Abstract:
:Aortic aneurysm and dissection are rare complications of systemic lupus erythematosus (SLE). The incidence, etiology, risk factors, and outcomes of this entity were largely unknown.The study materials were based on the publications of aortic aneurysm or dissection due to SLE published between 2000 and 2017.A total of 36 articles reporting a single case or case series involving 40 patients were collected. The patients showed an absolute female dominance at a mean aneurysm age of 44.6 years. Steroid use was 13.3 ± 9.4 years prior to admission for management of aortic aneurysm or dissection. Aortic aneurysm occurred more commonly in abdominal than other segments of the aorta, whereas aortic dissection did not show any location predilection. Patients with open aortic operations showed a higher mortality rate than other groups; however, no statistical significance was reached. Interventional therapy was minimally invasive, but postinterventional endoleaks were a concerning problem.SLE patients had significant risks for developing aortic aneurysm and dissection. Hypertension, long-term steroid use, and aortic pathological changes related to SLE seemed to be predominant risk factors for the occurrence of aortic aneurysm and dissection. Upon diagnosis, a surgical, interventional, or hybrid treatment should be performed to prevent severe sequelae and sudden deaths.
journal_name
Z Rheumatoljournal_title
Zeitschrift fur Rheumatologieauthors
Yuan SMdoi
10.1007/s00393-018-0555-xsubject
Has Abstractpub_date
2019-04-01 00:00:00pages
287-294issue
3eissn
0340-1855issn
1435-1250pii
10.1007/s00393-018-0555-xjournal_volume
78pub_type
杂志文章,评审abstract::Cell-based therapeutical approaches are already in clinical use and are attracting growing interest for the treatment of joint defects. Mesenchymal stem and precursor cells (MSC) cover a wide range of properties that are useful for the regeneration process of bone and cartilage defects. The following article is an ove...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-008-0396-0
更新日期:2009-05-01 00:00:00
abstract::The commission "Rehabilitation" of the German Society of Rheumatology compiled a data set for a routine report of the rehabilitation system for muskuloskeletal diseases. More than 250 rehabilitation hospitals offer inpatient rehabilitation for patients with musculoskeletal diseases. The prevalence of inpatient rehabil...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-005-0626-7
更新日期:2005-06-01 00:00:00
abstract::Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::A female patient developed systemic rash, lung edema, electrocardiogram (ECG) abnormalities and fulminant hepatitis with partial liver failure 4 weeks after the start of sulfasalazine treatment. Peripheral T-cell activation, a positive PCR test for human herpesvirus (HHV) 6 as well as eosinophilia in bronchial lavage ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-013-1308-5
更新日期:2014-03-01 00:00:00
abstract::Due to their anti-inflammatory effects and their capacity to affect the synthesis of most cytokines and the Th1/Th2 balance, endogenous glucocorticoids contribute to control the basal operation of immune cells. Immune processes result in the production of cytokines, such as IL-1, IL-2, IL-6, IL-11, IL-12, TNF-alpha, a...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s003930070014
更新日期:2000-01-01 00:00:00
abstract::Since 1978 a 63-year-old woman with rheumatoid arthritis received D-penicillamine (D-PA) in a daily dose of 250-500 mg (mean 300 mg/d). In 1982 the patient complained of diplopia for several days, the ophthalmological and neurological examinations three days later were normal. In July 1983 she developed a myasthenic s...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract::The knee joint is often involved in rheumatoid arthritis. Despite ever-improving medical antirheumatic therapies, surgical treatment continues to play an important role in optimal multidisciplinary care. The aim of the present work is to process current orthopedic surgical therapy procedures on the knee joint accordin...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-018-0534-2
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Patients with rheumatoid arthritis (RA) tend to be less physically active. Physical activity has been shown to have a positive impact on disease activity and quality of life and is recommended by the European League Against Rheumatism (EULAR) as an integral component of standard treatment. OBJECTIVE:A cross...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-020-00830-2
更新日期:2020-06-25 00:00:00
abstract::In recent years, new findings in immunology have been successfully converted to therapeutic principles, in particular for rheumatoid arthritis (RA) and spondylarthritides. The introduction of cytokine blockers in RA using tumor necrosis factor (TNF)-alpha and interleukin (IL)-1 inhibitors presented the first original ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-009-0436-4
更新日期:2009-07-01 00:00:00
abstract::Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::A 41-year-old patient with mutilating rheumatoid arthritis and progressive systemic sclerosis, who developed a chronic myeloproliferative disorder polycythemia vera was observed. Some of the pathogenetic aspects of this case with special respect to the function abnormalities of peripheral blood polymorphonuclear cells...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::Commonly-used serological methods for the determination of Yersinia antibodies are based on the presence of agglutinins, which are frequently absent or of low titer when arthritis begins. Stool cultures are usually negative at that time, so many Yersinia infections are underdiagnosed. On the other hand, significant ag...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract::The effect of D-penicillamine, given for 14 days in doses of 100 mg/kg and 225 mg/kg, upon the collagen metabolism of skin and bone tissues was studied in rats. The smaller dosage of D-penicillamine did not effect the collagen synthesis in skin or bone. When the higher dosage was used, however, an increase of collagen...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::Large data bases and the projects arising from them have led to a much improved understanding of systemic sclerosis over the last decade. Serology has developed further so that more autoantibodies are available for routine testing. Capillary microscopy has become standard and relevant progress has also been made in th...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-014-1550-5
