[Chronic widespread pain and tender points in low back pain: a population-based study].

abstract：:Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...

journal_title：Zeitschrift fur Rheumatologie

authors： Valesová M,Trnavský K

更新日期：1990-07-01 00:00:00

abstract：:In order to measure therapeutic effects or assess disease course, outcomes measurement parameters are commonly used in patients with rheumatoid arthritis. From the patient's perspective, possibly the most important outcome measurement parameter is quality of life (QoL). QoL may be defined in terms of "health status" a...

journal_title：Zeitschrift fur Rheumatologie

authors： Stamm T

更新日期：2010-05-01 00:00:00

abstract：:Health policy in Germany has in recent years given priority to the self-administration of physicians, sickness funds, and hospital associations. Hence, legal regulations on quality assurance have focused on defining responsibilities and areas of primary importance, while precise processes are being defined by the self...

journal_title：Zeitschrift fur Rheumatologie

authors： Luithlen E,Aufderheide E

更新日期：1998-10-01 00:00:00

abstract：:Because it is a systemic disorder, rheumatoid arthritis (RA) is known to predispose affected individuals to other organ manifestations as well as arthritic problems. The serious complications include pericarditis, pulmonary and cutaneous nodules, episcleritis, and rheumatoid vasculitis. Of late, a significantly increa...

journal_title：Zeitschrift fur Rheumatologie

authors： Whelan P

更新日期：2006-10-01 00:00:00

abstract：:Reactive arthritis is an inflammatory joint disease induced by a preceding, sometimes asymptomatic bacterial infection outside the joints. With an estimated prevalence of 40/100,000 inhabitants, the disease primarily affects adults between the ages of 20 and 40 years. The clinical presentation is typically characteriz...

journal_title：Zeitschrift fur Rheumatologie

authors： Brzank M,Wollenhaupt J

更新日期：2013-12-01 00:00:00

abstract：:Low back pain (LBP) in patients with rheumatoid arthritis (RA) has so far been of little concern in clinical investigations. The main focus of scientific publications on spinal problems in RA was the cervical spine. In a recent study, we could demonstrate that LBP in RA patients leads to a significantly higher degree ...

journal_title：Zeitschrift fur Rheumatologie

authors： Kothe R

更新日期：2017-12-01 00:00:00

abstract：:A dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis was found in animal models of chronic inflammatory diseases, and the defect was located in more central portions of the HPA axis. This defect of neuroendocrine regulatory mechanisms contributes to the onset of the model disease. Since these first observati...

journal_title：Zeitschrift fur Rheumatologie

authors： Straub RH,Schölmerich J,Zietz B

更新日期：2000-01-01 00:00:00

abstract：:Monocytes from patients with definite or classical rheumatoid arthritis show a significantly higher release of O2-radicals in the chemiluminescence assay (2925 X 10(3) cpm) than those of healthy volunteers (267 X 10(3) cpm) (p = 0.01). This difference does not appear in a similar test with granulocytes, which in both ...

journal_title：Zeitschrift fur Rheumatologie

authors： Meske S,Maly FE,Estefan M,Müller W

更新日期：1985-01-01 00:00:00

abstract：UNLABELLED:The regulatory region of the corticotropin releasing hormone (CRH) is highly conserved and plays a crucial role in the response of the organism to stress. Release of CRH initiates a cascade of events leading to the release of cortisone and the regulation of inflammatory and immune events. OBJECTIVE:Since it...

journal_title：Zeitschrift fur Rheumatologie

authors： Baerwald CG,Mok CC,Tickly M,Lau CS,Wordsworth BP,Ollier B,Panayi GS,Lanchbury JS

更新日期：2000-02-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is mainly characterized by synovial hyperplasia, pathological immune phenomena and progressive destruction of the affected joints. Various cell types are involved in the pathogenesis of RA including T cells, antigen presenting cells, and endothelial ce...

journal_title：Zeitschrift fur Rheumatologie

authors： Seemayer CA,Distler O,Kuchen S,Müller-Ladner U,Michel BA,Neidhart M,Gay RE,Gay S

