Analgesics and cancers of the renal pelvis and ureter.

abstract：:Regression of EB-virus-induced transformation occurs exclusively in cultures of leukocytes from seropositive donors. Studies have shown that the strength of regression could be assayed in terms of the proportion of T cells which must be added to the autologous EB virus-infected T-cell-depleted population in order to e...

journal_title：International journal of cancer

authors： Rickinson AB,Moss DJ,Pope JH

更新日期：1979-05-15 00:00:00

abstract：:Phenotypic and functional characteristics of tumor-infiltrating lymphocytes (TIL) obtained from human primary and metastatic liver tumors were studied. Lymphocytes isolated from 18 tumors and autologous (A) peripheral blood (6 cases) were phenotyped by 2-color flow cytometry and cloned in a limiting dilution system, w...

journal_title：International journal of cancer

authors： Shimizu Y,Iwatsuki S,Herberman RB,Whiteside TL

更新日期：1990-11-15 00:00:00

abstract：:Women affected by gross cystic disease of the breast have an increased risk of breast cancer. We report here the incidence of breast cancer by cyst type and intracystic epidermal growth factor (EGF) concentration. Our retrospective study included 504 women who had at least 1 cyst aspiration between 1985 and 1993. Cyst...

journal_title：International journal of cancer

authors： Boccardo F,Marenghi C,Ghione G,Pepe A,Parodi S,Rubagotti A

更新日期：2001-07-20 00:00:00

abstract：:We have addressed the role of bacterial co-infection in viral oncogenesis using as model Epstein-Barr virus (EBV), a human herpesvirus that causes lymphoid malignancies and epithelial cancers. Infection of EBV carrying epithelial cells with the common oral pathogenic Gram-negative bacterium Aggregatibacter actinomycet...

journal_title：International journal of cancer

authors： Frisan T,Nagy N,Chioureas D,Terol M,Grasso F,Masucci MG

更新日期：2019-01-01 00:00:00

abstract：:Cyclin D1 is a major positive regulator of the G1 restriction point promoting inactivation of the retinoblastoma protein (RB). The cyclin D1 gene is rearranged, amplified and/or over-expressed in several human neoplasms. In the present series of 64 human breast carcinomas, cyclin D1 amplification (4- to 8-fold) was se...

journal_title：International journal of cancer

authors： Barbareschi M,Pelosio P,Caffo O,Buttitta F,Pellegrini S,Barbazza R,Dalla Palma P,Bevilacqua G,Marchetti A

更新日期：1997-04-22 00:00:00

abstract：:Inhibition of programmed cell death (apoptosis) is associated with increased tumor aggressiveness. We hypothesized that a novel sensitive to apoptosis gene, SAG, may be expressed in tumors of patients with nonsmall cell lung cancer (NSCLC) and may affect their clinical outcome. Expression of SAG messenger RNA was eval...

journal_title：International journal of cancer

authors： Sasaki H,Yukiue H,Kobayashi Y,Moriyama S,Nakashima Y,Kaji M,Fukai I,Kiriyama M,Yamakawa Y,Fujii Y

更新日期：2001-11-20 00:00:00

abstract：:It is increasingly appreciated that host factors within the tumor center and microenvironment play a key role in dictating colorectal cancer (CRC) outcomes. As a result, the metastatic process has now been defined as a result of epithelial-mesenchymal transition (EMT). Establishment of the role of EMT within the tumor...

journal_title：International journal of cancer

authors： Roseweir AK,Kong CY,Park JH,Bennett L,Powell AGMT,Quinn J,van Wyk HC,Horgan PG,McMillan DC,Edwards J,Roxburgh CS

更新日期：2019-01-01 00:00:00

abstract：:Claudin7 (cld7) is a cancer-initiating cell (CIC) marker in gastrointestinal tumors, a cld7-knockdown (kd) being accompanied by loss of tumor progression. Tumor exosomes (TEX) restoring CIC activities, we explored the contribution of cld7. This became particularly interesting, as tight junction (TJ)- and glycolipid-en...

journal_title：International journal of cancer

authors： Kyuno D,Zhao K,Schnölzer M,Provaznik J,Hackert T,Zöller M

更新日期：2019-10-15 00:00:00

abstract：:Human epidemiological studies suggest that 1,25(OH)2 D3 deficiency might increase cancer incidence, but no spontaneous tumors have been reported in mice lacking 1,25(OH)2 D3 or deficient in its receptor. In our study, we detected, for the first time, diverse types of spontaneous tumors in l,25(OH)2 D3 deficient mice m...

journal_title：International journal of cancer

authors： Chen L,Yang R,Qiao W,Yuan X,Wang S,Goltzman D,Miao D

更新日期：2018-07-15 00:00:00

abstract：:Three lymphoblastoid cell lines were established from splenic lymphocytes of a lymphomatous baboon (Papio hamadryas) by co-cultivation of the lymphocytes with X-irradiated cells of marmoset or baboon lymphoblastoid cell cultures; the baboon splenic lymphocytes failed to grow when cultured alone. A herpesvirus, associa...

