Abstract：
:Delayed hypersensitivity reactions and antibody-mediated reactions to the carrier and to the hapten have been studied in animals treated with BCG or/and trypan blue before immunization with a hapten-carrier complex. The results show that it is possible to induce, with BCG, at the beginning of the response, an antigenic competition between hapten and carrier moieties of the antigen molecule. Macrophages which modulate the response to the hapten-carrier complex by acting both on T cells involved in cellular immunity and those involved in antibody synthesis, appear to be the target of antigenic competition.
journal_name
Immunologyjournal_title
Immunologyauthors
Neveu PJsubject
Has Abstractpub_date
1977-08-01 00:00:00pages
269-73issue
2eissn
0019-2805issn
1365-2567journal_volume
33pub_type
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