Aortic cholesteryl esterase. Influence of bile salts.

Abstract:

:The in vitro activity of cholesteryl ester hydrolase preparations of rat and rabbit aortas was assayed in the presence of the taurine and glycine conjugates of cholic, chenodeoxycholic, deoxycholic and lithocholic acids or in the presence of Triton X-100 and Tween-20. Maximum activity was obtained with tauro- or glycocholic acids. As in the case of pancreatic cholesteryl esterase, trihydroxycholanoic acid derivatives may serve an obligatory function.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Kothari HV,Kritchevsky D

doi

10.1016/0021-9150(78)90072-2

subject

Has Abstract

pub_date

1978-11-01 00:00:00

pages

371-5

issue

3

eissn

0021-9150

issn

1879-1484

pii

0021-9150(78)90072-2

journal_volume

31

pub_type

杂志文章
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    abstract:BACKGROUND:Atherosclerotic plaques are heterogeneous with respect to inflammation, calcification, vascularity, oxygen, and temperature. We hypothesized that they also vary in pH and measured pH in living human carotid endarterectomized atherosclerotic plaques (CEA), Watanabe heritable hyperlipidemic (WHHL) rabbit aorta...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(02)00018-7

    authors: Naghavi M,John R,Naguib S,Siadaty MS,Grasu R,Kurian KC,van Winkle WB,Soller B,Litovsky S,Madjid M,Willerson JT,Casscells W

    更新日期:2002-09-01 00:00:00

  • Relationships of night/day heart rate ratio with carotid intima media thickness and markers of arterial stiffness.

    abstract:OBJECTIVES:To analyze the relationship between office and ambulatory heart rate, and its variability, and arterial stiffness in patients with primary arterial hypertension. METHODS:A cross-sectional study was conducted in a primary care setting, with the inclusion of 356 hypertensive patients aged 30-80 years. Office ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2011.03.037

    authors: García-Ortiz L,García-García A,Ramos-Delgado E,Patino-Alonso MC,Recio-Rodríguez JI,Rodríguez-Sánchez E,Gómez-Marcos MA

    更新日期:2011-08-01 00:00:00

  • Skeletal muscle fiber distribution influences serum high-density lipoprotein cholesterol level.

    abstract::Earlier we have shown a significant positive association between muscle fiber distribution, i.e. percentage of slow-twitch (ST) fibers in the vastus lateralis muscle, and serum high-density lipoprotein cholesterol (HDL-C) level. This association may be due to the fact that ST fibers have a high capacity for oxidative ...

    journal_title:Atherosclerosis

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    doi:10.1016/0021-9150(95)05652-1

    authors: Tikkanen HO,Näveri H,Härkönen M

    更新日期:1996-02-01 00:00:00

  • Modified plasma-derived lipoproteins in human atherosclerotic plaques.

    abstract::Low density lipoproteins extracted from surgical specimens of human atherosclerotic plaques (A-LDL) showed altered electrophoretic mobility indicating a greater negative charge than that of plasma LDL (P-LDL). A-LDL but not P-LDL showed high affinity binding/degradation by human monocyte-derived macrophages; this was ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(88)90011-1

    authors: Shaikh M,Martini S,Quiney JR,Baskerville P,La Ville AE,Browse NL,Duffield R,Turner PR,Lewis B

    更新日期:1988-02-01 00:00:00

  • Low density lipoprotein metabolism by cultured skin fibroblasts from atherosclerotic patients.

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    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(82)90148-4

    authors: Behrman RG,Wynn V

    更新日期:1982-04-01 00:00:00

  • Aortic glutathione metabolic status: time-dependent alterations in fat-fed rabbits.

    abstract::Little is known about the vascular metabolic status of glutathione (GSH), which is crucial in cell antioxidant protection, in experimental conditions like high-fat diet-induced atherosclerosis. This issue was, therefore, investigated in two groups of seven rabbits fed a 0.5% cholesterol-, 5% lard- and 5% peanut oil-en...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2003.11.014

    authors: Lapenna D,Pierdomenico SD,Ciofani G,Giamberardino MA,Cuccurullo F

    更新日期:2004-03-01 00:00:00

  • A major gene influences variation in large HDL particles and their response to diet in baboons.

    abstract::Some baboons accumulate appreciable amounts of large apoE-rich HDLs (HDL(1)) which are similar to those reported in humans with several different dyslipoproteinemias. We estimated HDL(1) cholesterol concentrations by gradient gel electrophoresis of serum samples obtained from 634 pedigreed baboons fed with three diets...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(02)00015-1

    authors: Rainwater DL,Kammerer CM,Cox LA,Rogers J,Carey KD,Dyke B,Mahaney MC,McGill HC Jr,VandeBerg JL