journal_title：International journal of cancer

authors： Falk L,Deinhardt F,Nonoyama M,Wolfe LG,Bergholz C

更新日期：1976-12-15 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. Emerging evidence indicates that tumour cells release substantial amounts of RNA into the bloodstream, in which RNA strongly resists RNases and is present at sufficient levels for quantitative analyses. ...

journal_title：International journal of cancer

authors： Xu W,Zhou G,Wang H,Liu Y,Chen B,Chen W,Lin C,Wu S,Gong A,Xu M

更新日期：2020-05-15 00:00:00

abstract：:The numbers of new cancer cases in 16 common sites occurring in 1980 have been estimated for 24 areas of the world for which the United Nations produces population estimates. For the world as a whole, the total number of new cases was 6.35 million, almost exactly evenly divided between the developed and developing cou...

journal_title：International journal of cancer

authors： Parkin DM,Läärä E,Muir CS

更新日期：1988-02-15 00:00:00

abstract：:Evidence from randomized controlled trials suggests that calcium may protect against recurrence of colorectal adenomas, which could lead to the subsequent prevention of cancer. Yet the trials used only a large single dose and were of small sizes, and thus, knowledge of the dose-response relationship and influence on h...

journal_title：International journal of cancer

authors： Keum N,Lee DH,Greenwood DC,Zhang X,Giovannucci EL

更新日期：2015-04-01 00:00:00

abstract：:Src has been one of the most studied proto-oncogenes. The cellular Src (c-Src) holds a critical role in several human malignancies and has emerged as a key factor that promotes tumor progression during the multistep process of colorectal cancer (CRC) pathogenesis. The robust activation of Src in CRC of aggressive phen...

journal_title：International journal of cancer

authors： Gargalionis AN,Karamouzis MV,Papavassiliou AG

更新日期：2014-05-01 00:00:00

abstract：:In mice as well as humans, cytotoxic T lymphocytes (CTL) specific for wild-type-sequence (wt) p53 peptides have been shown to react against a wide range of tumors, but not normal cells. As such, they are attractive candidates for developing broadly applicable cancer vaccines. Of particular interest is the potential of...

journal_title：International journal of cancer

authors： Cicinnati VR,Dworacki G,Albers A,Beckebaum S,Tüting T,Kaczmarek E,DeLeo AB

更新日期：2005-03-01 00:00:00

abstract：:In a cohort of 11,663 participants in a breast-cancer screening program, height, weight, waist circumference and hip circumference were measured, and information about menstrual and reproductive history was obtained by questionnaire. After exclusion of 83 women with unclear menopausal status, the subjects were divided...

journal_title：International journal of cancer

authors： Kaaks R,Van Noord PA,Den Tonkelaar I,Peeters PH,Riboli E,Grobbee DE

更新日期：1998-05-29 00:00:00

abstract：:Circadian disruption has been classified as probably carcinogenic to humans by the World Health Organization's International Agency for Research on Cancer. The circadian clock is subject to environmental factors, particularly light exposure and food intake rhythms. However, the association between nutritional circadia...

journal_title：International journal of cancer

authors： Srour B,Plancoulaine S,Andreeva VA,Fassier P,Julia C,Galan P,Hercberg S,Deschasaux M,Latino-Martel P,Touvier M

更新日期：2018-11-15 00:00:00

abstract：:The clinical pathological findings of eight cases of ovarian endodermal sinus tumour (yolk sac tumour) are presented. Histological exmination in all eight cases showed a typical endodermal sinus tumour pattern, and in six of the patients other tumour elements such as dysgerminoma, choriocarcinoma, malignant teratoma, ...

journal_title：International journal of cancer

authors： Sell A,Sogaard H,Norgaard-Pedersen B

更新日期：1976-11-15 00:00:00

abstract：:Detection of methylated free-circulating DNA (mfcDNA) for hyperplastic polyposis 1 (HPP1) in blood is correlated with a poor prognosis for patients with metastatic colorectal cancers (mCRC). Here, we analyzed the plasma levels of HPP1 mfcDNA in mCRC patients treated with a combination therapy containing a fluoropyrimi...

journal_title：International journal of cancer

authors： Herbst A,Vdovin N,Gacesa S,Ofner A,Philipp A,Nagel D,Holdt LM,Op den Winkel M,Heinemann V,Stieber P,Graeven U,Reinacher-Schick A,Arnold D,Ricard I,Mansmann U,Hegewisch-Becker S,Kolligs FT

更新日期：2017-05-01 00:00:00

abstract：:To understand specific interactions between stromal cells and epithelial cells in benign prostatic hyperplasia (BPH) and prostatic adenocarcinoma, we developed stromal-cell cultures from normal human prostate (PNX) and BPH (BH101), composed of fibroblasts and myofibroblasts. Their role in epithelial-cell growth was st...

journal_title：International journal of cancer

authors： Degeorges A,Tatoud R,Fauvel-Lafeve F,Podgorniak MP,Millot G,de Cremoux P,Calvo F

