Precursor of mast cells fixed in the skin of mice.

Abstract:

:The presence and origin of mast-cell precursors fixed in the skin tissue of mice were investigated. Giant granules of beige (C57BL/6-bh'/bg', Chediak-Higashi syndrome) mice were used to distinguish different populations of mast cells. Pieces of the skin were grafted from the intact WBB6F1 (WB X C57BL/6)F1-+/+ mice into the back of the WBB6F1-+/+ mice which had been irradiated and injected with bone marrow cells of C57BL/6-bg'/bg'leads to +/+ chimeras). Although the number of mast cells in the skin grafts decreased after the transplantation, the mast-cell precursors circulating in the bloodstream of bg'/bg' leads to +/+ chimeras (bg'/bg' type) did not seem to enter into the skin grafts, because most of mast cells were of +/+ type after the recovery of mast-cell number to pregrafting levels. As a considerable proportion of +/+-type mast cells was labeled with 3H-thymidine, the recovery of mast-cell number in the grafts was attributed to the proliferation and differentiation of +/+-type precursor cells fixed in the skin tissue of the donor. On the other hand, the skin of WBB6F1-W/Wv mice seemed to be depleted of fixed precursors, because most of mast cells were of bg'/bg'-type in skin grafted from WBB6F1-W/Wv mice to bgJ/bgJ leads to +/+ chimeras. Since the fixed precursor cells which proliferate and differentiate into mast cells after skin grafting may be transferred to WBB6F1-W/Wv mice by bone marrow transplantation, such precursor cells seem to have been derived from the bone marrow.

journal_name

J Cell Physiol

authors

Matsuda H,Kitamura Y,Sonoda T,Imori T

doi

10.1002/jcp.1041080315

subject

Has Abstract

pub_date

1981-09-01 00:00:00

pages

409-15

issue

3

eissn

0021-9541

issn

1097-4652

journal_volume

108

pub_type

杂志文章
  • Isolation, Characterization, and Establishment of Spontaneously Immortalized Cell Line HRPE-2S With Stem Cell Properties.

    abstract::The retinal pigment epithelium is a monolayer of highly specialized pigmented cells located between the neural retina and the Bruch's membrane of the choroid. RPE cells play a crucial role in the maintenance and function of the underlying photoreceptors. This study introduces a spontaneously arising human retinal pigm...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.25729

    authors: Shams Najafabadi H,Soheili ZS,Samiei S,Ahmadieh H,Ranaei Pirmardan E,Masoumi M

    更新日期:2017-10-01 00:00:00

  • Zinc finger E-box binding homeobox 1 and atherosclerosis: New insights and therapeutic potential.

    abstract::Zinc finger E-box binding homeobox 1 (ZEB1), an important transcription factor belonging to the ZEB family, plays a crucial role in regulating gene expression required for both normal physiological and pathological processes. Accumulating evidence has shown that ZEB1 participates in the initiation and progression of a...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章,评审

    doi:10.1002/jcp.30177

    authors: Li H,Zou J,Yu XH,Ou X,Tang CK

    更新日期:2020-12-04 00:00:00

  • Reduction of DNA primase activity in aging but still proliferating cells.

    abstract::The basis of the well-known decline in cell proliferation with increasing passage number of human diploid fibroblast-like cell cultures is not known. It has been found that DNA synthesis was deficient in the remaining but still proliferating cells, but when appropriate corrections reflecting the remaining dividing cel...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041430107

    authors: Collins JM,Chu AK

    更新日期:1990-04-01 00:00:00

  • Calcium sources used by post-natal human myoblasts during initial differentiation.

    abstract::Increases in cytoplasmic Ca(2+) are crucial for inducing the initial steps of myoblast differentiation that ultimately lead to fusion; yet the mechanisms that produce this elevated Ca(2+) have not been fully resolved. For example, it is still unclear whether the increase comes exclusively from membrane Ca(2+) influx o...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.20679

    authors: Arnaudeau S,Holzer N,König S,Bader CR,Bernheim L

    更新日期:2006-08-01 00:00:00

  • Modulatory effects of statins on the autophagy: A therapeutic perspective.

    abstract::Autophagy is considered as an important mechanism for maintaining homeostasis and responsible for the degradation of superfluous or potentially toxic components and organelles. Autophagy impairment is associated with a number of pathological conditions, such as aging, neurological disorders, cancer, and infection. Aut...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章,评审

    doi:10.1002/jcp.29227

    authors: Ashrafizadeh M,Ahmadi Z,Farkhondeh T,Samarghandian S

    更新日期:2020-04-01 00:00:00

  • Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo.