    更新日期:2002-08-01 00:00:00

  • Heart valve calcification in young patients with systemic lupus erythematosus: a window to premature atherosclerotic vascular morbidity and a risk factor for all-cause mortality.

    abstract::The objective of the study was to evaluate the association between heart valve calcification and atherosclerosis and outcome in systemic lupus erythematosus (SLE). One-hundred and seven patients with SLE (mean age 45.9 +/- 14.7 years) were studied by 2D transthoracic echocardiography. Mitral annulus calcification (MAC...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2005.06.021

    authors: Molad Y,Levin-Iaina N,Vaturi M,Sulkes J,Sagie A

    更新日期:2006-04-01 00:00:00

  • A novel oxidized low-density lipoprotein marker, serum amyloid A-LDL, is associated with obesity and the metabolic syndrome.

    abstract:BACKGROUND:The putative association between the novel oxidized low-density lipoprotein markers, serum amyloid A-LDL (SAA-LDL) and alpha1-antitrypsin-LDL (AT-LDL), and obesity and the metabolic syndrome (MetS) has not been previously studied. In the present report, we investigated the levels of SAA-LDL and AT-LDL in rel...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2008.09.017

    authors: Kotani K,Satoh N,Kato Y,Araki R,Koyama K,Okajima T,Tanabe M,Oishi M,Yamakage H,Yamada K,Hattori M,Shimatsu A,Japan Obesity and Metabolic Syndrome Study Group.

    更新日期:2009-06-01 00:00:00

  • Lysosomal acid lipase deficiency--an under-recognized cause of dyslipidaemia and liver dysfunction.

    abstract::Lysosomal acid lipase deficiency (LAL-D) is a rare autosomal recessive lysosomal storage disease caused by deleterious mutations in the LIPA gene. The age at onset and rate of progression vary greatly and this may relate to the nature of the underlying mutations. Patients presenting in infancy have the most rapidly pr...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2014.04.003

    authors: Reiner Ž,Guardamagna O,Nair D,Soran H,Hovingh K,Bertolini S,Jones S,Ćorić M,Calandra S,Hamilton J,Eagleton T,Ros E

    更新日期:2014-07-01 00:00:00

  • Use of proton pump inhibitors and risk of ischemic events in the general population.

    abstract:BACKGROUND AND AIMS:A potential increased risk of cardiovascular events has been suggested for proton pump inhibitors (PPIs), the most commonly prescribed drugs for the management of upper gastrointestinal disorders. We aimed to estimate the risk of hospitalization for cardio/cerebrovascular (CV) events in a cohort of ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2018.08.035

    authors: Casula M,Scotti L,Galimberti F,Mozzanica F,Tragni E,Corrao G,Catapano AL

    更新日期:2018-10-01 00:00:00

  • Transcriptional regulation of the human sterol 27-hydroxylase gene (CYP27) and promoter mapping.

    abstract::Recent evidence suggests that sterol 27-hydroxylase may play a role in cholesterol homeostasis and affect atherogenesis. The major objective of the study was to map and characterize the sterol 27-hydroxylase (CYP27) promoter region. Here we show that CYP27 gene has a TATA-less promoter and transcription initiates at a...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(00)00654-7

    authors: Segev H,Honigman A,Rosen H,Leitersdorf E

    更新日期:2001-06-01 00:00:00

  • Biosynthesis of aortic collagen and glycosaminoglycan following immunological injury.

    abstract::The effect of immunological injury upon the early in vivo changes in aortic connective tissue metabolism was studied. It was found that a single antigen (bovine serum albumin), when administered in multiple doses, activated collagen synthesis and increased the rate of lgycosaminoglycan synthesis in the arterial wall. ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(79)90003-0

    authors: Rokosova B,Bentley JP

    更新日期:1979-04-01 00:00:00

  • Background differences in baseline and stimulated MMP levels influence abdominal aortic aneurysm susceptibility.

    abstract:OBJECTIVE:Evidence has demonstrated profound influence of genetic background on cardiovascular phenotypes. Murine models in Marfan syndrome (MFS) have shown that genetic background-related variations affect thoracic aortic aneurysm formation, rupture, and lifespan of mice. MFS mice with C57Bl/6 genetic background are l...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2015.10.006

    authors: Dale MA,Suh MK,Zhao S,Meisinger T,Gu L,Swier VJ,Agrawal DK,Greiner TC,Carson JS,Baxter BT,Xiong W

    更新日期:2015-12-01 00:00:00

  • Effects of probucol on low density lipoprotein removal and high density lipoprotein synthesis.

    abstract::The possible mechanisms of action of probucol on the metabolism of low density lipoprotein and of high density lipoprotein were studied in 5 hyperlipidaemic subjects. The kinetics of LDL-B protein and of HDL-AI protein were determined by 2-pool analysis of specific radioactivity-time curves after reinjection of 131I-l...

    journal_title:Atherosclerosis

    pub_type: 临床试验,杂志文章

    doi:10.1016/0021-9150(81)90117-9

    authors: Nestel PJ,Billington T

    更新日期:1981-01-01 00:00:00

  • Effects of nitric oxide and superoxide on relaxation in human artery and vein.

    abstract::Endothelium-derived relaxing and contracting factors play an important role in atherosclerosis, re-stenosis and graft survival. Internal thoracic artery (ITA) and saphenous vein (SV) are used as conduit vessels in coronary artery bypass graft surgery (CABG). The long-term graft patency rate is higher with ITA than SV....

