Abstract:
OBJECTIVE:To study the psychological effects of multifetal pregnancy reduction. DESIGN AND SETTING:Hour-long semistructured telephone interviews with both multifetal pregnancy reduction patients and control subjects. PATIENTS:Forty-two multifetal pregnancy reduction patients were contacted within 1 year of undergoing the procedure. Forty-four control subjects had become pregnant after infertility evaluation or treatment but conceived only a single fetus or twins and thus did not consider fetal termination. MAIN OUTCOME MEASURES:Standardized measures of depressive disorder and current psychiatric symptoms, as well as questions about emotional reactions to multifetal pregnancy reduction. RESULTS:Reduction patients who were pregnant or postpartum at the time of the interview (n = 34) were no more likely than pregnant or postpartum controls (n = 34) to report episodes of depression or high psychiatric symptom levels. The same proportion (14.7%) of both reduction patients and controls with a successful pregnancy outcome met criteria for an episode of major depressive disorder occurring during the 9 months before the interview. In contrast, the 8 reduction patients who spontaneously aborted the entire pregnancy and the 10 controls who spontaneously aborted reported significantly higher rates of the full depressive syndrome. CONCLUSIONS:Multifetal pregnancy reduction is experienced as stressful and distressing. However, when pregnancy outcome is successful, the medical intervention does not put women at significant risk for affective illness or elevated levels of psychiatric symptoms.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
McKinney M,Downey J,Timor-Tritsch Isubject
Has Abstractpub_date
1995-07-01 00:00:00pages
51-61issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(16)57654-7journal_volume
64pub_type
杂志文章abstract::Well-designed and -conducted clinical trials are needed to further advance the field for reproductive medicine. However, current reporting of outcomes of trials is ambiguous and disparate. In this review it is offered that the preferred outcome for clinical trials in reproductive medicine should be live birth. Multipl...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2014.03.026
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:The present study examines the safety, effectiveness, and local tissue response for a new transcervical fallopian tube permanent contraceptive device, the STOP device (Conceptus, Inc., San Carlos, CA). DESIGN:Nonrandomized prospective evaluation of tubal occlusion and histologic response. SETTING:Inpatient,...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)02858-8
更新日期:2001-11-01 00:00:00
abstract::Adhesion formation after laparoscopic surgery was evaluated in mice of different strains. More adhesions were observed in Swiss, NMRI, and BALB/c mice, with less interanimal variability in BALB/c mice. These data point to genetics effects on adhesion formation, which open new insights in its pathogenesis and indicate ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.11.084
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:To compare conventional two- (2-D) and three-dimensional (3-D) scanning of the uterine cavity with and without saline contrast medium. DESIGN:Observational pilot study. SETTING:University-based fertility service. PATIENT(S):Ten IVF patients requiring uterine cavity assessment. INTERVENTION(S):Two-dimensio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58651-8
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To assess the clinical relevance of daily hormonal changes for achieving a successful pregnancy in anovulatory infertile women. DESIGN:A comparative study of hormonal dynamics in pregnant and nonpregnant cycles during the pulsatile subcutaneous administration of hMG. Subjects received subcutaneous injection ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)56093-2
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVE:To determine the influence of ejaculatory abstinence on within-subject semen parameters and DNA fragmentation. DESIGN:Prospective study. SETTING:Private infertility institute and university-based research laboratory. PATIENT(S):Sixteen consenting male volunteers undergoing infertility investigation. INTER...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.03.014
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:To describe the association of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and thrombocytopenia-absent radius (TAR) syndrome. DESIGN:Descriptive case report. SETTING:Tertiary university-affiliated care and referral facility. PATIENT(S):A 22-year-old woman with TAR syndrome referred to our department wit...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.06.077
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To investigate the serum pattern of free leptin, bound leptin, and soluble leptin receptor throughout the physiological menstrual cycle. DESIGN:Prospective observational study. SETTING:Tertiary care center for gynecological endocrinology and reproductive medicine and a university research laboratory. PATIE...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2003.06.020
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVE:To determine the clinical significance of albumin determination in ejaculates by means of an easy office test to screen semen samples for subclinical infection-inflammation. PATIENTS:One hundred fifty-nine randomly chosen males of couples with longstanding infertility (median duration of infertility 4 years ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:To assess the single-dose pharmacokinetics of a recombinant human FSH preparation (Gonal-F; Laboratoires Serono, Aubonne, Switzerland), administered by i.v., IM, and SC routes and its pharmacokinetics at steady state after multiple dosing by the SC route. DESIGN:Twelve healthy down-regulated female volunteer...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-04-01 00:00:00
abstract:OBJECTIVE:To investigate the role of sonographic parameters in assessing endometrial receptivity in an in vitro fertilization (IVF) program. DESIGN:Prospective clinical study. SETTING:University setting. PATIENT(S):One hundred thirty-five patients in our IVF program, selected prospectively on the day of oocyte retri...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01695-2
更新日期:2001-02-01 00:00:00
abstract::Semen samples from 25 fertile donors and 34 infertility patients were analyzed and evaluated both fresh and frozen with the zona-free hamster egg penetration test (EPT) and the bovine cervical mucus penetration test (MPT). Cryopreserved sperm penetrated 47.2% (average) of the hamster eggs, and fresh sperm penetrated 5...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47067-6
更新日期:1983-05-01 00:00:00
abstract:OBJECTIVE:To measure the flow velocity of the uterine and ovarian arteries through the menstrual cycle to determine there are changes. DESIGN:Serial measurements throughout the menstrual cycle in women attending an infertility clinic, compared with volunteers coming for annual examinations. Transvaginal ultrasound-col...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54657-3