更新日期:2015-03-01 00:00:00
abstract::Twelve patients with osteoarthrosis were locally treated with Felbinac Gel (biphenyl acetic acid (BPAA) 3%) three times daily for 14 days (five patients), 28 days (six patients) or 42 days (one patient) before elective knee joint surgery. BPAA plasma concentrations as of the seventh day of treatment were steady at bet...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::278 patients with ankylosing spondylitis have been studied in order to find a basis for prognosis by setting a mobility function index of the vertebral column. This index does not depend on manifestation age or on the blood sedimentation rate. It increases with progression of x-ray findings. A coincidence of impaired ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1975-11-01 00:00:00
abstract::An attempt is made to compile the pharmacological data on the leading non-steroidal anti-inflammatory drugs. They concern the pharmacodynamics, the pharmacokinetics and the unwanted effects of these compounds. From these data a few suggestions for rational use are made: Ibuprofen and diclofenac present as drugs with s...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Patients with various kinds of intestinal illnesses sometimes suffer not only abdominal symptoms, but also joint involvement, leading to a reduction in quality of life. Diseases leading to inflammatory joint involvement such as inflammatory bowel disease, Whipple's disease or surgical intestinal bypass, are classified...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-009-0465-z
更新日期:2009-06-01 00:00:00
abstract::The correlation of the determination of antinuclear antibodies, as shown by consumption tests and immunofluorescence was investigated in a collective of 100 sera of patients suspected for SLE, collagenosis and rheumatoid arthritis, sent for routine screening investigation. The results of both methods correlated in 78%...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1976-05-01 00:00:00
abstract::An appropriate treatment of elderly rheumatic patients implements comprehensive diagnostics and exclusion diagnostics of e.g. coronary heart disease, osteoporosis, renal failure, diabetes mellitus type 2 and thyroid gland dysfunction. Furthermore, the complex disease situation might require the integration of other fa...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-012-1115-4
更新日期:2013-08-01 00:00:00
abstract::A multicentric post-marketing surveillance study over 7 years including 5,124 patients is presented. According to clinical and laboratory data, the drug D-penicillamine was effective, with a tendency of loss of efficacy after therapy of 5 years or longer. Response was better in the early stage of the disease. Side eff...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Systemic sclerosis is a rare rheumatologic disease that is characterised by skin and organ fibrosis as well as vascular changes and the occurrence of specific autoantibodies. It has a high morbidity and mortality while its manifestations show significant heterogeneity in patients. Thus, diagnosis and follow-up of pati...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-019-0639-2
更新日期:2019-06-01 00:00:00
abstract::Patients with rheumatic diseases need a comprehensive and interdisciplinary treatment. In this context patient education takes the part to lead patients to a better self-management. The goals of patient education are the increase of knowledge and introspection, the positive influencing of attitudes and self-efficacy a...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-003-1202-7
更新日期:2003-01-01 00:00:00
abstract::A dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis was found in animal models of chronic inflammatory diseases, and the defect was located in more central portions of the HPA axis. This defect of neuroendocrine regulatory mechanisms contributes to the onset of the model disease. Since these first observati...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::Based on the most recent studies, it clearly appears that long-term hormone replacement therapy (HRT) prevents fractures but does not improve established coronary artery disease. In addition, HRT leads to a small increase in breast cancer incidence and to a decrease in colorectal cancer incidence. HRT increases the in...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s00393-003-0559-y
更新日期:2003-12-01 00:00:00
abstract::Sjögren's syndrome is a systemic inflammatory rheumatic disorder of unknown origin with so far inadequate therapy options. Management of Sjögren's syndrome is still primarily palliative using local symptomatic measures, and if appropriate glucocorticoids, NSAIDs and immunosuppressive drugs. New clues to the pathogenes...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-007-0231-z
更新日期:2007-12-01 00:00:00
abstract::A few days after the SARS-CoV-2 infection was declared a pandemic, the German Society for Rheumatology (DGRh) compiled first recommendations for the care of patients with inflammatory rheumatic diseases (IRD). These first recommendations were based on an expert consensus and were largely non-evidence-based. Now that t...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,实务指引,评审
doi:10.1007/s00393-020-00851-x
更新日期:2020-09-01 00:00:00
abstract:UNLABELLED:The regulatory region of the corticotropin releasing hormone (CRH) is highly conserved and plays a crucial role in the response of the organism to stress. Release of CRH initiates a cascade of events leading to the release of cortisone and the regulation of inflammatory and immune events. OBJECTIVE:Since it...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s003930050002
更新日期:2000-02-01 00:00:00
abstract::Osteoarthritis is the most common joint disease. In addition to known risk factors e.g. genetics, age and hormonal status it has been suggested that chronic-repetitive micro- and substantial (macro-) injury may play an important pathogenetic role. In a longitudinal case-study we examined Judo-players for clinical and ...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章
doi:10.1007/s003930050048
更新日期:1997-12-01 00:00:00
abstract::The international treat-to-target initiative including rheumatoid arthritis (RA) patients has defined remission or alternatively low disease activity as treatment goals. In Germany representatives of the medical profession, such as doctors, nurses and including the Deutsche Rheuma-Liga, are deliberating how to adapt a...
journal_title:Zeitschrift fur Rheumatologie
pub_type: 杂志文章,评审
doi:10.1007/s00393-011-0773-y
更新日期:2011-10-01 00:00:00