Gene of the month: TLE 1.

abstract：:The morphological classification and diagnosis of bladder neoplasms is summarised, with specific focus on histological typing, grading and staging. Four diagnostic categories are described on the basis of the pattern of growth of the urothelial lesions and tumours (flat, exophytic or papillary, endophytic, and invasiv...

journal_title：Journal of clinical pathology

authors： Montironi R,Mazzucchelli R,Scarpelli M,Lopez-Beltran A,Cheng L

更新日期：2008-01-01 00:00:00

abstract：:Severe osteomalacia (confirmed by the examination of thin undecalcified bone biopsy sections) associated with hypophosphataemia developed in a 60 year old woman. A skeletal x-ray survey showed a lytic lesion in the right proximal femur, and this was curetted, showing a vascular tumour. The patient's symptoms improved ...

journal_title：Journal of clinical pathology

authors： McClure J,Smith PS

更新日期：1987-04-01 00:00:00

abstract：:Lymphocyte-depleted classical Hodgkin lymphoma (LDCHL) is the rarest entity among the classical Hodgkin lymphoma (CHL) subtypes, accounting for <1% of CHL cases in Western countries. Similarly, primary splenic Hodgkin lymphoma is a rare diagnosis among all cases of lymphomatous involvement of spleen. Representing a co...

journal_title：Journal of clinical pathology

authors： Parekh V,Peker D

更新日期：2015-11-01 00:00:00

abstract：:A case is reported of a patient with plasmacytoma which assumed different clinicopathological features over seven years. The tumour first presented as a subcutaneous mass which was misdiagnosed as anaplastic carcinoma. Complete response to radiotherapy ensued but recurrence took the form of an intracerebral tumour. Fu...

journal_title：Journal of clinical pathology

authors： Kwong YL,Ng WK

更新日期：1994-10-01 00:00:00

abstract：:Histological examination of the lower margin of the internal sphincter has demonstrated an increased amount of fibrous tissue in patients with haemorrhoids compared with controls. This finding may be of relevance to the treatment of haemorrhoids by maximal anal dilatation. ...

journal_title：Journal of clinical pathology

authors： Haqqani MT,Hancock BD

更新日期：1978-03-01 00:00:00

abstract：AIMS:Common variable immunodeficiency (CVID) is the most common serious primary immunodeficiency. This paper describes the immunological consequences of human immunodeficiency virus (HIV) infection in a patient with familial CVID subsequently treated with highly active antiretroviral therapy (HAART). METHODS:Serial me...

journal_title：Journal of clinical pathology

authors： Jolles S,Tyrer M,Johnson M,Webster D

更新日期：2001-09-01 00:00:00

abstract：:Chromosome studies were attempted on 97% of necropsies carried out in the Department of Histopathology of the Adelaide Children's Hospital over the four-year period ending May 1981. Results were obtained from 89% of necropsies of which 7.5% had major chromosome abnormalities. The chromosome results are analysed accord...

journal_title：Journal of clinical pathology

authors： Sutherland GR,Carter RF

更新日期：1983-02-01 00:00:00

abstract：AIMS:To determine the prognostic usefulness of the Nottingham histological grade (NHG) and its components in a series of 270 patients with stage pT1N0M0 breast cancer with a median follow up of 12.5 years. METHODS:Microscopic slides were re-examined and the degree of tubule formation, nuclear pleomorphism, and mitotic...

journal_title：Journal of clinical pathology

authors： Frkovic-Grazio S,Bracko M

更新日期：2002-02-01 00:00:00

abstract：:Cervical smears from 327 women were examined using the polymerase chain reaction (PCR) targeted to a sequence in the Bam H1 W region of the Epstein-Barr virus (EBV) to determine the prevalence of the virus in the cervix. EBV was detected in 131 (40%) of the 327 women. Of the 235 women with normal cytology, 98 (42%) we...

journal_title：Journal of clinical pathology

authors： Taylor Y,Melvin WT,Sewell HF,Flannelly G,Walker F

更新日期：1994-01-01 00:00:00

abstract：:Idoxuridine-treated McCoy cells grown as monolayers in 96 well microplates provide a convenient method for the isolation of Chlamydia trachomatis. Staining of infected monolayers with periodic acid-Schiff reagent (PAS) allows easy recognition of C trachomatis inclusions without the need for dark-ground microscopy. By ...