更新日期：2001-10-01 00:00:00

abstract：:Musculoskeletal ultrasonography (US) is an established and validated imaging technique in rheumatology. Ultrasonography is able to directly visualize soft tissue pathologies such as synovial tissue changes. Pathological findings in superficial cartilage, bone lesions and synovial tissue changes in the context of rheum...

journal_title：Zeitschrift fur Rheumatologie

authors： Tamborrini G,Backhaus M,Schmidt W,Ziswiler HR

更新日期：2010-12-01 00:00:00

abstract：:The assessment of off-label medications is one of the most common reasons for assessment of drugs for individual patients in the German medical services. Tension is not uncommon because of great expectations of patients and doctors on the one hand and the requirements of the law on the other. They often do not match. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grell L,Rieger M

更新日期：2012-02-01 00:00:00

abstract：:The immune system is regulated by a variety of mechanisms that prevent overwhelming immune responses and a break in tolerance. There have been indications for some time that populations of B cells are also a part of this network and able to exert regulatory functions. Here we summarize current knowledge on this previo...

journal_title：Zeitschrift fur Rheumatologie

authors： Tretter T,Lorenz HM

更新日期：2010-11-01 00:00:00

abstract：:The modified significance of radiological criterion in the new ACR/EULAR classification criteria for rheumatoid arthritis is based on the fact that the bone erosion seen using conventional radiology is the result of an already longstanding inflammatory process.In contrast, new imaging modalities such as magnetic reson...

journal_title：Zeitschrift fur Rheumatologie

authors： Strunk J

更新日期：2011-04-01 00:00:00

abstract：:An appropriate treatment of elderly rheumatic patients implements comprehensive diagnostics and exclusion diagnostics of e.g. coronary heart disease, osteoporosis, renal failure, diabetes mellitus type 2 and thyroid gland dysfunction. Furthermore, the complex disease situation might require the integration of other fa...

journal_title：Zeitschrift fur Rheumatologie

authors： Lakomek HJ,Brabant T,Lakomek M,Lüttje D

更新日期：2013-08-01 00:00:00

abstract：:Ocular manifestation of sarcoidosis occurs in up to 60% of patients with confirmed systemic sarcoidosis and represents one of the most common forms of noninfectious uveitis. In known pulmonary sarcoidosis, ocular involvement can occur in up to 80% of cases. Sarcoidosis can also present only in the eye, without a syste...

journal_title：Zeitschrift fur Rheumatologie

authors： Springer-Wanner C,Brauns T

更新日期：2017-06-01 00:00:00

abstract：:Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by, among other things, spinal and extraspinal manifestations. Two studies on the prevalence and clinical significance of hyperostotic spurs and ectopic ossifications in the pelvic area are presented. Spinal DISH seems to be a risk factor for the develop...

journal_title：Zeitschrift fur Rheumatologie

authors： Fahrer H,Koch P,Barandun R,Gerber NJ

更新日期：1988-07-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a mainstay in musculoskeletal imaging. The term"bone marrow edema" is frequently used for describing the radiological findings, especially with respect to rheumatic diseases. The referring physician should be aware that this term has a purely descriptive character and the pathophysi...

journal_title：Zeitschrift fur Rheumatologie

authors： Hamer OW,Kriegsmann J

更新日期：2012-01-01 00:00:00

abstract：:Tocilizumab, a monoclonal humanized antibody against IL-6, was licensed in January 2009 in combination with Methotrexate for the treatment of adult patients with moderately to severely active rheumatoid arthritis and inadequate response to one or more DMARDs or TNF antagonists. Tocilizumab is given once every 4 weeks ...

journal_title：Zeitschrift fur Rheumatologie

authors： Roll P,Rubbert-Roth A,Tony HP

更新日期：2010-09-01 00:00:00

abstract：:Up to now stratified therapy concepts have not played an important role in the treatment of patients with rheumatoid arthritis; however, a high heterogeneity regarding the effectiveness of therapies and occurrence of side effects in patients with the same indications provokes research efforts aiming at identifying and...

journal_title：Zeitschrift fur Rheumatologie

authors： Frank M,Mittendorf T

更新日期：2013-02-01 00:00:00

abstract：:This article gives a comprehensive overview of diffuse interstitial lung diseases especially those associated with connective tissue diseases. Interstitial lung diseases (ILD) represent a heterogeneous group of diseases of very different and partially unknown etiologies. Therefore, an exact classification of the ILD i...