    abstract::Endothelial cells are known to bind to laminin, and two peptides derived from the laminin A (CTFALRGDNP) and B1 (CDPGYIGSR) chains block the capillary-like tube formation on a laminin-rich basement membrane matrix, Matrigel. In the present study, we have used various in vitro and in vivo assays to investigate the angi...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041530324

    authors: Grant DS,Kinsella JL,Fridman R,Auerbach R,Piasecki BA,Yamada Y,Zain M,Kleinman HK

    更新日期:1992-12-01 00:00:00

  • Influence of cyclosporine A on growth and extracellular matrix synthesis of human fibroblasts.

    abstract::Cyclosporine A (CyA) is a powerful nonsteroidal immunosuppressive agent used to prevent graft rejection of organ and bone marrow transplants. A major side effect observed can be attributed to the fibroblast and its functions: proliferation of fibroblasts and formation of fibrotic tissue in the gingiva (fibrous hyperpl...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041520222

    authors: Willershausen-Zönnchen B,Lemmen C,Schumacher U

    更新日期:1992-08-01 00:00:00

  • Role of p53 family members in apoptosis.

    abstract::p53-mediated apoptosis involves multiple mechanisms. A number of p53-regulated apoptosis-related genes have been identified. Some of these genes encode proteins that are important in controlling the integrity of mitochondria while the others code for membrane death receptors. p53 may also induce apoptosis by interferi...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章,评审

    doi:10.1002/(SICI)1097-4652(200002)182:2<171::AID-JCP5

    authors: Sheikh MS,Fornace AJ Jr

    更新日期:2000-02-01 00:00:00

  • Modulation of drug resistance in homoharringtonine-resistant C-1300 neuroblastoma cells with cyclosporine A and dipyridamole.

    abstract::The development of resistance accounts for therapy failure in the majority of advanced cases of neuroblastoma in children. A new transplantable murine C-1300 neuroblastoma cell line was developed in vitro, by repeated exposure of a sensitive cell line to increasing, but sublethal, doses of Homoharringtonine (HHT). The...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041480319

    authors: Tebbi CK,Chervinsky D,Baker RM

    更新日期:1991-09-01 00:00:00

  • GTP-binding inhibitors increase LRRK2-linked ubiquitination and Lewy body-like inclusions.

    abstract::Parkinson's disease (PD) is one of the most common movement disorders with loss of dopaminergic neurons and the presence of Lewy bodies in certain brain areas. However, it is not clear how Lewy body (inclusion with protein aggregation) formation occurs. Mutations in leucine-rich repeat kinase 2 (LRRK2) can cause a gen...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.29632

    authors: Thomas JM,Wang X,Guo G,Li T,Dai B,Nucifora LG,Nucifora FC Jr,Liu Z,Xue F,Liu C,Ross CA,Smith WW

    更新日期:2020-10-01 00:00:00

  • The effect of metabolic inhibition on ion contents and sodium exchange in human lymphocytes.

    abstract::Lymphocytes depleted of ATP by incubation in iodoacetate (IAA) and nitrogen (N2) lost K and gained Na. Isotopic Na exchange showed a fast fraction and a slower exponential fraction, the latter conventionally assumed to reflect surface membrane properties. The gain of cell Na was not accounted for by a decrease in 22Na...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041100312

    authors: Negendank W,Shaller C

    更新日期:1982-03-01 00:00:00

  • MiR-199a-3p inhibition facilitates cardiomyocyte differentiation of embryonic stem cell through promotion of MEF2C.

    abstract::MicroRNAs (miRNAs) is a small molecule (19-25 nucleotide) noncoding RNA that inhibits the expression of target messenger RNA (mRNA) at the posttranscriptional level as an endogenous regulator. There is an increasing evidence that miR-199a-3p has a significant effect on the development of multiple tumors. However, the ...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.28899

    authors: Chen HP,Wen J,Tan SR,Kang LM,Zhu GC

    更新日期:2019-12-01 00:00:00

  • Retromer promotes immune quiescence by suppressing Spätzle-Toll pathway in Drosophila.

    abstract::The Toll and Toll-like receptor signaling pathways are evolutionarily conserved pathways that regulate innate immunity in insects and mammals. While efforts have been made to clarify the signal transduction events that occur during infection, much less is known about the components that maintain immune quiescence. Her...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.24472

    authors: Zhou B,Yun EY,Ray L,You J,Ip YT,Lin X

    更新日期:2014-04-01 00:00:00

  • Ascorbic Acid Induces Necrosis in Human Laryngeal Squamous Cell Carcinoma via ROS, PKC, and Calcium Signaling.