journal_title：Journal of clinical pathology

authors： Mallinson H,Sikotra S,Arya OP

更新日期：1981-07-01 00:00:00

abstract：AIM:To evaluate the sources of fetal haemoglobin (HbF) as an indicator in cancer. An immunohistochemical study was carried out on some of the most common kinds of cancer. All of these cancers had serologically high levels of HbF as evaluated previously. METHODS:Immunoaffinity-purified anti-HbF was immunohistochemicall...

journal_title：Journal of clinical pathology

authors： Wolk M,Martin JE,Reinus C

更新日期：2006-06-01 00:00:00

abstract：:Guidance by bacteriologists and changes in theatre and ward disciplines have greatly improved the results of urological surgery in recent years. The most noteworthy successes have been in treatment of chronic retention with renal failure, and in prevention of the bacteraemia which may occur following removal of the po...

journal_title：Journal of clinical pathology

authors： MITCHELL JP,GILLESPIE WA

更新日期：1964-09-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) based on the antibody class capture method for the detection of specific IgM against Toxoplasma gondii, using the microtitre plate format, was developed. Antigen binding was detected using a monoclonal antibody, CIE3, conjugated to horseradish peroxidase. Prior mixing of th...

journal_title：Journal of clinical pathology

authors： Payne RA,Joynson DH,Balfour AH,Harford JP,Fleck DG,Mythen M,Saunders RJ

更新日期：1987-03-01 00:00:00

abstract：:As part of a wider survey of infections and defence mechanisms, concentrations of serum immunoglobulins IgG, IgA, and IgM were measured regularly by single radial immunodiffusion in a group of children receiving treatment for acute lymphoblastic leukaemia while in their first remission. IgM concentrations were often m...

journal_title：Journal of clinical pathology

authors： Reid MM,Craft AW,Cox JR

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Serum prostate specific antigen (PSA) increases after radical prostatectomy are thought to indicate recurrent disease, although some suggest they result from benign prostatic epithelial tissue left at surgical margins. AIMS:To investigate whether presence, location, and extent of benign prostatic tissue at ...

journal_title：Journal of clinical pathology

authors： Kernek KM,Koch MO,Daggy JK,Juliar BE,Cheng L

更新日期：2005-07-01 00:00:00

abstract：:One hundred and seventyone antenatal patients were examined for the presence of ;large colony' mycoplasmas in the vagina, and for complement-fixing antibody to Mycoplasma hominis. In 25 patients the findings before and after delivery were compared. In patients from whom M. hominis was grown, antibody was twice as comm...

journal_title：Journal of clinical pathology

authors： Jones DM

更新日期：1967-07-01 00:00:00

abstract：AIMS:To investigate the optimal method for the detection of campylobacters from stool samples by comparing selective culture with membrane filtration and the polymerase chain reaction (PCR). METHODS:Three hundred and forty three stool samples were investigated by each of the three methods mentioned above. Selective cu...

journal_title：Journal of clinical pathology

authors： Kulkarni SP,Lever S,Logan JM,Lawson AJ,Stanley J,Shafi MS

更新日期：2002-10-01 00:00:00

abstract：AIMS:To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. METHODS:Formalin fixed, paraffin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS ...

journal_title：Journal of clinical pathology

authors： Chan CW,Nicholls JM,Sham JS,Dickens P,Choy D

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Serine peptidase inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, has well established associations with inflammation, cancer cell proliferation and carcinogenesis. However, the role of SPINK1 has not been investigated in stage IV colorectal cancer (CRC) patients receiving cetuximab based targete...

journal_title：Journal of clinical pathology

authors： Chen YT,Tsao SC,Tsai HP,Wang JY,Chai CY

更新日期：2016-04-22 00:00:00

abstract：:The arrangement of the T cell receptor and immunoglobulin genes was analysed in lymphoid tissue biopsy specimens from 25 cases of angioimmunoblastic lymphadenopathy. Nineteen cases showed a rearrangement of the gene coding for the beta chain of the T cell receptor, and in one case a clonal rearrangement of immunoglobu...

journal_title：Journal of clinical pathology

authors： O'Connor NT,Crick JA,Wainscoat JS,Gatter KC,Stein H,Falini B,Mason DY

更新日期：1986-11-01 00:00:00

abstract：:During a two-year period of observation Bacteroides species were isolated from specimens of pus and vaginal swabs from 115 patients in this hospital. Thirty-five representative strains proved on examination to be Bacteroides fragilis. Minimal inhibitory and minimal bactericidal concentrations of six antibiotics for th...