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(97)00114-7

    authors: Hamilton CA,Berg G,Mcintyre M,Mcphaden AR,Reid JL,Dominiczak AF

    更新日期:1997-08-01 00:00:00

  • Associations between IgG antibody to oral organisms and carotid intima-medial thickness in community-dwelling adults.

    abstract:AIMS:The aims of this study are to describe the relationships between IgG antibodies to 17 oral organisms and atherosclerosis as indexed by carotid intima-medial wall thickness (IMT) and to evaluate the role of smoking. METHODS AND RESULTS:Our study is based on a subset of participants in the Atherosclerosis Risk in C...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2005.03.017

    authors: Beck JD,Eke P,Lin D,Madianos P,Couper D,Moss K,Elter J,Heiss G,Offenbacher S

    更新日期:2005-12-01 00:00:00

  • High serum concentrations of soluble E-selectin in patients with impaired glucose tolerance with hyperinsulinemia.

    abstract::High serum concentrations of soluble adhesion molecules are present in diabetics, but whether similar levels are present in patients with impaired glucose tolerance (IGT) is unclear. We measured serum concentrations of soluble intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), an...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(99)00487-6

    authors: Matsumoto K,Miyake S,Yano M,Ueki Y,Tominaga Y

    更新日期:2000-10-01 00:00:00

  • Serum selenium concentration and risk of ischaemic heart disease in a prospective cohort study of 3000 males.

    abstract::Whether an association, causative or not, exists between the level of serum selenium and the risk of ischaemic heart disease (IHD) remains unsettled. We investigated the issue in a cohort of 3387 males aged 53-74 years (mean 63). Based on information about health status, life-style and socioeconomic factors given in a...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(92)90035-f

    authors: Suadicani P,Hein HO,Gyntelberg F

    更新日期:1992-09-01 00:00:00

  • Cholesterol efflux capacity is impaired in subjects with an elevated Fatty Liver Index, a proxy of non-alcoholic fatty liver disease.

    abstract:BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) parallels the obesity epidemic and associates with components of the metabolic syndrome (MetS). Cholesterol efflux capacity (CEC) represents a key metric of high density lipoprotein (HDL) function which may predict atherosclerotic cardiovascular disease (CVD...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2018.07.028

    authors: van den Berg EH,Gruppen EG,Ebtehaj S,Bakker SJL,Tietge UJF,Dullaart RPF

    更新日期:2018-10-01 00:00:00

  • Blood pressure disturbances and endothelial dysfunction markers in children and adolescents with type 1 diabetes.

    abstract:OBJECTIVE:Being the earliest step on the way to atherosclerosis, endothelial dysfunction is particularly escalated in diabetes. This study aimed at assessing endothelial dysfunction and blood pressure disturbances in young patients with type 1 diabetes mellitus (T1DM) and defining their interrelations. METHODS:The stu...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2014.09.006

    authors: Machnica L,Deja G,Polanska J,Czupryniak L,Szymanska-Garbacz E,Loba J,Jarosz-Chobot P

    更新日期:2014-11-01 00:00:00

  • Association between nutrient intake and peripheral artery disease: results from the InCHIANTI study.

    abstract:BACKGROUND:Little is known about the relationship between dietary patterns and peripheral arterial disease (PAD). Our aim was to estimate the association between nutrient intake and diagnosis of PAD. METHODS AND RESULTS:We assessed the nutrient intake of 1251 home-dwelling subjects enrolled in the InCHIANTI study, mea...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.atherosclerosis.2005.07.016

    authors: Antonelli-Incalzi R,Pedone C,McDermott MM,Bandinelli S,Miniati B,Lova RM,Lauretani F,Ferrucci L

    更新日期:2006-05-01 00:00:00

  • Age-associated ultrastructural changes in the aortic intima of rats with diet-induced hypercholesterolemia.

    abstract::The ultrastructure of the aortic intima and serum lipid levels in Fischer 344 rats were examined at the ages of 12, 18 and 24 months after feeding the animals an atherogenic diet (2% cholesterol, 0.25% sodium cholate, 5% beef fat) for 6 months. Structural changes in the intima were noticeable only at the age of 24 mon...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(89)90114-7

    authors: Nakamura H,Izumiyama N,Nakamura K,Ohtsubo K

    更新日期:1989-10-01 00:00:00

  • Effect of treatment with human apolipoprotein A-I on atherosclerosis in uremic apolipoprotein-E deficient mice.