journal_title：Zeitschrift fur Rheumatologie

authors： Koller HK,Burghuber OC

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To assess the relative efficacy and safety of apremilast, secukinumab, and ustekinumab at different doses in patients with active psoriatic arthritis (PsA). METHOD:A Bayesian network meta-analysis was conducted, which included randomized controlled trials (RCTs) that examined the efficacy and safety of aprem...

journal_title：Zeitschrift fur Rheumatologie

authors： Song GG,Lee YH

更新日期：2018-09-01 00:00:00

abstract：:T-Large Granular Lymphocyte (T-LGL) leukaemia is a rare clonal disease characterized by neutropenia and/or anaemia. Because of its strong association with rheumatoid arthritis (RA), T-LGL leukaemia is an important differential diagnosis to Felty's syndrome. This differentiation might be especially difficult since, in ...

journal_title：Zeitschrift fur Rheumatologie

authors： Moosig F,Schoch R,Kneba M

更新日期：2006-09-01 00:00:00

abstract：:Large data bases and the projects arising from them have led to a much improved understanding of systemic sclerosis over the last decade. Serology has developed further so that more autoantibodies are available for routine testing. Capillary microscopy has become standard and relevant progress has also been made in th...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Müller-Ladner U,Burkhardt H,Distler JH,Distler O,Graninger WB,Günther C,Hunzelmann N,Kiener H,Sticherling M,Sunderkötter C,Walker UA,Riemekasten G

更新日期：2015-03-01 00:00:00

abstract：:In recent years, new findings in immunology have been successfully converted to therapeutic principles, in particular for rheumatoid arthritis (RA) and spondylarthritides. The introduction of cytokine blockers in RA using tumor necrosis factor (TNF)-alpha and interleukin (IL)-1 inhibitors presented the first original ...

journal_title：Zeitschrift fur Rheumatologie

authors： Mei H,Dörner T

更新日期：2009-07-01 00:00:00

abstract：:The pressure load is critical for vascular wall alteration. Systolic blood pressure was measured by Doppler sonography in the finger and arm arteries of 24 patients with rheumatoid arthritis and compared to a control group (n = 22) of nearly the same age. The transmitter frequency of the ultrasound probe was 9.6 MHz. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Beste KW

更新日期：1985-05-01 00:00:00

abstract：:Over the last ten years various biologics have been introduced in the therapy of rheumatic diseases. The most successful approach so far has been the inhibition of TNF alpha, which is able to suppress systemic inflammation in an unprecedented manner. However, the early observation of newly developed antinuclear antibo...

journal_title：Zeitschrift fur Rheumatologie

authors： Manger K,Manger B

更新日期：2003-06-01 00:00:00

abstract：:Behçet's disease (BD) is a recurrent, multisystemic, inflammatory blood vessel disorder that can result in mouth, genital, and skin ulcers; arthritis; and eye and intestinal inflammation. We describe a 21-year-old Korean female patient with intestinal BD refractory to conventional medical treatment and biologic drugs....

journal_title：Zeitschrift fur Rheumatologie

authors： Kim HJ,Kim KT,Lee SG,Kim Y

更新日期：2020-09-01 00:00:00

abstract：:Eight patients with SLE were found on clinical and roentgenological grounds or by respiratory function tests to have evidence of lung involvement. Great discrepancies were noted between clinical findings and the results of the respiratory function tests on the one hand and lacking or discrete radiological changes on t...

journal_title：Zeitschrift fur Rheumatologie

authors： Görlitz N,Berzon R,Rössner B,Wessel G,Jäckel R

更新日期：1976-03-01 00:00:00

abstract：:The nephrotoxicity of methotrexate (MTX) is a phenomenon which is observed in high-dose therapy for treatment of malignant diseases. Even low-dose MTX therapy for treatment of rheumatic diseases is claimed to cause impairment in renal function. The necessity to adapt the dosage of MTX therapy for renal function disord...

journal_title：Zeitschrift fur Rheumatologie

authors： Fiehn C

更新日期：2011-12-01 00:00:00