Abstract:
:Monocytes from patients with definite or classical rheumatoid arthritis show a significantly higher release of O2-radicals in the chemiluminescence assay (2925 X 10(3) cpm) than those of healthy volunteers (267 X 10(3) cpm) (p = 0.01). This difference does not appear in a similar test with granulocytes, which in both groups tested show a mean chemiluminescence of 2739 X 10(3) and 2547 X 10(3) cpm. The chemiluminescence of monocytes is clearly time-course dependent: in the morning we saw the least response, at noon the highest. Following our results, corticosteroids lower chemiluminescence significantly (p = 0.05), while non steroidal antirheumatic drugs and long-term therapy with gold compounds, etc., do not affect chemiluminescence.
journal_name
Z Rheumatoljournal_title
Zeitschrift fur Rheumatologieauthors
Meske S,Maly FE,Estefan M,Müller Wsubject
Has Abstractpub_date
1985-01-01 00:00:00pages
41-5issue
1eissn
0340-1855issn
1435-1250journal_volume
44pub_type
杂志文章abstract::Aortic aneurysm and dissection are rare complications of systemic lupus erythematosus (SLE). The incidence, etiology, risk factors, and outcomes of this entity were largely unknown.The study materials were based on the publications of aortic aneurysm or dissection due to SLE published between 2000 and 2017.A total of ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-018-0555-x
更新日期:2019-04-01 00:00:00
abstract::Osteoarthritis is the most common joint disease. In addition to known risk factors e.g. genetics, age and hormonal status it has been suggested that chronic-repetitive micro- and substantial (macro-) injury may play an important pathogenetic role. In a longitudinal case-study we examined Judo-players for clinical and ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s003930050048
更新日期:1997-12-01 00:00:00
abstract::Health services research in rheumatology investigates the healthcare needs, the quality of care and trends in healthcare for patients with musculoskeletal disorders. Using rheumatoid arthritis (RA) as an example, key results of health services research during the last 25 years are summarized. There are currently appro...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-013-1258-y
更新日期:2014-03-01 00:00:00
abstract::The aim of this review is to critically analyze the evidence of therapeutic ultrasound between 0.8 and 3 MHz for treating musculoskeletal diseases. Relevant randomized, controlled, clinical trials and systematic reviews published on this topic have been taken into consideration.There was evidence of effectiveness for ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-009-0457-z
更新日期:2009-09-01 00:00:00
abstract::Among all laboratory parameters used today in the assessment of activity and progression of rheumatoid arthritis erythrocyte sedimentation rate (ESR) can only be recommended reservedly. ESR is influenced by anemia, reduction of plasma fibrinogen, dysproteinemia and by the concentration of acute phase proteins. Quantif...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Systemic sclerosis (SSc) is characterized by heterogeneous clinical symptoms. Peripheral skin fibrosis can be a common symptom. Nevertheless, a variety of diseases with different etiologies are associated with a thickening of the skin and make the initial diagnosis of systemic sclerosis more difficult. OBJE...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-018-0538-y
更新日期:2019-02-01 00:00:00
abstract::Heavy physical work load is a known determinant of osteoarthritis of the hip, which may account for the high risk observed among farmers. On the other hand, the data on influence of heavy manual work in the pathogenesis of hand osteoarthritis are still controversial. We examined 25 retired farm laborers who strenuousl...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s003930050193
更新日期:1999-12-01 00:00:00
abstract::Large data bases and the projects arising from them have led to a much improved understanding of systemic sclerosis over the last decade. Serology has developed further so that more autoantibodies are available for routine testing. Capillary microscopy has become standard and relevant progress has also been made in th...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-014-1550-5
更新日期:2015-03-01 00:00:00
abstract::Recent Deutsche Gesellschaft für Rheumatologie (DGRh, German Society of Rheumatology) guidelines emphasized the significance of coordinated multidisciplinary care and rehabilitation of patients with inflammatory rheumatic diseases. Nationwide data from the German pension insurance funds showed that inpatient rehabilit...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-013-1259-x
更新日期:2014-03-01 00:00:00
abstract::After clinical and radiological examination, the elbows of 74 patients with rheumatoid arthritis were examined by ultrasound. Clinical examination gives a good impression of the inflammatory changes of the elbow joint. Sonography was very useful in detecting synovitis and joint effusion and their distribution in the d...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract::Rheumatic diseases are among the most common chronic inflammatory disorders. Besides severe pain and progressive destruction of the joints, rheumatoid arthritis (RA), spondyloarthritides (SpA) and psoriatic arthritis (PsA) impair working ability, reduce quality of life and if treated insufficiently may enhance mortali...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-018-0458-x
更新日期:2018-05-01 00:00:00
abstract::Rheumatology training is reorganized with the implementation of the revision of the training regulations for German physicians (MWBO) to become a specialist in internal medicine and rheumatology. This article focusses on novel aspects including far-reaching waiver of reference numbers, the professionally recommended t...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-020-00930-z
更新日期:2020-11-30 00:00:00
abstract:AIM:The present study should elucidate the efficacy, patient acceptability, and side effect profiles of Oxaprozin and Diclofenac retard when given to patients with active primary osteoarthrosis. METHODS:80 outpatients with active primary osteoarthrosis with a radiological grade of II or III in the hip or knee joint (m...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s003930050068
更新日期:1998-04-01 00:00:00
abstract::In rheumatologic diseases magnet resonance imaging (MRI) is capable of depicting early inflammatory changes which are frequently missed by other imaging modalities. New MRI protocols and hardware, primarily whole-body MRI and low-field extremity MRI facilitate the use of MRI in rheumatology patients. The increasing nu...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-012-1068-7
