Transfer of group A streptococcal pyrogenic exotoxin production to nontoxigenic strains of lysogenic conversion.

abstract：:Enterococcus faecalis is a highly stress resistant opportunistic pathogen. The intrinsic ruggedness of this bacterium is supposed to be the basis of its capacity to colonize the hostile environments of hospitals and to cause several kinds of infections. We show in this work that general resistance to very different en...

journal_title：Infection and immunity

authors： Rana NF,Sauvageot N,Laplace JM,Bao Y,Nes I,Rincé A,Posteraro B,Sanguinetti M,Hartke A

更新日期：2013-08-01 00:00:00

abstract：:Although protective immunity in C57BL/6 mice induced by a single dose of the radiation-attenuated schistosome vaccine is believed to be mediated by Th1-type immune responses, we here report that in BALB/c mice protection can also depend upon signaling via the interleukin-4 (IL-4) receptor which conventionally governs ...

journal_title：Infection and immunity

authors： Mountford AP,Hogg KG,Coulson PS,Brombacher F

更新日期：2001-01-01 00:00:00

abstract：:Experimental Helicobacter pylori infection was studied in Mongolian gerbils with fresh human isolates that carry or do not carry cagA (cagA-positive or cagA-negative, respectively), multiply passaged laboratory strains, wild-type strain G1.1, or isogenic ureA, cagA, or vacA mutants of G1.1. Animals were sacrificed 1 t...

journal_title：Infection and immunity

authors： Wirth HP,Beins MH,Yang M,Tham KT,Blaser MJ

更新日期：1998-10-01 00:00:00

abstract：:Bordetella pertussis, a causative agent of whooping cough, expresses BrkA, which confers serum resistance, but the closely related human pathogen that also causes whooping cough, Bordetella parapertussis, does not. Interestingly, B. parapertussis, but not B. pertussis, produces an O antigen, a factor shown in other mo...

journal_title：Infection and immunity

authors： Goebel EM,Wolfe DN,Elder K,Stibitz S,Harvill ET

更新日期：2008-04-01 00:00:00

abstract：:It was shown in this work that the infectivity of metacyclic forms of Trypanosoma cruzi was affected upon interaction with the monoclonal antibody (10D8), which reacts with a carbohydrate epitope of the 35- and 50-kilodalton (kDa) surface glycoconjugates. The invasion of Vero cells by metacyclic forms of strains Tulah...

journal_title：Infection and immunity

authors： Yoshida N,Mortara RA,Araguth MF,Gonzalez JC,Russo M

更新日期：1989-06-01 00:00:00

abstract：:Saliva-binding molecules of Streptococcus sanguis and their receptors were investigated. Streptococcal cell surfaces were extracted with a barbital buffer and examined immunochemically. Strains G9B and Blackburn, which adhere specifically to saliva-coated hydroxyapatite via immunologically related adhesins, possess 80...

journal_title：Infection and immunity

authors： Lamont RJ,Rosan B,Murphy GM,Baker CT

更新日期：1988-01-01 00:00:00

abstract：:The importance of CD4+ cells and gamma interferon (IFN-gamma) in the resolution of established Cryptosporidium parvum infection was investigated with a murine model of cryptosporidiosis in severe combined immunodeficient (SCID) mice. C. parvum-infected SCID mice were reconstituted with spleen cells from immunocompeten...

journal_title：Infection and immunity

authors： Chen W,Harp JA,Harmsen AG

更新日期：1993-09-01 00:00:00

abstract：:Pathogenic Yersinia species utilize a type III secretion system (T3SS) to translocate effectors called Yersinia outer proteins (Yops) into infected host cells. Previous studies demonstrated a role for effector Yops in the inhibition of caspase-1-mediated cell death and secretion of interleukin-1beta (IL-1beta) in naïv...

journal_title：Infection and immunity

authors： Lilo S,Zheng Y,Bliska JB

更新日期：2008-09-01 00:00:00

abstract：:We compared the immune defense of mice with chronic granulomatous disease (CGD mice) with that of wild-type C57BL/6 mice for their response to Sporothrix schenckii. A subcutaneous injection of 5 x 10(4) CFU S. schenckii strain IFM41598 into CGD mice resulted in systemic infection and death within 84 days. In contrast,...

journal_title：Infection and immunity

authors： Kajiwara H,Saito M,Ohga S,Uenotsuchi T,Yoshida S

更新日期：2004-09-01 00:00:00

abstract：:Glaesserella (Haemophilus) parasuis is a commensal bacterium of the upper respiratory tract in pigs and also the causative agent of Glässer's disease, which causes significant morbidity and mortality in pigs worldwide. Isolates are characterized into 15 serovars by their capsular polysaccharide, which has shown a corr...

