[Inflammatory muscle diseases].

abstract：:A 28-year-old female patient had load-dependent pain of the left knee. MRI showed an osteochondral defect of the medial condyle based on extensive osteonecrosis of the femoral and tibial bone. An association with a prior steroid treatment after cervical injury is most likely. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Steinhagen J,Rüther W

更新日期：2004-06-01 00:00:00

abstract：:Recent Deutsche Gesellschaft für Rheumatologie (DGRh, German Society of Rheumatology) guidelines emphasized the significance of coordinated multidisciplinary care and rehabilitation of patients with inflammatory rheumatic diseases. Nationwide data from the German pension insurance funds showed that inpatient rehabilit...

journal_title：Zeitschrift fur Rheumatologie

authors： Mau W,Beyer W,Ehlebracht-König I,Engel JM,Genth E,Jäckel WH,Lange U,Thiele K

更新日期：2014-03-01 00:00:00

abstract：:Methotrexate (MTX) is a safe and well-tolerated drug for the treatment of rheumatic diseases, even if the strictest safety standards are considered. Initial apprehension as to severe pulmonary or hepatic side-effects has not been confirmed. The risk of infection is not elevated compared with other disease-modifying an...

journal_title：Zeitschrift fur Rheumatologie

authors： Keysser G

更新日期：2011-02-01 00:00:00

abstract：:Up to now stratified therapy concepts have not played an important role in the treatment of patients with rheumatoid arthritis; however, a high heterogeneity regarding the effectiveness of therapies and occurrence of side effects in patients with the same indications provokes research efforts aiming at identifying and...

journal_title：Zeitschrift fur Rheumatologie

authors： Frank M,Mittendorf T

更新日期：2013-02-01 00:00:00

abstract：:The effect of recombinant interleukin-2 (IL-2) on proliferative and cytotoxic response of peripheral blood mononuclear cells (PBMC) was investigated in a group of 21 patients with systemic lupus erythematosus (SLE). There was a significant decrease in thymidine uptake of peripheral blood mononuclear cells when compare...

journal_title：Zeitschrift fur Rheumatologie

authors： Jira M,Strejcek J,Zavadil Z,Antosova E,Rejholec V

更新日期：1990-01-01 00:00:00

abstract：:In recent years German authorities established a global budget for health care expenditures solely based on macroeconomic aspects. In the last year there have been attempts to define differentiated budgets for chronic diseases. These plans are mainly defined by quality aspects on the process level (creating networks) ...

journal_title：Zeitschrift fur Rheumatologie

authors： Karger T

更新日期：1998-12-01 00:00:00

abstract：:The effect of D-penicillamine, given for 14 days in doses of 100 mg/kg and 225 mg/kg, upon the collagen metabolism of skin and bone tissues was studied in rats. The smaller dosage of D-penicillamine did not effect the collagen synthesis in skin or bone. When the higher dosage was used, however, an increase of collagen...

journal_title：Zeitschrift fur Rheumatologie

authors： Trnavská Z,Trnavský K

更新日期：1977-05-01 00:00:00

abstract：:Polyarthralgias are widely common complaints. In earlier stages it might be difficult to state the right diagnosis. Differential diagnosis is absolutely necessary for starting in time with the right treatment. Out of a great clinical material the following diseases causing mono-, oligo- or polyarthralgia were discusse...

journal_title：Zeitschrift fur Rheumatologie

authors： Singer F

更新日期：1982-01-01 00:00:00

abstract：:In the last years some important therapies were introduced in the treatment of rheumatoid arthritis (RA), which represent a significant clinical advance. This concerns the introduction of TNF blockade with etanercept and inflixmab, the combination of DMARDs, leflunomide and the COX-2-specific inhibitors. In the year 2...

journal_title：Zeitschrift fur Rheumatologie

authors： Edelmann E

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease affecting a broad range of different organ systems and, hence, presenting with multiple symptomatic domains, which considerably reduces the quality of life of patients. Within the last decade the prognosis of the disease has been...

