Antibodies Against Mimotopes of Simian Virus 40 Large T Antigen, the Oncoprotein, in Serum Samples From Elderly Healthy Subjects.

abstract：:Elevated levels of follistatin-like protein 1 (FSTL1) have been found both in mouse models for human rheumatoid arthritis (RA) and collagen-induced arthritis (CIA). In this study, we elucidated the potential mechanisms by which FSTL1 contributes to the pathogenesis of RA. Fibroblast-like synoviocytes (FLSs) were estab...

journal_title：Journal of cellular physiology

authors： Ni S,Li C,Xu N,Liu X,Wang W,Chen W,Wang Y,van Wijnen AJ

更新日期：2018-01-01 00:00:00

abstract：:Characteristic features like self-renewal, multilineage differentiation potential, and immune-modulatory/anti-inflammatory properties, besides the ability to mobilize and home distant tissues make stem cells (SCs) a lifeline for an individual. Stem cells (SCs) if could be harvested and expanded without any abnormal ch...

journal_title：Journal of cellular physiology

authors： Gugjoo MB,Amarpal,Fazili MR,Shah RA,Sharma GT

更新日期：2019-06-01 00:00:00

abstract：:We can distinguish two classes of membrane transport changes in cultured cells: (a) growth-rate contingent changes are those which occur in coordination with the onset of density-dependent inhibition of growth; (b) transformation-specific changes are those which occur when cells become transformed, and which can be de...

journal_title：Journal of cellular physiology

authors： Weber MJ,Hale AH,Yau TM,Buckman T,Johnson M,Brady TM,LaRossa DD

更新日期：1976-12-01 00:00:00

abstract：:Liver fibrosis is a reversible wound-healing response that occurs after liver injury. NADPH oxidases (NOXs) and reactive oxygen species (ROS) which are expressed in hepatocytes (HCs), hepatic stellate cells (HSCs), and Kupffer cells (KCs) play an important role in the development of hepatic fibrosis. In in vitro studi...

journal_title：Journal of cellular physiology

authors： Gan D,Zhang W,Huang C,Chen J,He W,Wang A,Li B,Zhu X

更新日期：2018-10-01 00:00:00

abstract：:Connective tissue growth factor (CTGF) is a secreted, extracellular matrix-associated signaling protein that regulates diverse cellular functions. In vivo, CTGF is expressed in many tissues with highest levels in the kidney and brain. The purpose of this study was twofold; first, to localize CTGF in normal bone in viv...

journal_title：Journal of cellular physiology

authors： Safadi FF,Xu J,Smock SL,Kanaan RA,Selim AH,Odgren PR,Marks SC Jr,Owen TA,Popoff SN

更新日期：2003-07-01 00:00:00

abstract：:Prostate cancer (PCa) is one of the most common cancers and the fifth most common reason for cancer deaths in the males. Surgical castration combined with androgen deprivation therapy, antiandrogens, and androgen synthesis inhibitors is the current therapeutic modalities for PCa. These strategies inhibit androgen synt...

journal_title：Journal of cellular physiology

authors： Rezaei S,Mahjoubin Tehran M,Sahebkar A,Jalili A,Aghaee-Bakhtiari SH

更新日期：2020-04-01 00:00:00

abstract：:Gicerin/CD146 is a cell adhesion molecule, which belongs to the immunoglobulin (Ig) superfamily. We have reported that it has a homophilic binding activity, which participates in the neurite extension from embryonic neurons. To elucidate how gicerin is involved in the neurite extension mechanism, we employed PC12 cell...

journal_title：Journal of cellular physiology

authors： Taira E,Kohama K,Tsukamoto Y,Okumura S,Miki N

更新日期：2005-08-01 00:00:00

abstract：:Optical indicators of the cationic, cyanine and anionic oxonol classes were used to evaluate the plasma membrane potential of animal cells in suspension and in monolayer culture. The optical signals were calibrated by using diffusion potentials either of K+ (in the presence of valinomycin) or of H+ (in the presence of...

journal_title：Journal of cellular physiology

authors： Bashford CL,Alder GM,Gray MA,Micklem KJ,Taylor CC,Turek PJ,Pasternak CA

更新日期：1985-06-01 00:00:00

abstract：:Controlled-release drug delivery systems are promising platforms in medicine. Among various types of material in drug delivery, hydrogels are interesting ones. They are water-soluble and tissue compatible polymers with a high capacity to carry and release drugs in a controllable manner. In this study, we introduce the...

journal_title：Journal of cellular physiology

authors： Davoodi-Monfared P,Akbari-Birgani S,Mohammadi S,Kazemi F,Nikfarjam N,Nikbakht M,Mousavi SA

更新日期：2020-11-05 00:00:00

abstract：:In Xenopus oocytes injected with total rat pituitary GH3 cell RNA, thyrotropin-releasing hormone (TRH) causes the activation of the inositol lipid transduction pathway and the induction of chloride conductance via calcium-activated channels (Oron et al., 1987, Mol. Endocrinol., 1:918-925). This response exhibits chara...