更新日期：1996-10-09 00:00:00

abstract：:A randomized screening trial was started in Europe to show the effect of early detection and treatment of prostate cancer on mortality (European Study on Screening of Prostate Cancer). In one centre (Rotterdam), the screening protocol initially consisted of 3 screening tests for all men: prostate-specific antigen (PSA...

journal_title：International journal of cancer

authors： Beemsterboer PM,Kranse R,de Koning HJ,Habbema JD,Schröder FH

更新日期：1999-08-20 00:00:00

abstract：:Intracellular thiols have been proposed as mediators of resistance to alkylating agents and cisplatin. As metallothionein is the predominant protein thiol, we examined its relationship to cisplatin resistance in human ovarian cancer cell lines. A human ovarian carcinoma cell line, A2780, derived from an untreated pati...

journal_title：International journal of cancer

authors： Schilder RJ,Hall L,Monks A,Handel LM,Fornace AJ Jr,Ozols RF,Fojo AT,Hamilton TC

更新日期：1990-03-15 00:00:00

abstract：:Extensive hypermethylation and consecutive transcriptional silencing of tumorsuppressor genes have been documented in multiple tumor entities including breast cancer. In a microarray based genome-wide methylation analysis of five sporadic breast carcinomas we identified a hypermethylated CpG island within the first in...

journal_title：International journal of cancer

authors： Versmold B,Felsberg J,Mikeska T,Ehrentraut D,Köhler J,Hampl JA,Röhn G,Niederacher D,Betz B,Hellmich M,Pietsch T,Schmutzler RK,Waha A

更新日期：2007-08-01 00:00:00

abstract：:TAAs of the MAGE family are mostly studied as targets of specific immune responses. Their potential relevance as tumor markers has also been underlined. We used a MAb, 57B, recognizing MAGE-A4 protein in paraffin-embedded sections, to evaluate its expression in bladder cancers by employing TMA including 2,317 samples ...

journal_title：International journal of cancer

authors： Kocher T,Zheng M,Bolli M,Simon R,Forster T,Schultz-Thater E,Remmel E,Noppen C,Schmid U,Ackermann D,Mihatsch MJ,Gasser T,Heberer M,Sauter G,Spagnoli GC

更新日期：2002-08-20 00:00:00

abstract：:Dietary factors in the aetiology of stomach cancer were investigated using data from a case-control study conducted in Northern Italy on 206 histologically confirmed carcinomas and 474 control subjects in hospital for acute, non-digestive conditions, unrelated to any of the potential risk factors for gastric cancer. D...

journal_title：International journal of cancer

authors： La Vecchia C,Negri E,Decarli A,D'Avanzo B,Franceschi S

更新日期：1987-10-15 00:00:00

abstract：:We have investigated the effect of pre-treatment with the anti-cancer drugs cisplatin and etoposide on the susceptibility of P815 murine mastocytoma cells to lysis by murine spleen-derived anti-CD3-activated killer-T (AK-T) cells. A 20 hr pre-treatment with cisplatin (0.2-2 microg/ml) or etoposide (0.01-1 microg/ml) r...

journal_title：International journal of cancer

authors： Williams BA,Makrigiannis AP,Blay J,Hoskin DW

更新日期：1997-11-04 00:00:00

abstract：:Many studies have focused on global hypomethylation or hypermethylation of tumor suppressor genes, but less is known about the impact of promoter hypomethylation of oncogenes. We previously showed that promoter methylation may gradually increase or decrease during the transition from gastric mucosa (GM) to intestinal ...

journal_title：International journal of cancer

authors： Seo EH,Kim HJ,Kim JH,Lim B,Park JL,Kim SY,Lee SI,Jeong HY,Song KS,Kim YS

更新日期：2020-06-15 00:00:00

abstract：:Angiogenesis in pancreatic ductal adenocarcinomas depends on the presence of angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) and is thought to be stimulated by hypoxia. We tested the angiogenic potential of 9 cell lines of pancreatic ductal carcinoma origi...

journal_title：International journal of cancer

authors： Sipos B,Weber D,Ungefroren H,Kalthoff H,Zühlsdorff A,Luther C,Török V,Klöppel G

更新日期：2002-12-20 00:00:00

abstract：:Normal thyroid epithelial cells lack major histocompatibility complex (MHC) Class II antigen. Oncogenic kinases involved in papillary thyroid carcinoma (PTC) trigger the expression of Class II transactivator and MHC Class II complex. However, the relationship between MHC Class II antigen expression and clinical outcom...

journal_title：International journal of cancer

authors： Jo YS,Lee JC,Li S,Choi YS,Bai YS,Kim YJ,Lee IS,Rha SY,Ro HK,Kim JM,Shong M

更新日期：2008-02-15 00:00:00

abstract：:Membrane-type metalloproteinase-1 (MT1-MMP) is a transmembrane metalloproteinase overexpressed in tumors, which plays a major role in the first step of pro-MMP-2 activation, leading to the generation of an intermediate 62 kDa species. The second step of MMP-2 activation that yields to the mature form is less understoo...

journal_title：International journal of cancer

authors： Sounni NE,Baramova EN,Munaut C,Maquoi E,Frankenne F,Foidart JM,Noël A

更新日期：2002-03-01 00:00:00