Clone Q379 immunoscreened from a Chinese HCV cDNA lambda gt11 library.

Abstract:

:A Chinese HCV cDNA clone, designated as Q379, 379 nucleotides in length, was selected by recombinant immunoscreening from a random-primed Chinese HCV lambda gt11 library. DNA sequencing demonstrated that Q379 situated from positions 7314 to 7695 at NS5 region corresponded with the American prototype HCV nucleotide sequence. The homologies of Q379 with the equivalent sequences of the prototype were found to be 72.8% in nucleotides and 73.8% in amino acids, respectively. Hydrophobicity profile shows that Q379-encoded polypeptide (126 amino acid residues) contains two hydrophilic areas. This Chinese HCV clone would be valuable in basic and clinical studies of Chinese HCV infection.

journal_name

Curr Microbiol

journal_title

Current microbiology

authors

Qi Z,Arima T

doi

10.1007/BF01571058

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

161-3

issue

3

eissn

0343-8651

issn

1432-0991

journal_volume

28

pub_type

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