Treatment of intracranial human glioblastoma by direct intratumoral administration of 131I-labelled anti-tenascin monoclonal antibody BC-2.

abstract：:The human polyomaviruses JC virus (JCV) and BK virus (BKV) are oncogenic in experimental systems and commonly infect humans. JCV DNA has been reported to be present in human colon mucosa and in colorectal cancers. To investigate whether the risk for colorectal cancer is associated with JCV or BKV infection, we perform...

journal_title：International journal of cancer

authors： Lundstig A,Stattin P,Persson K,Sasnauskas K,Viscidi RP,Gislefoss RE,Dillner J

更新日期：2007-09-01 00:00:00

abstract：:To elucidate the individual impacts of insulin and blood glucose on cancer risk, we investigated the association of plasma C-peptide, a surrogated marker of insulin and glycated albumin (GA), a more stable marker of blood glucose, with all-site and site-specific cancer risk by mutually accounting for their confounding...

journal_title：International journal of cancer

authors： Hidaka A,Budhathoki S,Yamaji T,Sawada N,Tanaka-Mizuno S,Kuchiba A,Charvat H,Goto A,Shimazu T,Inoue M,Noda M,Tsugane S,Iwasaki M,JPHC Study Group.

更新日期：2019-02-15 00:00:00

abstract：:Adhesion molecules involved in attachment between human pancreatic carcinoma and activated endothelial cells in vitro were investigated. Basal adhesion occurred between 6 pancreatic carcinoma cell lines and unstimulated human umbilical vein endothelial cells (HUVEC), and augmented basal adhesion to activated HUVEC was...

journal_title：International journal of cancer

authors： Iwai K,Ishikura H,Kaji M,Sugiura H,Ishizu A,Takahashi C,Kato H,Tanabe T,Yoshiki T

更新日期：1993-07-30 00:00:00

abstract：:Carcinomatous meningitis is a devastating metastatic complication of systemic carcinoma, which may occur insidiously, accompanied by a confusing spectrum of clinical symptoms and signs. In the absence of reliable diagnostic tumour markers, the diagnosis is established by the demonstration of malignant cells within the...

journal_title：International journal of cancer

authors： Moseley RP,Oge K,Shafqat S,Moseley CM,Sullivan NM,Badley RA,Burchell J,Taylor-Papadimitriou J,Coakham HB

更新日期：1989-09-15 00:00:00

abstract：:In order to understand the expression and modulation of adhesion molecules (AMs) on the surface of different gastric cancers, we studied 4 gastric-cancer cell lines including SC-M1, KATO-III, AGS and AZ-521. The expression of E-cadherin, integrins (beta1, beta2 and beta3), ICAMs (1 and 2), and CD11 (a, b and c) on the...

journal_title：International journal of cancer

authors： Hsieh MC,Wu CW,Wu LH,Lui WY,P'eng FK,Yu CL

更新日期：1996-09-04 00:00:00

abstract：:Cell populations resistant to high doses (30 microM) of 6-thioguanine (6-TG, 6-TG(r) cells) were selected from a human colon carcinoma cell line, LoVo. This cell line, which lacks hMSH2, a component of the human mismatch binding heterodimer hMutSalpha, is resistant to low doses of 6-TG. The level of activity of hypoxa...

journal_title：International journal of cancer

authors： Bemi V,Turchi G,Margotti E,Giorgelli F,Pesi R,Sgarrella F,Tozzi MG,Camici M

更新日期：1999-08-12 00:00:00

abstract：:We have employed the DNA-mediated gene transfer method to introduce the allogenic major-histocompatibility-complex(MHC)-class-I gene H-2Kb into the K36.16 tumor cells, H-2k, in order to generate tumor-specific immunity. The acquisition of immunogenicity by the H-2Kb-transformed clones following gene transfer is associ...

journal_title：International journal of cancer

authors： Chia KY,Lim SP,Oei AA,Sabapathy TK,Hui KM

更新日期：1994-04-15 00:00:00

abstract：:The flavonoids, a group of more than 4,000 polyphenolic antioxidants, are potential cancer preventive components of fruits and vegetables. Catechins, one of the 6 major groups of flavonoids, are present in high concentrations in tea as well. Our objective was to evaluate the association between intake of catechins and...

