Abstract：
:The distribution of radioactivity in the rat hypothalamus after intraventricular injection of tritiated luteinizing hormone-releasing hormone (LH-RH) was studied by autoradiography and compared with that expected from Fick's second law which defines the character of ordinary diffusion. The results suggest that LH-RH penetrates through the ependyma and thin subependymal layer in the median eminence and into the suprachiasmatic area by ordinary diffusion. By contrast, concentration of radioactivity in outer layers of the median eminence is increased and, therefore, can not be explained by the diffusion law. In this region incorporation of radioactivity into cell bodies was demonstrated. In the subependymal layer of the median eminence a few rows of silver grains seemingly located in cellular processes were also observed. The diffusion coefficient in the periventricular zone was lower than that in the deeper tissue. It is suggested that the ependymal-subependymal complex of the third and lateral ventricles acts as passive membrane towards LH-RH contained in the cerebrospinal fluid. The significance of this mechanism for the intrahypothalamic transport of RH's is discussed.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Goldgefter Ldoi
10.1007/BF00215317subject
Has Abstractpub_date
1976-05-13 00:00:00pages
411-8issue
3eissn
0302-766Xissn
1432-0878journal_volume
168pub_type
杂志文章abstract：:The choroid plexus from the lateral ventricles of 18-day chick embryos was cultivated as an organ in medium 199 until the degeneration of the stroma. Selected plexuses forming an empty epithelial sac were then incubated with enzyme-treated human immunoglobulin (5S-antibody) and with native human immunoglobulin (7S-ant...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00237886
更新日期：1980-01-01 00:00:00
abstract：:The spatial localisation of insulin-like growth-factor-binding protein-2 (IGFBP-2) and its mRNA was investigated during larval and post-larval developmental stages of the gilthead seabream ( Sparus aurata) by immunohistochemistry and in situ hybridisation with specific antisera and riboprobes. During larval developmen...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0952-0
更新日期：2005-01-01 00:00:00
abstract：:The effects of dexamethasone on the ability of cells enzymatically isolated from 21-day fetal rat calvaria to produce cartilage in vitro has been investigated. Primary cultures of single-cell suspensions of rat calvaria were grown for up to 28 days in vitro in alpha-minimal essential medium containing 15% fetal bovine...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224728
更新日期：1989-04-01 00:00:00
abstract：:Prostatic carcinoma affects 1 in 11 men and targets bone with sclerotic metastases. The study of prostate carcinoma growth in bone has been hampered by the lack of suitable animal models. We have developed an in vivo model of prostate carcinoma growth in bone by inoculating three human prostate carcinoma cell lines (P...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0503-x
更新日期：2002-03-01 00:00:00
abstract：:The innervation of the anococcygeus muscle of the rat was investigated with regard to the histochemical features of nerve fibers within the muscle and to the location of the postganglionic autonomic neurons which are the source of these fibers. Acetylcholinesterase-positive fibers and catecholaminergic fibers are abun...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00571438
更新日期：1990-01-01 00:00:00
abstract：:Nematocysts are characteristic organelles of the phylum Cnidaria. The free-living Platyhelminth Microstomum lineare preys on Hydra oligactis and sequesters nematocysts. All nematocyst types become phagocytosed without adherent cytoplasm by intestinal cnidophagocytes. Desmoneme and isorhiza nematocysts disappear within...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03149-w
更新日期：2020-01-01 00:00:00
abstract：:The ultrastructure of the isolated glycerinated penis retractor muscle (PRM) of Helix pomatia was investigated. The diameter distributions of thick myofilaments from birbre cross sections in the relaxed, phasic contracted, tonic contracted, and in the catch state.s show that a characteristic filament spectrum is forme...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221808
更新日期：1975-01-01 00:00:00
abstract：:Purinergic P2X receptors associated with the parasympathetic nerves supplying human bladder smooth muscle (detrusor) are implicated in control of detrusor contractility. The relative abundance of all seven subtypes colocalised with synaptic vesicles on parasympathetic nerves was examined in specimens from normal adult...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0788-z
更新日期：2003-12-01 00:00:00
abstract：:A major difficulty in the investigation of interstitial cells of Cajal (ICC) is in identifying these cells within intact, living gastrointestinal tissues. To overcome this difficulty we developed a method to visualize ICC in the myenteric plexus region (ICC-MP) of the guinea pig ileum. Cells were identified with Nomar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0474-y
更新日期：2002-01-01 00:00:00
abstract：:The bilaterally paired cercal nerves of Archimantis brunneriana Sauss. leave the terminal ganglion posteriorly and then turn dorsally through muscles at the rear of the abdomen to enter the cerci, where each splits into two branches; successive branchings occur further distally in each cercus. In the distal nerve bran...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217267
更新日期：1982-01-01 00:00:00
abstract：:Elevated target-derived smooth muscle nerve growth factor (NGF) and resultant neurogenic plasticity are associated with both hypertension and hyperactive voiding in spontaneously hypertensive rats (SHRs: hypertensive, behaviorally hyperactive). In culture, vascular (VSMCs) and bladder (BSMCs) smooth muscle cells deriv...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051194
更新日期：1998-12-01 00:00:00
abstract：:Biocytin, recently introduced in neuroanatomical studies, was used as a retrograde tract tracer in combination with immunofluorescence in order to analyse the neurochemical characters of some central neuronal projections to the pars intermedia in two amphibian species, the anuran Rana esculenta and the urodele Trituru...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050754
更新日期：1997-02-01 00:00:00
abstract：:Prolonged secretory stimulation of the exocrine pancreas in the rat by in vivo infusion of caerulein leads to a rapid degranulation of the organ associated with a progressive reduction in the size of the zymogen granules. During the first six to twelve hours of stimulation Golgi complexes are enlarged and several stru...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224474
更新日期：1976-01-28 00:00:00