journal_title：Zeitschrift fur Rheumatologie

authors： Schneider M,Haupt M

更新日期：2015-09-01 00:00:00

abstract：:Assessment of disease consequences (outcome) requires reliable, valid, and sensitive instruments. Psychometrically sound generic health-status instruments such as the SF-36 have been validated for many languages and are available in German. Instead, most disease specific instruments have been developed in English and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Stucki G,Stucki S,Sangha O

更新日期：1997-10-01 00:00:00

abstract：:In general, the risk of serious infections increases with age, mainly explained by immunosenescence and accumulation of comorbidities. Those patients with rheumatoid arthritis who are of advanced age and require treatment with immunosuppressive agents are at particular risk to develop an infectious disease. Actual req...

journal_title：Zeitschrift fur Rheumatologie

authors： Kneitz C,Strangfeld A,Krüger K

更新日期：2014-04-01 00:00:00

abstract：:Evaluation of the sensitivity and value of magnetic resonance imaging (MRI) findings and miniarthroscopic investigations (mini-/needle-arthroscopy = MA) of metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis (RA). 30 patients with RA (21 female, 9 male), disease duration 2 months to 22 years and mea...

journal_title：Zeitschrift fur Rheumatologie

authors： Peters R,Ostendorf B,Scherer A,Becker A,Dann P,Merk H,Mödder U,Schneider M

更新日期：2002-04-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：:Our aim is to present a new method to examine spinal mobility and spine shape excluding torsional scoliosis. In comparison to measuring devices of the spine used so far, this noninvasive and easy to use method documents altered patterns of intervertebral mobility of the lumbar and thoracic spine. This may lead to a br...

journal_title：Zeitschrift fur Rheumatologie

authors： Hauns B,Ovenhausen K,Hase P,Lorenzen W,Mennet P,Stratz T,Müller W

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:The aim in this study was to determine whether solute carrier family 22, member 4 (SLC22A4), and runt-related transcription factor 1 (RUNX1) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA) in populations of different ethnicities. METHODS:We conducted a literature search using th...

journal_title：Zeitschrift fur Rheumatologie

authors： Lee YH,Bae SC,Kim JH,Seo YH,Choi SJ,Ji JD,Song GG

更新日期：2015-05-01 00:00:00

abstract：:Monocytes from patients with definite or classical rheumatoid arthritis show a significantly higher release of O2-radicals in the chemiluminescence assay (2925 X 10(3) cpm) than those of healthy volunteers (267 X 10(3) cpm) (p = 0.01). This difference does not appear in a similar test with granulocytes, which in both ...

journal_title：Zeitschrift fur Rheumatologie

authors： Meske S,Maly FE,Estefan M,Müller W

更新日期：1985-01-01 00:00:00

abstract：:Big data analysis raises the expectation that computerized algorithms may extract new knowledge from otherwise unmanageable vast data sets. What are the algorithms behind the big data discussion? In principle, high throughput technologies in molecular research already introduced big data and the development and applic...

journal_title：Zeitschrift fur Rheumatologie

authors： Bonin-Andresen M,Smiljanovic B,Stuhlmüller B,Sörensen T,Grützkau A,Häupl T

更新日期：2018-04-01 00:00:00

abstract：:The revised S2 guidelines for treatment of giant cell arteritis have recently been published. Glucocorticosteroids remain the standard first line treatment. For severe or relapsing courses of the disease, the IL‑6 antagonist tocilizumab, a potent antibody, is now available as a therapeutic option; however, how long th...

journal_title：Zeitschrift fur Rheumatologie

authors： Henes J

更新日期：2020-12-22 00:00:00

abstract：:Osteoid osteomas are painful bone tumors that usually occur in childhood or adolescence. Despite the small size of the bony lesions osteoid osteomas can cause persistent pain. Pathogenesis has not been completely understood. Remission usually occurs within several months to years. Therefore surgical therapy is not ind...

journal_title：Zeitschrift fur Rheumatologie

authors： Hedrich CM,Fiebig B,Sallmann S,Bruck N,Thielemann F,Hahn G,Heubner G,Gahr M

更新日期：2008-03-01 00:00:00

abstract：:Patient education is a medical intervention for patients with chronic diseases to increase knowledge of their disease, self-efficacy, self-management and consumer behaviour. The goal is to improve their disease outcome, social participation and quality of life. This article reviews concepts, modalities and knowledge o...

