Nuclear pseudoinclusions in melanocytic naevi and melanomas.

abstract：:Of the 123 patients with acute mesenteric infarction treated over the past 12 years, 16 (13%) had mesenteric venous thrombosis. Eight of the patients with mesenteric venous thrombosis survived the initial episode; two have since died. The remaining six patients were studied for evidence of haemostatic deficiencies or ...

journal_title：Journal of clinical pathology

authors： Wilson C,Walker ID,Davidson JF,Imrie CW

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Currently, no specific immunohistochemical markers are available to differentiate primary mucinous epithelial ovarian cancer (MOC) from adenocarcinomas originating at other sites that have metastasised to the ovary, which may have an impact on patient management and prognosis. AIM:To investigate the express...

journal_title：Journal of clinical pathology

authors： Heinzelmann-Schwarz VA,Scolyer RA,Scurry JP,Smith AN,Gardiner-Garden M,Biankin AV,Baron-Hay S,Scott C,Ward RL,Fink D,Hacker NF,Sutherland RL,O'Brien PM

更新日期：2007-06-01 00:00:00

abstract：:Twenty five specimens of branchial cyst from the same number of patients have been examined. On staining with haematoxylin and eosin a consistent finding was that the mural lymphoid follicles were always aligned with their mantle zones towards the luminal epithelium. With conventional staining lymphatic sinuses were n...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R

更新日期：1985-07-01 00:00:00

abstract：:Prostaglandin E(2) (PGE(2)) was infused intravenously to eight women for the termination of pregnancy and tests of platelet function: coagulation and fibrinolysis were studied before and during the infusion.Platelet adhesiveness, as measured by a cellophane membrane test-cell system, was significantly diminished by PG...

journal_title：Journal of clinical pathology

authors： Howie PW,Calder AA,Forbes CD,Prentice CR

更新日期：1973-05-01 00:00:00

abstract：AIM:To identify and review cases of false negative needle core biopsy (NCB) in the preoperative investigation of radial scar/complex sclerosing lesion (RS/CSL) lesions - that is, benign NCB from RS/CSL which contained malignancy on excision. METHODS AND RESULTS:A total of 11 false negative NCB in RS/CSL lesions from 2...

journal_title：Journal of clinical pathology

authors： Douglas-Jones AG,Denson JL,Cox AC,Harries IB,Stevens G

更新日期：2007-03-01 00:00:00

abstract：:Visual differential counts were examined for efficiency, cost effectiveness, and staff acceptability within our laboratory. A comparison with the Hemalog D system was attempted. The advantages and disadvantages of each system are enumerated and discussed in the context of a large general hospital. ...

journal_title：Journal of clinical pathology

authors： Hudson MJ,Green AE

更新日期：1980-11-01 00:00:00

abstract：:Serum haptoglobin levels have been studied in patients with a number of haemolytic disorders. In general, serum haptoglobins were low in patients with increased haemolysis. Values were reduced irrespective of whether haemolysis occurred intravascularly or extravascularly. The reduction was related to the amount of hae...

journal_title：Journal of clinical pathology

authors： Owen JA,de Gruchy GC,Smith H

更新日期：1960-11-01 00:00:00

abstract：:The material from a case of Tietze's disease has been examined histologically. A review of the literature on the pathology of this lesion correlated with the findings from this case indicates that there is a pathological lesion in the costal cartilage in this disease. This consists of an increased vascularity and dege...

journal_title：Journal of clinical pathology

authors： Cameron HU,Fornasier VL

更新日期：1974-12-01 00:00:00

abstract：:Nasal biopsy findings in malignant histiocytosis presenting clinically as lethal midline granuloma are characterised by necrosis and infiltration of atypical histiocytic cells with a diffuse positive reaction for non-specific esterase. This cellular character was common to midline malignant reticulosis, and midline ma...

journal_title：Journal of clinical pathology

authors： Aozasa K

更新日期：1982-06-01 00:00:00

abstract：:Fluorigenic substrates prepared from 4-methylumbelliferone provide a simple, convenient method for detecting and assaying group-specific hydrolase activity in small quantities of whole mycobacteria. Physico-chemical properties of the enzymes such as pH dependence and heat stability may also be studied. A technique is ...

