rheumatoid arthritis (RA). Ten (10) patients with active seropositive rheumatoid arthritis were treated intermittently for six months with the agent and were evaluated according to clinical, labor...

journal_title：Zeitschrift fur Rheumatologie

authors： Rosenthal M,Plattner S

更新日期：1981-09-01 00:00:00

abstract：:Osteoarthritis is the most common joint disease. In addition to known risk factors e.g. genetics, age and hormonal status it has been suggested that chronic-repetitive micro- and substantial (macro-) injury may play an important pathogenetic role. In a longitudinal case-study we examined Judo-players for clinical and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Strasser P,Hauser M,Häuselmann HJ,Michel BA,Frei A,Stucki G

更新日期：1997-12-01 00:00:00

abstract：:Various rheumatic symptoms can occur in association with malignancies and are termed the so-called paraneoplastic arthropathy. The clinical picture is often similar to primary inflammatory rheumatic diseases. At present there exist no epidemiological data on this disease entity. The case of a patient with tibial pain ...

journal_title：Zeitschrift fur Rheumatologie

authors： Lange U,Bachmann G,Müller-Ladner U

更新日期：2011-06-01 00:00:00

abstract：:Activated monocytes/macrophages secrete monokines, regulatory proteins which are capable of initiating and maintaining immune processes as well as having an effect on other non immunocompetent cells. In rheumatoid arthritis the monokine Interleukin-1 (IL-1) was detected in the synovial fluid. IL-1 activates immunocomp...

journal_title：Zeitschrift fur Rheumatologie

authors： Hermann E,Müller W

更新日期：1985-09-01 00:00:00

abstract：:After approval of TNF and interleukin-1 inhibiting agents for treatment of refractory rheumathoid arthritis, new agents inhibiting interleukin-6 and costimulatory pathways are entering clinical phase I and II trials. Blockade of costimulation by using a CTLA4 immunoglobulin fusion protein (CTLA4Ig), which inhibits the...

journal_title：Zeitschrift fur Rheumatologie

authors： Perniok A,Rubbert-Roth A

更新日期：2003-10-01 00:00:00