Lack of standardization in performance of the semen analysis among laboratories in the United States.

Abstract:

OBJECTIVE:To determine the level of standardization in performance of the semen analysis among clinical laboratories in the United States. DESIGN:A survey was mailed to laboratories requesting information about the laboratory and performance of the semen analysis. Responses were received from 536 laboratories. SETTING:Clinical laboratories enrolled in the American Association of Bioanalysts Andrology Proficiency Testing Program. PATIENT(S):None. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Agreement among laboratories. RESULT(S):Sixty-one percent of respondent laboratories were part of an assisted reproductive technology program. The laboratories perform less than 50 (53%), less than 10 (25%), or less than 5 (16%) andrology laboratory procedures per month. The laboratories routinely report sperm count (94% of laboratories), motility (95%), morphology (85%) and forward progression (69%), and semen volume (96%) as part of the semen analysis. Only 64% of laboratories routinely report abstinence, and 60% of laboratories indicate the criteria used for sperm morphology on the report form. The most common lower limits of normality for sperm count and motility were >20 x 10(6)/mL (77% of laboratories) and >50% (59% of laboratories), respectively. Few laboratories performed quality control for sperm counts (29%), motility (41%), and morphology (41%). CONCLUSION(S):These data indicate a significant lack of standardization in the performance and reporting of semen analyses among laboratories in the United States.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Keel BA,Stembridge TW,Pineda G,Serafy NT Sr

doi

10.1016/s0015-0282(02)03296-x

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

603-8

issue

3

eissn

0015-0282

issn

1556-5653

pii

S001502820203296X

journal_volume

78

pub_type

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