Lymph node revealing solutions in colorectal cancer: should they be used routinely?

abstract：:Liver function was assessed in 38 Edinburgh haemophiliacs. Results before the introduction of NHS intermediate factor VIII concentrate from 1974 onwards were compared with values in 1979. Measurements of serum bile salts in 16 patients as well as conventional liver function tests gave useful evidence of deranged liver...

journal_title：Journal of clinical pathology

authors： Stirling ML,Beckett GJ,Percy-Robb IW

更新日期：1981-01-01 00:00:00

abstract：AIMS:To determine important factors influencing recurrence after local excision of duct carcinoma in situ (DCIS) of the breast. MATERIALS AND METHODS:The extent (size) in millimetres, classification (by cytonuclear grade (NHSBSP system), by extent of necrosis, and by the Van Nuys system), and excision margins of 115 c...

journal_title：Journal of clinical pathology

authors： Douglas-Jones AG,Logan J,Morgan JM,Johnson R,Williams R

更新日期：2002-08-01 00:00:00

abstract：:Several studies have recently documented the presence of persistently abnormal liver function tests in asymptomatic haemophiliacs. While the aetiology is unknown it is possible that repeated exposure to agents transmitted in blood products may be important. This study has attempted to determine the prevalence of viral...

journal_title：Journal of clinical pathology

authors： McVerry BA,Ross MG,Knowles WA,Voke J

更新日期：1979-04-01 00:00:00

abstract：:Performance of CHROMagar Acinetobacter was assessed for the selective isolation and identification of Acinetobacter baumannii. The medium was effective in suppressing the growth of other Gram-positive and Gram-negative species while the addition of KPC supplement ensured growth of only carbapenem resistant A baumannii...

journal_title：Journal of clinical pathology

authors： Wareham DW,Gordon NC

更新日期：2011-02-01 00:00:00

abstract：:The laboratory findings in seven cases of endocarditis caused by coagulase-negative staphylococci are presented. The usefulness of biochemical characterization of the strains in diagnosis and the selection of antibiotics for prophylaxis and treatment are discussed. ...

journal_title：Journal of clinical pathology

authors： Speller DC,Mitchell RG

更新日期：1973-07-01 00:00:00

abstract：:In a study of a group of 325 blood donors between the ages of 18 and 65 years, the total leucocyte and polymorph counts of the females aged 50 to 65 years were found to be significantly lower than those of the corresponding group of male donors. In the whole series of female donors, there were significantly lower tota...

journal_title：Journal of clinical pathology

authors： Allan RN,Alexander MK

更新日期：1968-11-01 00:00:00

abstract：:Circulating immune complexes have been detected in the sera of 24 Nigerian children with acute poststreptococcal glomerulonephritis using two methods. There was a significant correlation between levels of soluble complexes, detected in samples taken from patients in the oliguric phase of acute nephritis, and severity ...

journal_title：Journal of clinical pathology

authors： Onyewotu II,Mee J

更新日期：1978-09-01 00:00:00

abstract：:A simple laboratory method for culture of continuous ambulatory peritoneal dialysis (CAPD) fluids is described. Guidelines for antimicrobial therapy are discussed based on results from 18 patients studied over an 11-week period. Cephalosporins appeared to be a rational choice for therapy while awaiting laboratory resu...

journal_title：Journal of clinical pathology

authors： Fenton P

更新日期：1982-11-01 00:00:00

abstract：:Thirty two fire victims with smoke inhalation, with or without burns, and 26 control subjects had bronchoalveolar lavage performed. Cell yields and differential cell counts were assessed. All patients and controls were cigarette smokers. Patients with smoke inhalation (SI) injury generally showed higher total bronchoa...

journal_title：Journal of clinical pathology

authors： Riyami BM,Tree R,Kinsella J,Clark CJ,Reid WH,Campbell D,Gemmell CG

更新日期：1990-01-01 00:00:00

abstract：:An immunochemical procedure for routine laboratory diagnosis of pregnancy utilizing adsorption of human chorionic gonadotrophin onto kaolin and the Ortho pregnancy test reagents is described. The method is suitable for quantitative assay of urinary human chorionic gonadotrophin and can be adapted for use with serum. I...

journal_title：Journal of clinical pathology

authors： ORBAN TD

更新日期：1964-09-01 00:00:00

abstract：:The development and evaluation of a new selective medium for Streptococcus pneumoniae is described. It is shown that the new medium (crystal violet-nalidixic acid-gentamicin agar:CVNG) is highly selective for Strep. pneumoniae in sputum specimens containing other organisms and is also sensitive, being only marginally ...