journal_title：International journal of cancer

authors： Arts IC,Hollman PC,Bueno De Mesquita HB,Feskens EJ,Kromhout D

更新日期：2001-04-15 00:00:00

abstract：:Altered DNA methylation is often seen in malignant cells, potentially contributing to carcinogenesis by suppressing gene expression. We hypothesized that heritable methylation potential might be a risk factor for breast cancer and evaluated possible association with breast cancer for single nucleotide polymorphisms (S...

journal_title：International journal of cancer

authors： Harlid S,Ivarsson MI,Butt S,Hussain S,Grzybowska E,Eyfjörd JE,Lenner P,Försti A,Hemminki K,Manjer J,Dillner J,Carlson J

更新日期：2011-10-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer mortality in the world. Although exposure to carcinogens is considered to be the main cause, genetic variation may contribute to lung cancer risk. Murine double minute 2, MDM2, is a key regulator of p53 activity and recently a polymorphism in the promoter region of the MDM2 g...

journal_title：International journal of cancer

authors： Lind H,Zienolddiny S,Ekstrøm PO,Skaug V,Haugen A

更新日期：2006-08-01 00:00:00

abstract：:We have addressed the role of bacterial co-infection in viral oncogenesis using as model Epstein-Barr virus (EBV), a human herpesvirus that causes lymphoid malignancies and epithelial cancers. Infection of EBV carrying epithelial cells with the common oral pathogenic Gram-negative bacterium Aggregatibacter actinomycet...

journal_title：International journal of cancer

authors： Frisan T,Nagy N,Chioureas D,Terol M,Grasso F,Masucci MG

更新日期：2019-01-01 00:00:00

abstract：:Diabetes is a risk factor for many cancers; chronic hyperglycemia is hypothesized to be, in part, explanatory. We evaluated the association between glycated hemoglobin, a time-integrated glycemia measure, and cancer incidence and mortality in nondiabetic and diabetic men and women. We conducted a prospective study of ...

journal_title：International journal of cancer

authors： Joshu CE,Prizment AE,Dluzniewski PJ,Menke A,Folsom AR,Coresh J,Yeh HC,Brancati FL,Platz EA,Selvin E

更新日期：2012-10-01 00:00:00

abstract：:BALB/c peritoneal plasmacytomas induced by a variety of agents are invariably associated with a c-myc translocation. In contrast, naturally arising bone marrow plasma cell tumors in C57BL/KaLwRij mice lack this translocation. This difference has led to the suggestion that these are 2 fundamentally different plasma cel...

journal_title：International journal of cancer

authors： Pumphrey JG,Hausner P,Rudikoff S

更新日期：1997-09-04 00:00:00

abstract：:Somatic cell hybrids have been made between a transformed mouse bladder carcinoma cell line and normal mouse bladder epithelium and mesenchyme. In the epithelial tumour/mesenchyme hybrids the malignant phenotype was expressed dominantly whereas in the carcinoma/normal epithelium hybrids the malignant potential was gre...

journal_title：International journal of cancer

authors： Cowell JK,Franks LM

更新日期：1984-05-15 00:00:00

abstract：:Studies of the MLTI were performed in a primary MSV-induced tumor system. Reactivity against mitomycin-C-treated RBL-5 cells could be detected during a limited period at about 14 days after virus injection. The degree of reactivity of MSV 14 spleen cells was quite variable; stimulation indices ranged from 2.2 to 9.4. ...

journal_title：International journal of cancer

authors： Kirchner H,Glaser M,Holden HT,Herberman RB

更新日期：1976-03-15 00:00:00

abstract：:Osteosacarcoma (OS) lung metastases are often resistant to chemotherapy. Most anticancer drugs are administered systemically. In many cases this is followed by dose-dependent toxicity, which may not allow the achievement of therapeutic levels in lungs to eradicate metastases. We determined the efficacy of gemcitabine ...