更新日期:2013-03-01 00:00:00
abstract::Since 1978 a 63-year-old woman with rheumatoid arthritis received D-penicillamine (D-PA) in a daily dose of 250-500 mg (mean 300 mg/d). In 1982 the patient complained of diplopia for several days, the ophthalmological and neurological examinations three days later were normal. In July 1983 she developed a myasthenic s...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract::The evidence-based recommendations on the management of ankylosing spondylitis (AS) have enjoyed a high level of acceptance and circulation in Germany, as well as in other European countries. To make patient participation in the decision-making process regarding their disease easier, as well as to strengthen the physi...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-009-0428-4
更新日期:2010-03-01 00:00:00
abstract::The nephrotoxicity of methotrexate (MTX) is a phenomenon which is observed in high-dose therapy for treatment of malignant diseases. Even low-dose MTX therapy for treatment of rheumatic diseases is claimed to cause impairment in renal function. The necessity to adapt the dosage of MTX therapy for renal function disord...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 评论,杂志文章
doi:10.1007/s00393-011-0909-0
更新日期:2011-12-01 00:00:00
abstract::We report on a 60 year old patient with peripheral neuropathy, neurogenic muscular atrophy, skin ulcers, arthritis and weakness. Detection of cryoglobulins in association with typical clinical symptoms, exclusion of hepatitis C and any other disease led to a rare diagnosis: essential cryoglobulinemic vasculitis. The c...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-002-0389-3
更新日期:2002-12-01 00:00:00
abstract::Due to their anti-inflammatory effects and their capacity to affect the synthesis of most cytokines and the Th1/Th2 balance, endogenous glucocorticoids contribute to control the basal operation of immune cells. Immune processes result in the production of cytokines, such as IL-1, IL-2, IL-6, IL-11, IL-12, TNF-alpha, a...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s003930070014
更新日期:2000-01-01 00:00:00
abstract::Still's disease covers a range of disorders from systemic juvenile idiopathic arthritis (SJIA) up to adult onset Still's disease (AOSD). The overlapping clinical features suggest that SJIA and AOSD are different manifestations of a phenotypic continuum in different age stages. Still's disease is clinically characteriz...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-020-00779-2
更新日期:2020-09-01 00:00:00
abstract::The present study examined relations between irrational attitudes and pain experience in patients with rheumatoid arthritis (RA). 128 patients with definite RA from a rheumatic treatment center were studied by administration of the Irrational Attitudes Questionnaire (15) and a revised form of the Multidimensional Pain...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::Self-administered patient-centered questionnaires have been shown to be practical, reliable and valid in terms of evaluating functional limitations in rheumatic diseases. In systemic sclerosis a modified version of the HAQ and condition-specific questionnaires have been used. The Health Assessment Questionnaire (HAQ) ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-004-0674-4
更新日期:2004-12-01 00:00:00
abstract::The Churg-Strauss syndrome is a disorder characterized by hypereosinophilia and systemic vasculitis occurring in patients with asthma and allergic rhinitis. Only few patients are identified as having this syndrome. The three histological criteria are necrotizing vasculitis, tissue infiltration by eosinophils, and extr...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::Ocular manifestation of sarcoidosis occurs in up to 60% of patients with confirmed systemic sarcoidosis and represents one of the most common forms of noninfectious uveitis. In known pulmonary sarcoidosis, ocular involvement can occur in up to 80% of cases. Sarcoidosis can also present only in the eye, without a syste...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-017-0303-7
更新日期:2017-06-01 00:00:00
abstract::Heberden nodes affect mainly middle-aged women. Inheritance is autosomal dominant in female and autosomal recessive in male patients. We report the case of a young man who presented already with 12 years of age with pain in the distal finger joints. There were no other clinical or serological signs for other rheumatoi...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s003930050158
更新日期:1999-04-01 00:00:00
abstract::Up to now stratified therapy concepts have not played an important role in the treatment of patients with rheumatoid arthritis; however, a high heterogeneity regarding the effectiveness of therapies and occurrence of side effects in patients with the same indications provokes research efforts aiming at identifying and...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-011-0883-6
更新日期:2013-02-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disease. Standard treatment consists of chronic therapy with antimalarials, glucocorticoids and immunosuppressive/cytotoxic drugs, which is associated with considerable side effects. In contrast, immunoablation of autoreactive immunologic memory follo...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-008-0391-5
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Sport is becoming increasingly more important in our society. Due to the changing age spectrum with a greater number of elderly and substantially more active people, an increasing number of people with underlying orthopedic diseases are becoming interested in participating in sport. MATERIAL AND METHODS:Thi...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-013-1341-4
更新日期:2014-06-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a chronic autoimmune disease of still unknown etiology that results in characteristic destructive changes of the joints. Research of the past years has demonstrated that synovial fibroblasts play a central role in the initiation and perpetuation of these destructive changes. Stimulation of...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-007-0181-5
更新日期:2007-07-01 00:00:00
abstract::Rheumatoid vasculitis usually occurs on the background of seropositive rheumatoid arthritis, although in rare cases the patients can be seronegative. We report a woman with seronegative rheumatoid arthritis with rheumatoid vasculitis who developed toxic epidermal necrolysis involving most of her body surface area, whi...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-015-1632-z
更新日期:2016-03-01 00:00:00