journal_title：Journal of cellular physiology

authors： Lipinsky D,Gershengorn MC,Oron Y

更新日期：1995-02-01 00:00:00

abstract：:The single-copy gene of human basic fibroblast growth factor (bFGF) encodes four co-expressed isoforms, with an apparent molecular weight (M(r)) of 24 kD, 22.5 kD, 22 kD, and 18 kD, co-translated from a single mRNA. As a tool for the study of the role exerted by the different bFGF isoforms in the biology of endothelia...

journal_title：Journal of cellular physiology

authors： Gualandris A,Urbinati C,Rusnati M,Ziche M,Presta M

更新日期：1994-10-01 00:00:00

abstract：:Tfcp2l1 is a transcription factor critical for mouse embryonic stem cell (mESC) maintenance. However, its role in human ESCs (hESCs) remains unclear. Here, we investigated the role of Tfcp2l1 in controlling hESC activity and showed that Tfcp2l1 is functionally important in the maintenance of hESC identity. Tfcp2l1 exp...

journal_title：Journal of cellular physiology

authors： Sun H,You Y,Guo M,Wang X,Zhang Y,Ye S

更新日期：2018-09-01 00:00:00

abstract：:Smooth muscle cell (SMC) proliferation is a key process in stabilization of atherosclerotic plaques, and during restenosis after interventions. A clearer understanding of SMC growth regulation is therefore needed to design specific anti-proliferative therapies. Retinoic acid has been shown to inhibit proliferation of ...

journal_title：Journal of cellular physiology

authors： Tran-Lundmark K,Tannenberg P,Rauch BH,Ekstrand J,Tran PK,Hedin U,Kinsella MG

更新日期：2015-02-01 00:00:00

abstract：:The cells of the bone marrow microenvironment are emerging as important contributors and regulators of normal hematopoiesis. This microenvironment is perturbed during leukemogenesis, and evidence points toward a bidirectional communication between leukemia cells and the normal cells of the bone marrow, mediated by dir...

journal_title：Journal of cellular physiology

authors： Heath JL,Cohn GM,Zaidi SK,Stein GS

更新日期：2019-11-01 00:00:00

abstract：:NAD(P) is an indispensable cofactor for all organisms and its biosynthetic pathways are proposed as promising novel antibiotics targets against pathogens such as Mycobacterium tuberculosis. Six NAD(P) biosynthetic pathways were reconstructed by comparative genomics: de novo pathway (Asp), de novo pathway (Try), NmR pa...

journal_title：Journal of cellular physiology

authors： Bi J,Wang H,Xie J

更新日期：2011-02-01 00:00:00

abstract：:A previously described chondrocyte alkaline phosphatase induction factor (CAP-IF) for chicken epiphyseal growth plate chondrocytes has been purified to SDS-PAGE homogeneity from fetal bovine serum by ammonium sulfate precipitation and by dye-ligand affinity (Affi-Gel Blue and Reactive Green-19 agarose) and hydroxyapat...

journal_title：Journal of cellular physiology

authors： Ishikawa Y,Wu LN,Valhmu WB,Wuthier RE

更新日期：1991-11-01 00:00:00

abstract：:We have partially purified a mitogenic factor, termed colony stimulating factor, which is secreted from a human T lymphocytic cell line, and which stimulates in vitro formation of colonies of macrophages and granulocytes by human bone marrow cells. Colony stimulating factor (CSF) produced by cells grown in serum suppl...

journal_title：Journal of cellular physiology

authors： Frölich M

更新日期：1981-12-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is one of the main liver diseases today, and may progress to steatohepatitis, cirrhosis, and hepatocellular carcinoma. Some studies have shown the beneficial effects of aerobic exercise on reversing NAFLD. To verify whether chronic aerobic exercise improves the insulin resistan...

journal_title：Journal of cellular physiology

authors： Batatinha HA,Lima EA,Teixeira AA,Souza CO,Biondo LA,Silveira LS,Lira FS,Rosa Neto JC

更新日期：2017-05-01 00:00:00

abstract：:Macrophages are central mediators of the immune, contributing both to the initiation and the resolution of inflammation. The concept of macrophage activation and program has stimulated interest in its definition, and functional significance in homeostasis and diseases. It has been known that macrophages could be diffe...

journal_title：Journal of cellular physiology

authors： Liu G,Yang H

更新日期：2013-03-01 00:00:00

abstract：:IGF-I and its receptor IGF-IR are seen as critical effectors of muscle hypertrophy, a notion recently questioned. Using MKR transgenic mice that express a dominant negative IGF-IR only in skeletal muscle, we have examined the role of the IGF-IR signaling in differentiation and repair of muscle fibers after damage-indu...