journal_title：Journal of clinical pathology

authors： Grange JM

更新日期：1978-04-01 00:00:00

abstract：AIMS:To determine the clinical performance of three cerebrospinal fluid (CSF) IgG synthesis formulae using data obtained from two quantitation methods. METHODS:Receiver operator characteristic (ROC) analysis and decision index plots were used to compare a rate nephelometric (RN) and a rocket immunoelectrophoretic (RIE...

journal_title：Journal of clinical pathology

authors： McMillan SA,Douglas JP,Droogan AG,Hawkins SA

更新日期：1996-01-01 00:00:00

abstract：:Protein HC and protein HC-IgA complex were measured in 18 different types of fluid sample from healthy subjects and patients with different illnesses to determine if the concentrations of protein HC and protein HC-IgA complexes could be used to monitor certain diseases, when measured separately. The normal values for ...

journal_title：Journal of clinical pathology

authors： Fernández-Luna JL,Leyva-Cobián F,Méndez E

更新日期：1988-11-01 00:00:00

abstract：:By means of enzyme immunoassays based on two monoclonal antibodies with specificities for distinct forms of placental type alkaline phosphatase (Pl-ALP), together with L-leucine inhibition studies, it has been possible to distinguish the Nagao type carcinoplacental enzyme from other placental type alkaline phosphatase...

journal_title：Journal of clinical pathology

authors： McLaughlin PJ,Twist AM,Evans CC,Johnson PM

更新日期：1984-07-01 00:00:00

abstract：:An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at al...

journal_title：Journal of clinical pathology

authors： Tapper-Jones L,Aldred M,Walker DM

更新日期：1980-03-01 00:00:00

abstract：:Two diabetic patients with symptomatic urinary tract infection by Torulopsis glabrata were successfully treated with two-week courses of 5-fluorocytosine. ...

journal_title：Journal of clinical pathology

authors： Speller DC

更新日期：1974-01-01 00:00:00

abstract：BACKGROUND:Serine peptidase inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, has well established associations with inflammation, cancer cell proliferation and carcinogenesis. However, the role of SPINK1 has not been investigated in stage IV colorectal cancer (CRC) patients receiving cetuximab based targete...

journal_title：Journal of clinical pathology

authors： Chen YT,Tsao SC,Tsai HP,Wang JY,Chai CY

更新日期：2016-04-22 00:00:00

abstract：:A 35 year old man with a fatal Campylobacter jejuni infection is described. He had HbE/beta zero thalassaemia and had undergone splenectomy nine months previously for hypersplenism; he also had chronic hepatitis C infection. He presented with high grade fever but no gastrointestinal symptoms and rapidly progressed to ...

journal_title：Journal of clinical pathology

authors： Jackson N,Zaki M,Rahman AR,Nazim M,Win MN,Osman S

更新日期：1997-05-01 00:00:00

abstract：:Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...

journal_title：Journal of clinical pathology

authors： Booth SN,Lakin G,Dykes PW,Burnett D,Bradwell AR

更新日期：1977-06-01 00:00:00

abstract：AIMS:To detect cells bearing BRAF mutations in colorectal tumour samples and peritoneal washings, using a mismatch ligation assay (MLA). METHODS:DNA from 46 colorectal tumours was studied. Part of exon 15 of the BRAF gene was amplified using the polymerase chain reaction, and T-->A mutations at codon 600 were detected...

journal_title：Journal of clinical pathology

authors： Busby K,Morris A

更新日期：2005-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) replication is reported in both tumour and non-tumour tissue in a case of hepatocellular carcinoma. Viral replication was established by showing the presence of minus strand HCV RNA by PCR amplification, after excluding residual reverse transcriptase activity of Taq polymerase. No minus strand ...

journal_title：Journal of clinical pathology

authors： Niu J,Kumar U,Monjardino J,Goldin R,Rosin D,Thomas HC

更新日期：1995-09-01 00:00:00

abstract：:Agar gel, cellulose acetate, and starch gel electrophoresis are all capable of diagnosing sickle-cell anaemia, sickle-cell haemoglobin C disease, and haemoglobin C disease in cord blood samples. Of these three electrophoretic techniques, agar gel is the easiest to interpret.Paper electrophoresis can reliably and rapid...

