Abstract：
:Earlier we have shown a significant positive association between muscle fiber distribution, i.e. percentage of slow-twitch (ST) fibers in the vastus lateralis muscle, and serum high-density lipoprotein cholesterol (HDL-C) level. This association may be due to the fact that ST fibers have a high capacity for oxidative energy metabolism and a high number of surrounding capillaries. These fibers have a high capacity to metabolize fatty acids liberated by lipoprotein lipase (LPL) from triglyceride-rich lipoproteins. This in turn elevates serum HDL-C levels. Thus, a high percentage of ST fibers (ST-%) may be one factor having a beneficial effect on serum HDL-C concentration. A high ST-% may also increase the likelihood that a person will become involved in an endurance type of physical activity, which further increases serum HDL-C concentration by increasing further LPL activity in the capillary bed of skeletal muscle. In this paper we present a hypothetical background of the role that ST fibers may have on serum lipid and lipoprotein profile.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Tikkanen HO,Näveri H,Härkönen Mdoi
10.1016/0021-9150(95)05652-1subject
Has Abstractpub_date
1996-02-01 00:00:00pages
1-5issue
1-2eissn
0021-9150issn
1879-1484pii
0021-9150(95)05652-1journal_volume
120pub_type
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