journal_title：Journal of clinical pathology

authors： Nichols T,Freeman R

更新日期：1980-08-01 00:00:00

abstract：AIMS:To assess the occurrence of diagnostic delay in primary antibody deficiency in the period 1989-2002, since a similar study in 1989, and to assess the impact of UK national guidelines communicated in 1995. METHODS:A retrospective case note review was performed of 89 consecutive patients with antibody deficiency re...

journal_title：Journal of clinical pathology

authors： Seymour B,Miles J,Haeney M

更新日期：2005-05-01 00:00:00

abstract：:Serum glycocholic acid (SGC) was measured by radioimmunoassay in 277 samples from 122 children with hepatobiliary disorders and from 23 healthy age-matched controls. In patients with hepatobiliary disease the SGC was more frequently abnormal (83%) than values for serum albumin (7%), prothrombin time (17%), bilirubin (...

journal_title：Journal of clinical pathology

authors： Matsui A,Psacharopoulos HT,Mowat AP,Portmann B,Murphy GM

更新日期：1982-09-01 00:00:00

abstract：:The effect of radiotherapy on normal buccal mucosa was investigated using the quantitative techniques of cytomorphology (measurement of nuclear and cytoplasmic area) and DNA cytophotometry. These techniques were applied to smears obtained before, during, and after irradiation. Nuclear area and cytoplasmic area increas...

journal_title：Journal of clinical pathology

authors： Ogden GR,Cowpe JG,Green MW

更新日期：1989-09-01 00:00:00

abstract：AIMS:To investigate the expression of the placental cell-specific associated proteins in infantile haemangioma (IH). METHODS:Immunohistochemical staining was used to investigate the expression of human chorionic gonadotrophin (hCG), human placental lactogen (hPL), human leucocyte antigen-G (HLA-G), cytokeratin 7 (CK7)...

journal_title：Journal of clinical pathology

authors： Itinteang T,Tan ST,Guthrie S,Tan CE,McIntyre BC,Brasch HD,Day DJ

更新日期：2011-10-01 00:00:00

abstract：:Two examples of intraplacental choriocarcinoma are described. Both were small and had arisen in otherwise normal third trimester placentas. The covering mantle of many of the villi adjacent to the choriocarcinomas was formed, either focally or wholly, of neoplastic trophoblastic tissue: it is only at this stage of the...

journal_title：Journal of clinical pathology

authors： Fox H,Laurini RN

更新日期：1988-10-01 00:00:00

abstract：AIMS:To describe characteristics of a series of people accidentally and deliberately killed by air powered weapons. METHODS:Five cases of fatal airgun injury were identified by forensic pathologists and histopathologists. The circumstances surrounding the case, radiological examination, and pathological findings are d...

journal_title：Journal of clinical pathology

authors： Milroy CM,Clark JC,Carter N,Rutty G,Rooney N

更新日期：1998-07-01 00:00:00

abstract：AIMS:To evaluate the prognostic impact of the width of negative surgical margins (NSM) and associated and preinvasive lesions at the NSM in patients with penile squamous cell cancer (PSC). METHODS:Enrolling 87 patients with NSM who underwent surgery for PSC, the archived margin slides and entirely wax-embedded surgica...

journal_title：Journal of clinical pathology

authors： Gunia S,Koch S,Jain A,May M

更新日期：2014-03-01 00:00:00

abstract：AIMS:Glypican 3 (GPC3) is a heparan sulphate proteoglycan that shows elevated levels in the serum of patients with hepatocellular carcinoma (HCC), but not in healthy blood donors or patients with benign liver disease. This study explores the value of GPC3 expression for diagnosis of HCC by immunohistochemistry in liver...

journal_title：Journal of clinical pathology

authors： Wang FH,Yip YC,Zhang M,Vong HT,Chan KI,Wai KC,Wen JM

更新日期：2010-07-01 00:00:00

abstract：:This paper records the results of the intravenous inoculation of chick embryos with type 5 gonococci and establishes that these strains are pathogenic. ...

journal_title：Journal of clinical pathology

authors： Hafiz S,Jennings R,McEntegart MG,Jephcott AE

更新日期：1978-05-01 00:00:00

abstract：:In studies using indirect immunofluorescence IgG antibodies to Clostridium perfringens were found in sera from healthy adults. Sera from 236 healthy children were examined. The normally occurring IgG antibodies to C perfringens were found to have an age related variation. Preliminary data suggest that they are not cor...