journal_title：Journal of clinical pathology

authors： Yaswon GI,Huntsman RG,Metters JS

更新日期：1970-09-01 00:00:00

abstract：AIMS:As part of the UK antimicrobial resistance strategy and action plan, the Public Health Laboratory Service (PHLS) is required to collect antibiotic susceptibility data so that resistance trends and patterns can be monitored. Most laboratories report urine Gram negative isolates, as "coliforms" according to morpholo...

journal_title：Journal of clinical pathology

authors： Fallon D,Andrews N,Frodsham D,Gee B,Howe S,Iliffe A,Nye KJ,Warren RE

更新日期：2002-07-01 00:00:00

abstract：:A series of 44 spleens removed from patients with Hodgkin's disease before treatment has been reviewed. The difficulties encountered in detecting foci of Hodgkin's tissue and the histological features and characteristics of early invasion are described. ...

journal_title：Journal of clinical pathology

authors： Farrer-Brown G,Bennett MH,Harrison CV,Millett Y,Jelliffe AM

更新日期：1972-04-01 00:00:00

abstract：AIMS:To determine the value of squamous mucosal histology in the assessment of patients with gastro-oesophageal reflux symptoms. METHODS:Sixty six patients with reflux symptoms underwent endoscopy with oesophageal biopsy, manometry, and 24 hour oesophageal pH testing. The following histological features were assessed ...

journal_title：Journal of clinical pathology

authors： Bowrey DJ,Williams GT,Clark GW

更新日期：2003-03-01 00:00:00

abstract：:The Royal College of Pathologists (RCPath) and College of American Pathologists recommend that at least 12 lymph nodes should be harvested for adequate staging of colorectal carcinoma. Just one nodal tumour deposit upstages the malignancy from pN0 to pN1. This is critically important as node-positive patients (pN1) ar...

journal_title：Journal of clinical pathology

authors： Horne J,Bateman AC,Carr NJ,Ryder I

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:Intraduct papillary mucinous neoplasm (IPMN) is a pancreatic tumour that is often associated with chronic pancreatitis (CP) in the surrounding pancreas. Type 1 autoimmune pancreatitis (AIP) is a fibro-inflammatory condition with characteristic histological features and prominent IgG4+ plasma cells and is par...

journal_title：Journal of clinical pathology

authors： Bateman AC,Culver EL,Sommerlad M,Chetty R

更新日期：2013-08-01 00:00:00

abstract：:Visceral candidiasis in 56 patients, 39 of whom were thought to be immune deficient, was investigated using three serological detection methods--whole cell agglutination, haemagglutination, and counterimmunoelectrophoresis for antibodies; two determinations of circulating antigens--haemagglutination inhibition and lat...

journal_title：Journal of clinical pathology

authors： Platenkamp GJ,Van Duin AM,Porsius JC,Schouten HJ,Zondervan PE,Michel MF

更新日期：1987-10-01 00:00:00

abstract：:Acute myocardial disease, which may be associated with abnormal platelet activity, has been reported after routine immunisation. Thirty-two army apprentices undergoing immunisation were studied for changes in the heparin neutralising activity (HNA) of platelet poor plasma. HNA increased after immunisation. This increa...

journal_title：Journal of clinical pathology

authors： Baker IA,Howells CH,O'Brien JR

更新日期：1979-11-01 00:00:00

abstract：:A recently developed procedure, that has been shown to be suitable for detailed immunohistological analysis, has been used to prepare cryostat sections of bone marrow to investigate whether enzyme-histochemical techniques are also feasible on such material. A selected group of enzymes, some of which are inhibited or d...

journal_title：Journal of clinical pathology

authors： Chilosi M,Pizzolo G,Janossy G,Bofill M,Fiore-Donati L

更新日期：1982-11-01 00:00:00

abstract：:The changes occurring at the periphery of invasive cervical carcinomas have been studied in detail, with particular reference to the incidence of preinvasive carcinoma. The various criteria used in the cytological diagnosis of malignancy have been evaluated, and the implications of large cytological screening programm...

journal_title：Journal of clinical pathology

authors： MEYER PC

更新日期：1965-07-01 00:00:00