journal_title：International journal of cancer

authors： Koshkina NV,Kleinerman ES

更新日期：2005-09-01 00:00:00

abstract：:A challenging task of the immune system is to fight cancer cells. However, a variety of human cancers educate immune cells to become tumor supportive. This is exemplified for tumor-associated macrophages (TAMs), which are polarized towards an anti-inflammatory and cancer promoting phenotype. Mechanistic explanations, ...

journal_title：International journal of cancer

authors： Weigert A,Schiffmann S,Sekar D,Ley S,Menrad H,Werno C,Grosch S,Geisslinger G,Brüne B

更新日期：2009-11-01 00:00:00

abstract：:Breast cancer (BC) and diabetes mellitus (DM) are major health problems. We examined the association between DM and BC stage at diagnosis and subsequent survival in a Finnish cohort of female BC patients. All BC cases (N = 73,170) diagnosed in 1995-2013 with dates and causes of death were identified from the Finnish C...

journal_title：International journal of cancer

authors： Murto MO,Artama M,Pukkala E,Visvanathan K,Murtola TJ

更新日期：2018-06-01 00:00:00

abstract：:Ocimum sp. is a traditionally used medicinal herb, which shows anti-oxidant, anti-carcinogenic, radio-protective and free radical scavenging properties. So far no detailed studies have been reported on its effects on human cancers. Thus, we analyzed its effects on human breast cancer utilizing in vitro and in vivo met...

journal_title：International journal of cancer

authors： Nangia-Makker P,Tait L,Shekhar MP,Palomino E,Hogan V,Piechocki MP,Funasaka T,Raz A

更新日期：2007-08-15 00:00:00

abstract：:Recent reports suggest that autoantibodies directed to aberrantly glycosylated mucins, in particular MUC1 and MUC4, are found in patients with colorectal cancer. There is, however, limited information on the autoantibody levels before clinical diagnosis, and their utility in cancer screening in the general population....

journal_title：International journal of cancer

authors： Pedersen JW,Gentry-Maharaj A,Nøstdal A,Fourkala EO,Dawnay A,Burnell M,Zaikin A,Burchell J,Papadimitriou JT,Clausen H,Jacobs I,Menon U,Wandall HH

更新日期：2014-05-01 00:00:00

abstract：:To understand specific interactions between stromal cells and epithelial cells in benign prostatic hyperplasia (BPH) and prostatic adenocarcinoma, we developed stromal-cell cultures from normal human prostate (PNX) and BPH (BH101), composed of fibroblasts and myofibroblasts. Their role in epithelial-cell growth was st...

journal_title：International journal of cancer

authors： Degeorges A,Tatoud R,Fauvel-Lafeve F,Podgorniak MP,Millot G,de Cremoux P,Calvo F

更新日期：1996-10-09 00:00:00

abstract：:The open reading frames of the phosphoprotein pp58 (BMRFI) and the deoxyribonuclease (BGLF5) of the Epstein-Barr-virus (EBV) strain M-ABA were cloned in the baculovirus expression vectors pAc373 and pAc360 and expressed in the Spodoptera frugiperda (SF158) insect cells. The recombinant phosphoprotein pp58 expressed in...

journal_title：International journal of cancer

authors： Chen HF,Sauter M,Haiss P,Müller-Lantzsch N

更新日期：1991-07-30 00:00:00

abstract：:We have shown that the loss of p53 function contributed to resistance of tumor cells to TNF-induced cytotoxicity. In the present study, we evaluated the effect of wild-type p53 (wt-p53) expression on TNF sensitivity, by introducing wt-p53 into MCF7/Adr cells in which p53 was deleted, via a recombinant adenovirus encod...

journal_title：International journal of cancer

authors： Shatrov VA,Ameyar M,Bouquet C,Cai Z,Stancou R,Haddada H,Chouaib S

更新日期：2000-01-01 00:00:00

abstract：:Epidemiologic evidence is lacking for the association between alcohol consumption and the risk of breast cancer in Japanese women. We addressed this association in a prospective cohort study with an average follow-up of 7.6 years. At baseline (1988-1990), cohort participants completed a self-administered questionnaire...