journal_title：Infection and immunity

authors： Eberle KC,Hau SJ,Luan SL,Weinert LA,Stasko JA,Wang J,Peters SE,Langford PR,Rycroft AN,Wren BW,Maskell DJ,Tucker AW,Brockmeier SL

更新日期：2020-04-20 00:00:00

abstract：:Streptococcus pneumoniae interacts with vascular endothelial cells during the course of bacteremia. In this study, we characterized the initial attachment of pneumococci to human endothelial cells (EC) and the response of the endothelium to this interaction. Pneumococci adhered to EC in a dose-dependent fashion. Attac...

journal_title：Infection and immunity

authors： Geelen S,Bhattacharyya C,Tuomanen E

更新日期：1993-04-01 00:00:00

abstract：:The nucleotide sequences of three previously undescribed Pseudomonas aeruginosa pilin structural genes are presented. Comparisons of deduced pilin primary structure and flanking DNA sequence allowed placement of these and six previously published sequences into one of two groups. Epitope mapping, using overlapping imm...

journal_title：Infection and immunity

authors： Castric PA,Deal CD

更新日期：1994-02-01 00:00:00

abstract：:The intravascular trematode Schistosoma mansoni is a causative agent of schistosomiasis, a disease that constitutes a major health problem globally. In this study we cloned and characterized the schistosome tegumental phosphodiesterase SmNPP-5 and evaluated its role in parasite virulence. SmNPP-5 is a 52.5-kDa protein...

journal_title：Infection and immunity

authors： Bhardwaj R,Krautz-Peterson G,Da'dara A,Tzipori S,Skelly PJ

更新日期：2011-10-01 00:00:00

abstract：:A 46-kDa hemolytic protein, referred to as cystalysin, from Treponema denticola ATCC 35404 was overexpressed in Escherichia coli LC-67. Both the native and recombinant 46-kDa proteins were purified to homogeneity. Both proteins expressed identical biological and functional characteristics. In addition to its biologica...

journal_title：Infection and immunity

authors： Chu L,Ebersole JL,Kurzban GP,Holt SC

更新日期：1997-08-01 00:00:00

abstract：:Urease from ureaplasmas was purified by immunoaffinity chromatography, and the N-terminal amino acid sequence was determined for two of the three subunits. These sequences were used to design primers for a polymerase chain reaction (PCR) that amplified most of the gene coding for one of the subunits. By using a novel ...

journal_title：Infection and immunity

authors： Willoughby JJ,Russell WC,Thirkell D,Burdon MG

更新日期：1991-07-01 00:00:00

abstract：:Production of the Kanagawa hemolysin by patient strains of Vibrio parahaemolyticus was found to respond to the pH rather than to the type of carbohydrate present in the growth medium. Regardless of the carbohydrate present, hemolysin production in peptone broth cultures occurred only when the pH was between 6.5 and 5....

journal_title：Infection and immunity

authors： Cherwonogrodzky JW,Clark AG

更新日期：1981-10-01 00:00:00

abstract：:Considerable evidence supports the concept that CD4(+) T cells are important in sarcoidosis pathogenesis, but the antigens responsible for the observed Th1 immunophenotype remain elusive. The epidemiologic association with bioaerosols and the presence of granulomatous inflammation support consideration of mycobacteria...

journal_title：Infection and immunity

authors： Oswald-Richter KA,Culver DA,Hawkins C,Hajizadeh R,Abraham S,Shepherd BE,Jenkins CA,Judson MA,Drake WP

更新日期：2009-09-01 00:00:00

abstract：:The kinetics and homing characteristics of T-cell responses in humans after mucosal immunizations have not been well characterized. Therefore, we have investigated the magnitude and duration of such responses as well as the homing receptor expression of antigen-specific peripheral blood T cells by using an oral model ...

journal_title：Infection and immunity

authors： Lundin BS,Johansson C,Svennerholm AM

更新日期：2002-10-01 00:00:00

abstract：:The symptoms of Lyme disease are caused by inflammation induced by species of the Borrelia burgdorferisensu lato complex. The various presentations of Lyme disease in the population suggest that differences exist in the intensity and regulation of the host response to the spirochete. Previous work has described correl...

journal_title：Infection and immunity

authors： Siebers EM,Liedhegner ES,Lawlor MW,Schell RF,Nardelli DT

更新日期：2020-10-19 00:00:00

abstract：:Swine were infected orally with pure cultures of Treponema hyodysenteriae, and the humoral antibody response was measured by a passive hemolysis test (passive hemagglutination test with the use of complement). Antibody to T. hyodysenteriae was detected as early as 1 week and later on at 4 months after exposure. Howeve...