    abstract::Ascorbic acid induces apoptosis, autophagy, and necrotic cell death in cancer cells. We investigated the mechanisms by which ascorbic acid induces death in laryngeal squamous cell carcinoma Hep2 cells. Ascorbic acid markedly reduced cell viability and induced death without caspase activation and an increase in cytochr...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.25438

    authors: Baek MW,Cho HS,Kim SH,Kim WJ,Jung JY

    更新日期:2017-02-01 00:00:00

  • Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF.

    abstract::We investigated gene expression profiles of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in differentiated and non-differentiated retinal pigment epithelial (RPE) cells during oxidative stress. Human RPE cells were grown in culture on laminin-coated flasks to obtain differenti...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.10026

    authors: Ohno-Matsui K,Morita I,Tombran-Tink J,Mrazek D,Onodera M,Uetama T,Hayano M,Murota SI,Mochizuki M

    更新日期:2001-12-01 00:00:00

  • Nitric oxide and endothelin secretion by brain microvessel endothelial cells: regulation by cyclic nucleotides.

    abstract::Endothelin (ET)-1 was originally characterized as a potent vasoconstrictor peptide secreted by vascular endothelial cells. It possesses a wide range of biological activities within the cardiovascular system and in other organs, including the brain. Also secreted by endothelial cells, nitric oxide (NO), has recently be...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041550114

    authors: Durieu-Trautmann O,Fédérici C,Créminon C,Foignant-Chaverot N,Roux F,Claire M,Strosberg AD,Couraud PO

    更新日期:1993-04-01 00:00:00

  • TSPO ligand FGIN-1-27 controls priapism in sickle cell mice via endogenous testosterone production.

    abstract::Priapism, a prolonged penile erection in the absence of sexual arousal, is common among patients with sickle cell disease (SCD). Hypogonadism is also common in patients with SCD. While the administration of exogenous testosterone reverses hypogonadism, it is contraceptive. We hypothesized that the stimulation of endog...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.30075

    authors: Musicki B,Karakus S,La Favor JD,Chen H,Silva FH,Sturny M,Zirkin BR,Burnett AL

    更新日期:2020-09-24 00:00:00

  • Perlecan Heparan Sulfate Is Required for the Inhibition of Smooth Muscle Cell Proliferation by All-trans-Retinoic Acid.

    abstract::Smooth muscle cell (SMC) proliferation is a key process in stabilization of atherosclerotic plaques, and during restenosis after interventions. A clearer understanding of SMC growth regulation is therefore needed to design specific anti-proliferative therapies. Retinoic acid has been shown to inhibit proliferation of ...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.24731

    authors: Tran-Lundmark K,Tannenberg P,Rauch BH,Ekstrand J,Tran PK,Hedin U,Kinsella MG

    更新日期:2015-02-01 00:00:00

  • Variations in the cell-free translating apparatus of cultured animal cells as a function of time during cell growth.

    abstract::Vero M3 cells, a line derived from the kidney of an African Green Monkey, display certain alterations in their protein synthetic apparatus as a function of time during a growth cycle. (Growth cycle here refers to exponential growth of unsynchronized cells in culture and their subsequent passage into the stationary pha...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1040860104

    authors: Engelhardt DL,Sarnoski J

    更新日期:1975-08-01 00:00:00

  • Chemically and virally transformed cells able to grow without anchorage in serum-free medium: evidence for an autocrine growth factor.

    abstract::BA10-IR transformed cells, obtained by treating Syrian hamster embryo fibroblasts (HEF) with 7-methylbenz(a)anthracene and cultivated for a long period, are highly tumorigenic and grow in suspension as aggregates (spheroids) (Levy et al., 1976). They also grow in attached form or as spheroids in serum-free (S-) synthe...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041310206

    authors: Xin LW,Jullien P,Lawrence DA,Pironin M,Vigier P

    更新日期:1987-05-01 00:00:00

  • CircHIPK3 promotes proliferation and invasion in nasopharyngeal carcinoma by abrogating miR-4288-induced ELF3 inhibition.

    abstract::Circular RNAs (circRNAs) are reported to regulate the development and progression of multiple cancers. However, the functions of circRNAs in nasopharyngeal carcinoma (NPC) are unclear. In this study, we identified that circular homeodomain interacting protein kinase 3 (circHIPK3) was highly expressed in NPC tissues an...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.27041

    authors: Ke Z,Xie F,Zheng C,Chen D

    更新日期:2019-02-01 00:00:00

  • Plasminogen activator inhibitor-1 deficiency suppresses osteoblastic differentiation of mesenchymal stem cells in mice.