journal_title：International journal of cancer

authors： Lin Y,Kikuchi S,Tamakoshi K,Wakai K,Kondo T,Niwa Y,Yatsuya H,Nishio K,Suzuki S,Tokudome S,Yamamoto A,Toyoshima H,Tamakoshi A

更新日期：2005-09-20 00:00:00

abstract：:We have examined the effect of various cell monolayers on the ability of mouse spleen cells to lyse tumor cell targets (natural cytotoxicity reaction). Natural killer (NK) cell activity was reduced by as much as 75% depending on the cell substrate, with the greatest protection afforded by endothelial cells. Cell adhes...

journal_title：International journal of cancer

authors： Kaminski M,Auerbach R

更新日期：1988-06-15 00:00:00

abstract：:The WHO Classification of Tumours provides the international standards for the classification and diagnosis of tumours. It enables direct comparisons to be made between different countries. In the new fifth edition, the series has gone digital with the launch of a website as well as a series of books, known widely as ...

journal_title：International journal of cancer

authors： Washington MK,Goldberg RM,Chang GJ,Limburg P,Lam AK,Salto-Tellez M,Arends MJ,Nagtegaal ID,Klimstra DS,Rugge M,Schirmacher P,Lazar AJ,Odze RD,Carneiro F,Fukayama M,Cree IA,WHO Classification of Tumours Editorial Board.

更新日期：2021-03-01 00:00:00

abstract：:We describe the selection of 3 new multidrug-resistant cell lines derived from tumor cells of different metastatic phenotypes within the Dunning R3327 model of rat prostatic carcinoma. Cell lines of weak (AT2) and strong (AT3 and MAT-LyLu) metastatic behavior were cultured in vitro and challenged with doxorubicin at p...

journal_title：International journal of cancer

authors： Bashir I,Sikora K,Abel P,Foster CS

更新日期：1994-06-01 00:00:00

abstract：:The CpG island methylator phenotype (CIMP) is a distinct form of epigenomic instability. Many CIMP-high colorectal cancers (CRCs) with BRAF mutation are considered to arise from serrated pathway. We recently reported that microRNA-31 (miR-31) is associated with BRAF mutation in colorectal tumors. Emerging new approach...

journal_title：International journal of cancer

authors： Ito M,Mitsuhashi K,Igarashi H,Nosho K,Naito T,Yoshii S,Takahashi H,Fujita M,Sukawa Y,Yamamoto E,Takahashi T,Adachi Y,Nojima M,Sasaki Y,Tokino T,Baba Y,Maruyama R,Suzuki H,Imai K,Yamamoto H,Shinomura Y

更新日期：2014-12-01 00:00:00

abstract：:The impact of the organised cervical cancer (CC) screening programmes implemented in Europe since the 1990s has been insufficiently evaluated. We investigated the changes in CC incidence following the introduction of a screening programme in the Emilia-Romagna Region (northern Italy). The study period was 1988-2013. T...

journal_title：International journal of cancer

authors： Bucchi L,Baldacchini F,Mancini S,Ravaioli A,Giuliani O,Vattiato R,Falcini F,Giorgi Rossi P,Campari C,Canuti D,Di Felice E,Sassoli de Bianchi P,Ferretti S,Bertozzi N,Biggeri A,Emilia-Romagna Region Workgroup for Cervical Scr

更新日期：2019-03-01 00:00:00

abstract：:Understanding the role of signal transduction in regulating pathways responsible for cell growth, survival and apoptosis is critical for cancer therapy. We developed and characterized a HER2/neu and Fas overexpressing cell line (BNT.888 ACA2) from a salivary gland adenocarcinoma that arose in a HER2/neu transgenic mou...

journal_title：International journal of cancer

authors： Piechocki MP,Yoo GH,Dibbley SK,Amjad EH,Lonardo F

更新日期：2006-07-15 00:00:00