journal_title：Infection and immunity

authors： Jenkins EM,Sinha PP,Vance RT,Reese GL

更新日期：1976-10-01 00:00:00

abstract：:This work evaluated the kinetics of events that occur in the placenta of Calomys callosus after Toxoplasma gondii infection. Animals on the first day of pregnancy (dop) and virgin nonpregnant females were perorally infected with 20 cysts of T. gondii strain ME49. After 100 days of infection, the virgin animals were ma...

journal_title：Infection and immunity

authors： Ferro EA,Silva DA,Bevilacqua E,Mineo JR

更新日期：2002-12-01 00:00:00

abstract：:Ureaplasma urealyticum is a common commensal of the female lower urogenital tract, yet it has been shown to be an important cause of chorioamnion infection, respiratory and central nervous system disease, and death in premature infants. It has been suggested that only certain serovars are capable of producing invasive...

journal_title：Infection and immunity

authors： Zheng X,Teng LJ,Watson HL,Glass JI,Blanchard A,Cassell GH

更新日期：1995-03-01 00:00:00

abstract：:In an earlier report, we had described the isolation and characterization of autolysis-defective mutants of Staphylococcus aureus (N. Mani, P. Tobin, and R.K. Jayaswal, J. Bacteriol. 175:1493-1499, 1993). In the study reported here, an autolysis-defective mutant showed attenuated virulence in a rat model of experiment...

journal_title：Infection and immunity

authors： Mani N,Baddour LM,Offutt DQ,Vijaranakul U,Nadakavukaren MJ,Jayaswal RK

更新日期：1994-04-01 00:00:00

abstract：:Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The outer membrane protein compositions of aerobically and anaerobically grown N. gonorrhoeae strains were compared by one- a...

journal_title：Infection and immunity

authors： Clark VL,Campbell LA,Palermo DA,Evans TM,Klimpel KW

更新日期：1987-06-01 00:00:00

abstract：:CD8 T cells are effective mediators of specific immunity to infection by Listeria monocytogenes, a bacterial pathogen that initially infects macrophages in the spleen and liver and subsequently spreads to hepatocytes and unidentified parenchymal cells in the spleen. To identify the in vivo target cells of L. monocytog...

journal_title：Infection and immunity

authors： Harty JT,Bevan MJ

更新日期：1996-09-01 00:00:00

abstract：:Monoclonal antibodies against Ureaplasma urealyticum serotype 4 were produced by immunizing BALB/c mice with whole-cell antigens of the U. urealyticum serotype 4 reference strain. Ten monoclonal antibodies differentiated into two groups were found: one group included five monoclonal antibodies recognizing a band in im...

journal_title：Infection and immunity

authors： Cheng X,Naessens A,Lauwers S

更新日期：1993-05-01 00:00:00

abstract：:Mucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and the role of T cells in host defense against mucosal fungal infections are not known. H...

journal_title：Infection and immunity

authors： Porter PC,Roberts L,Fields A,Knight M,Qian Y,Delclos GL,Han S,Kheradmand F,Corry DB

更新日期：2011-11-01 00:00:00

abstract：:Growth in colonies with type 1 morphology and the presence of pili are characteristics that have been associated with virulence of gonococci for humans. To determine whether the presence of pili per se might be responsible for colony type 1 morphology, the relationship of pili to colony type was examined in various sp...

journal_title：Infection and immunity

authors： McGee ZA,Dourmashkin RR,Gross JG,Clark JB,Taylor-Robinson D

更新日期：1977-02-01 00:00:00

abstract：:The kinetics of cytotoxic T lymphocyte antigen 4 (CTLA-4) expression on T cells responding to Cryptococcus neoformans and its role in regulating the T-cell response were examined. Using peripheral blood mononuclear cells stimulated with encapsulated or acapsular C. neoformans we showed that (i) the encapsulated strain...

journal_title：Infection and immunity

authors： Pietrella D,Perito S,Bistoni F,Vecchiarelli A

更新日期：2001-03-01 00:00:00

abstract：:High levels of Treponema denticola in subgingival dental plaque are associated with severe periodontal disease. T. denticola, along with Porphyromonas gingivalis and Bacteroides forsythus, are the only cultivatable oral microorganisms that produce significant amounts of "trypsin-like" peptidase activity. The ability o...

journal_title：Infection and immunity

authors： Fenno JC,Lee SY,Bayer CH,Ning Y

更新日期：2001-10-01 00:00:00