    abstract::Plasminogen activator inhibitor-1 (PAI-1) is known as an inhibitor of fibrinolytic system. Previous studies suggest that PAI-1 is involved in the pathogenesis of osteoporosis induced by ovariectomy, diabetes, and glucocorticoid excess in mice. However, the roles of PAI-1 in early-stage osteogenic differentiation have ...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.27655

    authors: Takafuji Y,Tatsumi K,Ishida M,Kawao N,Okada K,Matsuo O,Kaji H

    更新日期:2019-06-01 00:00:00

  • Lineage-negative bone marrow cells travel bidirectionally in the olfactory migratory stream but maintain hematopoietic phenotype.

    abstract::The mammalian olfactory system is a physiologically plastic region of the brain with the potential to support implanted stem cells. We performed direct injection of lineage-negative (lin-neg), green fluorescent protein-positive (GFP+) bone marrow cells into the olfactory bulb to assess cell survival and motility withi...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.20123

    authors: Moore BE,Colvin GA,Dooner MS,Quesenberry PJ

    更新日期:2005-01-01 00:00:00

  • FOXO3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy.

    abstract::Embryo implantation is essential for normal pregnancy, and the process of decidualization is critical for embryo implantation. However, the mechanism of decidualization during early pregnancy is still unknown. Forkhead box O3a (FOXO3a) is the most important functional transcription factor of the forkhead box family an...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.27167

    authors: Long J,Yang CS,He JL,Liu XQ,Ding YB,Chen XM,Tong C,Peng C,Wang YX,Gao RF

    更新日期:2019-04-01 00:00:00

  • Bafilomycin A1 inhibits lysosomal, phagosomal, and plasma membrane H(+)-ATPase and induces lysosomal enzyme secretion in macrophages.

    abstract::Bafilomycin A1, a specific inhibitor of H(+)-ATPases of the vacuolar type, was in the present study shown, at similar concentrations, to induce secretion of lysosomal enzyme and to elevate lysosomal pH in mouse macrophages. These results lend support to the previous suggestion of a triggering role for an increase in l...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041630116

    authors: Tapper H,Sundler R

    更新日期:1995-04-01 00:00:00

  • Size-dependent hyaluronate degradation by cultured cells.

    abstract::Hyaluronate degradation was examined in cultures of vascular wall cells (bovine aortic endothelial cells, rat aortic smooth muscle cells) and in nonvascular cells (chick embryo fibroblasts). The three cell types examined all produced hyaluronidase activity in culture which had a strict acidic pH requirement for activi...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1041330210

    authors: McGuire PG,Castellot JJ Jr,Orkin RW

    更新日期:1987-11-01 00:00:00

  • p120-catenin is required for regulating epidermal proliferation, differentiation, and barrier function.

    abstract::p120-catenin (p120) is an important regulator in the function and stability of E-cadherin. However, the role of p120 in the epidermis is unclear. Previous studies have shown that globally knockout of p120 caused increased epidermal proliferation but little changes in epidermal differentiation and permeability. In the ...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.26535

    authors: Xie Z,Tang Y,Man MQ,Shrestha C,Bikle DD

    更新日期:2018-01-01 00:00:00

  • Evidence for variation in the number of functional gene copies at the AmaR locus in Chinese hamster cell lines.

    abstract::The hypothesis of functional hemizygosity has been examined for the alpha-amanitin resistant (AmaR, a codominant marker) locus in a series of Chinese hamster cell lines. AmaR mutants were obtained from different cell lines, e.g., CHO, DHW, M3- 1 and CHO-Kl, at similar frequencies. After fractionation of different RNA ...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1040970321

    authors: Gupta RS,Chan DY,Siminovitch L

    更新日期:1978-12-01 00:00:00

  • Ontogeny of human neutrophil granulocyte alkaline phosphatase.

    abstract::Human embryonic neutrophils (N) in the liver (from 8.5 mm crown-rump length) are alkaline phosphatase (AP) negative during the first trimester of pregnancy. Early bone marrow granulocytes (from eleventh to sixteenth weeks of gestation) behave similarly. Only a small percentage of slightly AP positive cells could be fo...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1040950313

    authors: Kelemen E,Gulya E,Vass K

    更新日期:1978-06-01 00:00:00

  • The effect of amino acids on the temperature sensitive phenotype of the mammalian leucyl-tRNA synthetase mutant tsHl and its revertants.

    abstract::The temperature sensitive leucyl-tRNA synthetase mutant tsHl and two revertants have been compared to the parental Chinese hamster ovary cells with respect to the effects of amino acid concentrations in the medium on growth. Elevating the leucine concentration 30- or 100-fold allowed tsHl to grow exponentially at 38.5...

    journal_title:Journal of cellular physiology

    pub_type: 杂志文章

    doi:10.1002/jcp.1040980208

    authors: Molnar SJ,Rauth AM

    更新日期:1979-02-01 00:00:00