    abstract:OBJECTIVE:Uremia markedly increases the risk of atherosclerosis. Thus, effective anti-atherogenic treatments are needed for uremic patients. This study examined effects of non-lipidated recombinant human apoA-I (h-apoA-I) and a recombinant trimeric apoA-I molecule (TripA-I) on lipid metabolism and atherosclerosis in ur...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2008.04.041

    authors: Pedersen TX,Bro S,Andersen MH,Etzerodt M,Jauhiainen M,Moestrup S,Nielsen LB

    更新日期:2009-02-01 00:00:00

  • Effect of chronic renal failure and methylprednisolone treatment on the uptake of labelled plasma cholesterol into the aorta of normocholesterolemic rabbits.

    abstract::The effects of chronic renal failure (CRF) and corticosteroid treatment on the aortic uptake of labelled free and esterified cholesterol (FC and EC) were investigated in normocholesterolemic rabbits. Methylprednisolone, 0.4 mg/day, or placebo was administered for 14 weeks to rabbits with normal renal function and with...

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    pub_type: 杂志文章

    doi:10.1016/0021-9150(83)90155-7

    authors: Tvedegaard E,Szpirt W,Nielsen M

    更新日期:1983-05-01 00:00:00

  • Potential pathological roles for oxidized low-density lipoprotein and scavenger receptors SR-AI, CD36, and LOX-1 in aortic valve stenosis.

    abstract:OBJECTIVE:To clarify the potential mechanisms by which oxidized low-density lipoprotein (oxLDL) could contribute to the progression of aortic valve stenosis (AVS). METHODS:We investigated a total of 46 stenotic and 20 control human aortic valves. The mRNA expression levels of scavenger receptor class A type 1 (SR-A1),...

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    doi:10.1016/j.atherosclerosis.2014.05.933

    authors: Syväranta S,Alanne-Kinnunen M,Oörni K,Oksjoki R,Kupari M,Kovanen PT,Helske-Suihko S

    更新日期:2014-08-01 00:00:00

  • A novel antioxidant 3,7-dihydroxy-isoflav-3-ene (DHIF) inhibits neointimal hyperplasia after vessel injury attenuating reactive oxygen species and nuclear factor-kappaB signaling.

    abstract::Reactive oxygen species (ROS) contribute to neointimal smooth muscle proliferation by yet to be defined mechanisms. We examined the effects of a novel isoflavone 3,7-dihydroxy-isoflav-3-ene (DHIF) on development of neointimal lesions in relation to ROS elevations and cell signaling in injured arteries. Carotid arterie...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2008.09.005

    authors: Kanellakis P,Pomilio G,Walker C,Husband A,Huang JL,Nestel P,Agrotis A,Bobik A

    更新日期:2009-05-01 00:00:00

  • The influence of hypoalbuminemia in the generation of nephrotic hyperlipidemia.

    abstract::Lipoprotein measurements in a group of 29 patients with massive proteinuria and without hypoalbuminemia, were compared with those observed in matched controls and patients with overt nephrotic syndrome to assess the influence of plasma albumin concentration and proteinuria in modulating blood lipid levels. Plasma apop...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(96)05905-9

    authors: Joven J,Espinel E,Simó JM,Vilella E,Camps J,Oliver A

    更新日期:1996-10-25 00:00:00

  • Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors.

    abstract:OBJECTIVE:Blood glucose fluctuations have been found to be relevant to the progression of atherosclerosis in patients with type 2 diabetes and to be more detrimental for the development of atherosclerosis than the sustained hyperglycemia. We aim at evaluating the effect of blunted daily acute glucose fluctuations by DP...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.atherosclerosis.2012.12.018

    authors: Barbieri M,Rizzo MR,Marfella R,Boccardi V,Esposito A,Pansini A,Paolisso G

    更新日期:2013-04-01 00:00:00

  • Can the extent of epicardial adipose tissue thickness or the presence of descending thoracic aortic calcification predict significant coronary artery stenosis in patients with a zero coronary calcium score on multi-detector CT?

    abstract:OBJECTIVE:The purpose of this study was to evaluate whether the extent of epicardial adipose tissue (EAT) thickness or the presence of descending thoracic aortic calcification on multi-detector CT (MDCT) can predict the presence of significant coronary artery stenosis in patients with negative coronary artery calcium (...

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    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2010.01.047

    authors: Lee HY,Song IS,Yoo SM,Rho JY,Moon JY,White CS

    更新日期:2010-10-01 00:00:00