abstract：:Pax genes are expressed in specific patterns in the nervous system during development and in the adult. Recent findings suggest a link between the expression of Pax-2 and axonal guidance. Mice with a targeted deletion of Pax-2 are an excellent tool for studying axonal pathfinding at the molecular level, especially wit...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410050923
更新日期：1997-11-01 00:00:00
abstract：:The central fat body of the ovoviviparous cockroach Nauphoeta cinerea was studied during the first reproductive cycle of the female by means of light microscopy, autoradiography and electron microscopy. Comparative studies in larval stages were also undertaken. The fat body of Nauphoeta contains a large amount of lipi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219785
更新日期：1978-04-28 00:00:00
abstract：:We have tested the suggestion that the reported increase, in hypoxic rats, in the number of lung endocrine cells immunoreactive for the regulatory peptide CGRP is caused by an accumulation of peptide within the cells which renders them more detectable, rather than by a real increase in proliferation. The incorporation...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00338049
更新日期：1992-04-01 00:00:00
abstract：:Neurotrophins NGF, BDNF, NT-3, and NT-4/5 are members of the neurotrophin family of proteins, which support the survival and induce differentiation of vertebrate neurons. We have studied the effects of neurotrophins on growth cones of embryonic sensory neurons. BDNF and NT-4/5 cause growth cone collapse and transient ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410050933
更新日期：1997-11-01 00:00:00
abstract：:The morphology of enterochromaffin (EC) cells in the human fundic mucosa was investigated at the light-microscopic level by means of the unlabeled peroxidase anti-peroxidase method, with the use of a highly specific anti-serotonin serum. EC-cells in the human fundic mucosa were sparsely distributed below the neck port...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226973
更新日期：1984-01-01 00:00:00
abstract：:Neuromuscular terminals of a single motoneuron to four muscles (CPV7a, GM5a, CV2, and CV3) in the stomach of the blue crab Callinectes sapidus showed structural evidence for the exocytotic release of dense-core vesicles exclusively at synapses. The primary evidence was the appearance of dense cores in the synaptic cle...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050897
更新日期：1997-09-01 00:00:00
abstract：:The fine structure of luminal surface of clearly identified portions of uriniferous tubules has been studied by scanning electron microscopy to elucidate some controversies concerning the topography of certain surface formations. The results show a characteristic pattern of the luminal surface in the region of Henle's...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215128
更新日期：1976-02-06 00:00:00
abstract：:An increasingly pro-oxidant environment has been widely implicated in causing dysfunction of testicular steroidogenesis, but little progress has been made in understanding the underlying molecular mechanism. Here, we report that gamma-glutamyl transferase 5 (GGT5), a key metabolism component responsible for the cataly...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2458-y
更新日期：2016-11-01 00:00:00
abstract：:The fine structure of the kidney is studied in the sexually mature male three-spined stickleback after administration of an antiandrogen, cyproterone acetate. Under these conditions, the dedifferentiation of renal tubules is characterized by the same involutive processes as those induced by castration, with the differ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220324
更新日期：1976-10-13 00:00:00
abstract：:Progenitor stem cells have been identified, isolated and characterized in numerous tissues and organs. However, their therapeutic potential and the use of these stem cells remain elusive except for a few progenitor cells from bone marrow, umbilical cord blood, eyes and dental pulp. The use of bone marrow-derived hemat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-012-1471-z
更新日期：2012-10-01 00:00:00
abstract：:Apoptosis is a form of programmed cell death that occurs in neurons during development of the nervous system and may also be a prominent form of neuronal death in chronic neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Recent findings also implicate apoptosis in neuronal degeneration after is...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004419900154
更新日期：2000-07-01 00:00:00
abstract：:The structure of the two integumental layers comprising the carapace of female D. magna was examined at several points through the molt cycle. The epicuticle and procuticle are simple in organisation; pore canalsare absent but intracuticular fibres are present, forming complexes with invaginations of the epidermal pla...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214213
更新日期：1976-06-14 00:00:00
abstract：:Some non-endocrine cells in the pituitary anterior lobe are responsible for providing stem/progenitor cells to maintain hormone-producing cells. In particular, cells expressing S100β protein, a calcium-binding protein, have been hypothesized to be a pituitary cell resource. Accumulating data have revealed that S100β-p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1890-0
更新日期：2014-09-01 00:00:00
abstract：:The development of the canine proximal colon from the completion of organogenesis through 43 days after birth was studied using light microscopy, immunofluorescence and electron microscopy. During this period the tunica muscularis increased in thickness from 42+/-6 microm in animals midway through the gestation period...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00319136
更新日期：1995-10-01 00:00:00
abstract：:Interstitial cells of Cajal (ICC) are important regulatory cells in the smooth muscle coats of the digestive tract. Expression of the Kit receptor tyrosine kinase was used in this study as a marker to study their distribution and development in the striated musculature of the mouse esophagus. Sections and whole-mounts...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100418
更新日期：2001-10-01 00:00:00
abstract：:The circadian timing system is a neural network consisting of the hypothalamic suprachiasmatic nucleus, aided by the retina, other hypothalamic nuclei, autonomic regions of the spinal cord, sympathetic ganglia and the pineal gland. Extensive studies conducted over the last two decades have unravelled the principal ite...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410050652
更新日期：1996-09-01 00:00:00
abstract：:Transplantation of a small fragment of the ileum beneath the kidney capsule in syngenic mice results in the formation of a cyst lined with proliferating intestinal epithelium. The duration of the cell cycle in the epithelium was determined (using tritiated thymidine and the FLM method) as 14.5 h, as compared with 11.5...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221125
更新日期：1977-02-02 00:00:00