更新日期:1991-11-01 00:00:00
abstract::On the basis of studies in monkeys, the hypothesis has been proposed that vasectomy induces the formation of circulating immune complexes (CICs), which--via activation of the complement system--may result in immune injury of the endothelium and thereby exacerbate atherosclerosis; the same mechanism has been suggested ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1982-06-01 00:00:00
abstract:OBJECTIVE:To assess long-term fracture risk after hysterectomy, with or without oophorectomy. DESIGN:Population-based, cohort study. SETTING:Olmsted County, Minnesota. PATIENT(S):Women residing in Olmsted County (n = 9,258) who underwent hysterectomy in 1965-2002, compared to an equal number of age- and sex-matched ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.11.080
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To introduce a technique for hysteroscopic resection of submucous myoma arising from the uterine fundus. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 43-year-old nulliparous Japanese woman. INTERVENTION(S):An original combination technique of hysteroresectoscopy using circumferential myom...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.03.066
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To investigate the biocompatibility of a novel copper-containing composite to provide preclinical data for clinical application of intrauterine device (IUD) or intra-vas device (IVD). DESIGN:Prospective experimental study. SETTING:Good laboratory practices laboratories. ANIMALS:Twenty healthy adult mice (S...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.04.041
更新日期:2011-03-15 00:00:00
abstract:OBJECTIVE:To report on a one-year experience participating in a capitated healthcare plan for infertility. DESIGN:Prospective study. SETTING:University population. PATIENT(S):Reproductive-age women 15 to 50 years. INTERVENTION(S):The first-generation Lewin infertility algorithm and CATHI software were used to negot...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)01673-9
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the positive predictive value (PPV) and negative predictive value (NPV) of FISH analysis and to determine which chromosomal abnormalities are most frequently confirmed. DESIGN:Prospective observational. SETTING:IVF laboratory. PATIENT(S):Two hundred forty-one embr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.07.1337
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To determine the relationships between sperm acrosin activity, sperm morphology evaluated according to strict criteria, visually observed acrosomal morphology, and IVF rates. DESIGN:Prospective analytic study. Acrosin activity was determined on all semen samples together with a standard semen analysis. Empha...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58167-9
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:To assess the effect of gonadotropin-releasing hormone agonist (GnRH-a) on pituitary suppression, subsequent ovarian response, and results of in vitro fertilization (IVF) treatments in polycystic ovarian syndrome (PCOS) patients. DESIGN:Randomized prospective study. SETTING:In vitro fertilization program an...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54847-x
更新日期:1992-02-01 00:00:00
abstract::Fresh and aged (24 hours after ovulation) human oocytes and recently ovulated mouse oocytes may be activated by exposure to acidified Tyrode's solution. No activation of either type of human oocyte was observed after exposure to hyaluronidase or pronase, but significant numbers of fresh mouse oocytes were activated af...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53279-8
更新日期:1990-02-01 00:00:00
abstract:OBJECTIVE:To summarize the procedures and outcomes of assisted reproductive technology (ART) initiated in the United States in 1994. DESIGN:Data were collected on the Society for Assisted Reproductive Technology (SART) Database program and submitted to KMPG Peat Marwick, who served as the 1994 collection center for th...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58621-x
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To review the available information regarding the polypeptide factors inhibin, activin, and follistatin in reproductive physiology. DESIGN:The protein structure, tissue expression, regulation, and effects of these factors are outlined, with an emphasis on the reproductive tissues in both females and males. A...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)58137-0
更新日期:1996-03-01 00:00:00
abstract::Most oocyte donation programs have experienced higher pregnancy rates than usually seen in regular in vitro fertilization (IVF), suggesting that the quality of either the oocytes or the endometrium is superior. To clarify this issue we analyzed the results of transfers of 136 cryopreserved embryos originating either f...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53830-8
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between carriage of BRCA1/2 mutations and ovarian performance, as demonstrated by in vitro fertilization (IVF) outcomes. DESIGN:Retrospective cohort study. SETTING:Two tertiary IVF centers. PATIENT(S):BRCA mutation carriers undergoing IVF for preimplantation genetic diagnosis (P...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2015.07.1162
更新日期:2015-11-01 00:00:00
abstract::The International Committee for Monitoring Assisted Reproductive Technology's 7th World Report for the year 2000 analyzes wide variations in live and multiple birth rates from 49 countries and six regions by type of assisted reproductive technology, age, number of embryos transferred, and multiple births. More than 46...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.01.011
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To determine the level of standardization in performance of the semen analysis among clinical laboratories in the United States. DESIGN:A survey was mailed to laboratories requesting information about the laboratory and performance of the semen analysis. Responses were received from 536 laboratories. SETTIN...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)03296-x
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the mRNA levels of connexins in different sizes of luteinized follicles. DESIGN:Semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) to determine the connexin mRNA levels in the granulosa cells of 91 luteinized follicles. SETTING:Academic tertiary care medical center and res...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2003.05.015
更新日期:2003-12-01 00:00:00
abstract::A monoclonal antibody that induces agglutination of human sperm was used to localize the interacting antigen in various tissues by indirect immunofluorescence. The antibody localized to the immature sperm and Sertoli cells of the seminiferous tubules, simple cuboidal epithelial cells of the rete testis, and the column...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)48147-1
更新日期:1984-10-01 00:00:00