journal_title：Journal of clinical pathology

authors： Zarén E,Schwan A,Frenckner B

更新日期：1987-03-01 00:00:00

abstract：:Transmembrane serine protease 2 is encoded by the TMPRSS2 gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the inactive zymogen form. A fusion gene between the TMPRSS2 gene and ERG (erythroblast-specific-related gene), an oncogenic transcription factor, is the most c...

journal_title：Journal of clinical pathology

authors： Thunders M,Delahunt B

更新日期：2020-12-01 00:00:00

abstract：AIMS:The perforin mediated pathway is the major pathway of cytotoxicity induced by activated T cells and natural killer cells, and may be involved in the development of pulmonary fibrosis. METHODS:Perforin and granzyme B expression were examined in idiopathic pulmonary fibrosis by means of immunohistochemistry, and pe...

journal_title：Journal of clinical pathology

authors： Miyazaki H,Kuwano K,Yoshida K,Maeyama T,Yoshimi M,Fujita M,Hagimoto N,Yoshida R,Nakanishi Y

更新日期：2004-12-01 00:00:00

abstract：:Apocrine morphology is a common phenomenon encountered in everyday breast pathology practice, and is defined as cuboidal or columnar cells exhibiting abundant eosinophilic granular cytoplasm, prominent apical granules, a low nuclear-cytoplasmic ratio, and round nuclei with pale chromatin and prominent nucleoli. Apocri...

journal_title：Journal of clinical pathology

authors： D'Arcy C,Quinn C

更新日期：2019-01-01 00:00:00

abstract：:In this necropsy review of 37 cases of acute pancreatitis, evidence is presented that there are at least two different initiating mechanisms in acute necrotising pancreatitis in man. Firstly, there is primary duct inflammation, with subsequent inflammation and necrosis of the pancreatic parenchyma surrounding the excr...

journal_title：Journal of clinical pathology

authors： Foulis AK

更新日期：1980-12-01 00:00:00

abstract：:TLE 1 is the human homologue belonging to a family of four genes and is located on chromosome 9q21. It consists of 19 exons. Although it does not bind directly to DNA, it acts as a repressor of several signalling pathways via transcription factors. TLE1 protein has several physiological roles in embryogenesis, haemato...

journal_title：Journal of clinical pathology

authors： Pinto K,Chetty R

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Currently, no specific immunohistochemical markers are available to differentiate primary mucinous epithelial ovarian cancer (MOC) from adenocarcinomas originating at other sites that have metastasised to the ovary, which may have an impact on patient management and prognosis. AIM:To investigate the express...

journal_title：Journal of clinical pathology

authors： Heinzelmann-Schwarz VA,Scolyer RA,Scurry JP,Smith AN,Gardiner-Garden M,Biankin AV,Baron-Hay S,Scott C,Ward RL,Fink D,Hacker NF,Sutherland RL,O'Brien PM

更新日期：2007-06-01 00:00:00

abstract：:Sodium-alpha-naphthylamine-4-sulphonate (Naphthionin) appears to shorten the bleeding time in normal subjects and to be of value in the management of the bleeding defect in patients with thrombocytopenia when given by intravenous or intramuscular injection. A good response was achieved in three patients suffering from...

journal_title：Journal of clinical pathology

authors： POLLER L,MORE JR

更新日期：1964-11-01 00:00:00

abstract：:The only method currently available to perform Neisseria gonorrhoeae antimicrobial susceptibility testing (Ng-AST) requires a viable organism obtained by culture. Reports of in vitro resistance to extended-spectrum cephalosporins, the treatment of choice for gonorrhoea, coupled with increasing gonorrhoea diagnoses is ...

journal_title：Journal of clinical pathology

authors： Jain A,Cole MJ,Planche T,Ison CA

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:Cutaneous squamous cell carcinoma (cSCC) is the second most common malignancy, most frequently affecting the head and neck. Treatment often requires surgery and can have significant functional morbidity. Research into disease pathogenesis and second line medical management of cSCC is limited. We assess geneti...

journal_title：Journal of clinical pathology

authors： Zilberg C,Lee MW,Kraitsek S,Ashford B,Ranson M,Shannon K,Iyer NG,Ch'ng S,Low TH,Palme C,Clark J,Gupta R,Yu B

更新日期：2020-01-01 00:00:00