journal_title：Zeitschrift fur Rheumatologie

authors： Genth E

更新日期：2008-05-01 00:00:00

abstract：:We report on a 60 year old patient with peripheral neuropathy, neurogenic muscular atrophy, skin ulcers, arthritis and weakness. Detection of cryoglobulins in association with typical clinical symptoms, exclusion of hepatitis C and any other disease led to a rare diagnosis: essential cryoglobulinemic vasculitis. The c...

journal_title：Zeitschrift fur Rheumatologie

authors： Strunk J,Taborski U,Neeck G

更新日期：2002-12-01 00:00:00

abstract：:The improved options for effective treatment of osteoporosis and the shift to treatment strategies based on each patient's absolute fracture risk raise new questions in daily clinical care. Which patient should have what osteoprotective therapy and when and for how long? What techniques can be used to assess the indiv...

journal_title：Zeitschrift fur Rheumatologie

authors： Demary W

更新日期：2006-09-01 00:00:00

abstract：:Fiftythree patients with progressive systemic sclerosis were studied. Four of them (3 males) had the diffuse form of the disease. The skin manifestation of this clinical picture is characterized by diffuse progression of the cutaneous sclerosis over almost the whole body surface, except for the hands where it eventual...

journal_title：Zeitschrift fur Rheumatologie

authors： Giordano M,Ara M,Capelli L,Tirri G,Vatti M

更新日期：1976-07-01 00:00:00

abstract：:278 patients with ankylosing spondylitis have been studied in order to find a basis for prognosis by setting a mobility function index of the vertebral column. This index does not depend on manifestation age or on the blood sedimentation rate. It increases with progression of x-ray findings. A coincidence of impaired ...

journal_title：Zeitschrift fur Rheumatologie

authors： Schöffel J,Pohl W

更新日期：1975-11-01 00:00:00

abstract：:Intra-articular injection of corticosteroids is a powerful anti-inflammatory treatment with relatively few side effects. To date no prospective RCT exists on its use in children with oligoarthritis type I. Thus, in January 2000 the Arbeitsgemeinschaft started a multicenter RCT to compare in children with this diagnosi...

journal_title：Zeitschrift fur Rheumatologie

authors： Forster J

更新日期：2000-04-01 00:00:00

abstract：:Rheumatic diseases are among the most common chronic inflammatory disorders. Besides severe pain and progressive destruction of the joints, rheumatoid arthritis (RA), spondyloarthritides (SpA) and psoriatic arthritis (PsA) impair working ability, reduce quality of life and if treated insufficiently may enhance mortali...

journal_title：Zeitschrift fur Rheumatologie

authors： Häupl T,Skapenko A,Hoppe B,Skriner K,Burkhardt H,Poddubnyy D,Ohrndorf S,Sewerin P,Mansmann U,Stuhlmüller B,Schulze-Koops H,Burmester GR

更新日期：2018-05-01 00:00:00

abstract：:Cell-based therapeutical approaches are already in clinical use and are attracting growing interest for the treatment of joint defects. Mesenchymal stem and precursor cells (MSC) cover a wide range of properties that are useful for the regeneration process of bone and cartilage defects. The following article is an ove...

journal_title：Zeitschrift fur Rheumatologie

authors： Dehne T,Tschirschmann M,Lauster R,Sittinger M

更新日期：2009-05-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a mainstay in musculoskeletal imaging. The term"bone marrow edema" is frequently used for describing the radiological findings, especially with respect to rheumatic diseases. The referring physician should be aware that this term has a purely descriptive character and the pathophysi...

journal_title：Zeitschrift fur Rheumatologie

authors： Hamer OW,Kriegsmann J

更新日期：2012-01-01 00:00:00

abstract：:Patients with rheumatic diseases need a comprehensive and interdisciplinary treatment. In this context patient education takes the part to lead patients to a better self-management. The goals of patient education are the increase of knowledge and introspection, the positive influencing of attitudes and self-efficacy a...

journal_title：Zeitschrift fur Rheumatologie

authors： Ehlebracht-König I

更新日期：2003-01-01 00:00:00