journal_title：Journal of clinical pathology

authors： Ingham HR,Selkon JB,Codd AA,Hale JH

更新日期：1968-07-01 00:00:00

abstract：AIMS:Endotoxin detection assays are not validated for use in end-stage kidney disease (ESKD). We investigated the accuracy and precision of the kinetic turbidimetric Limulus amoebocyte lysate (LAL) assay to detect endotoxin in plasma from patients with ESKD. Optimisation of endotoxin recovery from plasma using the dete...

journal_title：Journal of clinical pathology

authors： Wong J,Jeraj H,Vilar E,Viljoen A,Farrington K

更新日期：2015-01-01 00:00:00

abstract：:Colonising Campylobacter pyloridis were identified histologically in gastric biopsy specimens from 89% of 83 patients with non-ulcer dyspepsia and chronic gastritis, but not in 58 dyspeptic patients with normal mucosa. The presence and population density of organisms was associated with the presence of intraepithelial...

journal_title：Journal of clinical pathology

authors： Wyatt JI,Rathbone BJ,Heatley RV

更新日期：1986-08-01 00:00:00

abstract：:Lymphoid tissue of the endometrium was analysed by histological, immunohistological, and electron microscopical methods in 10 healthy uteri. A panel of monoclonal antibodies recognising macrophages (OKMI), HLA-DR antigen, B lymphocytes, T lymphocytes and their subsets, and dendritic reticulum cells was used in a two s...

journal_title：Journal of clinical pathology

authors： Morris H,Edwards J,Tiltman A,Emms M

更新日期：1985-06-01 00:00:00

abstract：:Methods are described for the estimation of plasma and urine alpha-amino nitrogen by the colorimetric ninhydrin reaction; in the method for urine, both ammonia and urea are separated by a rapid ion-exchange resin procedure. Two methods of estimation are given; one has the advantage of great simplicity, but involves th...

journal_title：Journal of clinical pathology

authors： MATTHEWS DM,MUIR GG,BARON DN

更新日期：1964-03-01 00:00:00

abstract：:Review of published work and analysis of clinical data and pathology of four biopsy specimens from two patients with laryngeal contact granuloma showed that its peptic origin was derived from a gastro-oesophago-laryngeal reflux. It is proposed that the term "peptic granuloma" should be given to this phenomenon. This t...

journal_title：Journal of clinical pathology

authors： Miko TL

更新日期：1989-08-01 00:00:00

abstract：AIMS:To assess the distribution of gamma delta T-cells in the human bronchial tree; and to compare quantitatively the differences between gamma delta T-cell numbers in different parts of the airway wall in smokers and non-smokers. METHODS:Full thickness bronchial wall sections were taken from 10 whole lung specimens f...

journal_title：Journal of clinical pathology

authors： Richmond I,Pritchard GE,Ashcroft T,Corris PA,Walters EH

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:The terminology applied to vascular anomalies has been variable in previously published literature making interpretation suboptimal. The International Society for the Study of Vascular Anomalies (ISSVA) has proposed a revised classification based on clinical features and histopathological findings. This clas...

journal_title：Journal of clinical pathology

authors： Al-Adnani M,Williams S,Rampling D,Ashworth M,Malone M,Sebire NJ

更新日期：2006-12-01 00:00:00

abstract：AIMS:The assessment of lymphatic vessel density (LVD) has been suggested as a tool to determine the metastatic risk of neoplasias. On this premise, the authors aimed to verify whether progression risk of stage I colorectal cancer may be related to LVD. The authors also evaluated and correlated vascular endothelial grow...

journal_title：Journal of clinical pathology

authors： Barresi V,Reggiani-Bonetti L,Di Gregorio C,De Leon MP,Barresi G

更新日期：2011-01-01 00:00:00

abstract：AIMS:To investigate how the biopsy Gleason score (GS) and the clinical risk classification have been changed by the reporting rules. METHODS:565 prostate biopsy specimens were reassessed. Each Gleason pattern, 1 to 5, was interpreted according to the modified Gleason grading system proposed by the International Societ...

journal_title：Journal of clinical pathology

authors： Kuroiwa K,Uchino H,Yokomizo A,Naito S

更新日期：2009-03-01 00:00:00