journal_title：Journal of cellular physiology

authors： Heron-Milhavet L,Mamaeva D,LeRoith D,Lamb NJ,Fernandez A

更新日期：2010-10-01 00:00:00

abstract：:Alkaptonuria (AKU) is an ultra-rare genetic disease, in which the accumulation of a toxic metabolite, homogentisic acid (HGA) leads to the systemic development of ochronotic aggregates. These aggregates cause severe complications mainly at the level of joints with extensive degradation of the articular cartilage. Prim...

journal_title：Journal of cellular physiology

authors： Gambassi S,Geminiani M,Thorpe SD,Bernardini G,Millucci L,Braconi D,Orlandini M,Thompson CL,Petricci E,Manetti F,Taddei M,Knight MM,Santucci A

更新日期：2017-11-01 00:00:00

abstract：:Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2. Muc4/SMC can act as an intramembrane ligand for ErbB2 via an EGF-like ...

journal_title：Journal of cellular physiology

authors： Price-Schiavi SA,Andrechek E,Idris N,Li P,Rong M,Zhang J,Carothers Carraway CA,Muller WJ,Carraway KL

更新日期：2005-04-01 00:00:00

abstract：:Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein of 38 kDa in size, p38SJ, from a callus culture of Hypericum perforat...

journal_title：Journal of cellular physiology

authors： Amini S,Merabova N,Khalili K,Darbinian N

更新日期：2009-12-01 00:00:00

abstract：:Melanoma as the most major skin malignancy has attracted much attention, so far. Although a successful therapeutic strategy requires an accurate understanding of the precise mechanisms for the initiation and progression of the melanoma. Several types of cell death mechanisms have recently been identified along with co...

journal_title：Journal of cellular physiology

authors： Ashrafizadeh M,Mohammadinejad R,Tavakol S,Ahmadi Z,Roomiani S,Katebi M

更新日期：2019-11-01 00:00:00

abstract：:Cell hybrids were formed between human diploid fibroblasts (HDF) and carcinogen-transformed HDF to determine the relationship among: (1) finite proliferative lifespan, which we define as an age-related failure of a population to achieve one population doubling in 4 weeks; (2) arrest in a senescent state, which we defi...

journal_title：Journal of cellular physiology

authors： Stein GH,Namba M,Corsaro CM

更新日期：1985-03-01 00:00:00

abstract：:Osteoporosis, arthritis, Peget's disease, bone tumor, periprosthetic joint infection, and periprosthetic loosening have a common characteristic of osteolysis, which is characterized by the enhanced osteoclastic bone resorptive function. At present, the treatment target of these diseases is to interfere with osteoclast...

journal_title：Journal of cellular physiology

authors： Fu F,Shao S,Wang Z,Song F,Lin X,Ding J,Li C,Wu Z,Li K,Xiao Y,Su Y,Zhao J,Liu Q,Xu J

更新日期：2019-07-01 00:00:00

abstract：:Erythropoietin (EPO), the key hormone for erythropoiesis, also increases nitric oxide (NO) bioavailability in endothelial cells (ECs), yet the definitive mechanisms are not fully understood. Increasing evidence has demonstrated that β common receptor (βCR) plays a crucial role in EPO-mediated non-hematopoietic effects...

journal_title：Journal of cellular physiology

authors： Su KH,Shyue SK,Kou YR,Ching LC,Chiang AN,Yu YB,Chen CY,Pan CC,Lee TS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is characterized by the apoptosis resistance and hyperproliferation of pulmonary artery smooth muscle cells (PASMCs). Its pathogenesis has not been revealed. Here, we carried out experiments to investigate the functions of miR-140-5p and tumor necrosis factor-α (TNF-α). ...

journal_title：Journal of cellular physiology

authors： Zhu TT,Zhang WF,Yin YL,Liu YH,Song P,Xu J,Zhang MX,Li P

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Despite at the beginning known as a benign disease, endometriosis is defined as a risk factor for developing ovarian carcinoma. The effect of endometriosis on ovarian malignancy is known but its role in granulosa cell tumor is still unclear. METHODS AND MATERIALS:In this study, serum samples were collected ...

journal_title：Journal of cellular physiology

authors： Asghari S,Valizadeh Dizajeykan A,Ahmadi M,Barzegari A,Rikhtegar R,Dolati S,Danaii S,Abdollahi-Fard S,Nouri M,Mahdipour M,Yousefi M

更新日期：2019-07-01 00:00:00

abstract：:Mitofusin 2 (MFN2) is a regulatory protein participating in mitochondria dynamics, cell proliferation, death, differentiation, and so on. This study aims at revealing the functional role of MFN2 in the pluripotency maintenance and primitive differetiation of embryonic stem cell (ESCs). A dox inducible silencing and ro...

journal_title：Journal of cellular physiology

authors： Yi S,Cui C,Huang X,Yin X,Li Y,Wen J,Luan Q

更新日期：2020-02-01 00:00:00